List of works - Cong Ma

A vector system that allows simple generation of mutant Escherichia coli RNA polymerase.

scientific article

Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs

scientific article

Bacterial Transcription Inhibitor of RNA Polymerase Holoenzyme Formation by Structure-Based Drug Design: From in Silico Screening to Validation

scientific article

Bacterial Transcription as a Target for Antibacterial Drug Development.

scientific article published on 13 January 2016

Cascade Metathesis Reactions for the Synthesis of Taxane and Isotaxane Derivatives

scientific article published on 8 April 2016

Catalytic asymmetric C-N bond formation: phosphine-catalyzed intra- and intermolecular γ-addition of nitrogen nucleophiles to allenoates and alkynoates

scientific article published on 21 January 2013

Design, Synthesis and Antibacterial Evaluation of 3-Substituted Ocotillol-Type Derivatives

Design, synthesis and biological evaluation of antimicrobial diarylimine and -amine compounds targeting the interaction between the bacterial NusB and NusE proteins

scientific article published on 03 June 2019

Design, synthesis and biological evaluation of pyridine-chalcone derivatives as novel microtubule-destabilizing agents

scientific article published on 06 April 2019

Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site

scientific article published on 29 November 2018

Design, synthesis, and biological evaluation of truncated deguelin derivatives as Hsp90 inhibitors

scientific article published on 12 February 2019

Design, synthesis, nitric oxide release and antibacterial evaluation of novel nitrated ocotillol-type derivatives

scientific article

Discovery of Antibacterials That Inhibit Bacterial RNA Polymerase Interactions with Sigma Factors

scientific article published on 07 July 2020

Discovery of Novel Inhibitors Targeting Multi-UDP-hexose Pyrophosphorylases as Anticancer Agents

scientific article published on 03 February 2020

Discovery of Novel Quinoline-Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity

scientific article published on 24 December 2018

First-In-Class Inhibitor of Ribosomal RNA Synthesis with Antimicrobial Activity against Staphylococcus aureus.

scientific article

First-In-Class Inhibitors Targeting the Interaction between Bacterial RNA Polymerase and Sigma Initiation Factor Affect the Viability and Toxin Release of Streptococcus pneumoniae

scientific article published on 09 August 2019

From indole to pyrrole, furan, thiophene and pyridine: Search for novel small molecule inhibitors of bacterial transcription initiation complex formation.

scientific article published on 21 January 2016

HPLC, quantitative NMR and HRMS spectroscopic data of nusbiarylins as a new class of antimicrobial agents

scientific article published on 21 February 2020

Highly efficient synthesis of the tricyclic core of Taxol by cascade metathesis

scientific article published on 05 June 2014

Identification and validation of small molecule modulators of the NusB-NusE interaction.

scientific article

Identification of inhibitors of bacterial RNA polymerase

scientific article published on 12 May 2015

In Vitro Transcription Assays and Their Application in Drug Discovery.

scientific article published on 20 September 2016

Inhibitors of bacterial transcription initiation complex formation.

scientific article published on 5 July 2013

Metal-Free Synthesis of N-(Pyridine-2-yl)amides from Ketones via Selective Oxidative Cleavage of C(O)-C(Alkyl) Bond in Water

scientific article published on 27 November 2018

Novel 3-substituted ocotillol-type triterpenoid derivatives as antibacterial candidates

scientific article published on 20 May 2014

Novel N-Substituted oseltamivir derivatives as potent influenza neuraminidase inhibitors: Design, synthesis, biological evaluation, ADME prediction and molecular docking studies

scientific article published on 22 August 2019

Nusbiarylins Inhibit Transcription and Target Virulence Factors in Bacterial Pathogen Staphylococcus aureus

scientific article published on 11 August 2020

Nusbiarylins, a new class of antimicrobial agents: Rational design of bacterial transcription inhibitors targeting the interaction between the NusB and NusE proteins

scientific article published on 16 August 2019

RNA polymerase-induced remodelling of NusA produces a pause enhancement complex.

scientific article

Ring-closing metathesis in the synthesis of BC ring-systems of taxol

scientific article published in January 2008

Simple Method for Studying in Vitro Protein-Protein Interactions Based on Protein Complementation and Its Application in Drug Screening Targeting Bacterial Transcription

scientific article published on 06 March 2019

Small molecule inhibitors of bacterial transcription complex formation

scientific article published on 19 August 2017

Small-Molecule Inhibitors of the NusB-NusE Protein-Protein Interaction with Antibiotic Activity

scientific article published on 25 July 2017

Synthesis and Antibacterial Evaluation of Novel 3-Substituted Ocotillol-Type Derivatives as Leads.

scientific article published on 7 April 2017

Synthesis and biological activity of novel bis-indole inhibitors of bacterial transcription initiation complex formation.

scientific article

Synthesis and biological activity of novel mono-indole and mono-benzofuran inhibitors of bacterial transcription initiation complex formation.

scientific article published on 25 February 2015

Synthesis and biological evaluation of 2,5-di(7-indolyl)-1,3,4-oxadiazoles, and 2- and 7-indolyl 2-(1,3,4-thiadiazolyl)ketones as antimicrobials.

scientific article

Synthesis and biological evaluation of novel ocotillol-type triterpenoid derivatives as antibacterial agents

scientific article published on 09 August 2013

Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site

scientific article published on 10 December 2018

List of works by Cong Ma

A vector system that allows simple generation of mutant Escherichia coli RNA polymerase.

Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs

Bacterial Transcription Inhibitor of RNA Polymerase Holoenzyme Formation by Structure-Based Drug Design: From in Silico Screening to Validation

Bacterial Transcription as a Target for Antibacterial Drug Development.

Cascade Metathesis Reactions for the Synthesis of Taxane and Isotaxane Derivatives

Catalytic asymmetric C-N bond formation: phosphine-catalyzed intra- and intermolecular γ-addition of nitrogen nucleophiles to allenoates and alkynoates

Design, Synthesis and Antibacterial Evaluation of 3-Substituted Ocotillol-Type Derivatives

Design, synthesis and biological evaluation of antimicrobial diarylimine and -amine compounds targeting the interaction between the bacterial NusB and NusE proteins

Design, synthesis and biological evaluation of pyridine-chalcone derivatives as novel microtubule-destabilizing agents

Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site

Design, synthesis, and biological evaluation of truncated deguelin derivatives as Hsp90 inhibitors

Design, synthesis, nitric oxide release and antibacterial evaluation of novel nitrated ocotillol-type derivatives

Discovery of Antibacterials That Inhibit Bacterial RNA Polymerase Interactions with Sigma Factors

Discovery of Novel Inhibitors Targeting Multi-UDP-hexose Pyrophosphorylases as Anticancer Agents

Discovery of Novel Quinoline-Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity

First-In-Class Inhibitor of Ribosomal RNA Synthesis with Antimicrobial Activity against Staphylococcus aureus.

First-In-Class Inhibitors Targeting the Interaction between Bacterial RNA Polymerase and Sigma Initiation Factor Affect the Viability and Toxin Release of Streptococcus pneumoniae

From indole to pyrrole, furan, thiophene and pyridine: Search for novel small molecule inhibitors of bacterial transcription initiation complex formation.

HPLC, quantitative NMR and HRMS spectroscopic data of nusbiarylins as a new class of antimicrobial agents

Highly efficient synthesis of the tricyclic core of Taxol by cascade metathesis

Identification and validation of small molecule modulators of the NusB-NusE interaction.

Identification of inhibitors of bacterial RNA polymerase

In Vitro Transcription Assays and Their Application in Drug Discovery.

Inhibitors of bacterial transcription initiation complex formation.

Metal-Free Synthesis of N-(Pyridine-2-yl)amides from Ketones via Selective Oxidative Cleavage of C(O)-C(Alkyl) Bond in Water

Novel 3-substituted ocotillol-type triterpenoid derivatives as antibacterial candidates

Novel N-Substituted oseltamivir derivatives as potent influenza neuraminidase inhibitors: Design, synthesis, biological evaluation, ADME prediction and molecular docking studies

Nusbiarylins Inhibit Transcription and Target Virulence Factors in Bacterial Pathogen Staphylococcus aureus

Nusbiarylins, a new class of antimicrobial agents: Rational design of bacterial transcription inhibitors targeting the interaction between the NusB and NusE proteins

RNA polymerase-induced remodelling of NusA produces a pause enhancement complex.

Ring-closing metathesis in the synthesis of BC ring-systems of taxol

Simple Method for Studying in Vitro Protein-Protein Interactions Based on Protein Complementation and Its Application in Drug Screening Targeting Bacterial Transcription

Small molecule inhibitors of bacterial transcription complex formation

Small-Molecule Inhibitors of the NusB-NusE Protein-Protein Interaction with Antibiotic Activity

Synthesis and Antibacterial Evaluation of Novel 3-Substituted Ocotillol-Type Derivatives as Leads.

Synthesis and biological activity of novel bis-indole inhibitors of bacterial transcription initiation complex formation.

Synthesis and biological activity of novel mono-indole and mono-benzofuran inhibitors of bacterial transcription initiation complex formation.

Synthesis and biological evaluation of 2,5-di(7-indolyl)-1,3,4-oxadiazoles, and 2- and 7-indolyl 2-(1,3,4-thiadiazolyl)ketones as antimicrobials.

Synthesis and biological evaluation of novel ocotillol-type triterpenoid derivatives as antibacterial agents

Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site