List of works by Susan Weiss

A novel full-length isoform of murine pregnancy-specific glycoprotein 16 (psg16) is expressed in the brain but does not mediate murine coronavirus (MHV) entry

scientific article

A novel mechanism of RNase L inhibition: Theiler's virus L* protein prevents 2-5A from binding to RNase L.

scientific article published on 13 April 2018

A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency

scientific article published on 21 September 2020

Activation of RNase L by Murine Coronavirus in Myeloid Cells Is Dependent on Basal Oas Gene Expression and Independent of Virus-Induced Interferon

scientific article published on 6 January 2016

Activation of RNase L in Egyptian Rousette Bat-Derived RoNi/7 Cells Is Dependent Primarily on OAS3 and Independent of MAVS Signaling.

scientific article published on 12 November 2019

Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses

scientific article published on 8 February 2016

Amino acid substitutions within the heptad repeat domain 1 of murine coronavirus spike protein restrict viral antigen spread in the central nervous system

scientific article published on 01 August 2003

Analysis of Newcastle disease virus messenger RNA and poly (A)

Analysis of the host transcriptome from demyelinating spinal cord of murine coronavirus-infected mice

scientific article

Antagonism of RNase L Is Required for Murine Coronavirus Replication in Kupffer Cells and Liver Sinusoidal Endothelial Cells but Not in Hepatocytes.

scientific article published on 24 August 2016

Antagonism of dsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins during MERS Coronavirus Infection

scholarly article by Courtney E Comar published in March 2019

Antagonism of the interferon-induced OAS-RNase L pathway by murine coronavirus ns2 protein is required for virus replication and liver pathology

scientific article published on June 2012

Both spike and background genes contribute to murine coronavirus neurovirulence

scientific article

CD8+ T-cell priming during a central nervous system infection with mouse hepatitis virus

scientific article published in January 2006

Cannabis and the Opioid Crisis.

scientific article

Cell-type-specific activation of the oligoadenylate synthetase-RNase L pathway by a murine coronavirus.

scientific article published on 22 May 2013

Cell-type-specific effects of RNase L on viral induction of beta interferon

scientific article published on 25 February 2014

Cell-type-specific type I interferon antagonism influences organ tropism of murine coronavirus

scientific article

Chemokine expression during mouse-hepatitis-virus-induced encephalitis: contributions of the spike and background genes

scientific article published in January 2008

Conformational changes in the spike glycoprotein of murine coronavirus are induced at 37 degrees C either by soluble murine CEACAM1 receptors or by pH 8.

scientific article

Contributions of the viral genetic background and a single amino acid substitution in an immunodominant CD8+ T-cell epitope to murine coronavirus neurovirulence

scientific article

Coronavirus pathogenesis

scientific article

Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus

scientific article

Coronavirus replication and pathogenesis: Implications for the recent outbreak of severe acute respiratory syndrome (SARS), and the challenge for vaccine development.

scientific article published on April 2004

Coronavirus-induced demyelination of neural pathways triggers neurogenic bladder overactivity in a mouse model of multiple sclerosis.

scientific article

Crystal structure of the mouse hepatitis virus ns2 phosphodiesterase domain that antagonizes RNase L activation

scientific article

DMSO induced myocardial infarction during allogeneic cryopreserved bone marrow transplant

scientific article published on 20 August 2014

Demyelinating and nondemyelinating strains of mouse hepatitis virus differ in their neural cell tropism

scientific article published on 2 April 2008

Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication

scientific article

Effects of an epitope-specific CD8+ T-cell response on murine coronavirus central nervous system disease: protection from virus replication and antigen spread and selection of epitope escape mutants

scientific article published on February 2004

Endosomal proteolysis by cathepsins is necessary for murine coronavirus mouse hepatitis virus type 2 spike-mediated entry

scientific article published on June 2006

Enhanced expression and purification of membrane proteins by SUMO fusion in Escherichia coli

scientific article

Enhanced green fluorescent protein expression may be used to monitor murine coronavirus spread in vitro and in the mouse central nervous system

scientific article published on October 2002

Evaluation of SSYA10-001 as a replication inhibitor of severe acute respiratory syndrome, mouse hepatitis, and Middle East respiratory syndrome coronaviruses

scientific article published on 19 May 2014

Expression and purification of SARS coronavirus proteins using SUMO-fusions.

scientific article published on 23 February 2005

Expression of hemagglutinin esterase protein from recombinant mouse hepatitis virus enhances neurovirulence

scientific article published on December 2005

Further in vitro characterization of mouse hepatitis virus papain-like proteinase 1: cleavage sequence requirements within pp1a

scientific article published in April 2002

Genetic determinants of mouse hepatitis virus strain 1 pneumovirulence

scientific article

Homologous 2',5'-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity

scientific article published on 22 July 2013

How we treat: risk mitigation for ABO-incompatible plasma in plateletpheresis products

scientific article published on 13 March 2012

Identification and Characterization of a 65-kDa Protein Processed from the Gene 1 Polyprotein of the Murine Coronavirus MHV-A59

article

Identification of murine CD8 T cell epitopes in codon-optimized SARS-associated coronavirus spike protein

scientific article

Increased epitope-specific CD8+ T cells prevent murine coronavirus spread to the spinal cord and subsequent demyelination

scientific article

Inhibition of the alpha/beta interferon response by mouse hepatitis virus at multiple levels

scientific article published on 25 April 2007

Lineage A Betacoronavirus NS2 Proteins and the Homologous Torovirus Berne pp1a Carboxy-Terminal Domain Are Phosphodiesterases That Antagonize Activation of RNase L.

scientific article published on 21 December 2016

MDA5 Is Critical to Host Defense during Infection with Murine Coronavirus.

scientific article published on 30 September 2015

MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells

scientific article published in 2022

Mechanism of nucleic acid unwinding by SARS-CoV helicase.

scientific article

Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation.

scientific article published on 29 March 2016

Molecular model of SARS coronavirus polymerase: implications for biochemical functions and drug design

scientific article

Moving the Fence—Municipal Boundary Changes Through Secession, Incorporation and Annexation

Murine AKAP7 has a 2',5'-phosphodiesterase domain that can complement an inactive murine coronavirus ns2 gene.

scientific article

Murine Coronavirus Cell Type Dependent Interaction with the Type I Interferon Response

scientific article published on December 2009

Murine Coronavirus Mouse Hepatitis Virus Is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/Microglia

scientific article (publication date: October 2008)

Murine coronavirus delays expression of a subset of interferon-stimulated genes

scientific article published on 31 March 2010

Murine coronavirus evolution in vivo: functional compensation of a detrimental amino acid substitution in the receptor binding domain of the spike glycoprotein.

scientific article

Murine coronavirus neuropathogenesis: determinants of virulence

scientific article

Murine coronavirus receptors are differentially expressed in the central nervous system and play virus strain-dependent roles in neuronal spread

scientific article

Murine coronavirus spike glycoprotein mediates degree of viral spread, inflammation, and virus-induced immunopathology in the central nervous system

scientific article published in September 2002

Murine coronavirus-induced hepatitis: JHM genetic background eliminates A59 spike-determined hepatotropism

scientific article

Murine hepatitis virus nsp14 exoribonuclease activity is required for resistance to innate immunity

scientific article published on 18 October 2017

Murine hepatitis virus strain 1 produces a clinically relevant model of severe acute respiratory syndrome in A/J mice.

scientific article

Neurovirulent Murine Coronavirus JHM.SD Uses Cellular Zinc Metalloproteases for Virus Entry and Cell-Cell Fusion

scientific article published on February 2017

No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2

scientific article published on 26 February 2020

Novel inhibitors of severe acute respiratory syndrome coronavirus entry that act by three distinct mechanisms

scientific article

OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug

scientific article

Organ-specific attenuation of murine hepatitis virus strain A59 by replacement of catalytic residues in the putative viral cyclic phosphodiesterase ns2.

scientific article published on 28 January 2009

Origins and pathogenesis of Middle East respiratory syndrome-associated coronavirus: recent advances

scientific article published on September 2017

Pathogenesis of murine coronavirus in the central nervous system

scientific article

Pathogenesis of neurotropic murine coronavirus is multifactorial

scientific article published on 7 December 2010

Perforin-mediated CTL cytolysis counteracts direct cell-cell spread of Listeria monocytogenes.

scientific article published in November 2002

Primary Role for Toll-Like Receptor-Driven Tumor Necrosis Factor Rather than Cytosolic Immune Detection in Restricting Coxiella burnetii Phase II Replication within Mouse Macrophages

scientific article published on 19 January 2016

Priming of CD8+ T cells during central nervous system infection with a murine coronavirus is strain dependent

scientific article published on 16 April 2008

RNase L is a negative regulator of cell migration

scientific article published on 27 October 2015

Radiography: a review for the rehabilitation professional

scientific article published on April 2007

Replicase genes of murine coronavirus strains A59 and JHM are interchangeable: differences in pathogenesis map to the 3' one-third of the genome.

scientific article published on November 2006

Replication defective viral genomes exploit a cellular pro-survival mechanism to establish paramyxovirus persistence.

scientific article published on 6 October 2017

Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line

scientific article

Role of the inflammasome-related cytokines Il-1 and Il-18 during infection with murine coronavirus

scientific article published on 11 September 2017

Role of the replicase gene of murine coronavirus JHM strain in hepatitis.

scientific article published on January 2006

SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial derived cells and cardiomyocytes

scientific article published on 25 September 2020

SARS: lessons learned from other coronaviruses.

scientific article published on January 2003

Sabadinine: a potential non-peptide anti-severe acute-respiratory-syndrome agent identified using structure-aided design

scientific article published in February 2004

Severe acute respiratory syndrome coronavirus replication inhibitor that interferes with the nucleic acid unwinding of the viral helicase

scientific article

Single-amino-acid substitutions in open reading frame (ORF) 1b-nsp14 and ORF 2a proteins of the coronavirus mouse hepatitis virus are attenuating in mice

scientific article published on March 2005

Splinting the degenerative basal joint: custom-made or prefabricated neoprene?

scientific article

Structural basis for 2'-5'-oligoadenylate binding and enzyme activity of a viral RNase L antagonist.

scientific article published on July 2015

Subcellular Detection of SARS-CoV-2 RNA in Human Tissue Reveals Distinct Localization in Alveolar Type 2 Pneumocytes and Alveolar Macrophages

scientific article published on 08 February 2022

Systematic assembly of a full-length infectious cDNA of mouse hepatitis virus strain A59.

scientific article

Targeted Mutations in the Fusion Peptide Region of La Crosse Virus Attenuate Neuroinvasion and Confer Protection against Encephalitis

scientific article published on 05 July 2022

The N-terminal domain of the murine coronavirus spike glycoprotein determines the CEACAM1 receptor specificity of the virus strain

scientific article

The SARS-CoV ferret model in an infection-challenge study.

scientific article

The glycosylation status of the murine hepatitis coronavirus M protein affects the interferogenic capacity of the virus in vitro and its ability to replicate in the liver but not the brain

scientific article published in August 2003

The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host

scientific article published on 01 April 2002

The murine coronavirus nucleocapsid gene is a determinant of virulence

scientific article published on 9 December 2009

The nsp1, nsp13, and M proteins contribute to the hepatotropism of murine coronavirus JHM.WU.

scientific article

The role of interferon antagonist, non-structural proteins in the pathogenesis and emergence of arboviruses

scientific article

The spike glycoprotein of murine coronavirus MHV-JHM mediates receptor-independent infection and spread in the central nervous systems of Ceacam1a-/- Mice

scientific article

The virulence of mouse hepatitis virus strain A59 is not dependent on efficient spike protein cleavage and cell-to-cell fusion

scientific article published in October 2002

Viral phosphodiesterases that antagonize double-stranded RNA signaling to RNase L by degrading 2-5A

scientific article

Virologic testing in the management of perinatal HIV exposure.

scientific article

Zika Virus Production Is Resistant to RNase L Antiviral Activity

scientific article published on 30 July 2019

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