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List of works by Marzia Del Re

2PD Monitoring of secondary drug resistance mutations in circulating tumor DNA of patients with advanced ALK positive NSCLC.

scientific article published on 15 April 2016

4th ESPT Conference: pharmacogenomics and personalized medicine - research progress and clinical implementation

scientific article published on 01 October 2019

A clinical pharmacogenetic characterization of DPD polymorphisms for pre-treatment screening of patients candidates to fluoropyrimidine therapy.

scientific article published on 11 February 2014

AR-V7 and AR-FL expression is associated with clinical outcome: a translational study in patients with castrate resistant prostate cancer

scientific article published on 04 May 2019

Androgens alter the heterogeneity of small extracellular vesicles and the small RNA cargo in prostate cancer

scientific article published on 18 August 2021

Angiogenic inhibitors in gastric cancers and gastroesophageal junction carcinomas: A critical insight

scientific article published on 05 March 2015

Application of a pharmacokinetic/pharmacogenetic approach to assess the nicotine metabolic profile of smokers in the real-life setting.

scientific article published on 31 August 2016

Author's reply: To PMID 22443211.

scientific article

Blood-based PD-L1 analysis in tumor-derived extracellular vesicles: Applications for optimal use of anti-PD-1/PD-L1 axis inhibitors

scientific article published on 30 October 2020

CYP17A1 polymorphism c.-362T>C predicts clinical outcome in metastatic castration-resistance prostate cancer patients treated with abiraterone

scientific article published on 18 September 2020

Circulating DNA in diagnosis and monitoring EGFR gene mutations in advanced non-small cell lung cancer

scientific article

Circulating biomarkers of response to immunotherapy in cancer treatment

scientific article published on 06 November 2019

Clinical pharmacology of intravitreal anti-VEGF drugs.

scientific article

Comparative evaluation of molecular methods for the quantitative measure of torquetenovirus viremia, the new surrogate marker of immune competence

scientific article published on 19 April 2019

Comparison of variant allele frequency and number of mutant molecules as units of measurement for circulating tumor DNA

scientific article published on 18 October 2020

Concise Review: Chronic Myeloid Leukemia: Stem Cell Niche and Response to Pharmacologic Treatment

scientific article published on 8 February 2018

Concise Review: Resistance to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer: The Role of Cancer Stem Cells.

scientific article published on 20 January 2018

Contribution of KRAS mutations and c.2369C > T (p.T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA.

scientific article published on 20 January 2016

Critical focus on mechanisms of resistance and toxicity of m-TOR inhibitors in pancreatic neuroendocrine tumors

scientific article

Crizotinib Resensitization by Compound Mutation.

scientific article

Cross-Linked Hyaluronic Acid as Tear Film Substitute

scientific article published on 02 August 2019

DPYD and UGT1A1 genotyping to predict adverse events during first-line FOLFIRI or FOLFOXIRI plus bevacizumab in metastatic colorectal cancer.

scientific article published on 21 December 2017

DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients

scientific article published on 06 February 2019

Dabrafenib treatment in a patient with BRAF V600E ganglioglioma: circulating exosome-derived cancer RNA supports treatment choice and clinical monitoring

scientific article published on 01 December 2019

Detection of ALK and KRAS Mutations in Circulating Tumor DNA of Patients With Advanced ALK-Positive NSCLC With Disease Progression During Crizotinib Treatment.

scientific article

Detection of KRAS mutant alleles in circulating cell-free tumor DNA in colorectal cancer patients resistant to cetuximab

scientific article published on 11 February 2014

Determinants of bone specific metastasis in prostate cancer.

scientific article published on 16 February 2017

Dihydropyrimidine dehydrogenase polymorphisms and fluoropyrimidine toxicity: ready for routine clinical application within personalized medicine?

scientific article

Discovery of novel mutations in the dihydropyrimidine dehydrogenase gene associated with toxicity of fluoropyrimidines and viewpoint on preemptive pharmacogenetic screening in patients

scientific article published on 2 September 2015

Drug-drug interactions in breast cancer patients treated with CDK4/6 inhibitors

scientific article published on 19 January 2019

EGFR-TKIs in non-small-cell lung cancer: focus on clinical pharmacology and mechanisms of resistance

scientific article published on 22 May 2018

Early changes in plasma DNA levels of mutant KRAS as a sensitive marker of response to chemotherapy in pancreatic cancer.

scientific article

Effects of amiodarone, thyroid hormones and CYP2C9 and VKORC1 polymorphisms on warfarin metabolism: a review of the literature.

scientific article

Endothelial nitric oxide synthase c.-813C>T predicts for proteinuria in metastatic breast cancer patients treated with bevacizumab-based chemotherapy

scientific article published on 16 September 2019

From the beginning to resistance: Study of plasma monitoring and resistance mechanisms in a cohort of patients treated with osimertinib for advanced T790M-positive NSCLC

scientific article published on 19 March 2019

Genetic variation: effect on prostate cancer.

scientific article

IL-8 and eNOS polymorphisms predict bevacizumab-based first line treatment outcomes in RAS mutant metastatic colorectal cancer patients

scientific article published on 25 January 2017

Identification of a targetable KRAS-mutant epithelial population in non-small cell lung cancer

scientific article published on 14 April 2021

Implications of KRAS mutations in acquired resistance to treatment in NSCLC.

scientific article published on 21 December 2017

Incidence of T790M in Patients With NSCLC Progressed to Gefitinib, Erlotinib, and Afatinib: A Study on Circulating Cell-free DNA

scientific article published on 13 October 2019

Investigational therapies targeting signal transducer and activator of transcription 3 for the treatment of cancer

scientific article

Large-Scale Profiling of Extracellular Vesicles Identified miR-625-5p as a Novel Biomarker of Immunotherapy Response in Advanced Non-Small-Cell Lung Cancer Patients

scientific article published on 14 May 2022

Mathematical modeling of drug resistance due to KRAS mutation in colorectal cancer

scientific article published on 6 November 2015

Methods: for studying pharmacogenetic profiles of combination chemotherapeutic drugs

scientific article published on 03 June 2015

Molecular analysis of cell-free circulating DNA for the diagnosis of somatic mutations associated with resistance to tyrosine kinase inhibitors in non-small-cell lung cancer

scientific article published on 11 April 2014

Optimized granulocyte colony-stimulating factor prophylaxis in adult cancer patients: from biological principles to clinical guidelines.

scientific article published on 23 March 2012

Overexpression of TK1 and CDK9 in plasma-derived exosomes is associated with clinical resistance to CDK4/6 inhibitors in metastatic breast cancer patients

scientific article published on 26 July 2019

PD-L1 mRNA expression in plasma-derived exosomes is associated with response to anti-PD-1 antibodies in melanoma and NSCLC

scientific article published on 06 March 2018

PI3K mutations detected in liquid biopsy are associated to reduced sensitivity to CDK4/6 inhibitors in metastatic breast cancer patients

scientific article published on 10 October 2020

PROMs in post-mastectomy care: Patient self-reports (BREAST-Q™) as a powerful instrument to personalize medical services

scientific article published on 27 November 2019

Pathophysiology and pharmacological targets of VEGF in diabetic macular edema.

scientific article

Patients with NSCLC may display a low ratio of p.T790M vs. activating EGFR mutations in plasma at disease progression: implications for personalised treatment.

scientific article published on 15 September 2017

Pharmacogenetic Foundations of Therapeutic Efficacy and Adverse Events of Statins

scientific article

Pharmacogenetic interaction analysis of VEGFR-2 and IL-8 polymorphisms in advanced breast cancer patients treated with paclitaxel and bevacizumab.

scientific article published in December 2014

Pharmacogenetics and Metabolism from Science to Implementation in Clinical Practice: The Example of Dihydropyrimidine Dehydrogenase.

scientific article published on 25 January 2017

Pharmacogenetics of CYP2D6 and tamoxifen therapy: Light at the end of the tunnel?

scientific article published on 6 April 2016

Pharmacogenetics of androgen signaling in prostate cancer: Focus on castration resistance and predictive biomarkers of response to treatment

scientific article published on 6 March 2018

Pharmacokinetic and pharmacogenetic predictive markers of irinotecan activity and toxicity.

scientific article published on December 2011

Phosphorylation of AKT and ERK1/2 and mutations of PIK3CA and PTEN are predictive of breast cancer cell sensitivity to everolimus in vitro

scientific article published on 23 February 2018

Predicting fluoropyrimidine-related toxicity: turning wish to will, the PAMM-EORTC position

article

Prevention of fluoropyrimidine toxicity: do we still have to try our patient's luck?

article

Primary resistance to osimertinib due to SCLC transformation: Issue of T790M determination on liquid re-biopsy

scientific article

Protein kinase inhibitors for the treatment of advanced and progressive radiorefractory thyroid tumors: From the clinical trials to the real life

scientific article

Radiomics and liquid biopsy in oncology: the holons of systems medicine

scientific article published on 14 November 2018

Real-Time PCR and Droplet Digital PCR: two techniques for detection of the JAK2(V617F) mutation in Philadelphia-negative chronic myeloproliferative neoplasms.

scientific article published on 20 July 2015

Recent advances in epigenomics in NSCLC: real-time detection and therapeutic implications

scientific article

Rechallenge for Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer With Acquired Resistance to First-line Cetuximab and Irinotecan: A Phase 2 Single-Arm Clinical Trial

scientific article published on 01 March 2019

Reply to Ugo De Giorgi, Vincenza Conteduca, and Emanuela Scarpi's Letter to the Editor re: Marzia Del Re, Elisa Biasco, Stefania Crucitta, et al. The Detection of Androgen Receptor Splice Variant 7 in Plasma-derived Exosomal RNA Strongly Predicts Re

scientific article published on 9 August 2017

Should CYP2D6 be genotyped when treating with tamoxifen?

scientific article published on 08 June 2017

ShouldCYP2D6be genotyped when treating with tamoxifen?

scientific article published on 24 November 2016

Synergistic interaction between PPAR ligands and salbutamol on human bronchial smooth muscle cell proliferation

scientific article published on January 1, 2013

The Detection of Androgen Receptor Splice Variant 7 in Plasma-derived Exosomal RNA Strongly Predicts Resistance to Hormonal Therapy in Metastatic Prostate Cancer Patients.

scientific article published on 26 August 2016

The Droplet Digital PCR: A New Valid Molecular Approach for the Assessment of B-RAF V600E Mutation in Hairy Cell Leukemia

scientific article

The amount of activating EGFR mutations in circulating cell-free DNA is a marker to monitor osimertinib response

scientific article published on 06 November 2018

The emerging role of liquid biopsy in diagnosis, prognosis and treatment monitoring of pancreatic cancer

scientific article published on 06 December 2018

The increase in activating EGFR mutation in plasma is an early biomarker to monitor response to osimertinib: a case report

scientific article published on 30 April 2019

The role of drug-drug interactions in prostate cancer treatment: Focus on abiraterone acetate/prednisone and enzalutamide

scientific article published on 9 March 2017

Total and not bevacizumab-bound vascular endothelial growth factor as potential predictive factors to bevacizumab-based chemotherapy in colorectal cancer

scientific article published on July 2016

Uncommon dihydropyrimidine dehydrogenase mutations and toxicity by fluoropyrimidines: a lethal case with a new variant.

scientific article published on 14 December 2015

Understanding EGFR heterogeneity in lung cancer

scientific article published on 01 October 2020

Understanding the Mechanisms of Resistance in EGFR-Positive NSCLC: From Tissue to Liquid Biopsy to Guide Treatment Strategy

scientific article published on 14 August 2019

Unusual gastrointestinal and cutaneous toxicities by bleomycin, etoposide, and cisplatin: a case report with pharmacogenetic analysis to personalize treatment.

scientific article published on 7 March 2017

eNOS polymorphisms as predictors of efficacy of bevacizumab-based chemotherapy in metastatic colorectal cancer: data from a randomized clinical trial

scientific article

erbB in NSCLC as a molecular target: current evidences and future directions

scientific article published on 01 August 2020