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List of works by Alexandra K Kiemer

Activation of Rac1 GTPase by nanoparticulate structures in human macrophages.

scientific article published on 18 January 2013

Altered glucocorticoid metabolism represents a feature of macroph-aging

scientific article published on 28 May 2020

Amplified Host Defense by Toll-Like Receptor-Mediated Downregulation of the Glucocorticoid-Induced Leucine Zipper (GILZ) in Macrophages

scientific article published on 01 January 2018

Atrial natriuretic peptide preconditioning protects against hepatic preservation injury by attenuating necrotic and apoptotic cell death

scientific article published in September 2003

Atrial natriuretic peptide reduces expression of TNF-α mRNA during reperfusion of the rat liver upon decreased activation of NF-κB and AP-1

scientific article published on 01 August 2000

Atrial natriuretic peptide, a regulator of nuclear factor-kappaB activation in vivo.

scientific article published on 28 September 2006

Autocrine regulation of inducible nitric-oxide synthase in macrophages by atrial natriuretic peptide

scientific article published on 01 May 1998

Baikalomycins A-C, New Aquayamycin-Type Angucyclines Isolated from Lake Baikal Derived Streptomyces sp. IB201691-2A ⬇️

scientific article published on 07 May 2020

Bcl-2 upregulation after 3-nitropropionic acid preconditioning in warm rat liver ischemia

scientific article published in December 2008

Characterization of heme oxygenase 1 (heat shock protein 32) induction by atrial natriuretic peptide in human endothelial cells.

scientific article published in March 2003

Different protection mechanisms after pretreatment with glycine or alpha-lipoic acid in a rat model of warm hepatic ischemia

scientific article published on 04 October 2006

Differential cell reaction upon Toll-like receptor 4 and 9 activation in human alveolar and lung interstitial macrophages.

scientific article

Discovery and optimization of 1,3,5-trisubstituted pyrazolines as potent and highly selective allosteric inhibitors of protein kinase C-ζ

scientific article (publication date: 14 August 2014)

Downregulation of the glucocorticoid-induced leucine zipper (GILZ) promotes vascular inflammation

scientific article published on 5 April 2014

Effect of allicin and ajoene, two compounds of garlic, on inducible nitric oxide synthase.

scientific article published on August 1998

Elevated free cholesterol in a p62 overexpression model of non-alcoholic steatohepatitis.

scientific article

Exploring synthetic avenues for the effective synthesis of selenium- and tellurium-containing multifunctional redox agents.

scientific article published on 11 September 2009

Fatty acid elongation in non-alcoholic steatohepatitis and hepatocellular carcinoma

scientific article published on 4 April 2014

Glucocorticoid-induced leucine zipper is downregulated in human alveolar macrophages upon Toll-like receptor activation.

scientific article

Glucocorticoid-induced leucine zipper: a critical factor in macrophage endotoxin tolerance.

scientific article published on 11 May 2015

Hepatic hepcidin expression is decreased in cirrhosis and HCC

scientific article published on 21 November 2014

Hepatic interleukin-6 production is maintained during endotoxin tolerance and facilitates lipid accumulation

scientific article

Hepatocellular Carcinoma and Nuclear Paraspeckles: Induction in Chemoresistance and Prediction for Poor Survival

scientific article published on 01 January 2019

Hepatocellular Injury of Nonischemic Liver Tissue after Selective Clamping in Rats – Protective Action by Pharmacological Pretreatment with Lipoic Acid

scientific article published on 02 July 2007

High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype

scientific article published on 12 November 2018

Hsp72 protects from liver injury via attenuation of hepatocellular death, oxidative stress and JNK-signaling.

scientific article published on 10 January 2018

IGF2 mRNA binding protein p62/IMP2-2 in hepatocellular carcinoma: antiapoptotic action is independent of IGF2/PI3K signaling

scientific article published on 20 December 2012

IMP2/IGF2BP2 expression, but not IMP1 and IMP3, predicts poor outcome in patients and high tumor growth rate in xenograft models of gallbladder cancer.

scientific article

IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype.

scientific article

In vivo regulation of inducible no synthase in immune-mediated liver injury in mice

scientific article published on 01 November 2002

Induction of Glucocorticoid-induced Leucine Zipper (GILZ) Contributes to Anti-inflammatory Effects of the Natural Product Curcumin in Macrophages.

scientific article

Induction of IκB: atrial natriuretic peptide as a regulator of the NF-κB pathway

scientific article published on 01 August 2002

Inflammation-induced up-regulation of TLR2 expression in human endothelial cells is independent of differential methylation in the TLR2 promoter CpG island.

scientific article

Inhibition of LPS-induced nitric oxide and TNF-alpha production by alpha-lipoic acid in rat Kupffer cells and in RAW 264.7 murine macrophages

scientific article

Inhibition of cyclooxygenase-2 by natriuretic peptides

scientific article published in March 2002

Inhibition of p38 MAPK activation via induction of MKP-1: atrial natriuretic peptide reduces TNF-alpha-induced actin polymerization and endothelial permeability

scientific article published in May 2002

Inhibitory effects of teuclatriol, a sesquiterpene from salvia mirzayanii, on nuclear factor-κB activation and expression of inflammatory mediators

scientific article

Insulin-Like Growth Factor 2 - The Oncogene and its Accomplices.

scientific article

Kupffer-cell specific induction of heme oxygenase 1 (hsp32) by the atrial natriuretic peptide--role of cGMP.

scientific article published in April 2003

Lack of Kupffer cell depletion in diethylnitrosamine-induced hepatic inflammation

scientific article published on 24 January 2019

Lipid Metabolism Signatures in NASH-Associated HCC--Letter

scientific article published on 28 April 2014

Lipid droplets as a novel cargo of tunnelling nanotubes in endothelial cells.

scientific article

M2 polarization enhances silica nanoparticle uptake by macrophages

scientific article

MAPK phosphatase-1 represents a novel anti-inflammatory target of glucocorticoids in the human endothelium.

scientific article

Myxobacteria-Derived Outer Membrane Vesicles: Potential Applicability Against Intracellular Infections

scientific article published on 12 January 2020

Nanostructured Microparticles Repolarize Macrophages and Induce Cell Death in an In Vitro Model of Tumour-Associated Macrophages

scientific article published in 2023

Non-invasive live-cell measurement of changes in macrophage NAD(P)H by two-photon microscopy.

scientific article

Nuclear factor-kappa B-independent anti-inflammatory action of salicylate in human endothelial cells: induction of heme oxygenase-1 by the c-jun N-terminal kinase/activator protein-1 pathway

scientific article (publication date: July 2006)

Parenchymal, But Not Leukocyte, TNF Receptor 2 Mediates T Cell-Dependent Hepatitis in Mice

scientific article published on 01 February 2003

Pharmacological inhibition of protein kinase C (PKC)ζ downregulates the expression of cytokines involved in the pathogenesis of chronic obstructive pulmonary disease (COPD).

scientific article published on 8 August 2016

Phyllanthus amarus has anti-inflammatory potential by inhibition of iNOS, COX-2, and cytokines via the NF-kappaB pathway

scientific article published in March 2003

Protection from hepatic ischemia/reperfusion injury and improvement of liver regeneration by alpha-lipoic acid

scientific article published on 01 June 2007

Protein kinase A dependent signalling mediates anti-apoptotic effects of the atrial natriuretic peptide in ischemic livers.

scientific article published in September 2004

Rapid chromatographic method to decipher distinct alterations in lipid classes in NAFLD/NASH.

scientific article published on October 2013

Silibinin protects mice from T cell-dependent liver injury

scientific article published in September 2003

Small BODIPY Probes for Combined Dual (19) F MRI and Fluorescence Imaging

scientific article published on 27 June 2016

Superparamagnetic iron oxide nanoparticles impair endothelial integrity and inhibit nitric oxide production.

scientific article published on 11 August 2014

Susceptibility of Different Mouse Wild Type Strains to Develop Diet-Induced NAFLD/AFLD-Associated Liver Disease

scientific article

Targeted delivery of functionalized PLGA nanoparticles to macrophages by complexation with the yeast Saccharomyces cerevisiae

scientific article published on 28 November 2019

The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis.

scientific article

The atrial natriuretic peptide as a regulator of Kupffer cell functions

scientific article published in May 2002

The insulin-like growth factor 2 (IGF2) mRNA-binding protein p62/IGF2BP2-2 as a promoter of NAFLD and HCC?

scientific article published on 30 October 2013

The mRNA-binding Protein TTP/ZFP36 in Hepatocarcinogenesis and Hepatocellular Carcinoma

scientific article published on 08 November 2019

Thioholgamide A, a New Anti-Proliferative Anti-Tumor Agent, Modulates Macrophage Polarization and Metabolism

scientific article published on 19 May 2020

Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation.

scientific article published on 25 April 2016

Vasoprotective actions of the atrial natriuretic peptide.

scientific article

Yeast (Saccharomyces cerevisiae) Polarizes Both M-CSF- and GM-CSF-Differentiated Macrophages Toward an M1-Like Phenotype.

scientific article published on 15 July 2016

Yeast-mediated mRNA delivery polarizes immuno-suppressive macrophages towards an immuno-stimulatory phenotype

scientific article published on 17 March 2017

cGMP-Mediated Inhibition of TNF- Production by the Atrial Natriuretic Peptide in Murine Macrophages

article

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