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List of works by Geoffrey J. Lindeman

11th Lorne Cancer Conference, Lorne, Victoria, Australia, 11-14th February 1999.

scientific article

A Phase Ib Dose-Escalation and Expansion Study of the BCL2 Inhibitor Venetoclax Combined with Tamoxifen in ER and BCL2-Positive Metastatic Breast Cancer

scientific article published on 05 December 2018

A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1.

scientific article

A role for common genomic variants in the assessment of familial breast cancer

scientific article published on 29 October 2012

A single-cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast

scientific article published on 05 May 2021

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

scientific article published on 2 August 2009

Abstract 1130: First-in-class KAT6A/KAT6B inhibitor CTx-648 (PF-9363) demonstrates potent anti-tumor activity in ER+ breast cancer with KAT6A dysregulation

scientific article published in 2021

Accuracy and completeness in reporting family history of prostate cancer by unaffected men.

scientific article

Aldehyde dehydrogenase activity is a biomarker of primitive normal human mammary luminal cells.

scientific article published in February 2012

An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

scientific article

Analysis of Brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit

scientific article published on 6 December 2010

Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients

scientific article published on 04 November 2011

Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab familial breast cancer resource

scientific article

BARD1 variants are not associated with breast cancer risk in Australian familial breast cancer

article

Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer

scientific article published in Nature Communications

Bfk: a novel weakly proapoptotic member of the Bcl-2 protein family with a BH3 and a BH2 region.

scientific article published on February 2003

Breast cancer prevention for BRCA1 and BRCA2 mutation carriers: is there a role for tamoxifen?

scientific article

Breast cancer protein StarD10 identified by three-dimensional separation using free-flow electrophoresis, reversed-phase high-performance liquid chromatography, and sodium dodecyl sulfate-polyacrylamide gel electrophoresis

article

Breast cancer risk and the BRCA1 interacting protein CTIP

scientific article published on 20 December 2007

Breast conservation versus mastectomy in triple-negative breast cancer: two steps forward, one step back?

scientific article published on 31 October 2011

Breast-Cancer Risk in Families With Mutations in PALB2

Breast-cancer risk in families with mutations in PALB2

scientific article

CPAP interacts with 14-3-3 in a cell cycle-dependent manner

scientific journal article

CPAP is a novel stat5-interacting cofactor that augments stat5-mediated transcriptional activity

scientific article (publication date: September 2002)

Cancer risk management practices of noncarriers within BRCA1/2 mutation positive families in the Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer

scientific article published on 26 November 2007

Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

scientific article

Cancer stem cells: current status and evolving complexities

scientific article published on June 2012

Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids

scientific article published on 06 August 2018

Cell fate takes a slug in BRCA1-associated breast cancer ⬇️

scientific article published on April 6, 2011

Challenges to the Development of New Agents for Molecularly Defined Patient Subsets: Lessons FromBRCA1/2-Associated Breast Cancer

article

Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancer

scientific article

Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer

scientific article published in Nature Communications

Complete radiological and metabolic response of metastatic renal cell carcinoma to SU5416 (semaxanib) in a patient with probable von Hippel-Lindau syndrome

scientific article

Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling.

scientific article published on 20 November 2017

Control of mammary stem cell function by steroid hormone signalling.

scientific article published on 11 April 2010

Deaf-1 regulates epithelial cell proliferation and side-branching in the mammary gland

scientific article

Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1

scientific journal article

Delineating the epithelial hierarchy in the mouse mammary gland.

scientific article

Derivation of a robust mouse mammary organoid system for studying tissue dynamics

scientific article

Differential hypermethylation of SOCS genes in ovarian and breast carcinomas.

scientific article

Dimerization of CtIP, a BRCA1- and CtBP-interacting protein, is mediated by an N-terminal coiled-coil motif

scientific article published on 14 April 2004

Distinct nuclear receptor expression in stroma adjacent to breast tumors.

scientific article

Dual roles for Id4 in the regulation of estrogen signaling in the mammary gland and ovary.

scientific article published on 18 July 2014

Dual targeting of CDK4/6 and BCL2 pathways augments tumor response in estrogen receptor positive breast cancer

scientific article published on 03 April 2020

E2F4 is exported from the nucleus in a CRM1-dependent manner.

scientific article

EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival

scientific article

Elf5 is essential for early embryogenesis and mammary gland development during pregnancy and lactation

scientific article

Essential role for a novel population of binucleated mammary epithelial cells in lactation.

scientific article

Experiences and interpretations of BRCA1/2 testing among women affected by breast or ovarian cancer who received a negative result

scientific article published on 27 March 2019

Expression of S100A2 calcium-binding protein predicts response to pancreatectomy for pancreatic cancer

scientific article published on 16 April 2009

Familial cancer 2003 - research and practice, Couran Cove, Queensland, Australia, 3-6 September 2003.

scientific article published on January 2004

Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence

scientific article published on 25 October 2018

Frequency of the ATM IVS10-6T-->G variant in Australian multiple-case breast cancer families

scientific article

Frequent activating STAT3 mutations and novel recurrent genomic abnormalities detected in breast implant-associated anaplastic large cell lymphoma

article

Frequent somatic mutations of GATA3 in non-BRCA1/BRCA2 familial breast tumors, but not in BRCA1-, BRCA2- or sporadic breast tumors

scientific article published on 3 February 2009

Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

scientific article

Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14.

scientific article published on 19 September 2011

Gene methylation in breast ductal fluid from BRCA1 and BRCA2 mutation carriers.

scientific article

Generation of a functional mammary gland from a single stem cell

scientific article (publication date: 5 January 2006)

Genetic services for men: the preferences of men with a family history of prostate cancer

scientific article published on 01 December 2006

Genetic, functional, and histopathological evaluation of two C-terminal BRCA1 missense variants

scientific article published on 27 May 2005

Germline BRCA1 promoter deletions in UK and Australian familial breast cancer patients: Identification of a novel deletion consistent with BRCA1:psiBRCA1 recombination.

scientific article published on April 2002

Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2.

scientific article

Grhl3 and Lmo4 play coordinate roles in epidermal migration

scientific article published on 26 June 2008

Hereditary breast cancer genetics--from clinical curiosities to mainstream paradigms

scientific article published in April 2011

Identification of Taxreb107 as a lactogenic hormone responsive gene in mammary epithelial cells

scientific article published on October 2003

Identification of quiescent and spatially restricted mammary stem cells that are hormone responsive.

scientific article

Impaired lactation in mice expressing dominant-negative FADD in mammary epithelium

scientific article published in April 2009

In situ identification of bipotent stem cells in the mammary gland.

scientific article published on 26 January 2014

Inhibition of RANK signaling in breast cancer induces an anti-tumor immune response orchestrated by CD8+ T cells

scientific article published on 10 December 2020

Iniparib administered weekly or twice-weekly in combination with gemcitabine/carboplatin in patients with metastatic triple-negative breast cancer: a phase II randomized open-label study with pharmacokinetics

scientific article published on 06 June 2019

Insights into the cell of origin in breast cancer and breast cancer stem cells

scientific article published on June 2010

Integration of microRNA signatures of distinct mammary epithelial cell types with their gene expression and epigenetic portraits

scientific article published on 18 June 2015

Interim Results from the IMPACT Study: Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers

scientific article published on 16 September 2019

Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging

scientific article published on 01 June 2019

Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging

scientific article published on 28 March 2019

Intravenous or oral adjuvant CMF for node-positive breast cancer

scientific article published on 01 July 1992

Investigation of the transcriptional changes underlying functional defects in the mammary glands of prolactin receptor knockout mice

scientific article

Isolation of mouse mammary epithelial subpopulations: a comparison of leading methods

scientific article published on 30 May 2012

Jekyll or Hyde: does Matrigel provide a more or less physiological environment in mammary repopulating assays?

scientific article published on 25 May 2011

Knocking off SOCS genes in the mammary gland.

scientific article published on 20 April 2007

LMO4 expression in squamous cell carcinoma of the anterior tongue.

scientific article

Large genomic rearrangements in the familial breast and ovarian cancer gene BRCA1 are associated with an increased frequency of high risk features

scientific article published on June 2015

Lineage enforcement by inductive mesenchyme on adult epithelial stem cells across developmental germ layers

scientific article

Loss of STARD10 expression identifies a group of poor prognosis breast cancers independent of HER2/Neu and triple negative status.

scientific article

Loss of the LIM domain protein Lmo4 in the mammary gland during pregnancy impedes lobuloalveolar development

scientific article published in July 2005

MMTV-trBrca1 mice display strain-dependent abnormalities in vaginal development

scientific article published in September 2004

Macrophages, more than just scavengers: their role in breast development and cancer.

scientific article published on June 2008

Mainstreaming cancer genetics: A model integrating germline BRCA testing into routine ovarian cancer clinics

scientific article

Mammary stem cells and mammopoiesis

scientific article published on October 2006

Mammary stem cells and their regulation by steroid hormones

scientific article published on 01 May 2011

Management of testicular seminoma at Westmead Hospital from 1980 to 87

scientific article published on 01 March 1991

Modeling breast cancer using CRISPR/Cas9-mediated engineering of human breast organoids

scientific article published on 07 October 2019

Mutation analysis of FANCD2, BRIP1/BACH1, LMO4 and SFN in familial breast cancer

scientific article

Mutational analysis of the LMO4 gene, encoding a BRCA1-interacting protein, in breast carcinomas

scientific article (publication date: 20 October 2003)

New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells

scientific article

Nipple aspiration and ductal lavage in women with a germline BRCA1 or BRCA2 mutation

scientific article

Notch signaling regulates mammary stem cell function and luminal cell-fate commitment.

scientific article published in October 2008

Novel p53 germline mutation in a patient with Li-Fraumeni syndrome.

scientific article

Out-RANKing BRCA1 in Mutation Carriers.

scientific article published on 19 January 2017

Outcomes of women at high familial risk for breast cancer: An 8-year single-center experience

scientific article published on 28 October 2019

Overexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancer

scientific article

Patient and medical barriers preclude uptake of tamoxifen preventative therapy in women with a strong family history.

scientific article published on 17 January 2017

Patient-derived xenograft (PDX) models in basic and translational breast cancer research.

scientific article published on 27 December 2016

Patient-derived xenograft models of breast cancer and their predictive power

scientific article

Phase 1 trial of olaparib and oral cyclophosphamide in BRCA breast cancer, recurrent BRCA ovarian cancer, non-BRCA triple-negative breast cancer, and non-BRCA ovarian cancer

scientific article published on 17 January 2019

Phase I trial of the oral PARP inhibitor olaparib in combination with paclitaxel for first- or second-line treatment of patients with metastatic triple-negative breast cancer.

scientific article published on January 2013

Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors

scientific article published on 12 March 2021

Predictors of long-term cancer-related distress among female BRCA1 and BRCA2 mutation carriers without a cancer diagnosis: an international analysis

scientific article published on 12 May 2020

Predictors of participation in clinical and psychosocial follow-up of the kConFab breast cancer family cohort

scientific article published on January 2005

Predictors of the use of complementary and alternative medicine (CAM) by women at high risk for breast cancer

scientific article published on 7 November 2008

Preferences for breast cancer prevention among women with a BRCA1 or BRCA2 mutation

scientific article published on 29 September 2020

Preferences for breast cancer risk reduction among BRCA1/BRCA2 mutation carriers: a discrete-choice experiment

scientific article published on 17 June 2017

Pro-apoptotic Bim suppresses breast tumor cell metastasis and is a target gene of SNAI2

article

Prostate screening uptake in Australian BRCA1 and BRCA2 carriers

scientific article published on 15 September 2007

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition

scientific article published on 4 January 2018

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition.

scientific article

Proteomic profiling of secretome and adherent plasma membranes from distinct mammary epithelial cell subpopulations.

scientific article

Publisher Correction: Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer

scientific article published on 24 April 2019

R code and downstream analysis objects for the scRNA-seq atlas of normal and tumorigenic human breast tissue

publication published on 23 March 2022

RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers.

scientific article published on 20 June 2016

RE: Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

scientific article published on 4 April 2017

Resident macrophages influence stem cell activity in the mammary gland

scientific article published on 26 August 2009

Risk-reducing surgery, screening and chemoprevention practices of BRCA1 and BRCA2 mutation carriers: a prospective cohort study

scientific article published in September 2006

Role of Engrailed-2 (EN2) as a prostate cancer detection biomarker in genetically high risk men.

scientific article published in January 2013

Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737

scientific article published on 18 July 2011

Shedding light on mammary stem cells and tumorigenesis

scientific article

Single cell transcriptome atlas of mouse mammary epithelial cells across development

scientific article published on 29 June 2021

Socs2 and elf5 mediate prolactin-induced mammary gland development

scientific journal article

Solitary pituitary metastasis from HER2-positive breast cancer

scientific article published on 14 April 2015

Spotlight on the utility of the Oncotype DX® breast cancer assay.

scientific article published on 21 February 2018

StarD10, a START domain protein overexpressed in breast cancer, functions as a phospholipid transfer protein.

scientific article

Stem Cells and the Differentiation Hierarchy in Mammary Gland Development

scientific article published on 20 September 2019

Stem cells and cancer - the promise and puzzles

scientific article published on 27 July 2010

Steroid hormone receptor status of mouse mammary stem cells

scientific article

Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer

scientific article published in August 2017

Tailored NEOadjuvant epirubicin, cyclophosphamide and Nanoparticle Albumin-Bound paclitaxel for breast cancer: The phase II NEONAB trial-Clinical outcomes and molecular determinants of response

scientific article published on 14 February 2019

Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study

scientific article

Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 detects aggressive prostate cancer: preliminary analysis of the results of the IMPACT study

scientific article published on 14 September 2010

Targeting BCL-2 to enhance vulnerability to therapy in estrogen receptor-positive breast cancer.

scientific article published on 10 August 2015

Targeting BCL-2 with the BH3 mimetic ABT-199 in estrogen receptor-positive breast cancer

scientific article

Targeting triple-negative breast cancers with the Smac-mimetic birinapant

scientific article published on 27 April 2020

The Angelina Jolie effect

scientific article published in November 2013

The Ets transcription factor Elf5 specifies mammary alveolar cell fate

scientific article

The LIM domain gene LMO4 inhibits differentiation of mammary epithelial cells in vitro and is overexpressed in breast cancer.

scientific article

The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity

scientific article

The LIM domain protein Lmo4 is highly expressed in proliferating mouse epithelial tissues

scientific article published on April 2005

The beliefs, and reported and intended behaviors of unaffected men in response to their family history of prostate cancer

scientific article published on June 2008

The complexities and caveats of lineage tracing in the mammary gland.

scientific article published on 25 November 2016

The emerging picture of the mouse mammary stem cell

scientific article published on June 2007

The future of mammary stem cell biology: the power of in vivo transplants

scientific article published on 29 May 2008

The incidence of PALB2 c.3113G>A in women with a strong family history of breast and ovarian cancer attending familial cancer centres in Australia.

scientific article

The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis

scientific article published on 01 October 2008

The mammary stem cell hierarchy.

scientific article published on January 2014

The molecular culprits underlying precocious mammary gland involution

scientific article published on March 2007

The phosphoprotein StarD10 is overexpressed in breast cancer and cooperates with ErbB receptors in cellular transformation

scientific article published on May 2004

The role of bipedal lymphangiography in testicular seminoma

scientific article published on 01 November 1990

The role of poly adenosine diphosphate ribose polymerase inhibitors in breast and ovarian cancer: current status and future directions

scientific article published on September 2011

The rs10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urine

scientific article published in 2010

The unmasking of novel unipotent stem cells in the mammary gland

scientific article published on 8 November 2011

Threonine 391 phosphorylation of the human prolactin receptor mediates a novel interaction with 14-3-3 proteins

scientific article

Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling

scientific article published on 27 April 2020

Towards more effective and equitable genetic testing for BRCA1 and BRCA2 mutation carriers

scientific article published on 01 November 2008

Transcriptional regulators in mammary gland development and cancer

scientific article

Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways

scientific article

Triple-negative breast cancer: making the most of a misnomer

scientific article published on June 2012

Two promoters within the human LMO4 gene contribute to its overexpression in breast cancer cells

scientific article published on September 2003

XIAP-deficiency leads to delayed lobuloalveolar development in the mammary gland.

scientific article published in January 2005

c-myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3.

scientific article

“Cancer in the family” and genetic testing: implications for life insurance ⬇️

scientific article published on November 3, 2003

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