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List of works by Ygal Haupt

A Role for the Polyproline Domain of p53 in Its Regulation by Mdm2

scientific article published in Journal of Biological Chemistry

AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy.

scientific article published on 12 September 2011

APR-246 potently inhibits tumour growth and overcomes chemoresistance in preclinical models of oesophageal adenocarcinoma

scientific article published on 17 July 2015

An Analysis of a Multiple Biomarker Panel to Better Predict Prostate Cancer Metastasis After Radical Prostatectomy

scientific article published on 04 December 2018

Biodosimetric transcriptional and proteomic changes are conserved in irradiated human tissue

scientific article published on 30 May 2018

Clioquinol induces cytoplasmic clearance of the X-linked inhibitor of apoptosis protein (XIAP): therapeutic indication for prostate cancer.

scientific article published on June 2011

Co-targeting deoxyribonucleic acid-dependent protein kinase and poly(adenosine diphosphate-ribose) polymerase-1 promotes accelerated senescence of irradiated cancer cells

scientific article published on February 2014

E6AP ubiquitin ligase regulates PML-induced senescence in Myc-driven lymphomagenesis

scientific article published on 11 June 2012

Editorial: Human Tumor-Derived p53 Mutants: A Growing Family of Oncoproteins

scientific article published on 12 July 2016

Exploring the oncoproteomic response of human prostate cancer to therapeutic radiation using data-independent acquisition (DIA) mass spectrometry

scientific article published on 09 March 2018

Facilitation of adenoviral wild-type p53-induced apoptotic cell death by overexpression of p33(ING1) in T.Tn human esophageal carcinoma cells

scientific article

Flow Cytometric Analysis of p53-Induced Apoptosis

scientific article published on 01 January 2003

HPV16 E6 and E6AP differentially cooperate to stimulate or augment Wnt signaling.

scientific article published on 28 September 2014

HPV16 E6 augments Wnt signaling in an E6AP-dependent manner

scientific article published on 06 November 2009

Hhex induces promyelocyte self-renewal and cooperates with growth factor independence to cause myeloid leukemia in mice

scientific article published on 01 February 2018

Increasing intracellular bioavailable copper selectively targets prostate cancer cells

scientific article published on 24 May 2013

Inhibiting the system xC-/glutathione axis selectively targets cancers with mutant-p53 accumulation

scientific article published on 28 March 2017

Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis

scientific article published on September 2017

MDM4 is a key therapeutic target in cutaneous melanoma

scientific article published on 22 July 2012

MDM4 is a rational target for treating breast cancers with mutant p53.

scientific article published on 18 January 2017

Moloney virus induction of T-cell lymphomas in a plasmacytomagenic strain of E mu-v-abl transgenic mice.

scientific article published in October 1993

Mutant p53 subverts PLK2 function in a novel, reinforced loop of corruption ⬇️

scientific article published on January 15, 2012

Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice.

scientific article published in May 1991

Reduced abundance of the E3 ubiquitin ligase E6AP contributes to decreased expression of the INK4/ARF locus in non-small cell lung cancer

scientific article published on 10 January 2017

Role of p53 in the progression of gastric cancer

scientific article published on December 2014

Stimulating p53 down-under: a report from the 1st Australian p53 Workshop

scientific article published on February 2013

T cell survival and function requires the c-Abl tyrosine kinase

scientific article

TP53 Status, Patient Sex, and the Immune Response as Determinants of Lung Cancer Patient Survival

scientific article published on 11 June 2020

The E3-ligase E6AP Represses Breast Cancer Metastasis via Regulation of ECT2-Rho Signaling

scientific article published on 26 May 2016

The Mdm2 oncoprotein interacts with the cell fate regulator Numb

scientific article

The Transcriptional Landscape of Radiation-Treated Human Prostate Cancer: Analysis of a Prospective Tissue Cohort.

scientific article published on 25 September 2017

The promyelocytic leukemia protein protects p53 from Mdm2-mediated inhibition and degradation

scientific article

Transactivation-deficient p73alpha (p73Deltaexon2) inhibits apoptosis and competes with p53.

scientific article published on January 2001

Ubiquitin ligase E6AP mediates nonproteolytic polyubiquitylation of β-catenin independent of the E6 oncoprotein

scientific article published on 7 October 2016

c-Abl phosphorylates Hdmx and regulates its interaction with p53.

scientific article

c-Jun and p53 Activity Is Modulated by SUMO-1 Modification

scientific article published in Journal of Biological Chemistry

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