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List of works by Javier Lopez-Rios

Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs

scientific article published on 18 June 2014

Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease

scientific article published on March 2008

Conserved cis-regulatory regions in a large genomic landscape control SHH and BMP-regulated Gremlin1 expression in mouse limb buds

scientific article

Dual RMCE for efficient re-engineering of mouse mutant alleles

scientific article

Enhancer redundancy provides phenotypic robustness in mammalian development

scientific article published on 31 January 2018

GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis

scientific article published on 29 March 2012

Genomic cloning and characterization of the human homeobox gene SIX6 reveals a cluster of SIX genes in chromosome 14 and associates SIX6 hemizygosity with bilateral anophthalmia and pituitary anomalies

scientific article

Genomic cloning, structure, expression pattern, and chromosomal location of the human SIX3 gene.

scientific article

HAND2 Target Gene Regulatory Networks Control Atrioventricular Canal and Cardiac Valve Development

scientific article published on May 2017

HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme

scientific article

Hand2 is an essential regulator for two Notch-dependent functions within the embryonic endocardium

scientific article published on 11 December 2014

Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development

scientific article

Progressive Loss of Function in a Limb Enhancer during Snake Evolution

scientific article published on October 2016

Recapitulation of endochondral bone formation using human adult mesenchymal stem cells as a paradigm for developmental engineering

scientific article

SFRP1 is required for the proper establishment of the eye field in the medaka fish

scientific article published in July 2004

Sensing BMP pathway activity by immune detection of phosphorylated R-Smad proteins in mouse embryonic kidney.

scientific article published in January 2012

Six3 and Six6 activity is modulated by members of the groucho family

scientific article

Six9 (Optx2), a new member of the six gene family of transcription factors, is expressed at early stages of vertebrate ocular and pituitary development

scientific article

The Netrin-related domain of Sfrp1 interacts with Wnt ligands and antagonizes their activity in the anterior neural plate

scientific article

The many lives of SHH in limb development and evolution

scientific article

Ultraconserved non-coding sequence element controls a subset of spatiotemporal GLI3 expression

scientific article

Vertebrate limb bud development: moving towards integrative analysis of organogenesis

scientific article