List of works by Xavier Rovira

A Light-Controlled Allosteric Modulator Unveils a Role for mGlu Receptors During Early Stages of Ischemia in the Rodent Cerebellar Cortex

scientific article published on 27 November 2018

Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer.

scientific article

Allosteric modulation of metabotropic glutamate receptors by chloride ions

scientific article

Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation.

scientific article published on 6 December 2017

An allosteric modulator to control endogenous G protein-coupled receptors with light.

scientific article published on 31 August 2014

Assessing receptor affinity for inverse agonists: Schild and Cheng-Prusoff methods revisited.

scientific article published on January 2007

Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3

scientific article published on 11 August 2018

Correction: Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator

scientific article

Defective signaling through plexin-A1 compromises the development of the peripheral olfactory system and neuroendocrine reproductive axis in mice

scientific article published on 2 March 2017

Dynamic modulation of inflammatory pain-related affective and sensory symptoms by optical control of amygdala metabotropic glutamate receptor 4.

scientific article published on 20 December 2016

Exploring the Active Conformation of Cyclohexane Carboxylate Positive Allosteric Modulators of the Type 4 Metabotropic Glutamate Receptor

scientific article published on 05 September 2014

FRET-Based Sensors Unravel Activation and Allosteric Modulation of the GABAB Receptor

scientific article published on 6 March 2017

Illuminating Phenylazopyridines To Photoswitch Metabotropic Glutamate Receptors: From the Flask to the Animals

scientific article published on 19 December 2016

Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer.

scientific article published on 15 December 2014

Modeling the binding and function of metabotropic glutamate receptors.

scientific article published on 20 February 2008

Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator

scientific article published on 11 April 2017

OptoGluNAM4.1, a Photoswitchable Allosteric Antagonist for Real-Time Control of mGlu4 Receptor Activity.

scientific article published on 27 July 2016

Overlapping binding sites drive allosteric agonism and positive cooperativity in type 4 metabotropic glutamate receptors

scientific article published on 23 October 2014

Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells

scientific article

Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu5 negative allosteric modulation.

scientific article published on 12 January 2017

Rearrangement of the transmembrane domain interfaces associated with the activation of a GPCR hetero-oligomer

scientific article published on 24 June 2019

Shedding light on metabotropic glutamate receptors using optogenetics and photopharmacology

scientific article published on 15 February 2018

Shining Light on an mGlu5 Photoswitchable NAM: A Theoretical Perspective

scientific article published on 7 April 2015

The asymmetric/symmetric activation of GPCR dimers as a possible mechanistic rationale for multiple signalling pathways.

scientific article published on 04 December 2009

The catalytic power of enzymes: conformational selection or transition state stabilization?

scientific article published on 30 March 2006

The role of residue stability in transient protein-protein interactions involved in enzymatic phosphate hydrolysis. A computational study

scientific article published in April 2006

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