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List of works by Sabine Mai

3D Telomere FISH defines LMP1-expressing Reed–Sternberg cells as end-stage cells with telomere-poor ‘ghost’ nuclei and very short telomeres

scientific article published on 08 February 2010

3D Telomeric Fingerprint of Mycosis Fungoides/ Sézary Syndrome: A Pilot Study

scientific article published on 16 November 2020

3D imaging of telomeres and nuclear architecture: An emerging tool of 3D nano-morphology-based diagnosis

scientific article

3D nuclear organization and genomic instability in cancer

scientific article published on 4 April 2013

3D nuclear organization of telomeres in the Hodgkin cell lines U-HO1 and U-HO1-PTPN1: PTPN1 expression prevents the formation of very short telomeres including "t-stumps".

scientific article published on 14 December 2010

3D structural and functional characterization of the transition from Hodgkin to Reed-Sternberg cells.

scientific article published on 06 August 2010

A new der(1;7)(q10;p10) leading to a singular 1p loss in a case of glioblastoma with oligodendroglioma component

scientific article published on 30 September 2013

Advancing Risk Assessment of Intermediate Risk Prostate Cancer Patients

scientific article published on 20 June 2019

Alterations of centromere positions in nuclei of immortalized and malignant mouse lymphocytes

scientific article published in June 2007

Aqueous mounting media increasing tissue translucence improve image quality in Structured Illumination Microscopy of thick biological specimen

scientific article published in Scientific Reports

Assessment of the clinical relevance of 17q25.3 copy number and three-dimensional telomere organization in non-small lung cancer patients

scientific article published on 30 November 2015

Binding of multivalent CD147 phage induces apoptosis of U937 cells.

scientific article published on June 2006

C-myc overexpression facilitates radiation-induced DHFR gene amplification

article

Cell cycle-dependent 3D distribution of telomeres and telomere repeat-binding factor 2 (TRF2) in HaCaT and HaCaT-myc cells.

scientific article published on December 2004

Centromeres in cell division, evolution, nuclear organization and disease.

scientific article published on August 2008

Changes in Nuclear Orientation Patterns of Chromosome 11 during Mouse Plasmacytoma Development

scientific article

Characterizing the three-dimensional organization of telomeres in papillary thyroid carcinoma cells

scientific article published on 17 October 2018

Characterizing the three-dimensional organization of telomeres.

scientific article

Choices for tissue visualization with IR microspectroscopy

scholarly article by Kathleen Gough et al published July 2005 in Vibrational Spectroscopy

Chromosomal rearrangements after ex vivo Epstein–Barr virus (EBV) infection of human B cells

scientific article published on 02 November 2009

Circulating Tumor Cells (CTC) and Cell-Free DNA (cfDNA) Workshop 2016: Scientific Opportunities and Logistics for Cancer Clinical Trial Incorporation

scientific article published on 8 September 2016

Cyclin E amplification/overexpression is a mechanism of trastuzumab resistance in HER2+ breast cancer patients

scientific article

DNA Superresolution Structure of Reed-Sternberg Cells Differs Between Long-Lasting Remission Versus Relapsing Hodgkin's Lymphoma Patients

scientific article published on 7 December 2015

DNA methylation screening of primary prostate tumors identifies SRD5A2 and CYP11A1 as candidate markers for assessing risk of biochemical recurrence.

scientific article published on September 2015

Dense-core and diffuse Abeta plaques in TgCRND8 mice studied with synchrotron FTIR microspectroscopy

scientific article published in November 2007

Depletion of Trichoplein (TpMs) Causes Chromosome Mis-Segregation, DNA Damage and Chromosome Instability in Cancer Cells

scientific article published on 17 April 2020

Deregulated expression of c-Myc in a translocation-negative plasmacytoma on extrachromosomal elements that carry IgH and myc genes.

scientific article published on November 1999

Differences in nuclear DNA organization between lymphocytes, Hodgkin and Reed-Sternberg cells revealed by structured illumination microscopy

scientific article published on August 2014

Differential nuclear organization of translocation-prone genes in nonmalignant B cells from patients with t(14;16) as compared with t(4;14) or t(11;14) myeloma

scientific article

Differential positioning and close spatial proximity of translocation-prone genes in nonmalignant B-cells from multiple myeloma patients.

scientific article

Disruption of direct 3D telomere-TRF2 interaction through two molecularly disparate mechanisms is a hallmark of primary Hodgkin and Reed-Sternberg cells

scientific article

Distinct 3D Structural Patterns of Lamin A/C Expression in Hodgkin and Reed-Sternberg Cells

Distinct and shared three-dimensional chromosome organization patterns in lymphocytes, monoclonal gammopathy of undetermined significance and multiple myeloma

scientific article

Distinct nuclear orientation patterns for mouse chromosome 11 in normal B lymphocytes

scientific article

Duplication of Subcytoband 11E2 of Chromosome 11 Is Regularly Associated with Accelerated Tumor Development in v-abl/myc-Induced Mouse Plasmacytomas.

scientific article

Dynamic chromosomal rearrangements in Hodgkin's lymphoma are due to ongoing three-dimensional nuclear remodeling and breakage-bridge-fusion cycles

scientific article published on 7 September 2010

Dynamics of three-dimensional telomere profiles of circulating tumor cells in patients with high-risk prostate cancer who are undergoing androgen deprivation and radiation therapies

scientific article published on 9 December 2016

EGF receptor inhibitors in the treatment of glioblastoma multiform: old clinical allies and newly emerging therapeutic concepts.

scientific article published on 18 October 2009

Elongated mouse chromosomes suitable for enhanced molecular cytogenetics

scientific article published on March 2004

FGFR3 preferentially colocalizes with IGH in the interphase nucleus of multiple myeloma patient B-cells when FGFR3 is located outside of CT4.

scientific article published on 11 August 2016

Filtration-based enrichment of circulating tumor cells from all prostate cancer risk groups.

scientific article published on 12 February 2017

Fluorescence in situ hybridization analysis of hobo, mdg1 and Dm412 transposable elements reveals genomic instability following the Drosophila melanogaster genome sequencing.

scientific article published on 11 July 2007

Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death

scientific article published in February 2000

Generation of functional scFv intrabody to abate the expression of CD147 surface molecule of 293A cells

scientific article

Genetic Landscape of Papillary Thyroid Carcinoma and Nuclear Architecture: An Overview Comparing Pediatric and Adult Populations

scientific article published on 27 October 2020

Genomic Analysis of Localized High-Risk Prostate Cancer Circulating Tumor Cells at the Single-Cell Level

scientific article published on 08 August 2020

Genomic Instability in Circulating Tumor Cells

scientific article published on 16 October 2020

Genomic Instability: The Driving Force behind Refractory/Relapsing Hodgkin's Lymphoma

scientific article

Global Interactomics Connect Nuclear Mitotic Apparatus Protein NUMA1 to Influenza Virus Maturation

scholarly article by Md Niaz Rahim et al published 19 December 2018 in Viruses

Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization.

scientific article

Heterozygous mutations in the PALB2 hereditary breast cancer predisposition gene impact on the three-dimensional nuclear organization of patient-derived cell lines

scientific article published on 23 January 2013

Homozygous BUB1B mutation and susceptibility to gastrointestinal neoplasia

scientific article published in December 2010

Identification of Neuroblastoma Subgroups Based on Three-Dimensional Telomere Organization.

scientific article published on August 2016

Image filtering in structured illumination microscopy using the Lukosz bound

scientific article published on October 2013

Imaging chromatin nanostructure with binding-activated localization microscopy based on DNA structure fluctuations.

scientific article

Increased genomic instability and altered chromosomal protein phosphorylation timing in HRAS-transformed mouse fibroblasts.

scientific article

Initiation of telomere-mediated chromosomal rearrangements in cancer.

scientific article published on April 2010

Introduction to the special issue "3D nuclear architecture of the genome"

scientific article published on 02 April 2019

Inversion and deletion of 16q22 defined by array CGH, FISH, and RT-PCR in a patient with AML.

scientific article

LMP1 and Dynamic Progressive Telomere Dysfunction: A Major Culprit in EBV-Associated Hodgkin's Lymphoma

scientific article published on 27 June 2017

LMP1 mediates multinuclearity through downregulation of shelterin proteins and formation of telomeric aggregates.

scientific article published on 7 January 2015

Lamin A/C: Function in Normal and Tumor Cells

scientific article published on 09 December 2020

Long-Term Dynamics of Three Dimensional Telomere Profiles in Circulating Tumor Cells in High-Risk Prostate Cancer Patients Undergoing Androgen-Deprivation and Radiation Therapy

scientific article published on 14 August 2019

Loss of HLTF function promotes intestinal carcinogenesis ⬇️

scientific article published on March 27, 2012

Loss of lamin A function increases chromatin dynamics in the nuclear interior.

scientific article published on 24 August 2015

MYCN overexpression is associated with unbalanced copy number gain, altered nuclear location, and overexpression of chromosome arm 17q genes in neuroblastoma tumors and cell lines

scientific article published on 14 July 2015

Measuring murine chromosome orientation in interphase nuclei

scientific article

Metaphase FISHing of transgenic mice recommended: FISH and SKY define BAC-mediated balanced translocation

article

Mining gene expression signature for the detection of pre-malignant melanocytes and early melanomas with risk for metastasis

scientific article

Non-random genomic instability in cancer: A fact, not an illusion

scientific article published on 12 November 2006

Novel automated three-dimensional genome scanning based on the nuclear architecture of telomeres.

scientific article published on 30 December 2010

Novel roles for A-type lamins in telomere biology and the DNA damage response pathway.

scientific article

Nuclear imaging in three dimensions: A unique tool in cancer research ⬇️

scientific article published on 06 August 2010

Nuclear remodeling as a mechanism for genomic instability in cancer.

scientific article published on January 2011

Nuclear remodeling of telomeres in chronic myeloid leukemia

scientific article published on 23 January 2013

Nucleosomal response, immediate-early gene expression and cell transformation.

scientific article

Overexpression of c-myc precedes amplification of the gene encoding dihydrofolate reductase

article

Premalignant cervical lesions are characterized by dihydrofolate reductase gene amplification and c-Myc overexpression: possible biomarkers

scientific article published in October 2007

Profiling Three-Dimensional Nuclear Telomeric Architecture of Myelodysplastic Syndromes and Acute Myeloid Leukemia Defines Patient Subgroups

scientific article published on 26 April 2012

Quantitative 3D Telomeric Imaging of Buccal Cells Reveals Alzheimer's Disease-Specific Signatures

scientific article

Quantitative superresolution microscopy reveals differences in nuclear DNA organization of multiple myeloma and monoclonal gammopathy of undetermined significance.

scientific article published on May 2015

Radiation-induced activation of transcription factors in mammalian cells.

scientific article published on January 1990

Rapid separation of mononuclear hodgkin from multinuclear reed-sternberg cells.

scientific article published on March 2014

Recurrent trisomy and Robertsonian translocation of chromosome 14 in murine iPS cell lines

scientific article

Selected Telomere Length Changes and Aberrant Three-dimensional Nuclear Telomere Organization during Fast-Onset Mouse Plasmacytomas ⬇️

scientific article published on April 1, 2012

Shattered and stitched chromosomes-chromothripsis and chromoanasynthesis-manifestations of a new chromosome crisis?

scientific article

Super-Resolution Binding Activated Localization Microscopy through reversible change of DNA conformation

scientific article

Super-resolution structure of DNA significantly differs in buccal cells of controls and Alzheimer's patients

scientific article

Telomere-centromere-driven genomic instability contributes to karyotype evolution in a mouse model of melanoma

scientific article

Telomeric aggregates and end-to-end chromosomal fusions require myc box II.

scientific article published on 4 September 2006

The Use of 3D Telomere FISH for the Characterization of the Nuclear Architecture in EBV-Positive Hodgkin's Lymphoma

scientific article published in January 2017

The c-myc protein represses the lambda 5 and TdT initiators.

scientific article published on January 1995

The ribonucleotide reductase R2 gene is a non-transcribed target of c-Myc-induced genomic instability

article

The three-dimensional cancer nucleus

scientific article published on 21 January 2019

The three-dimensional organization of telomeres in the nucleus of mammalian cells

scientific article

Three-Dimensional Nuclear Telomere Profiling as a Biomarker for Recurrence in Oligodendrogliomas: A Pilot Study

scientific article published on 12 November 2020

Three-Dimensional Telomeric Analysis of Isolated Circulating Tumor Cells (CTCs) Defines CTC Subpopulations ⬇️

scientific article published on February 1, 2013

Three-dimensional Telomere Signatures of Hodgkin- and Reed-Sternberg Cells at Diagnosis Identify Patients with Poor Response to Conventional Chemotherapy

scientific article

Three-dimensional nuclear telomere architecture changes during endometrial carcinoma development

scientific article published on 30 April 2013

Three-dimensional nuclear telomere architecture is associated with differential time to progression and overall survival in glioblastoma patients

scientific article

Three-dimensional quantitative imaging of telomeres in buccal cells identifies mild, moderate, and severe Alzheimer's disease patients

scientific article published in January 2014

Three-dimensional structured illumination microscopy using Lukosz bound apodization reduces pixel negativity at no resolution cost

scientific article published in May 2014

Three-dimensional telomere architecture of esophageal squamous cell carcinoma: comparison of tumor and normal epithelial cells.

scientific article published on 27 January 2015

Three-dimensional telomere dynamics in follicular thyroid cancer

scientific article published on 04 September 2013

Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response

scientific article published in Nature

Translocation frequencies and chromosomal proximities for selected mouse chromosomes in primary B lymphocytes ⬇️

scientific article published on 08 March 2011

Uncoupling of genomic instability and tumorigenesis in a mouse model of Burkitt's lymphoma expressing a conditional box II-deleted Myc protein

scientific article published on 01 April 2005

XPO1 Inhibition Preferentially Disrupts the 3D Nuclear Organization of Telomeres in Tumor Cells.

scientific article published on 17 March 2016

c-MYC-induced genomic instability.

scientific article published on April 2014

c-Myc induces chromosomal rearrangements through telomere and chromosome remodeling in the interphase nucleus

scientific article

c-Myc-induced genomic instability.

scientific article published on January 2003

p53 CRISPR Deletion Affects DNA Structure and Nuclear Architecture

scientific article published on 22 February 2020

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