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List of works by Puthen Jithesh

A collection of annotated and harmonized human breast cancer transcriptome datasets, including immunologic classification.

scientific article published on 20 March 2017

A systems biology approach identifies SART1 as a novel determinant of both 5-fluorouracil and SN38 drug resistance in colorectal cancer.

scientific article

ADAM17-dependent c-MET-STAT3 signaling mediates resistance to MEK inhibitors in KRAS mutant colorectal cancer.

scientific article published on 12 June 2014

AKT1 has dual actions on the glucocorticoid receptor by cooperating with 14-3-3.

scientific article published on 4 October 2016

Abstract 1431: Gene expression analysis of argininosuccinate synthetase loss and the effects of pegylated arginine deiminase in malignant pleural mesothelioma

article

Accelerating next generation sequencing data analysis with system level optimizations.

scientific article

Analysis of Gene Expression in 3D Spheroids Highlights a Survival Role for ASS1 in Mesothelioma

scientific article

Depletion of Human DNA in Spiked Clinical Specimens for Improvement of Sensitivity of Pathogen Detection by Next-Generation Sequencing

scientific article published on 13 January 2016

Diagnosis implications of the whole genome sequencing in a large Lebanese family with hyaline fibromatosis syndrome.

scientific article

Distinct miRNA profiles in normal and gastric cancer myofibroblasts and significance in Wnt signaling

scientific article

Erratum to: Diagnosis implications of the whole genome sequencing in a large Lebanese family with hyaline fibromatosis syndrome

scientific article published on February 2017

Estrogen receptor β activation impairs mitochondrial oxidative metabolism and affects malignant mesothelioma cell growth in vitro and in vivo.

scientific article published on 23 September 2013

Exome sequencing of synchronously resected primary colorectal tumours and colorectal liver metastases to inform oncosurgical management

scientific article published on 13 November 2017

FKBPL regulates estrogen receptor signaling and determines response to endocrine therapy

scientific article

FKBPL: a novel prognostic and predictive biomarker?

scientific article published on 18 May 2010

From genomes to genomic medicine: enabling personalized and precision medicine in the Middle East

scientific article published on 01 September 2017

Gene expression meta-analysis identifies VDAC1 as a predictor of poor outcome in early stage non-small cell lung cancer

scientific article

Gene expression profiling in bladder cancer identifies potential therapeutic targets

scientific article published on 02 March 2017

Genome sequencing data analysis for rare disease gene discovery

scientific article published on 17 August 2021

Genome-wide Regulatory Roles of the C2H2-type Zinc Finger Protein ZNF764 on the Glucocorticoid Receptor.

scientific article published on 31 January 2017

Identification of RBCK1 as a novel regulator of FKBPL: implications for tumor growth and response to tamoxifen.

scientific article published on 5 August 2013

Identification of galanin and its receptor GalR1 as novel determinants of resistance to chemotherapy and potential biomarkers in colorectal cancer

scientific article

KDM6B histone demethylase is an epigenetic regulator of estrogen receptor β expression in human pleural mesothelioma.

scientific article

Monoallelic expression in melanoma

scientific article published on 05 April 2019

Proteomic profiling of rectal cancer reveals acid ceramidase is implicated in radiation response.

scientific article published on 5 March 2018

Ran GTPase promotes cancer progression via Met recepto-rmediated downstream signaling.

scientific article published on 03 October 2016

SIRT1 at the crossroads of AKT1 and ERβ in malignant pleural mesothelioma cells

scientific article

Seven novel glucose-6-phosphate dehydrogenase (G6PD) deficiency variants identified in the Qatari population

scientific article published on 07 October 2021

Targeting treatment-resistant breast cancer stem cells with FKBPL and its peptide derivative, AD-01, via the CD44 pathway

scientific article published on 5 June 2013

Temple-Baraitser Syndrome and Zimmermann-Laband Syndrome: one clinical entity?

scientific article

The colorectal cancer disease-specific transcriptome may facilitate the discovery of more biologically and clinically relevant information

scientific article

The epigenetic landscape of oral squamous cell carcinoma ⬇️

scientific article published on January 3, 2013

The unfolded protein response: a novel therapeutic target for poor prognostic BRAF mutant colorectal cancer

scientific article published on 26 February 2018

Total proteome analysis identifies migration defects as a major pathogenetic factor in immunoglobulin heavy chain variable region (IGHV)-unmutated chronic lymphocytic leukemia.

scientific article

Transcriptional subtyping and CD8 immunohistochemistry identifies poor prognosis stage II/III colorectal cancer patients who benefit from adjuvant chemotherapy

scientific article published on 01 June 2018

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