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List of works by Marcelo Farina

17β-estradiol decreases methylmercury-induced neurotoxicity in male mice.

scientific article published on 21 November 2008

A study of the relative importance of the peroxiredoxin-, catalase-, and glutathione-dependent systems in neural peroxide metabolism ⬇️

scientific article published on March 24, 2011

Acetaldehyde does not inhibit glutathione peroxidase and glutathione reductase from mouse liver in vitro

scientific article published on 4 January 2006

Acute exposure of rabbits to diphenyl diselenide: a toxicological evaluation

scientific article published on 13 July 2010

Additive pro-oxidative effects of methylmercury and ebselen in liver from suckling rat pups

scientific article published in February 2004

Age-related cognitive decline in hypercholesterolemic LDL receptor knockout mice (LDLr-/-): evidence of antioxidant imbalance and increased acetylcholinesterase activity in the prefrontal cortex

scientific article published in January 2012

Agmatine abolishes restraint stress-induced depressive-like behavior and hippocampal antioxidant imbalance in mice.

scientific article published on 24 December 2013

Agmatine attenuates reserpine-induced oral dyskinesia in mice: Role of oxidative stress, nitric oxide and glutamate NMDA receptors

scientific article published on 12 June 2016

Anticonvulsant effect of GMP depends on its conversion to guanosine.

scientific article published in April 2004

Antidepressant Effects of Probucol on Early-Symptomatic YAC128 Transgenic Mice for Huntington's Disease

scientific article published on 14 August 2018

Antinociceptive effect of the Polygala sabulosa hydroalcoholic extract in mice: evidence for the involvement of glutamatergic receptors and cytokine pathways.

scientific article published in July 2008

Antinociceptive properties of the hydroalcoholic extract and the flavonoid rutin obtained from Polygala paniculata L. in mice.

scientific article published on 5 March 2009

Antioxidant and acetylcholinesterase response to repeated malathion exposure in rat cerebral cortex and hippocampus.

scientific article

Antioxidant effect of diphenyl diselenide against sodium nitroprusside (SNP) induced lipid peroxidation in human platelets and erythrocyte membranes: an in vitro evaluation

scientific article published on 12 September 2006

Antioxidant responses and lipid peroxidation following intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in rats: increased susceptibility of olfactory bulb

scientific article published on 24 February 2007

Antioxidants and metallothionein levels in mercury-treated mice

scientific article published on 11 September 2006

Anxiolytic-like, stimulant and neuroprotective effects of Ilex paraguariensis extracts in mice

scientific article

Ascorbic acid treatment, similarly to fluoxetine, reverses depressive-like behavior and brain oxidative damage induced by chronic unpredictable stress

scientific article

Atorvastatin Prevents Cognitive Deficits Induced by Intracerebroventricular Amyloid-β1-40 Administration in Mice: Involvement of Glutamatergic and Antioxidant Systems.

scientific article published in April 2015

Behavioral effects of developmental methylmercury drinking water exposure in rodents

scientific article published on 07 October 2013

Behavioral impairments related to lead-induced developmental neurotoxicity in chicks

scientific article published on 21 December 2007

Behavioral, morphological, and biochemical changes after in ovo exposure to methylmercury in chicks

scientific article published on 6 August 2008

Biomarkers of mercury toxicity: Past, present, and future trends.

scientific article published on 05 April 2017

Both creatine and its product phosphocreatine reduce oxidative stress and afford neuroprotection in an in vitro Parkinson's model

scientific article published on 24 November 2014

Cerebellar thiol status and motor deficit after lactational exposure to methylmercury.

scientific article published on 29 March 2006

Cipura paludosa extract prevents methyl mercury-induced neurotoxicity in mice.

scientific article

Clarified Açaí (Euterpe oleracea) Juice as an Anticonvulsant Agent: In Vitro Mechanistic Study of GABAergic Targets.

scientific article

Comparative study of quercetin and its two glycoside derivatives quercitrin and rutin against methylmercury (MeHg)-induced ROS production in rat brain slices.

scientific article published on 10 November 2009

Comparative study on methyl- and ethylmercury-induced toxicity in C6 glioma cells and the potential role of LAT-1 in mediating mercurial-thiol complexes uptake

scientific article published on 30 May 2013

Comparative study on the response of rat primary astrocytes and microglia to methylmercury toxicity

scientific article

Complex methylmercury-cysteine alters mercury accumulation in different tissues of mice.

scientific article published in October 2010

Confinement during field studies may jeopardize antioxidant and physiological responses of Nile tilapia to contaminants

article

Decreased forelimb ability in mice intracerebroventricularly injected with low dose 6-hydroxidopamine: A model on the dissociation of bradykinesia from hypokinesia.

scientific article

Delta-aminolevulinate dehydratase inhibition by phenyl selenoacetylene: effect of reaction with hydrogen peroxide.

scientific article

Design, Synthesis, and In Vitro Evaluation of a Novel Probucol Derivative: Protective Activity in Neuronal Cells Through GPx Upregulation.

scientific article published on 12 February 2018

Developmental exposure to manganese induces lasting motor and cognitive impairment in rats

scientific article

Differential susceptibility following beta-amyloid peptide-(1-40) administration in C57BL/6 and Swiss albino mice: Evidence for a dissociation between cognitive deficits and the glutathione system response

scientific article published on 27 December 2006

Diphenyl diselenide administration enhances cortical mitochondrial number and activity by increasing hemeoxygenase type 1 content in a methylmercury-induced neurotoxicity mouse model.

scientific article published on 13 March 2014

Diphenyl diselenide confers neuroprotection against hydrogen peroxide toxicity in hippocampal slices

scientific article

Diphenyl diselenide decreases serum levels of total cholesterol and tissue oxidative stress in cholesterol-fed rabbits

scientific article

Diphenyl diselenide modulates oxLDL-induced cytotoxicity in macrophage by improving the redox signaling.

scientific article published on 23 April 2013

Diphenyl diselenide prevents cortico-cerebral mitochondrial dysfunction and oxidative stress induced by hypercholesterolemia in LDL receptor knockout mice

scientific article published on 24 July 2013

Diphenyl diselenide protects neuronal cells against oxidative stress and mitochondrial dysfunction: Involvement of the glutathione-dependent antioxidant system

scientific article published on 25 September 2018

Diphenyl diselenide, a simple glutathione peroxidase mimetic, inhibits human LDL oxidation in vitro.

scientific article published on 13 March 2008

Diphenyl diselenide, a simple organoselenium compound, decreases methylmercury-induced cerebral, hepatic and renal oxidative stress and mercury deposition in adult mice

scientific article published on 29 November 2008

Diphenyl ditelluride targets brain selenoproteins in vivo: inhibition of cerebral thioredoxin reductase and glutathione peroxidase in mice after acute exposure

scientific article published on 12 August 2012

Does methylmercury exposure to the offspring end at birth?

scientific article published on 30 October 2008

Does methylmercury-induced hypercholesterolemia play a causal role in its neurotoxicity and cardiovascular disease?

scientific article published on 17 August 2012

Ebselen protects against methylmercury-induced inhibition of glutamate uptake by cortical slices from adult mice.

scientific article published in October 2003

Effects of 2,3-dimercapto-1-propanesulfonic acid (DMPS) on methylmercury-induced locomotor deficits and cerebellar toxicity in mice

article

Effects of K074 and pralidoxime on antioxidant and acetylcholinesterase response in malathion-poisoned mice

scientific article published on 22 June 2011

Effects of aluminum sulfate on erythropoiesis in rats

scientific article published in June 2002

Effects of ethanol and diphenyl diselenide exposure on the activity of delta-aminolevulinate dehydratase from mouse liver and brain.

scientific article published on 20 December 2005

Effects of glyoxal or methylglyoxal on the metabolism of amino acids, lactate, glucose and acetate in the cerebral cortex of young and adult rats.

scientific article published on 18 December 2009

Effects of inorganic selenium administration in methylmercury-induced neurotoxicity in mouse cerebral cortex.

scientific article published on 8 July 2010

Effects of lifestyle modifications on cognitive impairments in a mouse model of hypercholesterolemia

scientific article published on 5 March 2013

Effects of traumatic brain injury of different severities on emotional, cognitive, and oxidative stress-related parameters in mice

scientific article published on October 2010

Epigallocatechin-3-gallate protects rat brain mitochondria against cadmium-induced damage

scientific article published on 21 July 2011

Ethanol inhibits δ-aminolevulinate dehydratase and glutathione peroxidase activities in mice liver: Protective effects of ebselen and N-acetylcysteine

scientific article published on 27 December 2005

Ethnic Kawasaki Disease Risk Associated with Blood Mercury and Cadmium in U.S. Children

scientific article published on 5 January 2016

Experimental hypothyroidism inhibits delta-aminolevulinate dehydratase activity in neonatal rat blood and liver

scientific journal article

Expression of tyrosine hydroxylase increases the resistance of human neuroblastoma cells to oxidative insults.

scientific article published on 8 October 2009

Folic acid prevents depressive-like behavior and hippocampal antioxidant imbalance induced by restraint stress in mice

scientific article published on 8 November 2012

GABA-A receptor modulators alter emotionality and hippocampal theta rhythm in an animal model of long-lasting anxiety

scientific article published in August 2013

Gender effects of acute malathion or zinc exposure on the antioxidant response of rat hippocampus and cerebral cortex.

scientific article published on December 2010

Glia and methylmercury neurotoxicity

scientific article

Glutathione in Chlorpyrifos-and Chlorpyrifos-Oxon-Induced Toxicity: a Comparative Study Focused on Non-cholinergic Toxicity in HT22 Cells

scientific article published on 10 July 2020

Guanosine and synthetic organoselenium compounds modulate methylmercury-induced oxidative stress in rat brain cortical slices: involvement of oxidative stress and glutamatergic system

scientific article published on 30 December 2008

Guanosine prevents behavioral alterations in the forced swimming test and hippocampal oxidative damage induced by acute restraint stress

scientific article published on 12 October 2014

Hematological changes in rats chronically exposed to oral aluminum

scientific article

Hemolytic effects of sodium selenite and mercuric chloride in human blood

scientific article

High fat and highly thermolyzed fat diets promote insulin resistance and increase DNA damage in rats.

scientific article published in November 2009

Hypercholesterolemia induces short-term spatial memory impairments in mice: up-regulation of acetylcholinesterase activity as an early and causal event?

scientific article published on 29 October 2013

Improved neuroprotective effects of resveratrol-loaded polysorbate 80-coated poly(lactide) nanoparticles in MPTP-induced Parkinsonism.

scientific article published in January 2015

In vitro effects of selenite and mercuric chloride on liver thiobarbituric acid-reactive substances and non-protein thiols from rats: influences of dietary cholesterol and polyunsaturated and saturated fatty acids.

scientific article

In vitro manganese exposure disrupts MAPK signaling pathways in striatal and hippocampal slices from immature rats

scientific article

In vitro reactivating effects of standard and newly developed oximes on malaoxon-inhibited mouse brain acetylcholinesterase

scientific article published on 12 April 2010

Increased susceptibility to amyloid-β-induced neurotoxicity in mice lacking the low-density lipoprotein receptor

scientific article published in January 2014

Inhibition of reductase systems by 2-AAPA modulates peroxiredoxin oxidation and mitochondrial function in A172 glioblastoma cells.

scientific article published on 28 April 2017

Interaction between metals and chelating agents affects glutamate binding on brain synaptic membranes.

scientific article

Interaction of curcumin with manganese may compromise metal and neurotransmitter homeostasis in the hippocampus of young mice.

scientific article published on 11 April 2014

Involvement of glutamate and reactive oxygen species in methylmercury neurotoxicity.

scientific article published on March 2007

Involvement of glutathione, ERK1/2 phosphorylation and BDNF expression in the antidepressant-like effect of zinc in rats.

scientific article

Involvement of superoxide in malaoxon-induced toxicity in primary cultures of cortical neurons

scientific article published on 29 August 2017

Is there an association between hypercholesterolemia and depression? Behavioral evidence from the LDLr(-/-) mouse experimental model.

scientific article

Lactational exposure to inorganic mercury: evidence of neurotoxic effects

scientific article

Lactational exposure to malathion inhibits brain acetylcholinesterase in mice.

scientific article published on 28 April 2006

Long-term and low-dose malathion exposure causes cognitive impairment in adult mice: evidence of hippocampal mitochondrial dysfunction, astrogliosis and apoptotic events

scientific article published on 25 January 2015

Low toxicity of diphenyl diselenide in rabbits: a long-term study.

scientific article published in July 2007

MPP+-Lesioned Mice: an Experimental Model of Motor, Emotional, Memory/Learning, and Striatal Neurochemical Dysfunctions.

scientific article published on 8 October 2016

Maternal milk as methylmercury source for suckling mice: neurotoxic effects involved with the cerebellar glutamatergic system.

scientific article

Mechanism of delta-aminolevulinate dehydratase inhibition by phenyl selenoacetylene involves its conversion to diphenyl diselenide

scientific article published in January 2005

Mechanisms of manganese-induced neurotoxicity in primary neuronal cultures: the role of manganese speciation and cell type.

scientific article published on 22 September 2011

Mechanisms of methylmercury-induced neurotoxicity: evidence from experimental studies.

scientific article

Mechanisms of the inhibitory effects of selenium and mercury on the activity of delta-aminolevulinate dehydratase from mouse liver, kidney and brain.

scientific article published in March 2003

Mercurial-induced hydrogen peroxide generation in mouse brain mitochondria: protective effects of quercetin.

scientific article published on 19 October 2007

Mercury toxicity

scientific article published on 3 September 2012

Methionine stimulates motor impairment and cerebellar mercury deposition in methylmercury-exposed mice.

scientific article published on January 2014

Methyl phenyl selenide causes heme biosynthesis impairment and its toxicity is not modified by dimethyl sulphoxide in vivo.

scientific article published in November 2004

Methylmercury and brain development: A review of recent literature

scientific article published on 04 March 2016

Methylmercury exposure for 14 days (short-term) produces behavioral and biochemical changes in mouse cerebellum, liver, and serum

scientific article published on 29 August 2017

Methylmercury increases S100B content in rat cerebrospinal fluid ⬇️

scientific article published on February 1, 2005

Methylmercury increases glutamate release from brain synaptosomes and glutamate uptake by cortical slices from suckling rat pups: modulatory effect of ebselen

scientific article published on 15 April 2003

Methylmercury neurotoxicity is associated with inhibition of the antioxidant enzyme glutathione peroxidase.

scientific article

Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen.

scientific article published on 15 February 2011

Methylmercury-induced developmental toxicity is associated with oxidative stress and cofilin phosphorylation. Cellular and human studies

scientific article

Modulation of Brain Glutathione Reductase and Peroxiredoxin 2 by α-Tocopheryl Phosphate.

scientific article published on 9 January 2016

Modulation of methylmercury uptake by methionine: prevention of mitochondrial dysfunction in rat liver slices by a mimicry mechanism

scientific article published on 27 January 2011

Motor impairment induced by oral exposure to methylmercury in adult mice

scientific article published on 01 January 2005

N-Acetylcysteine does not protect behavioral and biochemical toxicological effect after acute exposure of diphenyl ditelluride.

scientific article

Neuropeptide Y (NPY) prevents depressive-like behavior, spatial memory deficits and oxidative stress following amyloid-β (Aβ(1-40)) administration in mice

scientific article

New Probucol Analogues Inhibit Ferroptosis, Improve Mitochondrial Parameters, and Induce Glutathione Peroxidase in HT22 Cells

scientific article published on 08 June 2020

One-step liquid-liquid extraction of cocaine from urine samples for gas chromatographic analysis

scientific article published in July 2002

Organic and inorganic forms of selenium inhibited differently fish (Rhamdia quelen) and rat (Rattus norvergicus albinus) delta-aminolevulinate dehydratase

scientific journal article

Oxidative stress in MeHg-induced neurotoxicity

scientific article

Oxidative stress-mediated inhibition of brain creatine kinase activity by methylmercury.

scientific article published on 4 June 2010

Platelet oxygen consumption as a peripheral blood marker of brain energetics in a mouse model of severe neurotoxicity

scientific article published on 8 March 2013

Positive correlation between elevated plasma cholesterol levels and cognitive impairments in LDL receptor knockout mice: relevance of cortico-cerebral mitochondrial dysfunction and oxidative stress.

scientific article published on 16 September 2011

Postnatal methylmercury exposure induces hyperlocomotor activity and cerebellar oxidative stress in mice: dependence on the neurodevelopmental period.

scientific article published in April 2006

Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain.

scientific article

Probucol Protects Neuronal Cells Against Peroxide-Induced Damage and Directly Activates Glutathione Peroxidase-1

scientific article published on 06 June 2020

Probucol affords neuroprotection in a 6-OHDA mouse model of Parkinson's disease

scientific article published on 19 January 2013

Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells.

scientific article published on 21 September 2009

Probucol increases striatal glutathione peroxidase activity and protects against 3-nitropropionic acid-induced pro-oxidative damage in rats

scientific article (publication date: 2013)

Probucol mitigates streptozotocin-induced cognitive and biochemical changes in mice.

scientific article published on 22 October 2014

Probucol modulates oxidative stress and excitotoxicity in Huntington's disease models in vitro.

scientific article published on 11 January 2012

Probucol, a lipid-lowering drug, prevents cognitive and hippocampal synaptic impairments induced by amyloid β peptide in mice

scientific article

Profile of nonprotein thiols, lipid peroxidation and delta-aminolevulinate dehydratase activity in mouse kidney and liver in response to acute exposure to mercuric chloride and sodium selenite.

scientific article

Propylthiouracil-induced hypothyroidism during lactation alters leucine and mannose metabolism in rat cerebellar slices

scientific article published in January 2013

Protective effect of a novel peptide against methylmercury-induced toxicity in rat primary astrocytes.

scientific article published on 14 December 2011

Protective effects of Polygala paniculata extract against methylmercury-induced neurotoxicity in mice

scientific article published in November 2005

Protective effects of ascorbic acid on behavior and oxidative status of restraint-stressed mice

scientific article published on 3 October 2012

Protective effects of diphenyl diselenide in a mouse model of brain toxicity.

scientific article published on 14 August 2013

Protective effects of organoselenium compounds against methylmercury-induced oxidative stress in mouse brain mitochondrial-enriched fractions

scientific article published on 13 October 2011

Riboflavin acetate induces apoptosis in squamous carcinoma cells after photodynamic therapy.

scientific article published on 2 November 2015

Selenoxides inhibit delta-aminolevulinic acid dehydratase.

scientific article

Sex- and structure-specific differences in antioxidant responses to methylmercury during early development

scientific article published on 22 July 2016

Sodium selenite protects from 3-nitropropionic acid-induced oxidative stress in cultured primary cortical neurons

scientific article published on 03 December 2018

Structure-activity relationship of flavonoids derived from medicinal plants in preventing methylmercury-induced mitochondrial dysfunction.

scientific article

Sub-acute administration of (S)-dimethyl 2-(3-(phenyltellanyl) propanamido) succinate induces toxicity and oxidative stress in mice: unexpected effects of N-acetylcysteine

scientific article published on 24 April 2013

Succinobucol versus probucol: higher efficiency of succinobucol in mitigating 3-NP-induced brain mitochondrial dysfunction and oxidative stress in vitro

scientific article published on 17 January 2013

Succinobucol, a Lipid-Lowering Drug, Protects Against 3-Nitropropionic Acid-Induced Mitochondrial Dysfunction and Oxidative Stress in SH-SY5Y Cells via Upregulation of Glutathione Levels and Glutamate Cysteine Ligase Activity

scientific article

Succinobucol, a Non-Statin Hypocholesterolemic Drug, Prevents Premotor Symptoms and Nigrostriatal Neurodegeneration in an Experimental Model of Parkinson's Disease

scientific article published on 6 February 2016

Superoxide anion generation and oxidative stress in methylmercury-induced endothelial toxicity in vitro

scientific article

Temporal effects of newly developed oximes (K027, K048) on malathion-induced acetylcholinesterase inhibition and lipid peroxidation in mouse prefrontal cortex

scientific article published on 18 October 2007

The methylmercury-L-cysteine conjugate is a substrate for the L-type large neutral amino acid transporter

scientific article published on 13 September 2008

Time course evaluation of behavioral impairments in the pilocarpine model of epilepsy

scientific article published on 12 January 2016

Toxicity of ethylmercury (and Thimerosal): a comparison with methylmercury.

scientific article

Toxicology of metals and metalloids

scientific article published on 22 May 2014

Tyrosine hydroxylase regulation in adult rat striatum following short-term neonatal exposure to manganese

scientific article published on 21 January 2016

Zinc reverses malathion-induced impairment in antioxidant defenses.

scientific article published on 4 March 2009

γ-Glutamylcysteine ameliorates oxidative injury in neurons and astrocytes in vitro and increases brain glutathione in vivo.

scientific article

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