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List of works by Joaquim Roca Bosch

A GyrB-GyrA fusion protein expressed in yeast cells is able to remove DNA supercoils but cannot substitute eukaryotic topoisomerase II.

scientific article

Asymmetric removal of supercoils suggests how topoisomerase II simplifies DNA topology

scientific article published on 01 January 2004

Chromatin regulates DNA torsional energy via topoisomerase II-mediated relaxation of positive supercoils

scientific article

Cloning, functional analysis and post-transcriptional regulation of a type II DNA topoisomerase from Leishmania infantum. A new potential target for anti-parasite drugs.

scientific article

Condensin minimizes topoisomerase II-mediated entanglements of DNA in vivo

scientific article published on 06 November 2020

DNA Topology and Global Architecture of Point Centromeres

scientific article published on 17 October 2015

DNA knots occur in intracellular chromatin.

scientific article published on 15 November 2017

DNA knots reveal a chiral organization of DNA in phage capsids

scientific article published on 15 June 2005

DNA transport by a type II DNA topoisomerase: evidence in favor of a two-gate mechanism

scientific article published on 01 May 1994

Dysbiosis and relapse-related microbiome in inflammatory bowel disease: A shotgun metagenomic approach

scientific article published on 02 December 2021

Electrophoretic Analysis of the DNA Supercoiling Activity of DNA Gyrase

scientific article published on 01 January 2018

Expression of transgenic PPP1CC2 in the testis of Ppp1cc-null mice rescues spermatid viability and spermiation but does not restore normal sperm tail ultrastructure, sperm motility, or fertility

scientific article

Failure to relax negative supercoiling of DNA is a primary cause of mitotic hyper-recombination in topoisomerase-deficient yeast cells.

scientific article

Fractal dimension and localization of DNA knots

scientific article published on 29 January 2007

Genome urbanization: clusters of topologically co-regulated genes delineate functional compartments in the genome of Saccharomyces cerevisiae

scientific article

Human gut metatranscriptome changes induced by a fermented milk product are associated with improved tolerance to a flatulogenic diet

scientific article published on 05 April 2022

In silico, in vitro and in vivo imageries of type II topoisomerases: Comment on "Disentangling DNA molecules" by Alexander Vologodskii

scientific article published on 08 July 2016

Intracellular nucleosomes constrain a DNA linking number difference of -1.26 that reconciles the Lk paradox

scientific article published in Nature Communications

Positional dependence of transcriptional inhibition by DNA torsional stress in yeast chromosomes

scientific article published on 7 January 2010

Production of highly knotted DNA by means of cosmid circularization inside phage capsids

scientific article

Quantitative disclosure of DNA knot chirality by high-resolution 2D-gel electrophoresis

scientific article published on 01 March 2019

Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach

scientific article (publication date: February 2006)

Structure and Chromosomal Organization of Yeast Genes Regulated by Topoisomerase II.

scientific article published on 3 January 2018

The capture of a DNA double helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerases

scientific article published on 01 November 1992

The mechanisms of DNA topoisomerases

scientific article

The path of the DNA along the dimer interface of topoisomerase II.

scientific article published on 27 March 2004

The torsional state of DNA within the chromosome

scientific article published on May 13, 2011

Topoisomerase II is required for the production of long Pol II gene transcripts in yeast

scientific article published on 19 June 2012

Topoisomerase II minimizes DNA entanglements by proofreading DNA topology after DNA strand passage

scientific article published on 31 October 2013

Topoisomerase II regulates yeast genes with singular chromatin architectures

scientific article published on 09 August 2013

Topoisomerase II, not topoisomerase I, is the proficient relaxase of nucleosomal DNA.

scientific article published on 18 May 2006

Topoisomerase II: a fitted mechanism for the chromatin landscape.

scientific article published on 05 December 2008

Transcriptional inhibition by DNA torsional stress.

scientific article published on March 2011

Transcriptional supercoiling boosts topoisomerase II-mediated knotting of intracellular DNA

scientific article published on 01 July 2019