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List of works by Guntram Suske

A comparison of mouse and rabbit embryos for the production of transgenic animals by pronuclear microinjection.

scientific article published in November 1990

A transgenic mouse model for lung adenocarcinoma.

scientific article published on January 1995

An inhibitor domain in Sp3 regulates its glutamine-rich activation domains.

scientific article published on October 1996

Binding of the ubiquitous cellular transcription factors Sp1 and Sp3 to the ZI domains in the Epstein-Barr virus lytic switch BZLF1 gene promoter

scientific article published on February 1997

Cell-specific, developmentally and hormonally regulated expression of the rabbit uteroglobin transgene and the endogenous mouse uteroglobin gene in transgenic mice

scientific article published in March 1991

Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes

scientific article

Combinatorial Action of HNF3 and Sp Family Transcription Factors in the Activation of the Rabbit Uteroglobin/CC10 Promoter

scientific article published on April 17, 1998

Complex phenotype of mice homozygous for a null mutation in the Sp4 transcription factor gene.

scientific article

Complexity of translationally controlled transcription factor Sp3 isoform expression.

scientific article published on 9 July 2004

Differential regulation of sense and antisense promoter activity at the Csf1R locus in B cells by the transcription factor PAX5.

scientific article published on 23 April 2011

Differential transcriptional regulation of c-myc promoter through the same DNA binding sites targeted by Sp1-like proteins

scientific article published in May 1995

E2F and Sp1/Sp3 Synergize but are not sufficient to activate the MYCN gene in neuroblastomas.

scientific article published on 26 November 2003

Elements of the rabbit uteroglobin promoter mediating its transcription in epithelial cells from the endometrium and lung.

scientific article published on January 1992

Epigenetic silencing of spermatocyte-specific and neuronal genes by SUMO modification of the transcription factor Sp3.

scientific article

Expression of the uteroglobin promoter in epithelial cell lines from endometrium.

scientific article published on January 1991

Genome-wide localization and expression profiling establish Sp2 as a sequence-specific transcription factor regulating vitally important genes

scientific article published on 7 June 2012

High Sp1/Sp3 ratios in epithelial cells during epithelial differentiation and cellular transformation correlate with the activation of the HPV-16 promoter.

scientific article published on October 1996

High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A

scientific journal article

Human CC10, the homologue of rabbit uteroglobin: genomic cloning, chromosomal localization and expression in endometrial cell lines

scientific article (publication date: September 1992)

Human Sp3 transcriptional regulator gene (SP3) maps to chromosome 2q31

scientific article published on 01 November 1996

Human Sp4 transcription factor gene (SP4) maps to chromosome 7p15.

scientific article

Identification of SUMO-dependent chromatin-associated transcriptional repression components by a genome-wide RNAi screen.

scientific article published in March 2008

Identification of residues essential for progesterone binding to uteroglobin by site-directed mutagenesis

scientific article

Impaired hematopoiesis in mice lacking the transcription factor Sp3

scientific journal article

Impaired ossification in mice lacking the transcription factor Sp3.

scientific article

In vitro chemo- and radio-resistance in small cell lung cancer correlates with cell adhesion and constitutive activation of AKT and MAP kinase pathways

scientific article published in December 2002

Interchain cysteine bridges control entry of progesterone to the central cavity of the uteroglobin dimer

scientific article published on June 1992

Isolation and structure of the gene for the progesterone-inducible protein uteroglobin.

scientific article

Ligand binding reduces SUMOylation of the peroxisome proliferator-activated receptor γ (PPARγ) activation function 1 (AF1) domain

scientific article

MGA, L3MBTL2 and E2F6 determine genomic binding of the non-canonical Polycomb repressive complex PRC1.6.

scientific article

Mammalian SP/KLF transcription factors: bring in the family

scientific article (publication date: May 2005)

Mechanism of gene regulation by steroid hormones

article

NF-Y and SP transcription factors - New insights in a long-standing liaison

scientific article

Oxidative stress regulates vascular endothelial growth factor-A gene transcription through Sp1- and Sp3-dependent activation of two proximal GC-rich promoter elements

scientific article published on 30 December 2002

PPARalpha activators inhibit vascular endothelial growth factor receptor-2 expression by repressing Sp1-dependent DNA binding and transactivation

scientific article published on 18 December 2003

Progesterone binding to uteroglobin: two alternative orientations of the ligand

scientific article

Protein-DNA interactions at steroid hormone regulated genes

scientific article

RAP1-like binding activity in islet cells corresponds to members of the Sp1 family of transcription factors

scientific article published on 01 July 1997

Recombinant rabbit uteroglobin expressed at high levels in E. coli forms stable dimers and binds progesterone.

scientific article published on October 1989

Regulation of heme oxygenase-1 gene expression through the phosphatidylinositol 3-kinase/PKC-zeta pathway and Sp1.

scientific article published on 21 April 2006

Role of Sp1 in cAMP-dependent transcriptional regulation of the bovine CYP11A gene.

scientific article published on July 1999

SUMOylation of the polycomb group protein L3MBTL2 facilitates repression of its target genes.

scientific article published on 24 December 2013

Sp1 and Sp3 transcription factors mediate interleukin-1 beta down-regulation of human type II collagen gene expression in articular chondrocytes.

scientific article

Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3.

scientific article published in December 1995

Sp1-mediated transcriptional activation is repressed by Sp3

scientific article

Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects

scientific journal article

Sp1/Sp3 transcription factors regulate hallmarks of megakaryocyte maturation and platelet formation and function.

scientific article

Sp2 is the only glutamine-rich specificity protein with minor impact on development and differentiation in myelinating glia

scientific article published on 27 November 2016

Sp3 represses the Sp1-mediated transactivation of the human COL2A1 gene in primary and de-differentiated chondrocytes

scientific article published on 10 July 2001

Specificity protein 2 (Sp2) is essential for mouse development and autonomous proliferation of mouse embryonic fibroblasts

scientific journal article

Structure and regulated expression of the uteroglobin gene

scientific article published on 01 January 1982

Synergistic activation of the human Btk promoter by transcription factors Sp1/3 and PU.1.

scientific article published on 01 June 1999

The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene.

scientific article

The uteroglobin promoter targets expression of the SV40 T antigen to a variety of secretory epithelial cells in transgenic mice

scientific article published on 01 October 1994

Transcription factor Sp2 potentiates binding of the TALE homeoproteins Pbx1:Prep1 and the histone-fold domain protein Nf-y to composite genomic sites

scientific article published in Journal of Biological Chemistry

Transcription factor Sp3 is silenced through SUMO modification by PIAS1

scientific article

Transcription factor Sp3 knockout mice display serious cardiac malformations.

scientific article

Uteroglobin, an apically secreted protein of the uterine epithelium, is secreted non-polarized from MDCK cells and mainly basolaterally from Caco-2 cell

scientific article published on 01 September 1993

Vectors for inducible expression of dual epitope-tagged proteins in insect cells

scientific article published on 01 June 1999

Zinc finger independent genome-wide binding of Sp2 potentiates recruitment of histone-fold protein Nf-y distinguishing it from Sp1 and Sp3.

scientific article published on 20 March 2015