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List of works by Charleen T. Chu

6-Hydroxydopamine induces mitochondrial ERK activation.

scientific article

A 67 Year-Old Man with Multiple Sclerosis and New Cerebellar Lesions

scientific article published in July 2015

A comprehensive glossary of autophagy-related molecules and processes (2nd edition)

scientific article

A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease

scientific article

ATP13A2 regulates mitochondrial bioenergetics through macroautophagy

scientific journal article

Acanthamoeba keratitis: a clinicopathologic case report and review of the literature.

scientific article published on 17 January 2013

Activated alpha 2-macroglobulin promotes mitogenesis in rat vascular smooth muscle cells by a mechanism that is independent of growth-factor-carrier activity.

scientific article

Activated human plasma carboxypeptidase B is retained in the blood by binding to alpha2-macroglobulin and pregnancy zone protein

scientific article

After the banquet: mitochondrial biogenesis, mitophagy, and cell survival

scientific article

Altered expression of extracellular superoxide dismutase in mouse lung after bleomycin treatment

scientific article published on 01 November 2001

Altered transcription factor trafficking in oxidatively-stressed neuronal cells.

scientific article

Association of the mt-ND2 5178A/C polymorphism with Parkinson's disease

scientific article published on 12 December 2014

Asymptomatic giant-cell (temporal) arteritis involving the bilateral adnexa: case report and literature review.

scientific article published on July 2007

Autophagic stress in neuronal injury and disease.

scientific article published in May 2006

Autophagy in different flavors: Dysregulated protein degradation in neurological diseases ⬇️

scientific article published on April 2, 2011

Autophagy in neurite injury and neurodegeneration: in vitro and in vivo models

scientific article published on January 2009

Autophagy in neuroprotection and neurodegeneration: A question of balance.

scientific article published on May 2008

Autophagy is Increased after Traumatic Brain Injury in Mice and is Partially Inhibited by the Antioxidant γ-glutamylcysteinyl Ethyl Ester

article

Autophagy is increased in mice after traumatic brain injury and is detectable in human brain after trauma and critical illness

scientific article published on 15 October 2007

Autophagy, mitochondria and cell death in lysosomal storage diseases.

scientific article published on 23 May 2007

Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death

scientific article published on 25 June 2007

Beyond mitophagy: cytosolic PINK1 as a messenger of mitochondrial health

scientific article

Beyond the mitochondrion: cytosolic PINK1 remodels dendrites through protein kinase A

scientific article

Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization.

scientific article

Biphasic regulation of lysosomal exocytosis by oxidative stress

scientific article

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

journal article published in 2013

Career characteristics of graduates of a Medical Scientist Training Program, 1970-1990.

scientific article published in May 1996

Chronic treatment with the complex I inhibitor MPP+ depletes endogenous PTEN-induced kinase 1(PINK1) via upregulation of BCL-2-associated athanogene 6

scientific article published on 24 April 2020

Cytoplasmic aggregates of phosphorylated extracellular signal-regulated protein kinases in Lewy body diseases ⬇️

scientific article published on December 2002

Decreased SIRT2 activity leads to altered microtubule dynamics in oxidatively-stressed neuronal cells: implications for Parkinson's disease.

scientific article

Diagnosis of intracranial vasculitis: a multi-disciplinary approach

scientific article published in January 1998

Diversity in the regulation of autophagy and mitophagy: lessons from Parkinson's disease.

scientific article

E3 ligase subunit Fbxo15 and PINK1 kinase regulate cardiolipin synthase 1 stability and mitochondrial function in pneumonia

scientific article

ERK-mediated phosphorylation of TFAM downregulates mitochondrial transcription: implications for Parkinson's disease

scientific article

ERKed by LRRK2: a cell biological perspective on hereditary and sporadic Parkinson's disease

scientific article

Eaten alive: autophagy and neuronal cell death after hypoxia-ischemia.

scientific article published on 17 January 2008

Electron microscopic diagnosis of human flavivirus encephalitis: use of confocal microscopy as an aid.

scientific article

Epidermoid cyst of the thoracic spine: case history

article

Exercise increases mitochondrial complex I activity and DRP1 expression in the brains of aged mice.

scientific article published on 17 January 2017

Functional analysis of plasma alpha(2)-macroglobulin from Alzheimer's disease patients with the A2M intronic deletion.

scientific article published in December 2003

Functional repression of cAMP response element in 6-hydroxydopamine-treated neuronal cells.

scientific article published on 18 April 2006

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

scientific article

Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase.

scientific article

Human mesenchymal stem cells/multipotent stromal cells consume accumulated autophagosomes early in differentiation

scientific article published on 17 December 2014

INTRAOCULAR SYNOVIAL SARCOMA

scientific article published on 01 September 2017

Impaired mitochondrial biogenesis contributes to depletion of functional mitochondria in chronic MPP+ toxicity: dual roles for ERK1/2

scientific article

In vivo effects of single intra-articular injection of 0.5% bupivacaine on articular cartilage.

scientific article published in March 2010

Infectious crystalline keratopathy predominantly affecting the posterior cornea

scientific article published on 15 July 2014

Interactions between cytokines and alpha 2-macroglobulin

scientific article

Intracranial extramedullary hematopoiesis associated with pilocytic astrocytoma: a case report

scientific article published on 30 September 2003

Introduction. Autophagy dysregulation in neuropathology

scientific article

It's a cell-eat-cell world: autophagy and phagocytosis.

scientific article

Kinase signaling cascades in the mitochondrion: a matter of life or death.

scientific article

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

scientific article

Manganese superoxide dismutase protects against 6-hydroxydopamine injury in mouse brains.

scientific article published on 8 March 2005

Mechanism of insulin incorporation into .alpha.2-macroglobulin: implications for the study of peptide and growth factor binding

scientific article published on 01 February 1991

Mechanisms of selective autophagy and mitophagy: Implications for neurodegenerative diseases.

scientific article published on 17 July 2018

Mild mitochondrial metabolic deficits by α-ketoglutarate dehydrogenase inhibition cause prominent changes in intracellular autophagic signaling: Potential role in the pathobiology of Alzheimer's disease

scientific article

Mitochondria and Parkinson's disease

scientific article published on January 2011

Mitochondrial Calcium Dysregulation Contributes to Dendrite Degeneration Mediated by PD/LBD-Associated LRRK2 Mutants

scientific article published on 16 October 2017

Mitochondrial DNA damage: molecular marker of vulnerable nigral neurons in Parkinson's disease

scientific article

Mitochondrial Dysfunction Accompanied by ERK-Dependent Phosphorylation of TFAM in a Chronic MPP+ Model

Mitochondrial Dysfunction in Parkinson's Disease

scientific article published on 01 January 2010

Mitochondrial aberrations in mucolipidosis Type IV.

scientific article published on 20 October 2006

Mitochondrial autophagy as a compensatory response to PINK1 deficiency

scientific article

Mitochondrial kinases in Parkinson's disease: converging insights from neurotoxin and genetic models

scientific article published on 27 June 2009

Mitochondrial quality control: insights on how Parkinson's disease related genes PINK1, parkin, and Omi/HtrA2 interact to maintain mitochondrial homeostasis

scientific article

Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: implications for Parkinson's disease

scientific article published on 16 June 2008

Mitochondrially localized PKA reverses mitochondrial pathology and dysfunction in a cellular model of Parkinson's disease.

scientific article

Molecular definitions of autophagy and related processes.

scientific article published on 08 June 2017

Monitoring mitophagy in neuronal cell cultures

scientific article published on January 2011

Multiple pathways for mitophagy: A neurodegenerative conundrum for Parkinson's disease.

scientific article published on 4 April 2018

Mutant LRRK2 elicits calcium imbalance and depletion of dendritic mitochondria in neurons

scientific article

Mutant LRRK2 enhances glutamatergic synapse activity and evokes excitotoxic dendrite degeneration

scientific article

NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy

journal article published in 2016

Nitrite activates protein kinase A in normoxia to mediate mitochondrial fusion and tolerance to ischaemia/reperfusion.

scientific article published on 30 September 2013

Occult germ cell tumour presenting as spontaneous intracerebral haemorrhage

scientific article published on 01 May 2007

Oxidative neuronal injury. The dark side of ERK1/2.

scientific article published on June 2004

PINK1 Interacts with VCP/p97 and Activates PKA to Promote NSFL1C/p47 Phosphorylation and Dendritic Arborization in Neurons

scientific article published on 10 January 2018

PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis.

scientific article

PINK1 regulates mitochondrial trafficking in dendrites of cortical neurons through mitochondrial PKA.

scientific article published on 30 May 2017

PKA Phosphorylation of NCLX Reverses Mitochondrial Calcium Overload and Depolarization, Promoting Survival of PINK1-Deficient Dopaminergic Neurons

scientific article published on 29 September 2015

Peroxiredoxin-2 protects against 6-hydroxydopamine-induced dopaminergic neurodegeneration via attenuation of the apoptosis signal-regulating kinase (ASK1) signaling cascade.

scientific article

Reactive oxygen/nitrogen species at the fulcrum of life–death decisions: A commentary on “Peroxynitrite transforms nerve growth factor into an apoptotic factor for motor neurons”

scientific article published on 23 September 2006

Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII) ⬇️

scientific article published on June 15, 1997

Regulation of the autophagy protein LC3 by phosphorylation

scientific article

Review: autophagy and neurodegeneration: survival at a cost?

scientific article

Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells

scientific article

Role of reactive oxygen species in extracellular signal-regulated protein kinase phosphorylation and 6-hydroxydopamine cytotoxicity.

scientific article published on February 2003

Small B-cell lymphoma presenting as diffuse dural thickening with cranial neuropathies

scientific article published in September 2002

Starving neurons show sex difference in autophagy.

scientific article

Sustained extracellular signal-regulated kinase activation by 6-hydroxydopamine: implications for Parkinson's disease

scientific article

Sympathetic ganglionic blockade masks beneficial effect of isoflurane on histologic outcome from near-complete forebrain ischemia in the rat.

scientific article published in March 1999

Synaptic dysfunction in genetic models of Parkinson's disease: a role for autophagy?

scientific article published on 20 October 2010

The aetiology in paediatric aphakic glaucoma

scientific article published on 11 November 2005

The effect of residue 1106 on the thioester-mediated covalent binding reaction of human complement protein C4 and the monomeric rat alpha-macroglobulin alpha 1 I3.

scientific article published on July 1995

The mitochondrial transcription factor TFAM in neurodegeneration: emerging evidence and mechanisms

scientific article published on 24 January 2018

The p75 neurotrophin receptor can induce autophagy and death of cerebellar Purkinje neurons.

scientific article published on May 2004

Tickled PINK1: mitochondrial homeostasis and autophagy in recessive Parkinsonism.

scientific article published on 09 July 2009

Ubiquitin immunochemistry as a diagnostic aid for community pathologists evaluating patients who have dementia

scientific article published in April 2000

α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson's disease

scientific article published on June 2016

α2‐Macroglobulin: A Sensor for Proteolysis ⬇️

scientific article published on September 10, 1994

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