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List of works by Anna Karlsson

1,2,3-Triazole-[2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D- ribofuranosyl]-3'-spiro-5"-(4"-amino-1",2"-oxathiole 2",2"-dioxide) (TSAO) analogues: synthesis and anti-HIV-1 activity

scientific article published on November 1994

2 cloning and expression of mouse deoxycytidine kinase. Pure recombinant mouse and human enzymes show differences in substrate specificity

scientific article published on September 1994

2',3'-Dideoxycytidine phosphorylation by recombinant mouse and human deoxycytidine kinase

scientific article published on 01 January 1994

2'-O-Acyl/alkyl-substituted arabinosyl nucleosides as inhibitors of human mitochondrial thymidine kinase

scientific article

3'-[4-Aryl-(1,2,3-triazol-1-yl)]-3'-deoxythymidine analogues as potent and selective inhibitors of human mitochondrial thymidine kinase

scientific article published on April 2010

5-Fluoro-2'-deoxyuridine has effects on mitochondria in CEM T-lymphoblast cells

scientific article

5‘-Phosphoramidates and 5‘-Diphosphates of 2‘-O-Allyl-β-d-arabinofuranosyl- uracil, -cytosine, and -adenine: Inhibition of Ribonucleotide Reductase

scientific article published on 01 August 1999

A monocyte-specific peptide from herpes simplex virus type 2 glycoprotein G activates the NADPH-oxidase but not chemotaxis through a G-protein-coupled receptor distinct from the members of the formyl peptide receptor family

scientific article published in November 2007

A proinflammatory peptide from herpes simplex virus type 2 glycoprotein G affects neutrophil, monocyte, and NK cell functions

scientific article published in February 2005

A prospective study of 115 initially asymptomatic HIV infected gay men in Stockholm, Sweden

scientific article published on 01 January 1991

A simple skin blister technique for the study of in vivo transmigration of human leukocytes

scientific article published on 06 April 2013

Ability of monocyte-derived dendritic cells to secrete oxygen radicals in response to formyl peptide receptor family agonists compared to that of myeloid and plasmacytoid dendritic cells

scientific article published on 10 January 2007

Activation of human neutrophils by mycobacterial phenolic glycolipids

scientific article published on 01 November 1999

Activation of the neutrophil nicotinamide adenine dinucleotide phosphate oxidase by galectin-1.

scientific article

Active site mutants of Drosophila melanogaster multisubstrate deoxyribonucleoside kinase

scientific article

Activity of various thiocarboxanilide derivatives against wild-type and several mutant human immunodeficiency virus type 1 strains.

scientific article published on June 1995

Acute cytotoxicity of arabinofuranosyl nucleoside analogs is not dependent on mitochondrial DNA.

scientific article

Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase.

scientific article

Affinity of galectin-8 and its carbohydrate recognition domains for ligands in solution and at the cell surface

scientific article published on 05 March 2007

Alterations of mitochondrial DNA in CEM cells selected for resistance toward ddC toxicity

scientific article published on January 2006

Altered deoxyribonucleotide pools in T-lymphoblastoid cells expressing the multisubstrate nucleoside kinase of Drosophila melanogaster

scientific article

An eleven year follow-up of delayed-type hypersensitivity testing for the identification of HIV-1 infected patients at increased risk of developing AIDS

scientific article published on 01 January 1996

Assembly and activation of the neutrophil NADPH oxidase in granule membranes

scientific article

Biological phenotypes of HIV-1 in pathogenesis and transmission

scientific article published on January 1994

Bystander effects of cancer cell lines transduced with the multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster and synergistic enhancement by hydroxyurea

scientific article

Bystander effects of nucleoside analogs phosphorylated in the cytosol or mitochondria

scientific article

CFP-10 from Mycobacterium tuberculosis selectively activates human neutrophils through a pertussis toxin-sensitive chemotactic receptor

scientific article published on 20 October 2014

Capacitative Ca2+ influx and activation of the neutrophil respiratory burst. Different regulation of plasma membrane- and granule-localized NADPH-oxidase.

scientific article

Certain human Gp120-HIV antibodies react with anti-CD4 antibodies

scientific article published on 01 January 1988

Challenging the opinion that SAPHO syndrome is associated with low intracellular ROS production in neutrophils

scientific article published on 28 September 2015

Changes in activation states of murine polymorphonuclear leukocytes (PMN) during inflammation: a comparison of bone marrow and peritoneal exudate PMN.

scientific article

Changes in the ratio between FPR and FPRL1 triggered superoxide production in human neutrophils-a tool in analysing receptor specific events

scientific article published on 10 December 2007

Characteristics of the Pro225His mutation in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase that appears under selective pressure of dose-escalating quinoxaline treatment of HIV-1

scientific article

ChemInform Abstract: Design, Synthesis and Enzymatic Activity of Highly Selective Human Mitochondrial Thymidine Kinase Inhibitors

Cloning and characterization of the multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster

scientific article published in August 1999

Cloning and expression of human deoxyguanosine kinase cDNA

scientific article

Cloning of mouse mitochondrial thymidine kinase 2 cDNA

scientific journal article

Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2

scientific article

Collection of in vivo transmigrated neutrophils from human skin

scientific article published on January 2014

Comparison of sample preparation methods for the high-performance liquid chromatographic analysis of cell culture extracts for triphosphate ribonucleosides and deoxyribonucleosides.

scientific article published on February 1987

Concomitant combination therapy for HIV infection preferable over sequential therapy with 3TC and non-nucleoside reverse transcriptase inhibitors

scientific article published on November 1996

Conserved gene structure and transcription factor sites in the human and mouse deoxycytidine kinase genes

scientific article

Cord blood neutrophils display a galectin-3 responsive phenotype accentuated by vaginal delivery

scientific article

Coupling between Catalysis and Oligomeric Structure in Nucleoside Diphosphate Kinase

scientific article published on 20 February 1998

Cultured rat and purified human Pneumocystis carinii stimulate intra- but not extracellular free radical production in human neutrophils

scientific article published on September 1998

Cytochalasin B triggers a novel pertussis toxin sensitive pathway in TNF-alpha primed neutrophils

scientific article

Cytosolic and mitochondrial deoxyribonucleotidases: activity with substrate analogs, inhibitors and implications for therapy

scientific article published on August 2003

Decreased thymidine kinase levels in peripheral blood cells from HIV-seropositive individuals: implications for zidovudine metabolism.

scientific article published in July 1995

Depletion of mitochondrial DNA by down-regulation of deoxyguanosine kinase expression in non-proliferating HeLa cells

scientific article

Desensitization of formyl peptide receptors is abolished in calcium ionophore-primed neutrophils: an association of the ligand-receptor complex to the cytoskeleton is not required for a rapid termination of the NADPH-oxidase response

scientific article published on 01 March 1998

Desensitization of the fMLP-induced NADPH-oxidase response in human neutrophils is lacking in okadaic acid-treated cells

scientific article published on 01 June 1997

Design, synthesis and biological evaluation of 2'-deoxy-2',2'-difluoro-5-halouridine phosphoramidate ProTides

scientific article published on 27 May 2011

Design, synthesis and enzymatic activity of highly selective human mitochondrial thymidine kinase inhibitors.

scientific article published in May 2001

Detection of glycoprotein receptors on blotting membranes by binding of live bacteria and amplification by growth

scientific article published on 01 January 1995

Differences in kinetic properties of pure recombinant human and mouse deoxycytidine kinase.

scientific article

Different glycosphingolipid composition in human neutrophil subcellular compartments

scientific article

Different subcellular localization of cytochrome b and the dormant NADPH-oxidase in neutrophils and macrophages: effect on the production of reactive oxygen species during phagocytosis.

scientific article published on March 1995

Differential incorporation of 1-beta-D-arabinofuranosylcytosine and 9-beta-D-arabinofuranosylguanine into nuclear and mitochondrial DNA.

scientific article

Differential intracellular compartmentalization of herpetic thymidine kinases (TKs) in TK gene-transfected tumor cells: molecular characterization of the nuclear localization signal of herpes simplex virus type 1 TK.

scientific article published on December 1998

Divergent effects on phagocytosis by macrophage-derived oxygen radicals

scientific article published on 14 August 2009

Dual effect of interleukin 4 on HIV-1 expression: Implications for viral phenotypic switch and disease progression ⬇️

scientific article published on July 21, 1998

Dual mechanisms of 9-beta-D-arabinofuranosylguanine resistance in CEM T-lymphoblast leukemia cells

scientific article published in July 2001

Effects of 9-beta-D-arabinofuranosylguanine on mitochondria in CEM T-lymphoblast leukemia cells

scientific article published in August 2003

Eicar (5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide). A novel potent inhibitor of inosinate dehydrogenase activity and guanylate biosynthesis

scientific article

Elevated Mitochondrial Reactive Oxygen Species and Cellular Redox Imbalance in Human NADPH-Oxidase-Deficient Phagocytes

scientific article published on 21 December 2017

Endogenous Acute Phase Serum Amyloid A Lacks Pro-Inflammatory Activity, Contrasting the Two Recombinant Variants That Activate Human Neutrophils through Different Receptors

scientific article

Engineering of a single conserved amino acid residue of herpes simplex virus type 1 thymidine kinase allows a predominant shift from pyrimidine to purine nucleoside phosphorylation

scientific article published on 15 May 2006

Enhanced cytotoxicity of nucleoside analogs by overexpression of mitochondrial deoxyguanosine kinase in cancer cell lines

scientific article published in June 1998

Enhanced toxicity of purine nucleoside analogs in cells expressing Drosophila melanogaster nucleoside kinase mutants

scientific article published on 3 August 2006

Escherichia coli-induced activation of neutrophil NADPH-oxidase: lipopolysaccharide and formylated peptides act synergistically to induce release of reactive oxygen metabolites

scientific article

Evidence of an intact N-terminal translocation sequence of human mitochondrial adenylate kinase 4

scientific article

Exploitation of the low fidelity of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase and the nucleotide composition bias in the HIV-1 genome to alter the drug resistance development of HIV.

scientific article published on July 2001

From uncertainty to gradually managing and awaiting recovery of a periodic condition- a qualitative study of parents´ experiences of PFAPA syndrome

Galectin-3 activates the NADPH-oxidase in exudated but not peripheral blood neutrophils ⬇️

scientific article published on 01 May 1998

Galectin-3 enhances monocyte-derived macrophage efferocytosis of apoptotic granulocytes in asthma

Galectin-3 functions as an opsonin and enhances the macrophage clearance of apoptotic neutrophils

scientific article

Galectin-3 type-C self-association on neutrophil surfaces; The carbohydrate recognition domain regulates cell function

scientific article published on 10 January 2018

Galectins as inflammatory mediators

scientific article published on January 2004

Gene expression deregulation in postnatal skeletal muscle of TK2 deficient mice reveals a lower pool of proliferating myogenic progenitor cells

scientific article

Group Specific Component and Susceptibility to HIV Infection and Progression to AIDS ⬇️

scientific article published on 01 January 1988

HIV-1-specific reverse transcriptase inhibitors show differential activity against HIV-1 mutant strains containing different amino acid substitutions in the reverse transcriptase

scientific article published on January 1993

Hematopoiesis in the thymidine kinase 2 deficient mouse model of mitochondrial DNA depletion syndrome

scientific article published on 4 May 2010

Highly favorable antiviral activity and resistance profile of the novel thiocarboxanilide pentenyloxy ether derivatives UC-781 and UC-82 as inhibitors of human immunodeficiency virus type 1 replication

scientific article published on August 1996

Host defense peptide LL-37 selectively reduces proinflammatory macrophage responses.

scientific article

Human UMP-CMP kinase 2, a novel nucleoside monophosphate kinase localized in mitochondria

scientific article

Human deoxycytidine kinase is located in the cell nucleus

scientific article

Human immunodeficiency virus 1 (HIV-1)-specific reverse transcriptase (RT) inhibitors may suppress the replication of specific drug-resistant (E138K)RT HIV-1 mutants or select for highly resistant (Y181C-->C181I)RT HIV-1 mutants

scientific article published on 5 July 1994

Human immunodeficiency virus type 1 drug-resistance patterns with different 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives.

scientific article published on October 1993

Human immunodeficiency virus type 1-specific [2',5'-bis-O-(tert- butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5"-(4"-amino-1",2"- oxathiole-2",2"-dioxide)-purine analogues show a resistance spectrum that is different from that of the human imm

scientific article published on January 1993

Human mitochondrial pyrophosphatase: cDNA cloning and analysis of the gene in patients with mtDNA depletion syndromes.

scientific article published on 21 November 2005

Human mitochondrial thymidine kinase is selectively inhibited by 3'-thiourea derivatives of beta-thymidine: identification of residues crucial for both inhibition and catalytic activity

scientific article published on 20 February 2009

Hydroxyurea increases the phosphorylation of 3'-fluorothymidine and 3'-azidothymidine in CEM cells

scientific article published on December 1989

Identification of CD66a and CD66b as the major galectin-3 receptor candidates in human neutrophils

scientific article (publication date: 15 November 1999)

Identification of a novel human adenylate kinase. cDNA cloning, expression analysis, chromosome localization and characterization of the recombinant protein

scientific article

Identification of genes associated to 2',2'-difluorodeoxycytidine resistance in HeLa cells with a lentiviral short-hairpin RNA library

scientific article

Identification of the lysosomal membrane glycoprotein Lamp-1 as a receptor for type-1-fimbriated (mannose-specific) Escherichia coli.

scientific article

Identification of two active functional domains of human adenylate kinase 5.

scientific article published on 3 August 2009

Immunostimulatory DNA induces degranulation and NADPH-oxidase activation in human neutrophils while concomitantly inhibiting chemotaxis and phagocytosis

scientific article published in October 2002

Immunostimulatory oligodeoxynucleotides induce dolphin neutrophil NADPH-oxidase activation in a CpG-independent but phosphorothioate backbone-dependent manner

scientific article published on 13 January 2005

Improving the selectivity of acyclic nucleoside analogues as inhibitors of human mitochondrial thymidine kinase: replacement of a triphenylmethoxy moiety with substituted amines and carboxamides

scientific article published in September 2003

Incorporation of nucleoside analogs into nuclear or mitochondrial DNA is determined by the intracellular phosphorylation site

scientific article published on 01 September 2000

Increased intracellular oxygen radical production in neutrophils during febrile episodes of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome

scientific article published on November 2013

Increased mitochondrial DNA copy-number in CEM cells resistant to delayed toxicity of 2',3'-dideoxycytidine

scientific article published on 15 December 2007

Influence of acyclovir and bucyclovir on nucleotide pools in cells infected with herpes simplex virus type 1.

scientific article

Inhibition of glutamate oxaloacetate transaminase 1 in cancer cell lines results in altered metabolism with increased dependency of glucose.

scientific article

Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells

scientific article

Inhibition of phospholipase A(2) abrogates intracellular processing of NADPH-oxidase derived reactive oxygen species in human neutrophils.

scientific article published on 27 December 2012

Interleukin-8-derived peptide has antibacterial activity

scientific article published on September 2005

Interplay of HIV-1 phenotype and neutralizing antibody response in pathogenesis of AIDS

article

Intracellular generation of superoxide by the phagocyte NADPH oxidase: how, where, and what for?

scientific article published on 24 September 2010

Intracellular metabolism of the N7-substituted acyclic nucleoside analog 2-amino-7-(1,3-dihydroxy-2-propoxymethyl)purine, a potent inhibitor of herpesvirus replication.

scientific article

Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway

scientific article published on 24 June 2012

Investigation of the substrate recognition of Drosophila melanogaster nucleoside kinase by site directed mutagenesis

scientific article published in October 2004

Ionomycin-induced neutrophil NADPH oxidase activity is selectively inhibited by the serine protease inhibitor diisopropyl fluorophosphate

scientific article

Is trichloroacetic acid an insufficient sample quencher of redox reactions?

scientific article

Knocking-out concentrations of HIV-1-specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virus.

scientific article published on October 1993

Lack of correlation between NADPH-oxidase priming and elevated alkaline phosphatase activity in cord blood neutrophils

scientific article published on 01 August 1995

Late-onset respiratory failure due to TK2 mutations causing multiple mtDNA deletions.

scientific article

Ligand recognition and activation of formyl peptide receptors in neutrophils

scientific article

Lipid raft proteome of the human neutrophil azurophil granule

scientific article published in January 2007

Lipid-mediated protein delivery of suicide nucleoside kinases

scientific article published on October 2003

Lipopolysaccharide-induced gelatinase granule mobilization primes neutrophils for activation by galectin-3 and formylmethionyl-Leu-Phe

scientific article published on February 2001

Lipopolysaccharide-induced granule mobilization and priming of the neutrophil response to Helicobacter pylori peptide Hp(2-20), which activates formyl peptide receptor-like 1.

scientific article

Localization of the human deoxyguanosine kinase gene (DGUOK) to chromosome 2p13

scientific article

Long term expression of Drosophila melanogaster nucleoside kinase in thymidine kinase 2-deficient mice with no lethal effects caused by nucleotide pool imbalances

scientific article

Loss of thymidine kinase 2 alters neuronal bioenergetics and leads to neurodegeneration.

scientific article published on February 2010

MPO deficiency confers impaired processing of neutrophil reactive oxygen species in a patient with severe CRMO.

scientific article

Mammalian 5'(3')-deoxyribonucleotidase, cDNA cloning, and overexpression of the enzyme in Escherichia coli and mammalian cells

scientific article

Marked inhibitory activity of non-nucleoside reverse transcriptase inhibitors against human immunodeficiency virus type 1 when combined with (-)2',3'-dideoxy-3'-thiacytidine

scientific article published on May 1996

Measurement of respiratory burst products generated by professional phagocytes

scientific article published in January 2007

Measurement of respiratory burst products, released or retained, during activation of professional phagocytes

scientific article published in January 2014

Mechanism of anti-HIV action of masked alaninyl d4T-MP derivatives

scientific article

Mitochondrial expression of the Drosophila melanogaster multisubstrate deoxyribonucleoside kinase

scientific article published on 12 September 2007

Mutational tuning of galectin-3 specificity and biological function

scientific article

N1-Substituted Thymine Derivatives as Mitochondrial Thymidine Kinase (TK-2) Inhibitors

scientific article published on 01 December 2006

NADPH-oxidase activation in murine neutrophils via formyl peptide receptors

scientific article published in January 2003

Nelarabine: a new purine analog in the treatment of hematologic malignancies.

scientific article

Neutrophil NET formation is regulated from the inside by myeloperoxidase-processed reactive oxygen species

scientific article

Neutrophil alkaline phosphatase activity increase in bacterial infections is not associated with a general increase in secretory vesicle membrane components.

scientific article

Neutrophil secretion induced by an intracellular Ca2+ rise and followed by whole-cell patch-clamp recordings occurs without any selective mobilization of different granule populations

scientific article published on January 2006

Neutrophil secretory vesicles are the intracellular reservoir for GPI-80, a protein with adhesion-regulating potential

scientific article

Neutrophils from patients with SAPHO syndrome show no signs of aberrant NADPH oxidase-dependent production of intracellular reactive oxygen species

scientific article published on 27 April 2016

New ultrasensitive 32P-postlabelling method for the analysis of 3,N4-etheno-2'-deoxycytidine in human urine

scientific article published in July 2006

Newcastle disease virus neuraminidase primes neutrophils for stimulation by galectin-3 and formyl-Met-Leu-Phe

scientific article published in August 2004

Non-nucleoside inhibitors of mitochondrial thymidine kinase (TK-2) differentially inhibit the closely related herpes simplex virus type 1 TK and Drosophila melanogaster multifunctional deoxynucleoside kinase

scientific article published in February 2003

Novel ribofuranosylnucleoside lead compounds for potent and selective inhibitors of mitochondrial thymidine kinase-2

scientific article

Novel selective human mitochondrial kinase inhibitors: design, synthesis and enzymatic activity

scientific article

Nucleoside analog cytotoxicity and bystander cell killing of cancer cells expressing Drosophila melanogaster deoxyribonucleoside kinase in the nucleus or cytosol

scientific article

Nucleoside diphosphate kinase. Investigation of the intersubunit contacts by site-directed mutagenesis and crystallography

scientific article

Nucleotide affinity for a stable phosphorylated intermediate of nucleoside diphosphate kinase

scientific article

On the road to discovery in periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome ⬇️

scientific article published on August 2, 2011

Oral candida albicans in HIV infection

scientific article published on 01 January 1987

P02-025 - Homozygous Q705K sequence variant in NLRP3.

scientific article

P2Y2 receptor signaling in neutrophils is regulated from inside by a novel cytoskeleton-dependent mechanism

scientific article published on 17 July 2015

PW03-003 – Altered neutrophil function in PFAPA.

scientific article

Pediatric chronic non-bacterial osteomyelitis in Goteborg, Sweden.

scientific article

Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1/LXA4R, is not affected by lipoxin A4

scientific article (publication date: November 2002)

Phagocyte interactions with Mycobacterium tuberculosis--Simultaneous analysis of phagocytosis, phagosome maturation and intracellular replication by imaging flow cytometry

scientific article published on 14 October 2015

Phagocytosis following translocation of the neutrophil b-cytochrome from the specific granule to the plasma membrane is associated with an increased leakage of reactive oxygen species

scientific article published on 01 December 1992

Phenol-Soluble Modulin α Peptide Toxins from Aggressive Staphylococcus aureus Induce Rapid Formation of Neutrophil Extracellular Traps through a Reactive Oxygen Species-Independent Pathway

scientific article published on 9 March 2017

Phosphorylation of 9-beta-D-arabinofuranosylguanine monophosphate by Drosophila melanogaster guanylate kinase

scientific article published in October 2005

Phosphorylation of anticancer nucleoside analogs by human mitochondrial deoxyguanosine kinase

scientific article published in October 1998

Phosphorylation of deoxycytidine analog monophosphates by UMP-CMP kinase: molecular characterization of the human enzyme

scientific article

Phosphorylation of nucleosides and nucleoside analogs by mammalian nucleoside monophosphate kinases

scientific article (publication date: 2000)

Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases

scientific journal article

Potent antitumoral effects of targeted promoter-driven oncolytic adenovirus armed with Dm-dNK for breast cancer in vitro and in vivo

scientific article

Priming of human neutrophils by mycobacterial lipoarabinomannans: role of granule mobilisation

scientific article published in November 2001

Progressive loss of mitochondrial DNA in thymidine kinase 2-deficient mice

scientific journal article

Proinflammatory activity of a cecropin-like antibacterial peptide from Helicobacter pylori

scientific article

Properties and levels of deoxynucleoside kinases in normal and tumor cells; implications for chemotherapy

scientific article published in January 1994

Quantification of heterotypic granule fusion in human neutrophils by imaging flow cytometry

scientific article

Reactivation of desensitized formyl peptide receptors by platelet activating factor: a novel receptor cross talk mechanism regulating neutrophil superoxide anion production

scientific article

Reactivation of formyl peptide receptors triggers the neutrophil NADPH-oxidase but not a transient rise in intracellular calcium

scientific article published on 28 May 2003

Recent advances in thymidine kinase 2 (TK2) inhibitors and new perspectives for potential applications

scientific article published on January 2012

Reduced levels of mitochondrial DNA increases the toxicity of 9-beta-D-arabinofuranosylguanine (araG).

scientific article published in June 2008

Regulation of interleukin-4 signaling by extracellular reduction of intramolecular disulfides

scientific article published on 28 October 2009

Regulation of neutrophil apoptosis differs after in vivo transmigration to skin chambers and synovial fluid: a role for inflammasome-dependent interleukin-1β release.

scientific article published on 5 April 2013

Replicative capacity of human immunodeficiency virus from patients with varying severity of HIV infection

scientific article published in September 1986

Resistance pattern of human immunodeficiency virus type 1 reverse transcriptase to quinoxaline S-2720

scientific article

Respiratory burst in human neutrophils

scientific article

Restriction and enhancement of human immunodeficiency virus type 1 replication by modulation of intracellular deoxynucleoside triphosphate pools.

scientific article published on January 1994

Retained sensitivity to cytotoxic pyrimidine nucleoside analogs in thymidine kinase 2 deficient human fibroblasts

scientific article published on January 2010

Retroviral transduction of cancer cell lines with the gene encoding Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.

scientific article published on December 2000

Retrovirus-mediated Drosophila melanogaster multisubstrate deoxyribonucleoside kinase gene therapy of gastric cancer cells in vitro and in vivo.

scientific article published on July 2010

Reverse transcriptase fidelity and HIV-1 variation

scientific article published on 10 January 1997

Review of autoinflammatory diseases, with a special focus on periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome

scientific article

Secretion of type-1-fimbriae binding proteins from human neutrophil granulocytes.

scientific article

Sensitivity of (138 Glu-->Lys) mutated human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) to HIV-1-specific RT inhibitors

scientific article

Sensitivity to inhibition by beta-chemokines correlates with biological phenotypes of primary HIV-1 isolates

scientific article published on December 1996

Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor like-1.

scientific article published on 5 November 2007

Severe chronic non-bacterial osteomyelitis associated with MPO deficiency

scientific article

Structure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug design

scientific article

Substrate specificity and phosphorylation of antiviral and anticancer nucleoside analogues by human deoxyribonucleoside kinases and ribonucleoside kinases

scientific journal article

Substrate specificity of feline and canine herpesvirus thymidine kinase

scientific article

Substrate specificity of mitochondrial 2'-deoxyguanosine kinase. Efficient phosphorylation of 2-chlorodeoxyadenosine

scientific article published on 25 October 1993

Substrate specificity of three viral thymidine kinases (TK): vaccinia virus TK, feline herpesvirus TK, and canine herpesvirus TK.

scientific article published in January 2006

Suppression of the breakthrough of human immunodeficiency virus type 1 (HIV-1) in cell culture by thiocarboxanilide derivatives when used individually or in combination with other HIV-1-specific inhibitors (i.e., TSAO derivatives)

scientific article

Surface-related triggering of the neutrophil respiratory burst. Characterization of the response induced by IgG adsorbed to hydrophilic and hydrophobic glass surfaces

scientific article published on 01 July 1997

Synthesis and Comparative Molecular Field Analysis (CoMFA) of Symmetric and Nonsymmetric Cyclic Sulfamide HIV-1 Protease Inhibitors

article

Synthesis and comparative molecular field analysis (CoMFA) of symmetric and nonsymmetric cyclic sulfamide HIV-1 protease inhibitors

scientific article

Synthesis and evaluation of thymine-derived carboxamides against mitochondrial thymidine kinase (TK-2) and related enzymes

scientific article published in October 2004

Synthesis, Cytostatic Activity and Inhibition of Ribonucleotide Reductase by 5′-Phosphoramidates and 5′-Diphosphates, of 2′-O-Allyl-arabinofuranosyl Nucleosides

scientific article published on 01 April 1999

Synthesis, modeling and evaluation of 3'-(1-aryl-1H-tetrazol-5-ylamino)-substituted 3'-deoxythymidine derivatives as potent and selective human mitochondrial thymidine kinase inhibitors

scientific article published on 2 December 2010

TSAO Derivatives: Highly Specific Inhibitors of Human Immunodeficiency Virus Type-1 (HIV-1) Replication

article

Tanshinone IIA enhances bystander cell killing of cancer cells expressing Drosophila melanogaster deoxyribonucleoside kinase in nuclei and mitochondria

scientific article

The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition

scientific article

The Drosophila melanogaster UMP-CMP kinase cDNA encodes an N-terminal mitochondrial import signal

scientific article published on November 2003

The HIV replication inhibitor 3'-fluoro-3'-deoxythymidine blocks sialylation of N-linked oligosaccharides

scientific article

The Lipidated Peptidomimetic Lau-((S)-Aoc)-(Lys-βNphe)6-NH2 Is a Novel Formyl Peptide Receptor 2 Agonist That Activates Both Human and Mouse Neutrophil NADPH Oxidase

scientific article published on 15 July 2016

The beta-galactoside binding immunomodulatory lectin galectin-3 reverses the desensitized state induced in neutrophils by the chemotactic peptide f-Met-Leu-Phe: role of reactive oxygen species generated by the NADPH-oxidase and inactivation of the a

scientific article published on 25 August 2008

The characterization of human adenylate kinases 7 and 8 demonstrates differences in kinetic parameters and structural organization among the family of adenylate kinase isoenzymes

scientific article

The effect of a methyl or 2-fluoroethyl substituent at the N-3 position of thymidine, 3'-fluoro-3'-deoxythymidine and 1-beta-D-arabinosylthymine on their antiviral and cytostatic activity in cell culture

scientific article

The human adenylate kinase 9 is a nucleoside mono- and diphosphate kinase

scientific article

The human neutrophil subsets defined by the presence or absence of OLFM4 both transmigrate into tissue in vivo and give rise to distinct NETs in vitro

scientific article

The human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinase

scientific article

The leukocyte chemotactic receptor FPR2, but not the closely related FPR1, is sensitive to cell-penetrating pepducins with amino acid sequences descending from the third intracellular receptor loop

scientific article published on 2 April 2013

The lysosomal membrane glycoproteins Lamp-1 and Lamp-2 are present in mobilizable organelles, but are absent from the azurophil granules of human neutrophils

scientific article

The many isoforms of human adenylate kinases

scientific article published on 2 February 2014

The mechanism for activation of the neutrophil NADPH-oxidase by the peptides formyl-Met-Leu-Phe and Trp-Lys-Tyr-Met-Val-Met differs from that for interleukin-8.

scientific article

The mitochondrial carrier SLC25A10 regulates cancer cell growth

scientific article

The multifunctional deoxynucleoside kinase of insect cells is a target for the development of new insecticides

scientific article published in April 2000

The multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster as a therapeutic suicide gene of breast cancer cells

scientific article published on June 2011

The phagocyte chemiluminescence paradox: luminol can act as an inhibitor of neutrophil NADPH-oxidase activity

scientific article

The phenylmethylthiazolylthiourea nonnucleoside reverse transcriptase (RT) inhibitor MSK-076 selects for a resistance mutation in the active site of human immunodeficiency virus type 2 RT.

scientific article

The presence of stomatin in detergent-insoluble domains of neutrophil granule membranes

scientific article

The subcellular location of nucleoside analog phosphorylation is a determinant of synergistic effects of hydroxyurea.

scientific article published on September 2000

The synthetic chemoattractant Trp-Lys-Tyr-Met-Val-DMet activates neutrophils preferentially through the lipoxin A(4) receptor

scientific article published on 01 March 2000

The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2

scientific article (publication date: 15 June 2001)

The two neutrophil members of the formylpeptide receptor family activate the NADPH-oxidase through signals that differ in sensitivity to a gelsolin derived phosphoinositide-binding peptide

scientific article

Thioredoxin-1 and protein disulfide isomerase catalyze the reduction of similar disulfides in HIV gp120.

scientific article published on 3 January 2012

Thymidine kinase 2 deficiency-induced mtDNA depletion in mouse liver leads to defect β-oxidation

scientific article

Toward an Inclusive, Congruent, and Precise Definition of Autoinflammatory Diseases

scientific article

Transgene expression of Drosophila melanogaster nucleoside kinase reverses mitochondrial thymidine kinase 2 deficiency

scientific article published on 3 January 2013

Treatment of human immunodeficiency virus type 1 (HIV-1)-infected cells with combinations of HIV-1-specific inhibitors results in a different resistance pattern than does treatment with single-drug therapy.

scientific article published on September 1993

Two novel mutations in thymidine kinase-2 cause early onset fatal encephalomyopathy and severe mtDNA depletion

scientific article published on 18 January 2010

Uric acid, a nucleic acid degradation product, down-regulates dsRNA-triggered arthritis

scientific article published on 30 December 2005

[Familial Mediterranean fever – an important disease in a globalised world].

scientific article published on 22 August 2016

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