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List of works by Christian Thiede

188Re anti-CD66 radioimmunotherapy combined with reduced-intensity conditioning and in-vivo T cell depletion in elderly patients undergoing allogeneic haematopoietic cell transplantation

scientific article published on 7 December 2009

A highly sensitive method for the detection of PKC412 (CGP41251) and its metabolites by high-performance liquid chromatography

scientific article published on 23 February 2007

A novel prognostic model in elderly patients with acute myeloid leukemia: results of 909 patients entered into the prospective AML96 trial

scientific article published on 4 May 2010

A one-mutation mathematical model can explain the age incidence of acute myeloid leukemia with mutated nucleophosmin (NPM1).

scientific article

A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemia

scientific article

ACTR-52. CLINICAL IMPACT OF PROMOTER DETECTION IN CIRCULATING CELL-FREE DNA OF PATIENTS WITH GLIOBLASTOMA – A PILOT STUDY

Aberrant methylation of the M-type phospholipase A(2) receptor gene in leukemic cells

scientific article

Abnormal localization and accumulation of FLT3-ITD, a mutant receptor tyrosine kinase involved in leukemogenesis

scientific article

Activation of the RAS pathway is predictive for a chemosensitive phenotype of acute myelogenous leukemia blasts

scientific article published in May 2005

Activity of sirolimus in patients with myelodysplastic syndrome--results of a pilot study.

scientific article

Acute heart failure after allogeneic blood stem cell transplantation due to massive myocardial infiltration by cytotoxic T cells of donor origin.

scientific article published on January 2001

Acute myeloid leukemia in the elderly is characterized by a distinct genetic and epigenetic landscape

scientific article

Acute myeloid leukemia with deletion 9q within a noncomplex karyotype is associated with CEBPA loss-of-function mutations

scientific article published on 01 April 2005

Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2, randomised controlled trial

scientific article

Adenoviral p53 gene transfer and gemcitabine in three patients with liver metastases due to advanced pancreatic carcinoma

scientific article

Age-dependent frequencies of NPM1 mutations and FLT3-ITD in patients with normal karyotype AML (NK-AML).

scientific article

Allogeneic Hematopoietic Cell Transplantation in Multiple Myeloma: Focus on Longitudinal Assessment of Donor Chimerism, Extramedullary Disease, and High-Risk Cytogenetic Features

scientific article published on 30 August 2016

Allogeneic Stem Cell Transplantation Improves Survival in Patients with Acute Myeloid Leukemia Characterized by a High Allelic Ratio of Mutant FLT3-ITD.

scientific article published on 6 November 2015

Allogeneic hematopoietic cell transplantation improves outcome of adults with t(6;9) acute myeloid leukemia: results from an international collaborative study

scientific article published on 19 April 2019

Allogeneic hematopoietic cell transplantation in intermediate risk acute myeloid leukemia negative for FLT3-ITD, NPM1- or biallelic CEBPA mutations

scientific article published in September 2017

Allogeneic stem-cell transplantation in patients with NPM1-mutated acute myeloid leukemia: results from a prospective donor versus no-donor analysis of patients after upfront HLA typing within the SAL-AML 2003 trial

scientific article

Allogeneic transplantation after reduced conditioning in high risk patients is complicated by a high incidence of acute and chronic graft-versus-host disease

scientific article published on March 2002

An optimized targeted Next-Generation Sequencing approach for sensitive detection of single nucleotide variants.

scientific article published on 9 January 2018

An unusual course of low-malignancy non-Hodgkin lymphoma of the stomach

scientific article published in July 1998

Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis

scientific article

Anchoring of FLT3 in the endoplasmic reticulum alters signaling quality

scientific article

Are lymphocytic monoclonality and immunoglobulin heavy chain (IgH) rearrangement premalignant conditions in chronic gastritis?

scientific article published on 01 June 2001

Association of Oesophageal Varices and Splanchnic Vein Thromboses in Patients with JAK2-Positive Myeloproliferative Neoplasms: Presentation of Two Cases and Data from a Retrospective Analysis

scientific article

Association of the EGF-TM7 receptor CD97 expression with FLT3-ITD in acute myeloid leukemia

scientific article published on 07 October 2015

Association with the single-nucleotide polymorphism (Glu785Lys) of the granulocyte colony-stimulating factor receptor with myelodysplastic syndromes and acute myeloid leukemia with multlineage dysplasia

scientific article published on 05 October 2006

Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDH-like DNA hypermethylation

scientific article published in Nature

Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation

scientific article published in Nature

Autotaxin is expressed in FLT3-ITD positive acute myeloid leukemia and hematopoietic stem cells and promotes cell migration and proliferation

scientific article published on 30 January 2013

Azacitidine combined with the selective FLT3 kinase inhibitor crenolanib disrupts stromal protection and inhibits expansion of residual leukemia-initiating cells in FLT3-ITD AML with concurrent epigenetic mutations

scientific article

Azacitidine for treatment of imminent relapse in MDS or AML patients after allogeneic HSCT: results of the RELAZA trial.

scientific article published on 2 September 2011

Azacitidine in combination with intensive induction chemotherapy in older patients with acute myeloid leukemia: The AML-AZA trial of the Study Alliance Leukemia.

scientific article published on 2 November 2015

Azacytidine impairs NK cell activity in AML and MDS patients undergoing MRD-based pre-emptive treatment after allogeneic stem cell transplantation

scientific article published on 30 August 2013

B-cell monoclonality is associated with lymphoid follicles in gastritis

scientific article

BAALC expression and FLT3 internal tandem duplication mutations in acute myeloid leukemia patients with normal cytogenetics: prognostic implications

scientific article published on 17 January 2006

BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation

scientific article published on 8 November 2017

Befundinterpretation der molekularen Diagnostik in der Verlaufskontrolle der chronischen myeloischen Leukämie: Empfehlungen einer deutschen Expertengruppe/Interpretation of molecular diagnostics results in routine monitoring for chronic myeloid leuk

Buccal swabs but not mouthwash samples can be used to obtain pretransplant DNA fingerprints from recipients of allogeneic bone marrow transplants

scientific article published on 01 March 2000

CD34+ cell dose, conditioning regimen and prior chemotherapy: factors with significant impact on the early kinetics of donor chimerism after allogeneic hematopoietic cell transplantation

scientific article published on 01 December 2004

CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice

scientific article published on 15 July 2010

CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia

scientific article published on 07 March 2022

Can prognostic scoring systems for chronic myeloid leukemia as established in adults be applied to pediatric patients?

scientific article published on 19 April 2015

Changes in cytogenetics and molecular genetics in acute myeloid leukemia from childhood to adult age groups

scientific article

Characteristics and outcome of patients with therapy-related acute promyelocytic leukemia front-line treated with or without arsenic trioxide

scientific article published on 21 March 2017

Characterization of acute myeloid leukemia with del(9q) - Impact of the genes in the minimally deleted region

scientific article published on 17 November 2018

Chimerism analysis after allogeneic stem cell transplantation.

scientific article

Chromosomal Abnormalities and Prognosis in NPM1-Mutated Acute Myeloid Leukemia: A Pooled Analysis of Individual Patient Data From Nine International Cohorts

scientific article published on 20 August 2019

Class I HDAC SNP analysis in healthy donors compared to AML patients

scientific article published on 05 April 2007

Clinical Challenges and Consequences of Measurable Residual Disease in Non-APL Acute Myeloid Leukemia

scientific article published on 23 October 2019

Clinical and functional implications of microRNA mutations in a cohort of 935 patients with myelodysplastic syndromes and acute myeloid leukemia

scientific article published on 31 December 2014

Clinical impact of KMT2C and SPRY4 expression levels in intensively treated younger adult acute myeloid leukemia patients

scientific article published on 22 September 2017

Clinical, molecular, and immunological responses to pembrolizumab treatment of synchronous melanoma and acute myeloid leukemia

article

Clofarabine salvage therapy before allogeneic hematopoietic stem cell transplantation in patients with relapsed or refractory AML: results of the BRIDGE trial.

scientific article published on 18 August 2015

Clonal architecture of del(5q) myelodysplastic syndromes: aberrant CD5 or CD7 expression within the myeloid progenitor compartment defines a subset with high clonal burden

scientific article published on 24 June 2015

Clonal evolution including partial loss of human leukocyte antigen genes favoring extramedullary acute myeloid leukemia relapse after matched related allogeneic hematopoietic stem cell transplantation

scientific article published on 01 April 2012

Colonic mucosal proliferation is related to serum deoxycholic acid levels

scientific article published in April 1999

Comparative analysis of MLL partial tandem duplication and FLT3 internal tandem duplication mutations in 956 adult patients with acute myeloid leukemia

scientific article published in July 2003

Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients.

scientific article

Comparison of spectral karyotyping and conventional cytogenetics in 39 patients with acute myeloid leukemia and myelodysplastic syndrome

scientific article published on 01 June 2000

Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: a web-based application for prediction of outcomes

scientific article published on 3 December 2010

Complete remission of primary high-grade B-cell gastric lymphoma after cure of Helicobacter pylori infection

scientific article published in April 2001

Concurrent JAK2(V617F) mutation and BCR-ABL translocation within committed myeloid progenitors in myelofibrosis

scientific article published on 03 May 2007

Conditioning with fludarabine and targeted busulfan for transplantation of allogeneic hematopoietic stem cells

scientific article published on 3 April 2003

Correction of complete interferon-gamma receptor 1 deficiency by bone marrow transplantation

scientific article (publication date: December 2002)

Cup-like acute myeloid leukemia: new disease or artificial phenomenon?

scientific article published on 26 January 2008

Cure of Helicobacter pylori infection and duration of remission of low-grade gastric mucosa-associated lymphoid tissue lymphoma

scientific article published on 01 September 1997

Cyclic severe elevated procalcitonin serum levels in a patient with post polycythemic myelofibrosis carrying a V617F-JAK2 mutation

scientific article published on 12 June 2008

Cytarabine dose of 36 g/m² compared with 12 g/m² within first consolidation in acute myeloid leukemia: results of patients enrolled onto the prospective randomized AML96 study

scientific article published on 23 May 2011

Deep learning detects acute myeloid leukemia and predicts NPM1 mutation status from bone marrow smears

scientific article published on 08 September 2021

Deep sequencing in CD34+ cells from peripheral blood enables sensitive detection of measurable residual disease in AML

scientific article published on 01 June 2022

Detection of relapse by sequential monitoring of chimerism in circulating CD34+ cells

scientific article published on 01 January 2002

Determination of mycophenolic acid and mycophenolate mofetil by high-performance liquid chromatography using postcolumn derivatization

scientific article

Development of early gastric cancer 4 and 5 years after complete remission of Helicobacter pylori associated gastric low grade marginal zone B cell lymphoma of MALT type.

scientific article

Diagnostic chimerism analysis after allogeneic stem cell transplantation: new methods and markers.

scientific article published on January 2004

Different types of NPM1 mutations in children and adults: evidence for an effect of patient age on the prevalence of the TCTG-tandem duplication in NPM1-exon 12

scientific article published on 07 December 2006

Distribution and levels of cell surface expression of CD33 and CD123 in acute myeloid leukemia

scientific article

Does time from diagnosis to treatment affect the prognosis of patients with newly diagnosed acute myeloid leukemia?

scientific article published on 04 June 2020

Donor cell leukemia: evidence for multiple preleukemic clones and parallel long term clonal evolution in donor and recipient

scientific article published on 28 March 2017

Donor-cell leukemia with novel genetic features 2 years after sex-mismatched T cell-depleted haploidentical stem cell transplantation

scientific article published on 22 February 2020

Dose-reduced conditioning and allogeneic hematopoietic stem cell transplantation from unrelated donors in 42 patients

scientific article published in August 2001

Dose-reduced conditioning for allogeneic blood stem cell transplantation: durable engraftment without antithymocyte globulin

scientific article published on 01 July 2000

Dynamics of epigenetic age following hematopoietic stem cell transplantation

scientific article published on 26 May 2017

EZH2 mutations and impact on clinical outcome - an analysis in 1604 patients with newly diagnosed acute myeloid leukemia

scientific article published on 14 August 2019

Early allogeneic blood stem cell transplantation after modified conditioning therapy during marrow aplasia: stable remission in high-risk acute myeloid leukemia

scientific article published in March 2001

Early intervention with allogeneic hematopoietic cell transplantation during chemotherapy-induced aplasia in patients with high-risk acute myeloid leukemia

scientific article published on 07 May 2013

Elevated AF1q expression is a poor prognostic marker for adult acute myeloid leukemia patients with normal cytogenetics

scientific article published in May 2009

Enzymatic assay for quantitative analysis of (D)-2-hydroxyglutarate

scientific article

Eradication of Helicobacter pylori and stability of remissions in low-grade gastric B-cell lymphomas of the mucosa-associated lymphoid tissue: results of an ongoing multicenter trial

scientific article published on 01 January 2000

Etiology and therapy of Helicobacter pylori-associated gastric lymphomas.

scientific article

Evaluation of STR informativity for chimerism testing--comparative analysis of 27 STR systems in 203 matched related donor recipient pairs

scientific article published in February 2004

Evaluation of TERT promoter mutations in urinary cell-free DNA and sediment DNA for detection of bladder cancer

scientific article published on 04 December 2018

Evidence for a graft-versus-tumor effect in refractory ovarian cancer

scientific article published on 28 January 2003

Evidence for a mutual regulation of p53 and c-myc expression in human colorectal cancer metastases

scientific article published on 01 December 1995

Evidence of a graft-versus-leukemia effect in chronic lymphocytic leukemia after reduced-intensity conditioning and allogeneic stem-cell transplantation: the Cooperative German Transplant Study Group.

scientific article

Evolution of NPM1-negative therapy-related myelodysplastic syndromes following curative treatment of NPM1-mutant AML

scientific article published on 10 July 2017

Evolution of a FLT3-TKD mutated subclone at meningeal relapse in acute promyelocytic leukemia

scientific article published on September 2016

Exome sequencing identifies frequent genomic loss of TET1 in IDH-wild-type glioblastoma

scientific article published on 31 October 2020

Expression and mutational analysis of Nm23-H1 in liver metastases of colorectal cancer

scientific article published on December 1994

Expression and regulation of NFAT (nuclear factors of activated T cells) in human CD34+ cells: down-regulation upon myeloid differentiation

scientific article

Expression profiling of gastric cancer samples by oligonucleotide microarray analysis reveals low degree of intra-tumor variability

scientific article published on October 2005

Extramedullary blast crisis of chronic myeloid leukemia after allogeneic hematopoietic stem cell transplantation mimicking aggressive, translocation t(14;18)-positive B-cell lymphoma

scientific article published on 29 November 2002

FLT3-ITD and tyrosine kinase domain mutants induce 2 distinct phenotypes in a murine bone marrow transplantation model

scientific article

Fast appearance of donor dendritic cells in human skin: dynamics of skin and blood dendritic cells after allogeneic hematopoietic cell transplantation

scientific article published on 01 March 2006

Favorable prognostic impact of NPM1 gene mutations in childhood acute myeloid leukemia, with emphasis on cytogenetically normal AML

scientific article published on 20 November 2008

Feasibility of azacitidine added to standard chemotherapy in older patients with acute myeloid leukemia--a randomised SAL pilot study

scientific article

Features of Ras activation by a mislocalized oncogenic tyrosine kinase: FLT3 ITD signals through K-Ras at the plasma membrane of acute myeloid leukemia cells

scientific article published on 13 August 2013

Focal inflammatory infiltrations in gastric biopsy specimens are suggestive of Crohn's disease. Crohn's Disease Study Group, Germany

scientific article published in August 1997

Frequency and prognostic impact of casein kinase 1A1 mutations in MDS patients with deletion of chromosome 5q.

scientific article published on 24 February 2015

Front-line imatinib treatment in children and adolescents with chronic myeloid leukemia: results from a phase III trial

scientific article published on 20 June 2018

GFI1 as a novel prognostic and therapeutic factor for AML/MDS.

scientific article published on 5 February 2016

Gemtuzumab ozogamicin as part of reduced-intensity conditioning for allogeneic hematopoietic cell transplantation in patients with relapsed acute myeloid leukemia

scientific article published in September 2008

Gene expression profiling in AML with normal karyotype can predict mutations for molecular markers and allows novel insights into perturbed biological pathways.

scientific article published on 29 April 2010

Gene-expression profiling of CD34+ hematopoietic cells expanded in a collagen I matrix

scientific article published on 15 September 2005

Genetic identification of patients with AML older than 60 years achieving long-term survival with intensive chemotherapy

scientific article published in 2021

Genetic variations of interleukin-23R (1143A>G) and BPI (A645G), but not of NOD2, are associated with acute graft-versus-host disease after allogeneic transplantation

scientific article published on 09 June 2010

Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene

scientific article published on 29 December 2011

Genomic BCR-ABL1 breakpoints in pediatric chronic myeloid leukemia.

scientific article

Genotype-outcome correlations in pediatric AML: the impact of a monosomal karyotype in trial AML-BFM 2004.

scientific article published on 25 April 2017

Graft clonogenicity and intensity of pre-treatment: factors affecting outcome of autologous peripheral hematopoietic cell transplantation in patients with acute myeloid leukemia in first remission

scientific article published on 01 December 2005

Graft-versus-host disease prophylaxis with everolimus and tacrolimus is associated with a high incidence of sinusoidal obstruction syndrome and microangiopathy: results of the EVTAC trial

scientific article published in January 2009

HLA-DRneg patients without acute promyelocytic leukemia show distinct immunophenotypic, genetic, molecular, and cytomorphologic characteristics compared to acute promyelocytic leukemia

scientific article published in September 2009

HPC enumeration with the Sysmex XE-2100 can guide further flow cytometric CD34(+) measurements and timing of leukaphereses

scientific article published in January 2003

Haploidentical bone marrow transplantation with post-grafting cyclophosphamide: multicenter experience with an alternative salvage strategy

scientific article published on 11 February 2011

Helicobacter and gastric MALT lymphoma

scientific article

Helicobacter heilmannii-associated primary gastric low-grade MALT lymphoma: complete remission after curing the infection

scientific article published on 01 May 2000

Hematopoietic cell transplantation in patients with intermediate and high-risk AML: results from the randomized Study Alliance Leukemia (SAL) AML 2003 trial

scientific article published in December 2014

Hematopoietic stem cell transplantation for complete IFN-γ receptor 1 deficiency: A multi-institutional survey

article by Joachim Roesler et al published December 2004 in The Journal of Pediatrics

High-dose cytarabine consolidation with or without additional amsacrine and mitoxantrone in acute myeloid leukemia: results of the prospective randomized AML2003 trial

scientific article published on 29 April 2013

Identification of acute myeloid leukaemia associated microRNA expression patterns

scientific article published on 01 January 2008

Imatinib mesylate selectively influences the cellular metabolism of cytarabine in BCR/ABL negative leukemia cell lines and normal CD34+ progenitor cells

scientific article published on January 2004

Immunohistochemical Surrogates for Genetic Alterations of CCDN1, PML, ALK, and NPM1 Genes in Lymphomas and Acute Myeloid Leukemia

scientific article published on October 29, 2010

Immunophenotyping is an independent factor for risk stratification in AML.

scientific article published in May 2003

Impact of CXCR4 inhibition on FLT3-ITD-positive human AML blasts

scientific article published on 24 December 2009

Impact of JAK2V617F mutation status, allele burden, and clearance after allogeneic stem cell transplantation for myelofibrosis

scientific article published on 20 May 2010

Impact of NPM1/FLT3-ITD genotypes defined by the 2017 European LeukemiaNet in patients with acute myeloid leukemia

scientific article published on 01 January 2020

Impact of PTPN11 mutations on clinical outcome analyzed in 1529 patients with acute myeloid leukemia

scientific article published on 01 September 2021

Impact of the type of the BCR-ABL fusion transcript on the molecular response in pediatric patients with chronic myeloid leukemia

scientific article published on 9 February 2010

Improved Outcomes With Retinoic Acid and Arsenic Trioxide Compared With Retinoic Acid and Chemotherapy in Non-High-Risk Acute Promyelocytic Leukemia: Final Results of the Randomized Italian-German APL0406 Trial

scientific article published on 31 October 2016

Improved outcome after stem-cell transplantation in FLT3/ITD-positive AML

scientific article published on 01 March 2007

In vivo expansion of co-transplanted T cells impacts on tumor re-initiating activity of human acute myeloid leukemia in NSG mice

scientific article published on 9 April 2013

Increased HDAC1 deposition at hematopoietic promoters in AML and its association with patient survival

scientific article published on 22 December 2010

Increased incidence of central nervous system hemorrhages in patients with secondary acute promyelocytic leukemia after treatment of multiple sclerosis with mitoxantrone?

scientific article published on June 2011

Individual outcome prediction for myelodysplastic syndrome (MDS) and secondary acute myeloid leukemia from MDS after allogeneic hematopoietic cell transplantation

scientific article published on 13 June 2017

Induction of short-term remission with single agent eltrombopag in refractory nucleophosmin-1-mutated acute myeloid leukemia

scientific article published on 5 September 2014

Infusion of bcr/abl peptide-reactive donor T cells to achieve molecular remission of chronic myeloid leukemia after CD34+ selected allogeneic hematopoietic cell transplantation

scientific article published on 31 August 2006

Inhibition of retinoic acid receptor signaling by Ski in acute myeloid leukemia

scientific article published in March 2006

Integration of mathematical model predictions into routine workflows to support clinical decision making in haematology

scientific article published on 10 February 2020

Intermediate-dose cytarabine plus mitoxantrone versus standard-dose cytarabine plus daunorubicine for acute myeloid leukemia in elderly patients

scientific article

Intratumoral heterogeneity and TERT promoter mutations in progressive/higher-grade meningiomas

scientific article

Is the polymerase chain reaction or cure of Helicobacter pylori infection of help in the differential diagnosis of early gastric mucosa-associated lymphatic tissue lymphoma?

scientific article published in March 1997

JAM-C Expression as a Biomarker to Predict Outcome of Patients with Acute Myeloid Leukemia-Letter

scientific article published on 17 October 2018

Kinetics of stem cell engraftment and clearance of leukaemia cells after allogeneic stem cell transplantation with reduced intensity conditioning in chronic myeloid leukaemia

scientific article published on 01 July 2002

Lack of interferon consensus sequence binding protein (ICSBP) transcripts in human myeloid leukemias

scientific article

Lack of point mutations in exons 11-23 of the retinoblastoma susceptibility gene RB-1 in liver metastases of colorectal carcinoma

scientific article published on 01 November 2000

Lenalidomide maintenance after allogeneic HSCT seems to trigger acute graft-versus-host disease in patients with high-risk myelodysplastic syndromes or acute myeloid leukemia and del(5q): results of the LENAMAINT trial

scientific article published on September 2012

Lipidomic approach for stratification of acute myeloid leukemia patients

scientific article

Long-Term Follow-Up and Impact of Comorbidity before Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Relapsed or Refractory Acute Myeloid Leukemia-Lessons Learned from the Prospective BRIDGE Trial

scientific article published on 17 May 2017

Long-term follow-up of gastric MALT lymphoma after H. pylori eradication.

scientific article

Long-term follow-up of gastric MALT lymphoma after Helicobacter pylori eradication.

scientific article

Long-term persistence of monoclonal B cells after cure of Helicobacter pylori infection and complete histologic remission in gastric mucosa-associated lymphoid tissue B-cell lymphoma

scientific article

Long-term prognosis of acute myeloid leukemia according to the new genetic risk classification of the European LeukemiaNet recommendations: evaluation of the proposed reporting system

scientific article published on 31 May 2011

Long-term results of all-trans retinoic acid and arsenic trioxide in non-high-risk acute promyelocytic leukemia: update of the APL0406 Italian-German randomized trial

scientific article published on 14 October 2019

Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia

scientific article published on 12 December 2016

Low frequency of calreticulin mutations in MDS patients

scientific article published on 21 May 2014

Lysyl oxidase expression is associated with inferior outcome and Extramedullary disease of acute myeloid leukemia

scientific article published on 12 June 2020

MDR1 and MRP1 gene expression are independent predictors for treatment outcome in adult acute myeloid leukaemia.

scientific article published on February 2005

MDR1 expression correlates with mutant p53 expression in colorectal cancer metastases

scientific article published on 01 January 1996

MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients

scientific article published on 01 September 2002

MLD according to the WHO classification in AML has no correlation with age and no independent prognostic relevance as analyzed in 1766 patients

scientific article published on 04 December 2007

MLL-PTD as a marker for minimal residual disease studies: quantification counts.

scientific article

MN1-Fli1 oncofusion transforms murine hematopoietic progenitor cells into acute megakaryoblastic leukemia cells.

scientific article

MPTH-12ISOCITRATE DEHYDROGENASE MUTANT DIFFUSE GLIOMAS GRADES II AND III ARE RADIOLOGICAL INDISTINGUISHABLE AND UNDERLIE ONLY MOLECULAR ALTERATIONS.

scientific article

MYST2 acetyltransferase expression and Histone H4 Lysine acetylation are suppressed in AML.

scientific article published on 10 June 2015

Marker chromosomes can arise from chromothripsis and predict adverse prognosis in acute myeloid leukemia

scientific article published on 24 January 2017

Matched unrelated or matched sibling donors result in comparable survival after allogeneic stem-cell transplantation in elderly patients with acute myeloid leukemia: a report from the cooperative German Transplant Study Group

scientific article published on 2 September 2008

Measurable residual disease-guided treatment with azacitidine to prevent haematological relapse in patients with myelodysplastic syndrome and acute myeloid leukaemia (RELAZA2): an open-label, multicentre, phase 2 trial

scientific article published on 12 November 2018

Mechanisms of resistance against PKC412 in resistant FLT3-ITD positive human acute myeloid leukemia cells

scientific article

Mesenchymal stem cells obtained after bone marrow transplantation or peripheral blood stem cell transplantation originate from host tissue

scientific article published on 13 August 2005

Midostaurin in patients with acute myeloid leukemia and FLT3-TKD mutations: a subanalysis from the RATIFY trial

scientific article published on 01 October 2020

Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation

scientific article published on 23 June 2017

Minimal residual disease-directed preemptive treatment with azacitidine in patients with NPM1-mutant acute myeloid leukemia and molecular relapse

scientific article published on 12 July 2011

Minimal/measurable residual disease in AML: consensus document from ELN MRD Working Party.

scientific article published on 12 January 2018

Mixed lymphohematopoietic chimerism and response in Wegener's granulomatosis

scientific article published on 01 June 2010

Mobilization of PML/RARalpha negative peripheral blood stem cells with a combination of G-CSF and CXCR4 blockade in relapsed acute promyelocytic leukemia pre-treated with arsenic trioxide

scientific article published on 8 October 2009

Molecular diagnostics in low-grade gastric marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type after Helicobacter pylori eradication therapy.

scientific article

Monitoring of acute myeloid leukemia patients after allogeneic stem cell transplantation employing semi-automated CD34+ donor cell chimerism analysis

scientific article published on 19 December 2013

Monitoring of donor chimerism in sorted CD34+ peripheral blood cells allows the sensitive detection of imminent relapse after allogeneic stem cell transplantation

scientific article published on November 2009

Mutant DNMT3A: teaming up to transform

scientific article published on June 14, 2012

Mutations in ras proto-oncogenes are associated with lower mdr1 gene expression in adult acute myeloid leukaemia

scientific article

Mycophenolate mofetil and cyclosporine as graft-versus-host disease prophylaxis after allogeneic blood stem cell transplantation.

scientific article published in February 1999

Myelodysplastic syndromes with a deletion 5q display a characteristic immunophenotypic profile suitable for diagnostics and response monitoring

scientific article published on 25 November 2014

Ongoing somatic mutations and clonal expansions after cure of Helicobacter pylori infection in gastric mucosa-associated lymphoid tissue B-cell lymphoma

scientific article published on December 1998

P53 and induction of apoptosis as a target for anticancer therapy.

scientific article published on July 1996

Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: a Cancer and Leukemia Group B study

scientific article

Pilot Study on Mass Spectrometry-Based Analysis of the Proteome of CD34⁺CD123⁺ Progenitor Cells for the Identification of Potential Targets for Immunotherapy in Acute Myeloid Leukemia.

scientific article published on 12 February 2018

Pim2 cooperates with PML-RARalpha to induce acute myeloid leukemia in a bone marrow transplantation model

scientific article published on 9 March 2010

Prediction of hematopoietic stem cell yield after mobilization with granulocyte-colony-stimulating factor in healthy unrelated donors

scientific article

Prediction of post-remission survival in acute myeloid leukaemia: a post-hoc analysis of the AML96 trial

scientific article

Pretransplant NPM1 MRD levels predict outcome after allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia

scientific article published on 29 July 2016

Pretreatment d-2-hydroxyglutarate serum levels negatively impact on outcome in IDH1-mutated acute myeloid leukemia.

scientific article published on 19 November 2015

Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML).

scientific article

Prevalence and prognostic value of IDH1 and IDH2 mutations in childhood AML: a study of the AML-BFM and DCOG study groups

scientific article published on 07 June 2011

Problems with interphase fluorescence in situ hybridization in detecting BCR/ABL-positive cells in some patients using a novel technique with extra signals

scientific article

Profiling of aberrant DNA methylation in acute myeloid leukemia reveals subclasses of CG-rich regions with epigenetic or genetic association

scientific article published on 20 June 2018

Profiling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia

scientific article

Prognostic effect of calreticulin mutations in patients with myelofibrosis after allogeneic hematopoietic stem cell transplantation

scientific article published on 07 February 2014

Prognostic significance of N-RAS and K-RAS mutations in 232 patients with acute myeloid leukemia

scientific article published on 01 November 2004

Prophylactic transfer of BCR-ABL-, PR1-, and WT1-reactive donor T cells after T cell-depleted allogeneic hematopoietic cell transplantation in patients with chronic myeloid leukemia

scientific article published on 03 May 2011

Quality assurance in RT-PCR-based BCR/ABL diagnostics--results of an interlaboratory test and a standardization approach

scientific article published in October 2000

Quantification of Bcr-Abl transcripts in chronic myelogenous leukemia (CML) using standardized, internally controlled, competitive differential PCR (CD-PCR)

scientific article published on October 1996

Quantitative comparison of microarray experiments with published leukemia related gene expression signatures

scientific article

Quantitative proteomics reveals specific metabolic features of Acute Myeloid Leukemia stem cells

scientific article published on 18 June 2020

RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation.

scientific article

Radiographic assessment of contrast enhancement and T2/FLAIR mismatch sign in lower grade gliomas: correlation with molecular groups

scientific article published on 07 December 2018

Rapid and sensitive typing of NPM1 mutations using LNA-mediated PCR clamping

scientific article published on 07 September 2006

Rapid flow cytometric detection of aberrant cytoplasmic localization of nucleophosmin (NPMc) indicating mutant NPM1 gene in acute myeloid leukemia.

scientific article published on 19 August 2010

Rapid quantification of mixed chimerism using multiplex amplification of short tandem repeat markers and fluorescence detection

scientific article published on 01 May 1999

Rapid reconstitution of dendritic cells after allogeneic transplantation of CD133+ selected hematopoietic stem cells

scientific article published on 01 January 2005

Reconstitution of 6-sulfo LacNAc dendritic cells after allogeneic stem-cell transplantation

scientific article published on 01 June 2012

Reduced intensity conditioning allows for up-front allogeneic hematopoietic stem cell transplantation after cytoreductive induction therapy in newly-diagnosed high-risk acute myeloid leukemia

scientific article published on 01 April 2006

Reduced non-relapse mortality after reduced intensity conditioning in advanced chronic lymphocytic leukemia

scientific article

Reduced-intensity conditioning with busulfan and fludarabine with or without antithymocyte globulin in HLA-identical sibling transplantation--a retrospective analysis

scientific article

Regression of gastric MALT lymphoma after eradication of Helicobacter pylori is predicted by endosonographic staging. MALT Lymphoma Study Group

scientific article published on 01 October 1997

Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. MALT Lymphoma Study Group

scientific article

Reply to: 'Flow cytometric identification of acute myeloid leukemia with limited differentiation and NPM1 type A mutation: a new biologically defined entity' by Kern et al

scientific article published on 18 February 2011

Response dynamics of pediatric patients with chronic myeloid leukemia on imatinib therapy

scientific article published on 17 November 2016

Retinoic acid and arsenic trioxide for acute promyelocytic leukemia

scientific article

Rhinocerebral zygomycosis and subsequent treatment decisions in a young patient with AML.

scientific article published in July 2009

Risk stratification using a new prognostic score for patients with secondary acute myeloid leukemia: results of the prospective AML96 trial.

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Role of Donor Clonal Hematopoiesis in Allogeneic Hematopoietic Stem-Cell Transplantation

scientific article published on 07 November 2018

SETBP1 mutation analysis in 944 patients with MDS and AML.

scientific article published on 7 May 2013

SNP analyses in cytarabine metabolizing enzymes in AML patients and their impact on treatment response and patient survival: identification of CDA SNP C-451T as an independent prognostic parameter for survival.

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Second cancers and residual disease in patients treated for gastric mucosa-associated lymphoid tissue lymphoma by Helicobacter pylori eradication and followed for 10 years

scientific article published on 27 June 2012

Sensitivity toward tyrosine kinase inhibitors varies between different activating mutations of the FLT3 receptor.

scientific article published on 27 March 2003

Sequential H. pylori eradication and radiation therapy with reduced dose compared to standard dose for gastric MALT lymphoma stages IE & II1E: a prospective randomized trial

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Sequential monitoring of chimerism and detection of minimal residual disease after allogeneic blood stem cell transplantation (BSCT) using multiplex PCR amplification of short tandem repeat-markers

scientific article published on 01 February 2001

Sex and body mass index but not CXCL12 801 G/A polymorphism determine the efficacy of hematopoietic cell mobilization: a study in healthy volunteer donors

scientific article published on 23 July 2013

Simple and rapid detection of factor V Leiden by allele-specific PCR amplification

scientific article published on 01 May 1996

Simple and sensitive detection of mutations in the ras proto-oncogenes using PNA-mediated PCR clamping

scientific article published on March 1996

Single agent talacotuzumab demonstrates limited efficacy but considerable toxicity in elderly high-risk MDS or AML patients failing hypomethylating agents

scientific article published on 03 December 2019

Somatic TP53 mutations characterize preleukemic stem cells in acute myeloid leukemia.

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Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With FLT3-Internal Tandem Duplication Mutation (SORMAIN)

scientific article published on 16 July 2020

Sorafenib in combination with intensive chemotherapy in elderly patients with acute myeloid leukemia: results from a randomized, placebo-controlled trial

scientific article published on 29 July 2013

Specificity of immunophenotyping in acute promyelocytic leukemia

scientific article published on 01 December 2000

Stable engraftment after megadose blood stem cell transplantation across the HLA barrier: the case for natural killer cells as graft-facilitating cells

scientific article published on 01 July 1999

Stable molecular remission induced by imatinib mesylate (STI571) in a patient with CML lymphoid blast crisis relapsing after allogeneic stem cell transplantation

scientific article published in April 2003

Strategies and clinical implications of chimerism diagnostics after allogeneic hematopoietic stem cell transplantation

scientific article published on January 2004

Strong BCL10 nuclear expression identifies gastric MALT lymphomas that do not respond to H pylori eradication

scientific article published on January 2006

Successful combination of anti-CD33 antibody (gemtuzumab ozogamicin) and minimal conditioning before second allografting in recurrent acute myeloid leukaemia

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Successful preemptive cidofovir treatment for CMV antigenemia after dose-reduced conditioning and allogeneic blood stem cell transplantation

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Successful treatment of molecular relapse in NPM1-positive AML using 5-azacytidine

scientific article published on 24 September 2009

Sustained complete molecular remission after imatinib discontinuation in children with chronic myeloid leukemia.

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T(11;18) is a marker for all stage gastric MALT lymphomas that will not respond to H. pylori eradication

scientific article published on 01 May 2002

TERT Promoter Mutation Detection in Cell-Free Tumor-Derived DNA in Patients with IDH Wild-Type Glioblastomas: A Pilot Prospective Study

scientific article published on 25 June 2018

TP53 mutation in patients with high-risk acute myeloid leukaemia treated with allogeneic haematopoietic stem cell transplantation

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Targeted isolation of cloned genomic regions by recombineering for haplotype phasing and isogenic targeting.

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Targeted sequencing of SMO and AKT1 in anterior skull base meningiomas

scientific article published on 25 November 2016

Telomere length and hTERT expression in patients with acute myeloid leukemia correlates with chromosomal abnormalities

scientific article published on 01 March 2005

Terminal myeloid differentiation in vivo is induced by FLT3 inhibition in FLT3/ITD AML.

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The clinical mutatome of core binding factor leukemia

scientific article published on 02 January 2020

The level of residual disease based on mutant NPM1 is an independent prognostic factor for relapse and survival in AML.

scientific article published on 8 May 2013

The prognostic impact of 17p (p53) deletion in 2272 adults with acute myeloid leukemia

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The prognostic potential of monitoring disease dynamics in NPM1-positive acute myeloid leukemia

scientific article published on 23 January 2019

The response to lenalidomide of myelodysplastic syndrome patients with deletion del(5q) can be sequentially monitored in CD34+ progenitor cells

scientific article published on 30 January 2009

The status of p53 in the metastatic progression of colorectal cancer

scientific article published on 01 July 1997

Therapy of gastric mucosa associated lymphoid tissue lymphoma

scientific article published on July 2007

Third-party mesenchymal stem cells as part of the management of graft-failure after haploidentical stem cell transplantation

scientific article published on 24 June 2009

Translocation t(11;18) absent in early gastric marginal zone B-cell lymphoma of MALT type responding to eradication of Helicobacter pylori infection

scientific article published on 01 June 2000

Treatment of relapsing leukemia after allogeneic blood stem cell transplantation by using dose-reduced conditioning followed by donor blood stem cells and GM-CSF

scientific article published on 01 March 2001

Two cycles of risk-adapted consolidation therapy in patients with acute promyelocytic leukemia. Results from the SAL-AIDA2000 trial

scientific article published on 05 November 2014

Tyrosine kinase mutations of JAK2 are rare events in AML but influence prognosis of patients with CBF-leukemias

scientific article published on 01 January 2007

Underestimation of inversion (16) in acute myeloid leukaemia using standard cytogenetics as compared with polymerase chain reaction: results of a prospective investigation

scientific article published on 01 September 1997

Use of Minimal Residual Disease in Acute Myeloid Leukemia Therapy

scientific article published on 30 January 2020

Validation of the Revised Pretransplant Assessment of Mortality Score in Patients with Acute Myelogenous Leukemia Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

scientific article published on 21 May 2018

WHO classification of myeloid neoplasms and leukemia

scientific article published on January 2010

What role does Helicobacter pylori eradication play in gastric MALT and gastric MALT lymphoma?

scientific article published on December 1997

ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.

scientific article published on 2 June 2016

bcl-2 expression is reciprocal to p53 and c-myc expression in metastatic human colorectal cancer

scientific article published on 01 July 1998

miR-10a overexpression is associated with NPM1 mutations and MDM4 downregulation in intermediate-risk acute myeloid leukemia

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miR-451a abrogates treatment resistance in FLT3-ITD-positive acute myeloid leukemia.

scientific article published on 21 March 2018