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List of works by Manuel Varas

A short hairpin RNA-based adjuvant targeting NF-κB repressor IκBα promotes migration of dermal dendritic cells to draining lymph nodes and antitumor CTL responses induced by DNA vaccination.

scientific article

An integrated mechanism of cardiomyocyte nuclear Ca(2+) signaling

scientific article published on 02 July 2014

Angiogenic Properties of Menstrual Stem Cells Are Impaired in Women with a History of Preeclampsia

scientific article published on 27 January 2019

Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro.

scientific article published in May 2010

Astrocyte-Derived Small Extracellular Vesicles Regulate Dendritic Complexity through miR-26a-5p Activity

scientific article published on 10 April 2020

BCG-induced cytokine release in bladder cancer cells is regulated by Ca signaling

scientific article published on 13 December 2018

CK2 inhibition with silmitasertib promotes methuosis-like cell death associated to catastrophic massive vacuolization of colorectal cancer cells

article published in 2019

Caveolin-1-containing extracellular vesicles transport adhesion proteins and promote malignancy in breast cancer cell lines

scientific article published on 19 October 2018

Chemo‐small extracellular vesicles released in cisplatin‐resistance ovarian cancer cells are regulated by the lysosomal function

scientific article published in 2024

Colon cancer cell invasion is promoted by protein kinase CK2 through increase of endothelin-converting enzyme-1c protein stability.

scientific article published on 16 October 2015

Connexin-46 Contained in Extracellular Vesicles Enhance Malignancy Features in Breast Cancer Cells

scientific article published on 28 April 2020

Convergent Met and voltage-gated Ca2+ channel signaling drives hypermigration of Toxoplasma-infected dendritic cells

scientific article published on 11 March 2020

Correction: TIMP-1 promotes hypermigration of Toxoplasma-infected primary dendritic cells via CD63-ITGB1-FAK signaling (doi:10.1242/jcs.225193)

scientific article published on 25 February 2019

Effects of earthquake on perinatal outcomes: A Chilean register-based study.

scientific article published on 23 February 2018

Enalapril attenuates downregulation of Angiotensin-converting enzyme 2 in the late phase of ventricular dysfunction in myocardial infarcted rat

scientific article published on 14 August 2006

Endothelial Nitric Oxide Synthase Is Present in Dendritic Spines of Neurons in Primary Cultures

scientific article

Expression of mitochondrial non-coding RNAs (ncRNAs) is modulated by high risk human papillomavirus (HPV) oncogenes.

scientific article published on 26 April 2012

Frizzled-1 receptor regulates adult hippocampal neurogenesis.

scientific article published on 15 March 2016

GIT1 protects against breast cancer growth through negative regulation of Notch

scientific article published on 22 March 2022

HPV-18 E2 protein downregulates antisense noncoding mitochondrial RNA-2, delaying replicative senescence of human keratinocytes

scientific article published on 01 December 2018

In vivo knockdown of antisense non-coding mitochondrial RNAs by a lentiviral-encoded shRNA inhibits melanoma tumor growth and lung colonization

scientific article published on 14 July 2017

Increased Circulating Levels of Tissue-Type Plasminogen Activator Are Associated with the Risk of Spontaneous Abortion During the First Trimester of Pregnancy

scientific article published on 01 April 2020

Maternal plasma concentrations of the placental specific sFLT-1 variant, sFLT-1 e15a, in fetal growth restriction and preeclampsia.

scientific article

Migratory activation of parasitized dendritic cells by the protozoan Toxoplasma gondii 14-3-3 protein

scientific article

Oral extracellular vesicles in early pregnancy can identify patients at risk of developing gestational diabetes mellitus

scientific article published on 26 June 2019

PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination

scientific article published on 01 April 2019

Periodontitis and placental growth factor in oral fluids are early pregnancy predictors of gestational diabetes mellitus.

scientific article

Physicochemical characterization of chitosan-hyaluronan-coated solid lipid nanoparticles for the targeted delivery of paclitaxel: a proof-of-concept study in breast cancer cells

scientific article published on 9 February 2017

Placental Aromatase Is Deficient in Placental Ischemia and Preeclampsia

scientific article

Placental biomarkers and angiogenic factors in oral fluids of patients with preeclampsia

scientific article

Prostate tumor-induced angiogenesis is blocked by exosomes derived from menstrual stem cells through the inhibition of reactive oxygen species.

scientific article published on 06 June 2016

Reduced FOXM1 Expression Limits Trophoblast Migration and Angiogenesis and Is Associated With Preeclampsia

scientific article published on 30 May 2018

Small Extracellular Vesicles Released from Ovarian Cancer Spheroids in Response to Cisplatin Promote the Pro-Tumorigenic Activity of Mesenchymal Stem Cells

scientific article published on 09 October 2019

Small Extracellular Vesicles in Rat Serum Contain Astrocyte-Derived Protein Biomarkers of Repetitive Stress.

scientific article published in March 2019

Sublethal caspase activation promotes generation of cardiomyocytes from embryonic stem cells

scientific article published on 12 March 2015

TIMP-1 promotes hypermigration of Toxoplasma-infected primary dendritic cells via CD63-ITGB1-FAK signaling

scientific article published on 04 February 2019

Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through reduction in survival and invasion factors

scientific article published on 6 August 2016

The Crosstalk between Ovarian Cancer Stem Cell Niche and the Tumor Microenvironment

scientific article published on 27 July 2017

The ROR2 tyrosine kinase receptor regulates dendritic spine morphogenesis in hippocampal neurons

scientific article

The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state

scientific article published on 13 May 2016

The glycolytic enzyme aldolase C is up-regulated in rat forebrain microsomes and in the cerebrospinal fluid after repetitive fluoxetine treatment.

scientific article

Toxoplasma gondii infection shifts dendritic cells into an amoeboid rapid migration mode encompassing podosome dissolution, secretion of TIMP-1, and reduced proteolysis of extracellular matrix.

scientific article

Two Chronic Stress Models Based on Movement Restriction in Rats Respond Selectively to Antidepressant Drugs: Aldolase C As a Potential Biomarker

scientific article

Vaccination-induced skin-resident memory CD8+ T cells mediate strong protection against cutaneous melanoma.

scientific article published on 19 March 2018

Voltage-dependent calcium channel signaling mediates GABAA receptor-induced migratory activation of dendritic cells infected by Toxoplasma gondii.

scientific article published on 7 December 2017

Wnt5a inhibits K(+) currents in hippocampal synapses through nitric oxide production.

scientific article published on 23 August 2015

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