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List of works by Caroline Tiemessen

A Common NLRC4 Gene Variant Associates With Inflammation and Pulmonary Function in Human Immunodeficiency Virus and Tuberculosis

scientific article published on 22 November 2019

A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation

scientific article published in Nature Communications

A novel FCGR3A intragenic haplotype is associated with increased FcγRIIIa/CD16a cell surface density and population differences.

scientific article

Adenovirus 41 growth in semi-permissive cells shows multiple-hit kinetics

scientific article published in January 1990

Adenovirus 41 replication: cell-related differences in viral gene transcription

scientific article

Adenovirus type 40 and 41 growth in vitro: host range diversity reflected by differences in patterns of DNA replication

scientific article published on February 1994

Africa: the next frontier for human disease gene discovery?

scientific article published on 09 September 2011

African infants' CCL3 gene copies influence perinatal HIV transmission in the absence of maternal nevirapine

scientific article published on August 2007

Age at antiretroviral therapy initiation and cell-associated HIV-1 DNA levels in HIV-1-infected children

scientific article published on 12 April 2018

Age-related changes in expression of CXCR4 and CCR5 on peripheral blood leukocytes from uninfected infants born to human immunodeficiency virus type 1-infected mothers

scientific article published on January 2004

Age-related changes in polymorphonuclear neutrophil characteristics in infants born to human immunodeficiency virus type 1 seropositive mothers

scientific article published in April 2004

Alginate microbead-encapsulated silver complexes for selective delivery of broad-spectrum silver-based microbicides

scientific article published on 29 June 2015

Altered expression of CD88 and associated impairment of complement 5a-induced neutrophil responses in human immunodeficiency virus type 1-infected patients with and without pulmonary tuberculosis

scientific article published on 11 January 2001

Altered expression of Fc gammaRIII (CD16) on polymorphonuclear neutrophils from individuals with human immunodeficiency virus type 1 disease and pulmonary tuberculosis ⬇️

scientific article published on November 1, 1997

Altered expression of L-selectin (CD62L) on polymorphonuclear neutrophils of children vertically infected with human immunodeficiency virus type 1.

scientific article published in July 2001

Amino acid variation within the fusion protein of respiratory syncytial virus subtype A and B strains during annual epidemics in South Africa

scientific article published in March 2005

Anti-nucleocapsid protein immune responses counteract pathogenic effects of Rift Valley fever virus infection in mice

scientific article

Antituberculosis treatment: increasing evidence for drug effects on innate cellular immunity

scientific article

CC chemokines and protective immunity: insights gained from mother-to-child transmission of HIV.

scientific article published on March 2007

CCR5 delta32 heterozygosity is associated with an increase in CXCR4 cell surface expression

scientific article published on 01 June 2003

CCR5 expression, haplotype and immune activation in protection from infection in HIV-exposed uninfected individuals in HIV-serodiscordant relationships

scientific article published on 11 April 2017

CCR5 promoter haplotypes differentially influence CCR5 expression on natural killer and T cell subsets in ethnically divergent HIV-1 uninfected South African populations

scientific article published on 15 August 2012

CD38 expression on CD8(+) T cells as a prognostic marker in vertically HIV-infected pediatric patients

scientific article published in June 2002

CXCR6 gene characterization in two ethnically distinct South African populations and association with viraemic disease control in HIV-1-infected black South African individuals

scientific article published on 17 April 2017

Cellular Expression and Crystal Structure of the Murine Cytomegalovirus Major Histocompatibility Complex Class I-like Glycoprotein, m153

scientific article

Characterisation of near-full length genome sequences of three South African human immunodeficiency virus type 1 subtype C isolates

scientific article published on January 2003

Characterization of a single SA7-like VA RNA gene in subgroup F adenoviruses

scientific article published on August 1993

Characterization of human blood dendritic cells: cytokine profiles

scientific article published on 01 January 1995

Characterization of rotaviruses and subgroup F adenoviruses from acute summer gastroenteritis in South Africa

scientific article published in February 1986

Chronic HIV-1 Infection Alters the Cellular Distribution of FcγRIIIa and the Functional Consequence of the FcγRIIIa-F158V Variant

article

Circulating levels of stromal cell-derived factor 1alpha and interleukin 7 in HIV type 1 infection and pulmonary tuberculosis are reciprocally related to CXCR4 expression on peripheral blood leukocytes

scientific article published on 01 June 2003

Cis-regulatory genetic variants in the CCR5 gene and natural HIV-1 control in black South Africans

scientific article published on 15 May 2019

Common Variation in NLRP3 Is Associated With Early Death and Elevated Inflammasome Biomarkers Among Advanced HIV/TB Co-infected Patients in Botswana.

scientific article

Comparison of a quantitative Real-Time PCR assay and droplet digital PCR for copy number analysis of the CCL4L genes

scientific article published on 12 April 2014

Contribution of variable CCL3L copy number to CCL3 protein production in two ethnically divergent South African populations

scientific article published on 05 January 2013

Cryptococcal-related Mortality Despite Fluconazole Preemptive Treatment in a Cryptococcal Antigen Screen-and-Treat Program

scientific article published on 01 April 2020

Cutting Edge: Unusual NK cell responses to HIV-1 peptides are associated with protection against maternal-infant transmission of HIV-1.

scientific article

Cytokine-induced interleukin-8 production is depressed in chronic as opposed to acute human immunodeficiency virus 1 infection of promonocytic cells

scientific article published on June 2000

Defective neutrophil degranulation induced by interleukin-8 and complement 5a and down-regulation of associated receptors in children vertically infected with human immunodeficiency virus type 1

scientific article

Depressed Phagocytosis and Oxidative Burst in Polymorphonuclear Leukocytes from Individuals with Pulmonary Tuberculosis with or without Human Immunodeficiency Virus Type 1 Infection ⬇️

scientific article published on January 1, 1998

Detection and molecular characterization of urinary tract HIV-1 populations

scientific article published on 24 September 2019

Detection and typing of subgroup F adenoviruses using the polymerase chain reaction

scientific article published on May 1996

Detection of human immunodeficiency virus type 1 envelope peptide- stimulated T-helper cell responses and variations in the corresponding regions of viral isolates among vertically infected children

scientific article published on April 2004

Development of a whole blood intracellular cytokine staining assay for mapping CD4(+) and CD8(+) T-cell responses across the HIV-1 genome.

scientific article published on 31 May 2007

Differences are evident within the CXCR4-CXCL12 axis between ethnically divergent South African populations.

scientific article

Distribution of the human immunodeficiency virus coreceptors CXCR4 and CCR5 on leukocytes of persons with human immunodeficiency virus type 1 infection and pulmonary tuberculosis: implications for pathogenesis

scientific article published in November 2001

Duration of sample storage dramatically alters expression of the human immunodeficiency virus coreceptors CXCR4 and CCR5

scientific article

Dysregulated production of interleukin-8 in individuals infected with human immunodeficiency virus type 1 and Mycobacterium tuberculosis.

scientific article

Early antiretroviral treatment of infants to attain HIV remission

scientific article published on 07 January 2020

Effect of Maternal HIV-1 Status and Antiretroviral Drugs on Haematological Profiles of South African Infants in Early Life ⬇️

scientific article published on August 12, 2010

Effects of Anticoagulants and Temperature on Expression of Activation Markers CD11b and HLA-DR on Human Leukocytes ⬇️

scientific article published on September 1, 1998

Evolution and diversity of HIV-1 in Africa--a review.

scientific article

FOXP3 expression is upregulated in CD4T cells in progressive HIV-1 infection and is a marker of disease severity

scientific article

Fiber sequence heterogeneity in subgroup F adenoviruses

scientific article published on November 1990

Frequencies of immune hypersensitivity reaction-associated HLA class I alleles in healthy South African Indian and mixed ancestry populations determined by a novel real-time PCR assay.

scientific article published on 25 August 2014

G6PD variant distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19

scientific article published on 02 June 2020

Gamma interferon production in response to Mycobacterium bovis BCG and Mycobacterium tuberculosis antigens in infants born to human immunodeficiency virus-infected mothers

scientific article

Genetic diversity and molecular epidemiology of respiratory syncytial virus over four consecutive seasons in South Africa: identification of new subgroup A and B genotypes

scientific article published in September 2001

Genetic variability in markers of HLA-C expression in two diverse South African populations

scientific article

Genetic variants of NRAMP1 and active tuberculosis in Japanese populations. International Tuberculosis Genetics Team.

scientific article published in July 2000

Genetic variation within the gene encoding the HIV-1 CCR5 coreceptor in two South African populations

scientific article

Genome-Wide Association Study Identifies Novel Colony Stimulating Factor 1 Locus Conferring Susceptibility to Cryptococcosis in Human Immunodeficiency Virus-Infected South Africans

scientific article published on 16 October 2020

HIV and Solid Organ Transplantation: Where Are we Now

scientific article published on 01 October 2019

HIV diagnostic challenges in breast-fed infants of mothers on antiretroviral therapy

scientific article published on 01 September 2019

HIV-1 Subtype A, D, G, AG and unclassified sequences identified in South Africa

scientific article published on 01 June 2002

Helper function of adenovirus 2 for adenovirus 41 antigen synthesis in semi-permissive and non-permissive cells

scientific article published in January 1988

Host CCL3L1 gene copy number in relation to HIV-1-specific CD4+ and CD8+ T-cell responses and viral load in South African women

scientific article published on July 2008

Human immunodeficiency virus (HIV)-specific cellular immune responses in newborns exposed to HIV in utero

scientific article

Human immunodeficiency virus type 1 envelope-stimulated interleukin-2 production and survival of infected children with severe and mild clinical disease

scientific article published on 24 August 2001

Human leukocyte antigen associations with protection against tuberculosis infection and disease in human immunodeficiency virus-1 infected individuals, despite household tuberculosis exposure and immune suppression

scientific article published on 19 November 2020

Human leukocyte antigen class I (A, B and C) allele and haplotype variation in a South African Indian population

scientific article published on 29 April 2017

Human leukocyte antigen class I (A, B and C) allele and haplotype variation in a South African Mixed ancestry population

scientific article

Human leukocyte antigen class I (A, B, C) and II (DRB1) diversity in the black and Caucasian South African population

scientific article published on 23 October 2011

Human leukocyte antigen class I (A, B, C) and class II (DPB1, DQB1, DRB1) allele and haplotype variation in Black South African individuals

scientific article published on 13 December 2019

Identification and sequence analysis of two novel cryptic plasmids isolated from the vaginal mucosa of South African women

scientific article published on 01 June 2018

Identification of HIV type 1 intersubtype recombinants in South Africa using env and gag heteroduplex mobility assays

scientific article

Identification of a novel allele, HLA-DPB1*34:01:01:03, in Black South African individuals

scientific article published on 08 September 2019

Identification of a novel recombinant allele, HLA-DPB1*835:01:01:02, in Black South African individuals

scientific article published on 03 September 2019

Identification of human immunodeficiency virus-1 specific CD8+ and CD4+ T cell responses in perinatally-infected infants and their mothers

scientific article published on April 2009

Identification of new variants within the two functional genes CCL3 and CCL3L encoding the CCL3 (MIP-1alpha) chemokine: implications for HIV-1 infection

scientific article published on 25 November 2008

Identification of predominant culturable vaginal Lactobacillus species and associated bacteriophages from women with and without vaginal discharge syndrome in South Africa

scientific article published on 28 October 2010

Immune pathogenesis of pediatric HIV-1 infection

scientific article

Immune-based prevention of mother-to-child HIV-1 transmission.

scientific article published on April 2007

Impaired interleukin-8-induced degranulation of polymorphonuclear neutrophils from human immunodeficiency virus type 1-infected individuals

scientific article

In vivo effects of HIV-1 exposure in the presence and absence of single-dose nevirapine on cellular plasma activation markers of infants born to HIV-1-seropositive mothers

scientific article published on August 2006

Infection by enteric adenoviruses, rotaviruses, and other agents in a rural African environment

scientific article published on July 1989

Influence of intragenic CCL3 haplotypes and CCL3L copy number in HIV-1 infection in a sub-Saharan African population

scientific article published on 15 November 2012

Interleukin-4 regulation of cytokine-induced HIV1 and interleukin-8 expression in promonocytic U1 cells is concentration- and cytokine-dependent

scientific article published on 01 January 1998

Interleukin-8 concentrations in the peripheral circulation of human immunodeficiency virus type 1-infected children suggest blunted chemokine responses

scientific article published in August 2001

Interleukin-8 fails to induce human immunodeficiency virus-1 expression in chronically infected promonocytic U1 cells but differentially modulates induction by proinflammatory cytokines

scientific article

KIR-HLA and maternal-infant HIV-1 transmission in sub-Saharan Africa

scientific article

KIR2DS4 allelic variants: Differential effects on in utero and intrapartum HIV-1 mother-to-child transmission

scientific article published on 25 September 2013

Killer-cell immunoglobulin-like receptor (KIR) and human leukocyte antigen (HLA) class I genetic diversity in four South African populations

scientific article published on 29 May 2017

Killer-cell immunoglobulin-like receptor genotyping and HLA killer-cell immunoglobulin-like receptor-ligand identification by real-time polymerase chain reaction

scientific article

Living donor liver transplant from an HIV-positive mother to her HIV-negative child: opening up new therapeutic options

scientific article

Low Pretreatment Viral Loads in Infants With HIV in an Era of High-maternal Antiretroviral Therapy Coverage

scientific article published on 07 September 2020

Low maternal viral loads and reduced granulocyte-macrophage colony-stimulating factor levels characterize exposed, uninfected infants who develop protective human immunodeficiency virus type 1-specific responses

scientific article published on 14 February 2007

Marked differences in CCR5 expression and activation levels in two South African populations

scientific article

Maternal human leukocyte antigen-G (HLA-G) genetic variants associate with in utero mother-to-child transmission of HIV-1 in Black South Africans

scientific article

Measles virus genotype B2 is not inactive: evidence of continued circulation in Africa

scientific article

Mechanisms of HIV persistence in HIV reservoirs.

scientific article published on 27 January 2017

Natural killer cell responses to HIV-1 peptides are associated with more activating KIR genes and HLA-C genes of the C1 allotype

scientific article published on July 2011

Natural killer cells that respond to human immunodeficiency virus type 1 (HIV‐1) peptides are associated with control of HIV‐1 infection

scientific article

Needs must: living donor liver transplantation from an HIV-positive mother to her HIV-negative child in Johannesburg, South Africa

scientific article published on 01 May 2019

Occurrence of additional NF-kappaB-binding motifs in the long terminal repeat region of South African HIV type 1 subtype C isolates

scientific article published in February 2000

P08-02. Genetic variation within the gene encoding the HIV-1 CCR5 coreceptor in two South African population groups

scientific article published on 22 October 2009

P08-04. The role of class I HLA-B and HLA-Cw in disease progression and maternal-infant HIV-1 transmission in a South African population

article

Partner HIV Serostatus Impacts Viral Load, Genital HIV Shedding, and Immune Activation in HIV-Infected Individuals

scientific article published on 01 September 2019

Perinatal HIV-1 transmission: Fc gamma receptor variability associates with maternal infectiousness and infant susceptibility

scientific article published on 10 June 2016

Plasmid transduction using bacteriophage Phi(adh) for expression of CC chemokines by Lactobacillus gasseri ADH.

scientific article

Pre-treatment minority HIV-1 drug resistance mutations and long term virological outcomes: is prediction possible?

scientific article published on 12 October 2016

Prevalence and outcomes of HIV-1 diagnostic challenges during universal birth testing - an urban South African observational cohort

scientific article published on August 2017

Prevalence of premalignant cervical lesions in women with a long-term nonprogressor or HIV controller phenotype

scientific article published on January 2014

Quantifying the dynamics of HIV decline in perinatally-infected neonates on antiretroviral therapy

scientific article published on 22 June 2020

RICH2 is implicated in viraemic control of HIV-1 in black South African individuals

scientific article published on 6 January 2017

Recommendations for analytical antiretroviral treatment interruptions in HIV research trials-report of a consensus meeting

scientific article published on 15 March 2019

Reduced HIV-stimulated T-helper cell reactivity in cord blood with short-course antiretroviral treatment for prevention of maternal-infant transmission

scientific article

Reduced ability of newborns to produce CCL3 is associated with increased susceptibility to perinatal human immunodeficiency virus 1 transmission

scientific article published on July 2006

Reduced expression of interleukin-8 receptors A and B on polymorphonuclear neutrophils from persons with human immunodeficiency virus type 1 disease and pulmonary tuberculosis

scientific article published in April 1998

Reply to: "Experimental aspects of copy number variant assays at CCL3L1".

scientific article published in October 2009

Respiratory syncytial virus nucleoprotein-specific cytotoxic T-cell epitopes in a South African population of diverse HLA types are conserved in circulating field strains

scientific article

Response to Zhao and Zhou: Diagnosis of HIV infection in breastfed infants of mothers on antiretroviral therapy

scientific article published on 01 April 2020

Sensitivity of subgroup F adenoviruses to interferon

scientific article published in January 1993

Serum levels of inflammatory cytokines in Rift Valley fever patients are indicative of severe disease

scientific article

Single-dose nevirapine exposure affects T cell response and cytokine levels in HIV type 1-infected women

scientific article published on October 2009

Southern African HIV Clinicians Society guidelines for solid organ transplantation in human immunodeficiency virus: An evidence-based framework for human immunodeficiency virus-positive donors and recipients

scientific article published on 15 October 2020

Subgroup F adenovirus growth in foetal intestinal organ cultures

scientific article published in January 1993

T-helper cell responses among HIV-infected children in Soweto, South Africa.

scientific article published on November 2000

The FCGR2C allele that modulated the risk of HIV-1 infection in the Thai RV144 vaccine trial is implicated in HIV-1 disease progression

scientific article published on 19 December 2018

The impact of bone marrow stromal antigen-2 (BST2) gene variants on HIV-1 control in black South African individuals

scientific article published on 30 January 2020

The subgroup F adenoviruses

scientific article published on March 1995

Unusual natural killer cell responses to HIV-1 peptides are associated with protection against maternal-infant transmission of HIV-1

article

Value of cerebrospinal fluid leukocyte aggregation in distinguishing the causes of meningitis in children

scientific article published on 01 January 2000

Variability at the FCGR locus: characterization in Black South Africans and evidence for ethnic variation in and out of Africa.

scientific article published on 17 December 2015

Viral genetic determinants of nonprogressive HIV type 1 subtype C infection in antiretroviral drug-naive children

scientific article published on November 2009

Young age at start of antiretroviral therapy and negative HIV antibody results in HIV-infected children when suppressed

scientific article

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