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List of works by George K. Papadopoulos

A modified flow cytometry method for objective estimation of human CD4+ regulatory T cells (CD4+ Tregs) in peripheral blood, via CD4/CD25/CD45RO/FoxP3 labeling

scientific article published on 30 September 2019

Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2K(d) that stimulates CD8 T cells in insulin-dependent diabetes mellitus

scientific article

Comparative studies on the fine structure of purple membrane from Halobacterium Cutirubrum and Halobacterium Halobium

scientific article published on 01 October 1978

Crossreactivity to vinculin and microbes provides a molecular basis for HLA-based protection against rheumatoid arthritis

scientific article published on 5 May 2015

DRB1*12:01 presents a unique subset of epitopes by preferring aromatics in pocket 9

scientific article published on 23 December 2011

DRB4*01:01 Has a Distinct Motif and Presents a Proinsulin Epitope That Is Recognized in Subjects with Type 1 Diabetes

scientific article published on 19 November 2018

Definition of the peptide binding motif within DRB1*1401 restricted epitopes by peptide competition and structural modeling

scientific article published on 13 February 2008

Determination of the retinal/protein molar ratios for the purple membranes of Halobacterium halobium and Halobacterium cutirubrum

scientific article published on 01 March 1978

Differential binding of pyruvate dehydrogenase complex-E2 epitopes by DRB1*08:01 and DRB1*11:01 Is predicted by their structural motifs and correlates with disease risk

scientific article

Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide

article by Nathan R. Martinez et al published 1 May 2003 in Journal of Clinical Investigation

Discriminative T cell recognition of cross-reactive islet-antigens is associated with HLA-DQ8 transdimer-mediated autoimmune diabetes

scientific article published on 21 August 2019

Dominance of an alternative CLIP sequence in the celiac disease associated HLA-DQ2 molecule

scientific article published on 27 June 2008

Eleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4, and 5 Include Potentially Causal Residues Responsible for the Risk of Childhood Type 1 Diabetes

scientific article published on 24 May 2019

Functional consequences of HLA-DQ8 homozygosity versus heterozygosity for islet autoimmunity in type 1 diabetes

scientific article published on 12 May 2011

Functional inhibition related to structure of a highly potent insulin-specific CD8 T cell clone using altered peptide ligands

scientific article published on January 2008

Gluten-specific T cells cross-react between HLA-DQ8 and the HLA-DQ2α/DQ8β transdimer

scientific article

HLA-DR1001 presents "altered-self" peptides derived from joint-associated proteins by accepting citrulline in three of its binding pockets

scientific article published on October 2010

IL-6-mediated MHC class II induction on RIN-5AH insulinoma cells by IFN-gamma occurs via the G-protein pathway

scientific article published on January 1995

Interplay between genetics and the environment in the development of celiac disease: perspectives for a healthy life.

scientific article

Mechanism of action of prothymosin alpha in the human autologous mixed lymphocyte response

scientific article published in January 1988

Modelling of the MHC II allele I-A(g7) of NOD mouse: pH-dependent changes in specificity at pockets 9 and 6 explain several of the unique properties of this molecule

scientific article published on 01 May 2000

Modulation of T cell response to hGAD65 peptide epitopes

scientific article

Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.

scientific article published on 11 August 2017

Molecular properties of HLA-DQ alleles conferring susceptibility to or protection from insulin-dependent diabetes mellitus: keys to the fate of islet beta-cells

scientific article

Motifs of Three HLA-DQ Amino Acid Residues (α44, β57, β135) Capture Full Association with the Risk of Type 1 Diabetes in DQ2 and DQ8 Children

scientific article published on 03 April 2020

Mutational analysis of critical residues determining antigen presentation and activation of HLA-DQ0602 restricted T-cell clones

scientific article

Novel structural features of the human histocompatibility molecules HLA-DQ as revealed by modeling based on the published structure of the related molecule HLA-DR

scientific article published on 01 September 1996

Orientations of the retinyl and the heme chromophores in the brown membrane of Halobacterium halobium

scientific article published on 01 October 1981

Peptide analysis, stability studies, and structural modeling explain contradictory peptide motifs and unique properties of the NOD mouse MHC class II molecule H2-A(g7).

scientific article published on August 2002

RGD sequences in several receptor proteins: novel cell adhesion function of receptors?

scientific article published on 01 February 1998

Regulation of catalytic behaviour of hydrolases through interactions with functionalized carbon-based nanomaterials

article published in 2012

Response to commentary by Pujol-Borrell and Bottazzo

scientific article published on 01 May 1989

Role of cytokines in the pathogenesis of anemia of chronic disease in rheumatoid arthritis

scientific article published on 01 August 1999

Soluble interleukin 2 receptor molecules in the serum of patients with autoimmune diseases

scientific article published on 01 March 1989

Specific monoclonal antibodies against the surface of rat islet beta cells

scientific article published on January 2002

Structural analysis of two HLA-DR-presented autoantigenic epitopes: crucial role of peripheral but not central peptide residues for T-cell receptor recognition

scientific article published on 01 October 2000

T-cell recognition of HLA-DQ2-bound gluten peptides can be influenced by an N-terminal proline at p-1.

scientific article published on 16 February 2005

The binding of antigenic peptides to HLA-DR is influenced by interactions between pocket 6 and pocket 9.

scientific article

The destructive action of IL-1alpha and IL-1beta in IDDM is a multistage process: evidence and confirmation by apoptotic studies, induction of intermediates and electron microscopy.

scientific article published on January 1999

The increased ability to present citrullinated peptides is not unique to HLA-SE molecules: arginine-to-citrulline conversion also enhances peptide affinity for HLA-DQ molecules

scientific article published on 3 November 2016

The spectrum of HLA-DQ and HLA-DR alleles, 2006: a listing correlating sequence and structure with function

scientific article published on 12 May 2007

Trans heterodimer between two non-arthritis-associated HLA alleles can predispose to arthritis in humanized mice

scientific article

Type 1 diabetes as an autoimmune disease: the evidence

scientific article published on 6 April 2014

Type 1 diabetes-associated HLA-DQ8 transdimer accommodates a unique peptide repertoire

scientific article

Unique peptide binding characteristics of the disease-associated DQ(alpha 1*0501, beta 1*0201) vs the non-disease-associated DQ(alpha 1*0201, beta 1*0202) molecule

scientific article published on 01 January 1997

Use of MHC II structural features in the design of vaccines for organ-specific autoimmune diseases

scientific article published on January 2009

Zinc transporter 8 autoantibodies and their association with SLC30A8 and HLA-DQ genes differ between immigrant and Swedish patients with newly diagnosed type 1 diabetes in the Better Diabetes Diagnosis study

scientific article

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