List of works - Sandro Keller

(Coumarin-4-yl)methyl esters as highly efficient, ultrafast phototriggers for protons and their application to acidifying membrane surfaces.

scientific article published in February 2005

A caged doxycycline analogue for photoactivated gene expression.

scientific article published in March 2006

A critical reassessment of penetratin translocation across lipid membranes

scientific article published on 22 July 2005

A fluorinated detergent for membrane-protein applications

scientific article published on 09 March 2015

A minimal helical-hairpin motif provides molecular-level insights into misfolding and pharmacological rescue of CFTR

scholarly article published 2018

A myomesin mutation associated with hypertrophic cardiomyopathy deteriorates dimerisation properties.

scientific article published on 20 January 2011

A network of coiled-coil associations derived from synthetic GCN4 leucine-zipper arrays.

scientific article published in January 2007

A quantitative model describing the selective solubilization of membrane domains.

scientific article published in August 2005

A simple fluorescence-spectroscopic membrane translocation assay.

scientific article published in March 2007

Aggregation Behavior of pHLIP in Aqueous Solution at Low Concentrations: A Fluorescence Study

scientific article published on 29 June 2018

Alpha-helical transmembrane peptides: a "divide and conquer" approach to membrane proteins.

scientific article published on January 2010

Amyloid precursor protein dimerization and synaptogenic function depend on copper binding to the growth factor-like domain

scientific article

Analysis of selected and designed chimeric D- and L-α-helix assemblies

scientific article

Auto-inhibitory effects of an IQ motif on protein structure and function.

scientific article

Automated analysis of calorimetric demicellization titrations.

scientific article

Automated circular dichroism spectroscopy for medium-throughput analysis of protein conformation

scientific article published on 18 January 2013

Biocalorimetry

scientific article published on 01 April 2015

Caged capsaicins: New tools for the examination of TRPV1 channels in somatosensory neurons

scientific article published on 01 January 2007

Calmodulin-dependent activation and inactivation of anoctamin calcium-gated chloride channels

scientific journal article

Calorimetric Quantification of Cyclodextrin-Mediated Detergent Extraction for Membrane-Protein Reconstitution.

scientific article

Calorimetric quantification of linked equilibria in cyclodextrin/lipid/detergent mixtures for membrane-protein reconstitution

scientific article published on 10 January 2015

Carbon's Three-Center, Four-Electron Tetrel Bond, Treated Experimentally

scientific article published on 07 December 2018

Characterising protein/detergent complexes by triple-detection size-exclusion chromatography.

scientific article published on 15 February 2016

Characterization of membrane proteins in isolated native cellular membranes by dynamic nuclear polarization solid-state NMR spectroscopy without purification and reconstitution.

scientific article

Conformational Dynamics Govern the Free-Energy Landscape of a Membrane-Interacting Protein

scientific article published on 26 September 2018

Copper and zinc ions govern the trans-directed dimerization of APP family members in multiple ways

scientific article published on 06 June 2019

Corrigendum: Multiple Multidentate Halogen Bonding in Solution, in the Solid State, and in the (Calculated) Gas Phase

scientific article published on 06 October 2015

Coumarin-based octopamine phototriggers and their effects on an insect octopamine receptor.

scientific article published on 6 June 2012

Diastereomeric Cyclopentane-Based Maltosides (CPMs) as Tools for Membrane Protein Study

scientific article published on 14 December 2020

Dipalmitoylation of a cellular uptake-mediating apolipoprotein E-derived peptide as a promising modification for stable anchorage in liposomal drug carriers.

scientific article

Dissecting Nanosecond Dynamics in Membrane Proteins with Dipolar Relaxation upon Tryptophan Photoexcitation.

scientific article published on 13 April 2018

Distinct binding properties distinguish LQ-type calmodulin-binding domains in cyclic nucleotide-gated channels.

scientific article published on 25 March 2011

Extra-cavity effect in cyclodextrin/surfactant complexation.

scientific article published on 23 April 2018

Fast Collisional Lipid Transfer Among Polymer-Bounded Nanodiscs

scientific article published on 5 April 2017

Fast and Robust Quantification of Detergent Micellization Thermodynamics from Isothermal Titration Calorimetry

scientific article published on 27 December 2019

Filter gate closure inhibits ion but not water transport through potassium channels

scientific article published on 10 June 2013

Fluorinated diglucose detergents for membrane-protein extraction

scientific article published on 30 May 2018

Formation of Lipid-Bilayer Nanodiscs by Diisobutylene/Maleic Acid (DIBMA) Copolymer

scientific article

High-precision isothermal titration calorimetry with automated peak-shape analysis.

scientific article

How membrane partitioning modulates receptor activation: parallel versus serial effects of hydrophobic ligands.

scientific article published on December 2013

Human essential myosin light chain isoforms revealed distinct myosin binding, sarcomeric sorting, and inotropic activity

scientific article

Hybrid Double-Chain Maltose-Based Detergents: Synthesis and Colloidal and Biochemical Evaluation

scientific article published on 27 August 2019

Hydrogenated Diglucose Detergents for Membrane-Protein Extraction and Stabilization

scientific article published on 14 March 2019

Impact of urea on detergent micelle properties.

scientific article published on 24 June 2013

Influence of Mg2+ and Ca2+ on nanodisc formation by diisobutylene/maleic acid (DIBMA) copolymer

scientific article published on 13 March 2019

Influence of lipid bilayer properties on nanodisc formation mediated by styrene/maleic acid copolymers.

scientific article published on 29 July 2016

Integration and global analysis of isothermal titration calorimetry data for studying macromolecular interactions

scientific article

Interaction of W-substituted analogs of cyclo-RRRWFW with bacterial lipopolysaccharides: the role of the aromatic cluster in antimicrobial activity.

scientific article

Journal of Membrane Biology: Biophysics

scientific article published on 20 April 2016

Lipid Membranes and Reactions at Lipid Interfaces: Theory, Experiments, and Applications

scientific article published on 29 June 2018

Membrane Activity of LL-37 Derived Antimicrobial Peptides against Enterococcus hirae: Superiority of SAAP-148 over OP-145

scientific article published in 2022

Membrane partitioning and translocation studied by isothermal titration calorimetry

scientific article published in January 2013

Mia40-dependent oxidation of cysteines in domain I of Ccs1 controls its distribution between mitochondria and the cytosol ⬇️

scientific article published on August 24, 2011

Micellar and biochemical properties of a propyl-ended fluorinated surfactant designed for membrane-protein study

scientific article published on 03 January 2015

Mistic's membrane association and its assistance in overexpression of a human GPCR are independent processes

scientific article

Model-Free Analysis of Critical Micellar Concentrations for Detecting Demixing in Surfactant Mixtures

scientific article

Modulating bilayer mechanical properties to promote the coupled folding and insertion of an integral membrane protein

scientific article published on 29 May 2015

Molecular Basis for Association of PIPKI -p90 with Clathrin Adaptor AP-2

scientific article

Monitoring lipid membrane translocation of sodium dodecyl sulfate by isothermal titration calorimetry.

scientific article published in February 2006

Multiple Multidentate Halogen Bonding in Solution, in the Solid State, and in the (Calculated) Gas Phase

scientific article published on 2 September 2015

Mutations of ventricular essential myosin light chain disturb myosin binding and sarcomeric sorting.

scientific article

Nanoparticle self-assembly in mixtures of phospholipids with styrene/maleic acid copolymers or fluorinated surfactants

scientific article published on 24 November 2015

Nonlinear least-squares data fitting in Excel spreadsheets.

scientific article

Oxoanion binding to a cyclic pseudopeptide containing 1,4-disubstituted 1,2,3-triazole moieties

scientific article published on 2 November 2016

Periplasmic loop P2 of the MalF subunit of the maltose ATP binding cassette transporter is sufficient to bind the maltose binding protein MalE.

scientific article

Pharmacological interference with protein-protein interactions mediated by coiled-coil motifs.

scientific article published on January 2008

Polar interactions trump hydrophobicity in stabilizing the self-inserting membrane protein Mistic

scientific article

Preparation of ready-to-use small unilamellar phospholipid vesicles by ultrasonication with a beaker resonator

scientific article published on 21 February 2015

Proline-rich sequence recognition: II. Proteomics analysis of Tsg101 ubiquitin-E2-like variant (UEV) interactions

scientific article

Protein folding in membranes.

scientific article published on 27 January 2010

Quantification of Millisecond Protein-Folding Dynamics in Membrane-Mimetic Environments by Single-Molecule Förster Resonance Energy Transfer Spectroscopy.

scientific article

Quantifying high-affinity binding of hydrophobic ligands by isothermal titration calorimetry.

scientific article

Rationalizing Steroid Interactions with Lipid Membranes: Conformations, Partitioning, and Kinetics

scientific article published on 14 August 2018

Real-time Visualization of Phospholipid Degradation by Outer Membrane Phospholipase A using High-Speed Atomic Force Microscopy.

scientific article published on 7 March 2017

Real-time monitoring of membrane-protein reconstitution by isothermal titration calorimetry

scientific article published on 24 December 2013

Revisiting the optimal cvalue for isothermal titration calorimetry ⬇️

scientific article published on July 30, 2011

Ring A of nukacin ISK-1: a lipid II-binding motif for type-A(II) lantibiotic

scientific article published on 17 February 2012

Role of Coulombic Repulsion in Collisional Lipid Transfer Among SMA(2:1)-Bounded Nanodiscs

scientific article published on 5 March 2018

Selective identification of cooperatively binding fragments in a high-throughput ligation assay enables development of a picomolar caspase-3 inhibitor.

scientific article published in January 2009

Self-assembly thermodynamics of pH-responsive amino-acid-based polymers with a nonionic surfactant.

scientific article published on 18 September 2014

Sequence-specific dimerization of a transmembrane helix in amphipol A8-35.

scientific article

Short cationic antimicrobial peptides interact with ATP.

scientific article published on 26 July 2010

Single-experiment displacement assay for quantifying high-affinity binding by isothermal titration calorimetry.

scientific article published on 13 November 2014

Slow Interconversion in a Heterogeneous Unfolded-State Ensemble of Outer-Membrane Phospholipase A.

scientific article published on 16 June 2017

Small-molecule inhibitors of AF6 PDZ-mediated protein-protein interactions.

scientific article

Solubilization of Membrane Proteins into Functional Lipid-Bilayer Nanodiscs Using a Diisobutylene/Maleic Acid Copolymer

scientific article published on 12 January 2017

Structural Thermodynamics of myr-Src(2-19) Binding to Phospholipid Membranes.

scientific article published on August 2015

Structural and molecular comparison of bacterial and eukaryotic trigger factors

scientific article published on 6 September 2017

Structural determinants of the interaction between influenza A virus matrix protein M1 and lipid membranes

scientific article published on 20 March 2019

Structure-activity relationships of the antimicrobial peptide gramicidin S and its analogs: aqueous solubility, self-association, conformation, antimicrobial activity and interaction with model lipid membranes

scientific article published on 02 January 2014

The Role of Plastidic Trigger Factor Serving Protein Biogenesis in Green Algae and Land Plants

article

The mechanism of denaturation and the unfolded state of the α-helical membrane-associated protein Mistic.

scientific article

Thermodynamics of nanodisc formation mediated by styrene/maleic acid (2:1) copolymer

scientific article published on 14 September 2017

Ultrafast Protein Folding in Membrane-Mimetic Environments.

scientific article published on 8 November 2017

Uptake and release protocol for assessing membrane binding and permeation by way of isothermal titration calorimetry

scientific article published on 01 January 2007

VIPP1 rods engulf membranes containing phosphatidylinositol phosphates.

scientific article published on 19 June 2019

List of works by Sandro Keller

(Coumarin-4-yl)methyl esters as highly efficient, ultrafast phototriggers for protons and their application to acidifying membrane surfaces.

A caged doxycycline analogue for photoactivated gene expression.

A critical reassessment of penetratin translocation across lipid membranes

A fluorinated detergent for membrane-protein applications

A minimal helical-hairpin motif provides molecular-level insights into misfolding and pharmacological rescue of CFTR

A myomesin mutation associated with hypertrophic cardiomyopathy deteriorates dimerisation properties.

A network of coiled-coil associations derived from synthetic GCN4 leucine-zipper arrays.

A quantitative model describing the selective solubilization of membrane domains.

A simple fluorescence-spectroscopic membrane translocation assay.

Aggregation Behavior of pHLIP in Aqueous Solution at Low Concentrations: A Fluorescence Study

Alpha-helical transmembrane peptides: a "divide and conquer" approach to membrane proteins.

Amyloid precursor protein dimerization and synaptogenic function depend on copper binding to the growth factor-like domain

Analysis of selected and designed chimeric D- and L-α-helix assemblies

Auto-inhibitory effects of an IQ motif on protein structure and function.

Automated analysis of calorimetric demicellization titrations.

Automated circular dichroism spectroscopy for medium-throughput analysis of protein conformation

Biocalorimetry

Caged capsaicins: New tools for the examination of TRPV1 channels in somatosensory neurons

Calmodulin-dependent activation and inactivation of anoctamin calcium-gated chloride channels

Calorimetric Quantification of Cyclodextrin-Mediated Detergent Extraction for Membrane-Protein Reconstitution.

Calorimetric quantification of linked equilibria in cyclodextrin/lipid/detergent mixtures for membrane-protein reconstitution

Carbon's Three-Center, Four-Electron Tetrel Bond, Treated Experimentally

Characterising protein/detergent complexes by triple-detection size-exclusion chromatography.

Characterization of membrane proteins in isolated native cellular membranes by dynamic nuclear polarization solid-state NMR spectroscopy without purification and reconstitution.

Conformational Dynamics Govern the Free-Energy Landscape of a Membrane-Interacting Protein

Copper and zinc ions govern the trans-directed dimerization of APP family members in multiple ways

Corrigendum: Multiple Multidentate Halogen Bonding in Solution, in the Solid State, and in the (Calculated) Gas Phase

Coumarin-based octopamine phototriggers and their effects on an insect octopamine receptor.

Diastereomeric Cyclopentane-Based Maltosides (CPMs) as Tools for Membrane Protein Study

Dipalmitoylation of a cellular uptake-mediating apolipoprotein E-derived peptide as a promising modification for stable anchorage in liposomal drug carriers.

Dissecting Nanosecond Dynamics in Membrane Proteins with Dipolar Relaxation upon Tryptophan Photoexcitation.

Distinct binding properties distinguish LQ-type calmodulin-binding domains in cyclic nucleotide-gated channels.

Extra-cavity effect in cyclodextrin/surfactant complexation.

Fast Collisional Lipid Transfer Among Polymer-Bounded Nanodiscs

Fast and Robust Quantification of Detergent Micellization Thermodynamics from Isothermal Titration Calorimetry

Filter gate closure inhibits ion but not water transport through potassium channels

Fluorinated diglucose detergents for membrane-protein extraction

Formation of Lipid-Bilayer Nanodiscs by Diisobutylene/Maleic Acid (DIBMA) Copolymer

High-precision isothermal titration calorimetry with automated peak-shape analysis.

How membrane partitioning modulates receptor activation: parallel versus serial effects of hydrophobic ligands.

Human essential myosin light chain isoforms revealed distinct myosin binding, sarcomeric sorting, and inotropic activity

Hybrid Double-Chain Maltose-Based Detergents: Synthesis and Colloidal and Biochemical Evaluation

Hydrogenated Diglucose Detergents for Membrane-Protein Extraction and Stabilization

Impact of urea on detergent micelle properties.

Influence of Mg2+ and Ca2+ on nanodisc formation by diisobutylene/maleic acid (DIBMA) copolymer

Influence of lipid bilayer properties on nanodisc formation mediated by styrene/maleic acid copolymers.

Integration and global analysis of isothermal titration calorimetry data for studying macromolecular interactions

Interaction of W-substituted analogs of cyclo-RRRWFW with bacterial lipopolysaccharides: the role of the aromatic cluster in antimicrobial activity.

Journal of Membrane Biology: Biophysics

Lipid Membranes and Reactions at Lipid Interfaces: Theory, Experiments, and Applications

Membrane Activity of LL-37 Derived Antimicrobial Peptides against Enterococcus hirae: Superiority of SAAP-148 over OP-145

Membrane partitioning and translocation studied by isothermal titration calorimetry

Mia40-dependent oxidation of cysteines in domain I of Ccs1 controls its distribution between mitochondria and the cytosol ⬇️

Micellar and biochemical properties of a propyl-ended fluorinated surfactant designed for membrane-protein study

Mistic's membrane association and its assistance in overexpression of a human GPCR are independent processes

Model-Free Analysis of Critical Micellar Concentrations for Detecting Demixing in Surfactant Mixtures

Modulating bilayer mechanical properties to promote the coupled folding and insertion of an integral membrane protein

Molecular Basis for Association of PIPKI -p90 with Clathrin Adaptor AP-2

Monitoring lipid membrane translocation of sodium dodecyl sulfate by isothermal titration calorimetry.

Multiple Multidentate Halogen Bonding in Solution, in the Solid State, and in the (Calculated) Gas Phase

Mutations of ventricular essential myosin light chain disturb myosin binding and sarcomeric sorting.

Nanoparticle self-assembly in mixtures of phospholipids with styrene/maleic acid copolymers or fluorinated surfactants

Nonlinear least-squares data fitting in Excel spreadsheets.

Oxoanion binding to a cyclic pseudopeptide containing 1,4-disubstituted 1,2,3-triazole moieties

Periplasmic loop P2 of the MalF subunit of the maltose ATP binding cassette transporter is sufficient to bind the maltose binding protein MalE.

Pharmacological interference with protein-protein interactions mediated by coiled-coil motifs.

Polar interactions trump hydrophobicity in stabilizing the self-inserting membrane protein Mistic

Preparation of ready-to-use small unilamellar phospholipid vesicles by ultrasonication with a beaker resonator

Proline-rich sequence recognition: II. Proteomics analysis of Tsg101 ubiquitin-E2-like variant (UEV) interactions

Protein folding in membranes.

Quantification of Millisecond Protein-Folding Dynamics in Membrane-Mimetic Environments by Single-Molecule Förster Resonance Energy Transfer Spectroscopy.

Quantifying high-affinity binding of hydrophobic ligands by isothermal titration calorimetry.

Rationalizing Steroid Interactions with Lipid Membranes: Conformations, Partitioning, and Kinetics

Real-time Visualization of Phospholipid Degradation by Outer Membrane Phospholipase A using High-Speed Atomic Force Microscopy.

Real-time monitoring of membrane-protein reconstitution by isothermal titration calorimetry

Revisiting the optimal cvalue for isothermal titration calorimetry ⬇️

Ring A of nukacin ISK-1: a lipid II-binding motif for type-A(II) lantibiotic

Role of Coulombic Repulsion in Collisional Lipid Transfer Among SMA(2:1)-Bounded Nanodiscs

Selective identification of cooperatively binding fragments in a high-throughput ligation assay enables development of a picomolar caspase-3 inhibitor.