List of works - Gianluigi Mazzoccoli

A Lipidomic Signature Complements Stemness Features Acquisition in Liver Cancer Cells

scientific article published on 10 November 2020

A Multi-Layered Study on Harmonic Oscillations in Mammalian Genomics and Proteomics

scientific article published on 17 September 2019

A Timeless Link Between Circadian Patterns and Disease.

scientific article published on 12 December 2015

A linear mixed model approach to compare the evolution of multiple biological rhythms

scientific article published on 19 December 2012

A method to evaluate dynamics and periodicity of hormone secretion.

scientific article

A possible mechanism for altered immune response in the elderly

scientific article published on July 2010

A primary tumor gene expression signature identifies a crucial role played by tumor stroma myofibroblasts in lymph node involvement in oral squamous cell carcinoma

scientific article published on 5 September 2017

A ticking clock links metabolic pathways and organ systems function in health and disease.

scientific article published on 04 April 2013

A timetable of 24-hour patterns for human lymphocyte subpopulations

scientific article published on 01 July 2011

A unifying working hypothesis for juvenile polyposis syndrome and Ménétrier's disease: Specific localization or concomitant occurrence of a separate entity?

scientific article published on 27 June 2012

ARNTL2 and SERPINE1: potential biomarkers for tumor aggressiveness in colorectal cancer.

scientific article

Age-dependent association of exposure to television screen with children's urinary melatonin excretion?

scientific article published on 01 February 2006

Age-related changes of neuro-endocrine-immune interactions in healthy humans

scientific article published on 01 October 1997

Aging related changes of circadian rhythmicity of cytotoxic lymphocyte subpopulations.

scientific article published on 25 May 2010

Aging signaling pathways and circadian clock-dependent metabolic derangements

scientific article

Alteration of circadian rhythmicity of CD3+CD4+ lymphocyte subpopulation in healthy aging

scientific article published on 01 July 2011

Alteration of hypothalamic-pituitary-thyroid axis function in non-small-cell lung cancer patients.

scientific article published on 23 August 2011

Altered expression of the clock gene machinery in kidney cancer patients

article

Altered time structure of neuro-endocrine-immune system function in lung cancer patients.

scientific article

Amphiregulin activates human hepatic stellate cells and is upregulated in non alcoholic steatohepatitis

scientific article published on 6 March 2015

An association study between epicardial fat thickness and cognitive impairment in the elderly

scientific article published in November 2014

Analysis of MTNR1B gene polymorphisms in relationship with IRS2 gene variants, epicardial fat thickness, glucose homeostasis and cognitive performance in the elderly.

scientific article

Analysis of clock gene-miRNA correlation networks reveals candidate drivers in colorectal cancer.

scientific article published on 14 June 2016

Anti-correlation between longevity gene SirT1 and Notch signaling in ascending aorta biopsies from patients with bicuspid aortic valve disease

scientific article

Anti-tumor necrosis factor-α therapy and changes of flow-mediated vasodilatation in psoriatic and rheumatoid arthritis patients

scientific article published on 16 September 2010

Antiphase signalling in the neuroendocrine-immune system in healthy humans

scientific article published on 08 April 2011

Arterial endothelial dysfunction and idiopathic deep venous thrombosis.

scientific article published on October 2011

Aryl Hydrocarbon Receptor Role in Co-Ordinating SARS-CoV-2 Entry and Symptomatology: Linking Cytotoxicity Changes in COVID-19 and Cancers; Modulation by Racial Discrimination Stress

scientific article published on 27 August 2020

Aryl hydrocarbon receptor-fibroblast growth factor 21 dissociation of fatty liver from insulin resistance: A timely matter?

scientific article

Association study of a polymorphism in clock gene PERIOD3 and risk of inflammatory bowel disease

scientific article published on 10 August 2012

Behçet syndrome: from pathogenesis to novel therapies

scientific article

Biology, Epidemiology, Clinical Aspects of Hepatocellular Carcinoma and the Role of Sorafenib.

scientific article

Body composition: Where and when.

scientific article published on 31 October 2015

Caloric restriction and aging stem cells: the stick and the carrot?

scientific article

Cardioprotective mIGF-1/SIRT1 signaling induces hypertension, leukocytosis and fear response in mice

scientific article published on June 2012

Change of γδTCR-expressing T cells in healthy aging

scientific article published on 01 January 2011

Chronodisruption in lung cancer and possible therapeutic approaches.

scientific article published on 27 August 2011

Circadian aspects of growth hormone-insulin-like growth factor axis function in patients with lung cancer

scientific article published on 19 May 2011

Circadian clock circuitry in colorectal cancer

scientific article published on April 2014

Circadian rhythmicity of lymphocyte subpopulations and relationship with neuro-endocrine system.

scientific article published on July 2010

Circadian transcriptome analysis in human fibroblasts from Hunter syndrome and impact of iduronate-2-sulfatase treatment

scientific article

Circadian variations of cortisol, melatonin and lymphocyte subpopulations in geriatric age.

scientific article published in January 2010

Circasemidian rather than circadian variation of circulating osteoprotegerin in clinical health

scientific article published on October 2005

Clock gene expression in human and mouse hepatic models shows similar periodicity but different dynamics of variation

scientific article published in January 2016

Clock gene expression in mouse kidney and testis: analysis of periodical and dynamical patterns.

scientific article published in April 2012

Clock gene expression levels and relationship with clinical and pathological features in colorectal cancer patients.

scientific article published in December 2011

Clock genes-dependent acetylation of complex I sets rhythmic activity of mitochondrial OxPhos.

scientific article

Clock-genes and mitochondrial respiratory activity: Evidence of a reciprocal interplay

scientific article published on 6 April 2016

Colorectal cancer prognosis and PPARδ/β expression in the tumor microenvironment

scientific article published on 26 November 2013

Comparison of circadian characteristics for cytotoxic lymphocyte subsets in non-small cell lung cancer patients versus controls

scientific article published on 11 September 2011

Computed-tomographic-guided biopsy of thoracic nodules: a revision of 583 lesions.

scientific article published in November 2007

Concomitant evaluation of flow-mediated vasodilation and epicardial fat thickness in idiopathic deep venous thrombosis.

scientific article published in January 2012

Continuity of care: an Italian clinical experience

scientific article published on 6 July 2012

Crosstalk between the circadian clock circuitry and the immune system.

scientific article published on 22 May 2013

DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression

scientific article published on 15 January 2016

DNA methyltransferases 1 and 3b expression in Huh-7 cells expressing HCV core protein of different genotypes

scientific article published on 24 April 2012

Decreased serum levels of insulin-like growth factor (IGF)-I in patients with lung cancer: temporal relationship with growth hormone (GH) levels

scientific article published on 01 March 1999

Deregulated expression of cryptochrome genes in human colorectal cancer

scientific article

Determination of whole body circadian phase in lung cancer patients: melatonin vs. cortisol

scientific article published on 13 October 2011

Differential patterns in the periodicity and dynamics of clock gene expression in mouse liver and stomach

scientific article published on 06 November 2012

Digital ulcers in scleroderma patients: A retrospective observational study

scientific article published on 18 December 2015

Effect of naive and cancer-educated fibroblasts on colon cancer cell circadian growth rhythm

scientific article published on 27 April 2020

Effects of hypercapnia on peripheral vascular reactivity in elderly patients with acute exacerbation of chronic obstructive pulmonary disease

scientific article

Epicardial adipose tissue and idiopathic deep venous thrombosis: An association study

scientific article published on 12 June 2012

Exploitation of host clock gene machinery by hepatitis viruses B and C.

scientific article published on December 2013

Friend or foe?: The tumour microenvironment dilemma in colorectal cancer

scientific article published on 15 November 2016

Functional Impact of Autophagy-Related Genes on the Homeostasis and Dynamics of Pancreatic Cancer Cell Lines

scientific article published on May 2015

Glioma: Tryptophan Catabolite and Melatoninergic Pathways Link microRNA, 14-3- 3, Chromosome 4q35, Epigenetic Processes and other Glioma Biochemical Changes.

scientific article

Hepato-systemic gradient of carbon monoxide in cirrhosis.

scientific article published on 21 November 2011

High-confidence assessment of functional impact of human mitochondrial non-synonymous genome variations by APOGEE

scientific article

Histone variants and lipid metabolism

scientific article

Hormone and cytokine circadian alteration in non-small cell lung cancer patients

scientific article published on 01 July 2012

Hypothalamus-hypophysis-thyroid axis function in healthy aging.

scientific article published on October 2010

Idiopathic deep venous thrombosis and arterial endothelial dysfunction in the elderly

scientific article

Idiopathic deep venous thrombosis and epicardial fat thickness: The age, gender and obesity connection

Immune system alterations in lung cancer patients

scientific article published on 01 May 2003

Immunopathogenetic and pharmacological aspects of interstitial lung diseases

scientific article published on 01 October 2010

Immunopositivity for histone macroH2A1 isoforms marks steatosis-associated hepatocellular carcinoma

scientific article published in 2013

Influence of the Gly1057Asp variant of the insulin receptor substrate 2 (IRS2) on insulin resistance and relationship with epicardial fat thickness in the elderly.

scientific article published on 25 September 2012

Intermediate neoadjuvant radiotherapy for T3 low/middle rectal cancer: postoperative outcomes of a non-controlled clinical trial.

scientific article

Interplay between SOX9, β-catenin and PPARγ activation in colorectal cancer.

scientific article published on 11 April 2013

Klotho at the Edge of Alzheimer's Disease and Senile Depression

scientific article published on 05 July 2018

Left Ventricular Hypertrophy: Roles of Mitochondria CYP1B1 and Melatonergic Pathways in Co-Ordinating Wider Pathophysiology

scientific article published on 20 August 2019

Lymphocyte subpopulations anomalies in lung cancer patients and relationship to the stage of disease

scientific article published on 01 May 1999

Management strategies for hepatocellular carcinoma: old certainties and new realities.

scientific article

Melatonin and Sirtuins in Buccal Epithelium: Potential Biomarkers of Aging and Age-Related Pathologies

scientific article published on 30 October 2020

Melatonin and cortisol serum levels in lung cancer patients at different stages of disease.

scientific article published on 25 May 2005

Mirna expression profiles identify drivers in colorectal and pancreatic cancers.

scientific article

Molecular bases of circadian rhythmicity in renal physiology and pathology.

scientific article published on 30 July 2013

Molecular dynamics recipes for genome research.

scientific article published on 18 February 2017

Morphofunctional and signaling molecules overlap of the pineal gland and thymus: role and significance in aging

scientific article

Multifaceted enrichment analysis of RNA-RNA crosstalk reveals cooperating micro-societies in human colorectal cancer

scientific article

Mutual antagonism between circadian protein period 2 and hepatitis C virus replication in hepatocytes

scientific article

Neuro-endocrine correlations of hypothalamic-pituitary-thyroid axis in healthy humans.

scientific article published in April 2011

Neuroendocrine alterations in lung cancer patients.

scientific article published in February 2003

Neuroendocrine-immune interactions in healthy aging

scientific article published in January 2011

Non invasive continuous hemodynamic evaluation of cirrhotic patients after postural challenge ⬇️

scientific article published on April 27, 2012

Non-alcoholic fatty liver disease: the role of nuclear receptors and circadian rhythmicity.

scientific article published on 09 April 2014

PPARs Signaling and Cancer in the Gastrointestinal System

scientific article published on 17 September 2012

Peroxisome proliferator-activated receptor gamma and regulations by the ubiquitin-proteasome system in pancreatic cancer

scientific article published on 19 September 2012

Peroxisome proliferator-activated receptor γ-mediated induction of microRNA-145 opposes tumor phenotype in colorectal cancer

scientific article published on 11 March 2014

Prolonged remission of neuro-Behcet disease following autologous transplantation

scientific article published in January 2007

Proteomic screening identifies calreticulin as a miR-27a direct target repressing MHC class I cell surface exposure in colorectal cancer

scientific article published on 25 February 2016

Pulmonary embolism: a late complication of a correctly positioned occluder device for patent foramen ovale

scientific article published in October 2008

REV-ERBα and the clock gene machinery in mouse peripheral tissues: a possible role as a synchronizing hinge.

scientific article published in April 2012

Redox homeostasis and epigenetics in non-alcoholic fatty liver disease (NAFLD).

scientific article published on January 2013

Reply to "Letter to the editor: The effect of autonomic nervous system on the association between epicardial adipose tissue and cognitive function"

scientific article published on 01 April 2015

Rheumatoid arthritis and the biological clock.

scientific article published on 31 March 2014

SIRT1 and circadian gene expression in pancreatic ductal adenocarcinoma: Effect of starvation.

scientific article

SIRT1 and the clock gene machinery in colorectal cancer.

scientific article

SIRT1-metabolite binding histone macroH2A1.1 protects hepatocytes against lipid accumulation

scientific article published on January 2014

Stage dependent destructuration of neuro-endocrine-immune system components in lung cancer patients

scientific article published on 29 December 2010

Stem cell autograft and allograft in autoimmune diseases

scientific article

Sympathetic nervous system catecholamines and neuropeptide Y neurotransmitters are upregulated in human NAFLD and modulate the fibrogenic function of hepatic stellate cells

scientific article

Systematic analysis of circadian genes using genome-wide cDNA microarrays in the inflammatory bowel disease transcriptome

scientific article published on 14 July 2015

The Circadian Clock, the Immune System, and Viral Infections: The Intricate Relationship Between Biological Time and Host-Virus Interaction

scientific article published on 27 January 2020

The Role of Prenatal Melatonin in the Regulation of Childhood Obesity

scientific article published on 05 April 2020

The TRPA1 channel is a cardiac target of mIGF-1/SIRT1 signaling

scientific article published on 8 August 2014

The biological clock and the molecular basis of lysosomal storage diseases.

scientific article published on 13 January 2015

The circadian clock and the hypoxic response pathway in kidney cancer.

scientific article published on 14 August 2013

The circadian clock circuitry and the AHR signaling pathway in physiology and pathology.

scientific article published on 21 February 2013

The expression of leucine-rich repeat gene family members in colorectal cancer

scientific article

The hypothalamic-pituitary-thyroid axis and melatonin in humans: possible interactions in the control of body temperature.

scientific article published in October 2004

The miR-27a-calreticulin axis affects drug-induced immunogenic cell death in human colorectal cancer cells

scientific article published on 25 February 2016

The reciprocal interplay between TNFα and the circadian clock impacts on cell proliferation and migration in Hodgkin lymphoma cells

scientific article published in Scientific Reports

The synovio-entheseal complex in enthesoarthritis

scientific article

The timing clockwork of life

scientific article published on January 1, 2011

The transcriptional regulators, the immune system and the the circadian clock

scientific article published on 01 January 2013

Time related variations in stem cell harvesting of umbilical cord blood

scientific article published on 24 February 2016

Time-Qualified Patterns of Variation of PPARγ, DNMT1, and DNMT3B Expression in Pancreatic Cancer Cell Lines.

scientific article published on 26 August 2012

Time-related dynamics of variation in core clock gene expression levels in tissues relevant to the immune system.

scientific article published in October 2011

Toll-like receptor 4 modulation influences human neural stem cell proliferation and differentiation

scientific article published on 15 February 2018

[Dyspepsia and Helicobacter pylori]

scientific article published on 01 January 1999

List of works by Gianluigi Mazzoccoli

A Lipidomic Signature Complements Stemness Features Acquisition in Liver Cancer Cells

A Multi-Layered Study on Harmonic Oscillations in Mammalian Genomics and Proteomics

A Timeless Link Between Circadian Patterns and Disease.

A linear mixed model approach to compare the evolution of multiple biological rhythms

A method to evaluate dynamics and periodicity of hormone secretion.

A possible mechanism for altered immune response in the elderly

A primary tumor gene expression signature identifies a crucial role played by tumor stroma myofibroblasts in lymph node involvement in oral squamous cell carcinoma

A ticking clock links metabolic pathways and organ systems function in health and disease.

A timetable of 24-hour patterns for human lymphocyte subpopulations

A unifying working hypothesis for juvenile polyposis syndrome and Ménétrier's disease: Specific localization or concomitant occurrence of a separate entity?

ARNTL2 and SERPINE1: potential biomarkers for tumor aggressiveness in colorectal cancer.

Age-dependent association of exposure to television screen with children's urinary melatonin excretion?

Age-related changes of neuro-endocrine-immune interactions in healthy humans

Aging related changes of circadian rhythmicity of cytotoxic lymphocyte subpopulations.

Aging signaling pathways and circadian clock-dependent metabolic derangements

Alteration of circadian rhythmicity of CD3+CD4+ lymphocyte subpopulation in healthy aging

Alteration of hypothalamic-pituitary-thyroid axis function in non-small-cell lung cancer patients.

Altered expression of the clock gene machinery in kidney cancer patients

Altered time structure of neuro-endocrine-immune system function in lung cancer patients.

Amphiregulin activates human hepatic stellate cells and is upregulated in non alcoholic steatohepatitis

An association study between epicardial fat thickness and cognitive impairment in the elderly

Analysis of MTNR1B gene polymorphisms in relationship with IRS2 gene variants, epicardial fat thickness, glucose homeostasis and cognitive performance in the elderly.

Analysis of clock gene-miRNA correlation networks reveals candidate drivers in colorectal cancer.

Anti-correlation between longevity gene SirT1 and Notch signaling in ascending aorta biopsies from patients with bicuspid aortic valve disease

Anti-tumor necrosis factor-α therapy and changes of flow-mediated vasodilatation in psoriatic and rheumatoid arthritis patients

Antiphase signalling in the neuroendocrine-immune system in healthy humans

Arterial endothelial dysfunction and idiopathic deep venous thrombosis.

Aryl Hydrocarbon Receptor Role in Co-Ordinating SARS-CoV-2 Entry and Symptomatology: Linking Cytotoxicity Changes in COVID-19 and Cancers; Modulation by Racial Discrimination Stress

Aryl hydrocarbon receptor-fibroblast growth factor 21 dissociation of fatty liver from insulin resistance: A timely matter?

Association study of a polymorphism in clock gene PERIOD3 and risk of inflammatory bowel disease

Behçet syndrome: from pathogenesis to novel therapies

Biology, Epidemiology, Clinical Aspects of Hepatocellular Carcinoma and the Role of Sorafenib.

Body composition: Where and when.

Caloric restriction and aging stem cells: the stick and the carrot?

Cardioprotective mIGF-1/SIRT1 signaling induces hypertension, leukocytosis and fear response in mice

Change of γδTCR-expressing T cells in healthy aging

Chronodisruption in lung cancer and possible therapeutic approaches.

Circadian aspects of growth hormone-insulin-like growth factor axis function in patients with lung cancer

Circadian clock circuitry in colorectal cancer

Circadian rhythmicity of lymphocyte subpopulations and relationship with neuro-endocrine system.

Circadian transcriptome analysis in human fibroblasts from Hunter syndrome and impact of iduronate-2-sulfatase treatment

Circadian variations of cortisol, melatonin and lymphocyte subpopulations in geriatric age.

Circasemidian rather than circadian variation of circulating osteoprotegerin in clinical health

Clock gene expression in human and mouse hepatic models shows similar periodicity but different dynamics of variation

Clock gene expression in mouse kidney and testis: analysis of periodical and dynamical patterns.

Clock gene expression levels and relationship with clinical and pathological features in colorectal cancer patients.

Clock genes-dependent acetylation of complex I sets rhythmic activity of mitochondrial OxPhos.

Clock-genes and mitochondrial respiratory activity: Evidence of a reciprocal interplay

Colorectal cancer prognosis and PPARδ/β expression in the tumor microenvironment

Comparison of circadian characteristics for cytotoxic lymphocyte subsets in non-small cell lung cancer patients versus controls

Computed-tomographic-guided biopsy of thoracic nodules: a revision of 583 lesions.

Concomitant evaluation of flow-mediated vasodilation and epicardial fat thickness in idiopathic deep venous thrombosis.

Continuity of care: an Italian clinical experience

Crosstalk between the circadian clock circuitry and the immune system.

DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression

DNA methyltransferases 1 and 3b expression in Huh-7 cells expressing HCV core protein of different genotypes

Decreased serum levels of insulin-like growth factor (IGF)-I in patients with lung cancer: temporal relationship with growth hormone (GH) levels

Deregulated expression of cryptochrome genes in human colorectal cancer

Determination of whole body circadian phase in lung cancer patients: melatonin vs. cortisol

Differential patterns in the periodicity and dynamics of clock gene expression in mouse liver and stomach

Digital ulcers in scleroderma patients: A retrospective observational study

Effect of naive and cancer-educated fibroblasts on colon cancer cell circadian growth rhythm

Effects of hypercapnia on peripheral vascular reactivity in elderly patients with acute exacerbation of chronic obstructive pulmonary disease

Epicardial adipose tissue and idiopathic deep venous thrombosis: An association study

Exploitation of host clock gene machinery by hepatitis viruses B and C.

Friend or foe?: The tumour microenvironment dilemma in colorectal cancer

Functional Impact of Autophagy-Related Genes on the Homeostasis and Dynamics of Pancreatic Cancer Cell Lines

Glioma: Tryptophan Catabolite and Melatoninergic Pathways Link microRNA, 14-3- 3, Chromosome 4q35, Epigenetic Processes and other Glioma Biochemical Changes.

Hepato-systemic gradient of carbon monoxide in cirrhosis.

High-confidence assessment of functional impact of human mitochondrial non-synonymous genome variations by APOGEE

Histone variants and lipid metabolism

Hormone and cytokine circadian alteration in non-small cell lung cancer patients

Hypothalamus-hypophysis-thyroid axis function in healthy aging.

Idiopathic deep venous thrombosis and arterial endothelial dysfunction in the elderly

Idiopathic deep venous thrombosis and epicardial fat thickness: The age, gender and obesity connection

Immune system alterations in lung cancer patients

Immunopathogenetic and pharmacological aspects of interstitial lung diseases

Immunopositivity for histone macroH2A1 isoforms marks steatosis-associated hepatocellular carcinoma

Influence of the Gly1057Asp variant of the insulin receptor substrate 2 (IRS2) on insulin resistance and relationship with epicardial fat thickness in the elderly.