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List of works by Alejandra Tomas

A Targeted RNAi Screen Identifies Endocytic Trafficking Factors that Control GLP-1 Receptor Signaling in Pancreatic Beta Cells.

scientific article

Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells

scientific article published on 20 August 2019

Annexin 11 is required for midbody formation and completion of the terminal phase of cytokinesis

scientific article

Calcium- and cell cycle-dependent association of annexin 11 with the nuclear envelope

scientific article

Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology. ⬇️

scientific article published on 16 January 2018

Control of insulin secretion by GLP-1.

scientific article published in February 2018

Dual effect of cell-cell contact disruption on cytosolic calcium and insulin secretion

scientific article

Dynamin is functionally coupled to insulin granule exocytosis

scientific article published on 11 September 2007

EGF receptor trafficking: consequences for signaling and cancer

scientific article

Effects on pancreatic Beta and other Islet cells of the glucose-dependent insulinotropic polypeptide

scientific article published on 18 November 2019

Erratum. Small Interfering RNA-Mediated Suppression of Proislet Amyloid Polypeptide Expression Inhibits Islet Amyloid Formation and Enhances Survival of Human Islets in Culture. Diabetes 2008;57:3045-3055.

scientific article published on March 2016

Expanded LUXendin Color Palette for GLP1R Detection and Visualization In Vitro and In Vivo

scientific article published on 04 April 2022

Focal adhesion remodeling is crucial for glucose-stimulated insulin secretion and involves activation of focal adhesion kinase and paxillin ⬇️

scientific article

Hepatocyte cholesterol content modulates glucagon receptor signalling

Moesin and cortactin control actin-dependent multivesicular endosome biogenesis

scientific article published on 07 September 2016

Munc 18-1 and granuphilin collaborate during insulin granule exocytosis

scientific article published on 19 January 2008

Novel mechanistic link between focal adhesion remodeling and glucose-stimulated insulin secretion

scientific article published on 2 December 2011

Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist

scientific article published on 30 April 2021

Potent Prearranged Positive Allosteric Modulators of the Glucagon-like Peptide-1 Receptor.

scientific article

Pro-Survival Role of Gelsolin in Mouse -Cells

scientific article published on 01 January 2007

Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells

scientific article

Regulation of insulin secretion by phosphatidylinositol-4,5-bisphosphate

scientific article

Regulation of pancreatic -cell insulin secretion by actin cytoskeleton remodelling: role of gelsolin and cooperation with the MAPK signalling pathway

scientific article published on 25 April 2006

Role of the Rho-ROCK (Rho-associated kinase) signaling pathway in the regulation of pancreatic beta-cell function

scientific article published on 23 December 2008

Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture

scientific article published on 11 August 2008

Stress reveals new destination for EGF receptor

scientific article published on 29 September 2015

Stress-specific p38 MAPK activation is sufficient to drive EGFR endocytosis but not its nuclear translocation

scientific article published on 23 June 2017

Targeting GLP-1 receptor trafficking to improve agonist efficacy.

scientific article published on 23 April 2018

The Zinc Transporter Slc30a8/ZnT8 Is Required in a Subpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon Secretion

scientific article

WASH and Tsg101/ALIX-dependent diversion of stress-internalized EGFR from the canonical endocytic pathway

scientific article published on 12 June 2015

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