Search filters

List of works by Ashley J. Hughes

A non-hemorrhagic hybrid heparin/heparan sulfate with anticoagulant potential.

scientific article

A zinc complex of heparan sulfate destabilises lysozyme and alters its conformation

scientific article published on 3 August 2012

Analysis of the fibroblast growth factor receptor (FGFR) signalling network with heparin as coreceptor: evidence for the expansion of the core FGFR signalling network.

scientific article published on 13 March 2013

Antithrombin stabilisation by sulfated carbohydrates correlates with anticoagulant activity

Assessing the Ability of Spectroscopic Methods to Determine the Difference in the Folding Propensities of Highly Similar β-Hairpins.

scientific article published on 13 February 2017

Chemically modified, non-anticoagulant heparin derivatives are potent galectin-3 binding inhibitors and inhibit circulating galectin-3-promoted metastasis.

scientific article

Detection of interaction between protein trytophan residues and small or macromolecular ligands by synchrotron radiation magnetic circular dichroism

scholarly article by Ashley J. Hughes et al published 2015 in Analytical Methods

Heparan sulfate and heparin interactions with proteins

scientific article

Heparan sulphate, its derivatives and analogues share structural characteristics that can be exploited, particularly in inhibiting microbial attachment.

scientific article published on 05 April 2012

Heparin derivatives for the targeting of multiple activities in the inflammatory response

scientific article published on 7 October 2014

Investigating the relationship between temperature, conformation and calcium binding in heparin model oligosaccharides.

scientific article

On the (un)coupling of the chromophore, tongue interactions, and overall conformation in a bacterial phytochrome

scientific article published in Journal of Biological Chemistry

Photoactivation of Drosophila melanogaster cryptochrome through sequential conformational transitions

scientific article published on 17 July 2019

Sequential conformational transitions and α-helical supercoiling regulate a sensor histidine kinase

scientific article published on 18 August 2017

Structural photoactivation of a full-length bacterial phytochrome

scientific article published on 12 August 2016

Time-Resolved X-Ray Solution Scattering Reveals the Structural Photoactivation of a Light-Oxygen-Voltage Photoreceptor

scientific article