List of works - Peter Meerlo

A brief period of sleep deprivation causes spine loss in the dentate gyrus of mice.

scientific article published on 24 March 2018

A social conflict increases EEG slow-wave activity during subsequent sleep

scientific article published in June 2001

A time for learning and a time for sleep: the effect of sleep deprivation on contextual fear conditioning at different times of the day.

scientific article published on October 2010

Acute social defeat does not alter cerebral 5-HT2A receptor binding in male Wistar rats

scientific article

Ageing-related decline in adenosine A1 receptor binding in the rat brain: an autoradiographic study

scientific article published in December 2004

Aggressive and sexual social stimuli do not phase shift the circadian temperature rhythm in rats

scientific article published on 01 May 1998

Alzheimer's disease pathogenesis: The role of disturbed sleep in attenuated brain plasticity and neurodegenerative processes

scientific article published on 16 September 2019

Animal studies on the role of sleep in memory: from behavioral performance to molecular mechanisms

scientific article

Basal metabolic rate in relation to body composition and daily energy expenditure in the field vole, Microtus agrestis

scientific article published in May 1997

Behavioural and physiological consequences of a single social defeat in Roman high- and low-avoidance rats

scientific article published in April 1997

Beta-endorphin modulates the acute response to a social conflict in male mice but does not play a role in stress-induced changes in sleep.

scientific article published in July 2003

Cardiac autonomic reactivity and salivary cortisol in men and women exposed to social stressors: relationship with individual ethological profile.

scientific article published in January 2003

Cerebral adenosine A₁ receptors are upregulated in rodent encephalitis

scientific article published on 7 February 2014

Changes in Behaviour and Body Weight Following a Single or Double Social Defeat in Rats

scientific article published in July 1996

Changes in daily rhythms of body temperature and activity after a single social defeat in rats

scientific article published in April 1996

Chronic Social Defeat Stress Shifts Peripheral Circadian Clocks in Male Mice in a Tissue-Specific and Time-of-Day Dependent Fashion

scientific article published in 2022

Chronic but not acute foot-shock stress leads to temporary suppression of cell proliferation in rat hippocampus.

scientific article published on 29 May 2009

Chronic partial sleep deprivation reduces brain sensitivity to glutamate N-methyl-D-aspartate receptor-mediated neurotoxicity

scientific article published on 14 June 2011

Chronic sleep restriction causes a decrease in hippocampal volume in adolescent rats, which is not explained by changes in glucocorticoid levels or neurogenesis

scientific article

Chronic stress and antidepressant treatment have opposite effects on P-glycoprotein at the blood-brain barrier: an experimental PET study in rats

scientific article published on 26 November 2009

Chronically restricted or disrupted sleep as a causal factor in the development of depression.

scientific article

Compartmentalized PDE4A5 Signaling Impairs Hippocampal Synaptic Plasticity and Long-Term Memory.

scientific article published on August 2016

Coping with sleep deprivation: shifts in regional brain activity and learning strategy.

scientific article published on November 2010

Daily acclimation handling does not affect hippocampal long-term potentiation or cause chronic sleep deprivation in mice

scientific article published on April 2013

Deep sleep after social stress: NREM sleep slow-wave activity is enhanced in both winners and losers of a conflict

scientific article published on 10 January 2015

Despite higher glucocorticoid levels and stress responses in female rats, both sexes exhibit similar stress-induced changes in hippocampal neurogenesis

scientific article

Differential effects of chronic partial sleep deprivation and stress on serotonin-1A and muscarinic acetylcholine receptor sensitivity

scientific article published in December 2006

Early maternal separation has mild effects on cardiac autonomic balance and heart structure in adult male rats

scientific article published on 21 December 2011

Early postnatal treatment with ACTH4-9 analog ORG 2766 improves adult spatial learning but does not affect behavioural stress reactivity

scientific article published in December 1999

Early-life origin of adult insomnia: does prenatal-early-life stress play a role?

scientific article published on 16 January 2015

Effects of active shock avoidance learning on hippocampal neurogenesis and plasma levels of corticosterone

scientific article published in February 2005

Effects of gamma-hydroxybutyrate (GHB) on vigilance states and EEG in mice

scientific article published in August 2004

Effects of sleep deprivation on cardiac autonomic and pituitary-adrenocortical stress reactivity in rats.

scientific article

Effects of social stimuli on sleep in mice: non-rapid-eye-movement (NREM) sleep is promoted by aggressive interaction but not by sexual interaction

scientific article

Elucidating the role of protein synthesis in hippocampus-dependent memory consolidation across the day and night

scientific article published on 21 January 2020

Enhanced hippocampal neurogenesis in the absence of microglia T cell interaction and microglia activation in the murine running wheel model

scientific article published on 01 August 2009

Exercise-induced promotion of hippocampal cell proliferation requires beta-endorphin.

scientific article published on 8 February 2008

Forced desynchrony of circadian rhythms of body temperature and activity in rats

scientific article

Hippocampal cell proliferation across the day: increase by running wheel activity, but no effect of sleep and wakefulness

scientific article published on 7 October 2005

Housing familiar male wildtype rats together reduces the long-term adverse behavioural and physiological effects of social defeat

scientific article published in April 1999

Human and rat gut microbiome composition is maintained following sleep restriction.

scientific article published on 8 February 2017

Increased food intake and changes in metabolic hormones in response to chronic sleep restriction alternated with short periods of sleep allowance

scientific article published on 19 October 2011

Increased maternal corticosterone levels in rats: effects on brain 5-HT1A receptors and behavioral coping with stress in adult offspring

scientific article

Individual differences in cardiovascular response to social challenge

scientific article

Intermittent exposure to social defeat and open-field test in rats: acute and long-term effects on ECG, body temperature and physical activity.

scientific article

Long-lasting consequences of a social conflict in rats: behavior during the interaction predicts subsequent changes in daily rhythms of heart rate, temperature, and activity

scientific article published in December 1999

Long-lasting pro-inflammatory suppression of microglia by LPS-preconditioning is mediated by RelB-dependent epigenetic silencing

scientific article published on 2 April 2015

Long-term changes in open field behaviour following a single social defeat in rats can be reversed by sleep deprivation

scientific article published in July 1996

Long-term effects of prenatal stress: changes in adult cardiovascular regulation and sensitivity to stress.

scientific article published on 13 August 2008

Maternal inflammation induces immune activation of fetal microglia and leads to disrupted microglia immune responses, behavior, and learning performance in adulthood

scientific article

Maternal separation decreases adult hippocampal cell proliferation and impairs cognitive performance but has little effect on stress sensitivity and anxiety in adult Wistar rats

scientific article published on 8 September 2010

Metabolic consequences of chronic sleep restriction in rats: changes in body weight regulation and energy expenditure.

scientific article published on 17 September 2012

Neonatal handling increases sensitivity to acute neurodegeneration in adult rats

scientific article

New neurons in the adult brain: the role of sleep and consequences of sleep loss

scientific article published on 09 October 2008

Novel Approach to Repeated Arterial Blood Sampling in Small Animal PET: Application in a Test-Retest Study with the Adenosine A1 Receptor Ligand [(11)C]MPDX.

scientific article

Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt

scientific article

P-glycoprotein Function in the Rodent Brain Displays a Daily Rhythm, a Quantitative In Vivo PET Study

scientific article

PET imaging of adenosine A1 receptor occupancy

scientific article published on 09 October 2014

Physical exercise leads to rapid adaptations in hippocampal vasculature: temporal dynamics and relationship to cell proliferation and neurogenesis

scientific article published in October 2009

Physiological and hormonal responses to novelty exposure in rats are mainly related to ongoing behavioral activity

scientific article

Plasma adiponectin is increased in mice selectively bred for high wheel-running activity, but not by wheel running per sé

scientific article published on 01 May 2007

Poor sleep as a potential causal factor in aggression and violence ⬇️

scientific article published on February 1, 2012

Postnatal treatment with ACTH-(4-9) analog ORG 2766 attenuates N-methyl-D-aspartate-induced excitotoxicity in rat nucleus basalis in adulthood.

scientific article

Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action.

scientific article published on January 2010

Remote long-term registrations of sleep-wake rhythms, core body temperature and activity in marmoset monkeys ⬇️

scientific article published on July 28, 2012

Repetitive stimulation of adenosine A1 receptors in vivo: changes in receptor numbers, G-proteins and A1 receptor agonist-induced hypothermia

scientific article published on 5 December 2007

Restraint increases prolactin and REM sleep in C57BL/6J mice but not in BALB/cJ mice

scientific article

Restricted and disrupted sleep: effects on autonomic function, neuroendocrine stress systems and stress responsivity.

scientific article published on 25 January 2008

Resveratrol preserves cerebrovascular density and cognitive function in aging mice.

scientific article

Sex differences in sleep: the response to sleep deprivation and restraint stress in mice

scientific article published in September 2006

Similar serotonin-2A receptor binding in rats with different coping styles or levels of aggression

scientific article

Sleep and adult neurogenesis: implications for cognition and mood

scientific article published on January 2015

Sleep deprivation and daily torpor impair object recognition in Djungarian hamsters

scientific article published on 25 October 2005

Sleep deprivation and hippocampal vulnerability: changes in neuronal plasticity, neurogenesis and cognitive function.

scientific article published on 29 April 2015

Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1.

scientific article published on 23 August 2016

Sleep deprivation impairs contextual fear conditioning and attenuates subsequent behavioural, endocrine and neuronal responses

scientific article published on 14 October 2010

Sleep deprivation impairs object recognition in mice

scientific article published on 19 January 2006

Sleep deprivation impairs spatial working memory and reduces hippocampal AMPA receptor phosphorylation.

scientific article published on 28 December 2009

Sleep restriction alters the hypothalamic-pituitary-adrenal response to stress.

scientific article published in May 2002

Sleep restriction by forced activity reduces hippocampal cell proliferation.

scientific article published on 23 November 2005

Sleep restriction in rats leads to changes in operant behaviour indicative of reduced prefrontal cortex function

scientific article published on 16 September 2016

Social stress in rats and mice.

scientific article published on January 1997

Social stress in rats: An animal model of depression?

scientific article published on 01 June 1995

Social stress induces high intensity sleep in rats

scientific article published in March 1997

Social stress models in rodents: Towards enhanced validity

scientific article published on 23 September 2016

Social stress, autonomic neural activation, and cardiac activity in rats.

scientific article

Stress revisited: a critical evaluation of the stress concept.

scientific article published on 21 February 2011

Stress, arousal, and sleep.

scientific article published on January 2015

Stress-induced changes in circadian rhythms of body temperature and activity in rats are not caused by pacemaker changes

scientific article published on 01 February 1997

TGFalpha and AVP in the mouse suprachiasmatic nucleus: anatomical relationship and daily profiles

scientific article published in August 2005

Telemetric Study of Sleep Architecture and Sleep Homeostasis in the Day-Active Tree Shrew Tupaia belangeri ⬇️

scientific article published on June 1, 2012

The European starling (Sturnus vulgaris) shows signs of NREM sleep homeostasis but has very little REM sleep and no REM sleep homeostasis

scientific article published on 21 December 2019

The continued need for animals to advance brain research

scientific article

The impact of stress and stress hormones on endogenous clocks and circadian rhythms

scientific article published in 2021

The influence of postnatal handling on adult neuroendocrine and behavioural stress reactivity

scientific article published on December 1999

The novel antidepressant agomelatine normalizes hippocampal neuronal activity and promotes neurogenesis in chronically stressed rats.

scientific article

The suprachiasmatic nucleus regulates sleep timing and amount in mice

scientific article

The temporal dynamics of the stress response.

scientific article published on November 1997

Too little sleep gradually desensitizes the serotonin 1A receptor system ⬇️

scientific article published in December 2005

Transiently increasing cAMP levels selectively in hippocampal excitatory neurons during sleep deprivation prevents memory deficits caused by sleep loss

scientific article

Use of 11C-MPDX and PET to study adenosine A1 receptor occupancy by nonradioactive agonists and antagonists.

scientific article published on 16 January 2014

List of works by Peter Meerlo

A brief period of sleep deprivation causes spine loss in the dentate gyrus of mice.

A social conflict increases EEG slow-wave activity during subsequent sleep

A time for learning and a time for sleep: the effect of sleep deprivation on contextual fear conditioning at different times of the day.

Acute social defeat does not alter cerebral 5-HT2A receptor binding in male Wistar rats

Ageing-related decline in adenosine A1 receptor binding in the rat brain: an autoradiographic study

Aggressive and sexual social stimuli do not phase shift the circadian temperature rhythm in rats

Alzheimer's disease pathogenesis: The role of disturbed sleep in attenuated brain plasticity and neurodegenerative processes

Animal studies on the role of sleep in memory: from behavioral performance to molecular mechanisms

Basal metabolic rate in relation to body composition and daily energy expenditure in the field vole, Microtus agrestis

Behavioural and physiological consequences of a single social defeat in Roman high- and low-avoidance rats

Beta-endorphin modulates the acute response to a social conflict in male mice but does not play a role in stress-induced changes in sleep.

Cardiac autonomic reactivity and salivary cortisol in men and women exposed to social stressors: relationship with individual ethological profile.

Cerebral adenosine A₁ receptors are upregulated in rodent encephalitis

Changes in Behaviour and Body Weight Following a Single or Double Social Defeat in Rats

Changes in daily rhythms of body temperature and activity after a single social defeat in rats

Chronic Social Defeat Stress Shifts Peripheral Circadian Clocks in Male Mice in a Tissue-Specific and Time-of-Day Dependent Fashion

Chronic but not acute foot-shock stress leads to temporary suppression of cell proliferation in rat hippocampus.

Chronic partial sleep deprivation reduces brain sensitivity to glutamate N-methyl-D-aspartate receptor-mediated neurotoxicity

Chronic sleep restriction causes a decrease in hippocampal volume in adolescent rats, which is not explained by changes in glucocorticoid levels or neurogenesis

Chronic stress and antidepressant treatment have opposite effects on P-glycoprotein at the blood-brain barrier: an experimental PET study in rats

Chronically restricted or disrupted sleep as a causal factor in the development of depression.

Compartmentalized PDE4A5 Signaling Impairs Hippocampal Synaptic Plasticity and Long-Term Memory.

Coping with sleep deprivation: shifts in regional brain activity and learning strategy.

Daily acclimation handling does not affect hippocampal long-term potentiation or cause chronic sleep deprivation in mice

Deep sleep after social stress: NREM sleep slow-wave activity is enhanced in both winners and losers of a conflict

Despite higher glucocorticoid levels and stress responses in female rats, both sexes exhibit similar stress-induced changes in hippocampal neurogenesis

Differential effects of chronic partial sleep deprivation and stress on serotonin-1A and muscarinic acetylcholine receptor sensitivity

Early maternal separation has mild effects on cardiac autonomic balance and heart structure in adult male rats

Early postnatal treatment with ACTH4-9 analog ORG 2766 improves adult spatial learning but does not affect behavioural stress reactivity

Early-life origin of adult insomnia: does prenatal-early-life stress play a role?

Effects of active shock avoidance learning on hippocampal neurogenesis and plasma levels of corticosterone

Effects of gamma-hydroxybutyrate (GHB) on vigilance states and EEG in mice

Effects of sleep deprivation on cardiac autonomic and pituitary-adrenocortical stress reactivity in rats.

Effects of social stimuli on sleep in mice: non-rapid-eye-movement (NREM) sleep is promoted by aggressive interaction but not by sexual interaction

Elucidating the role of protein synthesis in hippocampus-dependent memory consolidation across the day and night

Enhanced hippocampal neurogenesis in the absence of microglia T cell interaction and microglia activation in the murine running wheel model

Exercise-induced promotion of hippocampal cell proliferation requires beta-endorphin.

Forced desynchrony of circadian rhythms of body temperature and activity in rats

Hippocampal cell proliferation across the day: increase by running wheel activity, but no effect of sleep and wakefulness

Housing familiar male wildtype rats together reduces the long-term adverse behavioural and physiological effects of social defeat

Human and rat gut microbiome composition is maintained following sleep restriction.

Increased food intake and changes in metabolic hormones in response to chronic sleep restriction alternated with short periods of sleep allowance

Increased maternal corticosterone levels in rats: effects on brain 5-HT1A receptors and behavioral coping with stress in adult offspring

Individual differences in cardiovascular response to social challenge

Intermittent exposure to social defeat and open-field test in rats: acute and long-term effects on ECG, body temperature and physical activity.

Long-lasting consequences of a social conflict in rats: behavior during the interaction predicts subsequent changes in daily rhythms of heart rate, temperature, and activity

Long-lasting pro-inflammatory suppression of microglia by LPS-preconditioning is mediated by RelB-dependent epigenetic silencing

Long-term changes in open field behaviour following a single social defeat in rats can be reversed by sleep deprivation

Long-term effects of prenatal stress: changes in adult cardiovascular regulation and sensitivity to stress.

Maternal inflammation induces immune activation of fetal microglia and leads to disrupted microglia immune responses, behavior, and learning performance in adulthood

Maternal separation decreases adult hippocampal cell proliferation and impairs cognitive performance but has little effect on stress sensitivity and anxiety in adult Wistar rats

Metabolic consequences of chronic sleep restriction in rats: changes in body weight regulation and energy expenditure.

Neonatal handling increases sensitivity to acute neurodegeneration in adult rats

New neurons in the adult brain: the role of sleep and consequences of sleep loss

Novel Approach to Repeated Arterial Blood Sampling in Small Animal PET: Application in a Test-Retest Study with the Adenosine A1 Receptor Ligand [(11)C]MPDX.

Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt

P-glycoprotein Function in the Rodent Brain Displays a Daily Rhythm, a Quantitative In Vivo PET Study

PET imaging of adenosine A1 receptor occupancy

Physical exercise leads to rapid adaptations in hippocampal vasculature: temporal dynamics and relationship to cell proliferation and neurogenesis

Physiological and hormonal responses to novelty exposure in rats are mainly related to ongoing behavioral activity

Plasma adiponectin is increased in mice selectively bred for high wheel-running activity, but not by wheel running per sé

Poor sleep as a potential causal factor in aggression and violence ⬇️

Postnatal treatment with ACTH-(4-9) analog ORG 2766 attenuates N-methyl-D-aspartate-induced excitotoxicity in rat nucleus basalis in adulthood.

Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action.

Remote long-term registrations of sleep-wake rhythms, core body temperature and activity in marmoset monkeys ⬇️

Repetitive stimulation of adenosine A1 receptors in vivo: changes in receptor numbers, G-proteins and A1 receptor agonist-induced hypothermia

Restraint increases prolactin and REM sleep in C57BL/6J mice but not in BALB/cJ mice

Restricted and disrupted sleep: effects on autonomic function, neuroendocrine stress systems and stress responsivity.

Resveratrol preserves cerebrovascular density and cognitive function in aging mice.

Sex differences in sleep: the response to sleep deprivation and restraint stress in mice

Similar serotonin-2A receptor binding in rats with different coping styles or levels of aggression

Sleep and adult neurogenesis: implications for cognition and mood

Sleep deprivation and daily torpor impair object recognition in Djungarian hamsters

Sleep deprivation and hippocampal vulnerability: changes in neuronal plasticity, neurogenesis and cognitive function.

Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1.

Sleep deprivation impairs contextual fear conditioning and attenuates subsequent behavioural, endocrine and neuronal responses

Sleep deprivation impairs object recognition in mice

Sleep deprivation impairs spatial working memory and reduces hippocampal AMPA receptor phosphorylation.

Sleep restriction alters the hypothalamic-pituitary-adrenal response to stress.