List of works - Carrie L. Lucas

A CD8 T cell-intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo.

scientific article

Allospecific rejection of MHC class I-deficient bone marrow by CD8 T cells

scientific article

Antibodies against insulin measured by electrochemiluminescence predicts insulitis severity and disease onset in non-obese diabetic mice and can distinguish human type 1 diabetes status

scientific article published on 28 November 2011

Clinical and immunologic phenotype associated with activated phosphoinositide 3-kinase δ syndrome 2: A cohort study ⬇️

scientific article published on 21 April 2016

Conformational disruption of PI3Kδ regulation by immunodeficiency mutations in PIK3CD and PIK3R1.

scientific article published on 6 February 2017

Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency

scientific article

Effective "activated PI3Kδ syndrome"-targeted therapy with the PI3Kδ inhibitor leniolisib.

scientific article published on 29 September 2017

Expression and purification of soluble murine CD40L monomers and polymers in yeast Pichia pastoris.

scientific article

Genomics of Immune Diseases and New Therapies

scientific article published on 23 December 2015

Heterozygous splice mutation in PIK3R1 causes human immunodeficiency with lymphoproliferation due to dominant activation of PI3K

scientific article

Human PI3Kγ deficiency and its microbiota-dependent mouse model reveal immunodeficiency and tissue immunopathology

scientific article published on 25 September 2019

Human autoinflammatory disease reveals ELF4 as a transcriptional regulator of inflammation

scientific article published on 29 July 2021

Identifying genetic determinants of autoimmunity and immune dysregulation.

scientific article published on October 2015

Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D

scientific article

Novel PIK3CD mutations affecting N-terminal residues of p110δ cause activated PI3Kδ syndrome (APDS) in humans

scientific article published on 13 April 2017

Novel compound heterozygous variants in NHLRC2 in a patient with FINCA syndrome

scientific article published on 21 May 2020

PI3Kδ and primary immunodeficiencies.

scientific article published on 12 September 2016

Post-infectious inflammatory disease in MIS-C features elevated cytotoxicity signatures and autoreactivity that correlates with severity

scientific article published on 04 December 2020

Recipient dendritic cells, but not B cells, are required antigen-presenting cells for peripheral alloreactive CD8+ T-cell tolerance.

scientific article

List of works by Carrie L. Lucas

A CD8 T cell-intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo.

Allospecific rejection of MHC class I-deficient bone marrow by CD8 T cells

Antibodies against insulin measured by electrochemiluminescence predicts insulitis severity and disease onset in non-obese diabetic mice and can distinguish human type 1 diabetes status

Clinical and immunologic phenotype associated with activated phosphoinositide 3-kinase δ syndrome 2: A cohort study ⬇️

Conformational disruption of PI3Kδ regulation by immunodeficiency mutations in PIK3CD and PIK3R1.

Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency

Effective "activated PI3Kδ syndrome"-targeted therapy with the PI3Kδ inhibitor leniolisib.

Expression and purification of soluble murine CD40L monomers and polymers in yeast Pichia pastoris.

Genomics of Immune Diseases and New Therapies

Heterozygous splice mutation in PIK3R1 causes human immunodeficiency with lymphoproliferation due to dominant activation of PI3K

Human PI3Kγ deficiency and its microbiota-dependent mouse model reveal immunodeficiency and tissue immunopathology

Human autoinflammatory disease reveals ELF4 as a transcriptional regulator of inflammation

Identifying genetic determinants of autoimmunity and immune dysregulation.

Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D

Novel PIK3CD mutations affecting N-terminal residues of p110δ cause activated PI3Kδ syndrome (APDS) in humans

Novel compound heterozygous variants in NHLRC2 in a patient with FINCA syndrome

PI3Kδ and primary immunodeficiencies.

Post-infectious inflammatory disease in MIS-C features elevated cytotoxicity signatures and autoreactivity that correlates with severity

Recipient dendritic cells, but not B cells, are required antigen-presenting cells for peripheral alloreactive CD8+ T-cell tolerance.

SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?