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List of works by Jonathan R. Silva

A Molecularly Detailed NaV1.5 Model Reveals a New Class I Antiarrhythmic Target

scientific article published on 28 October 2019

A computationally efficient algorithm for fitting ion channel parameters.

scientific article published on 16 November 2016

A multiscale model linking ion-channel molecular dynamics and electrostatics to the cardiac action potential

scientific article

A novel NaV1.5 voltage sensor mutation associated with severe atrial and ventricular arrhythmias

scientific article published on 19 January 2016

Calmodulin acts as a state-dependent switch to control a cardiac potassium channel opening

scientific article published on 11 December 2020

Comments on "A model for human ventricular tissue"

scientific article published on 01 January 2005

Comments on: "Role of individual ionic current systems in ventricular cells hypothesized by a model study" by Matsuoka S, Sarai N, Kuratomi S, Ono K, and Noma A. Jpn J Physiol 53: 105-123, 2003

scientific article published on 01 October 2004

Computational biology in the study of cardiac ion channels and cell electrophysiology.

scientific article

Depolarization of the conductance-voltage relationship in the NaV1.5 mutant, E1784K, is due to altered fast inactivation.

scientific article published on 12 September 2017

Development of a Mixed Reality Platform for Lateral Skull Base Anatomy

scientific article published on 01 December 2018

Direct Measurement of Cardiac Na+ Channel Conformations Reveals Molecular Pathologies of Inherited Mutations.

scientific article published on 17 August 2015

Heterogeneity and function of K(ATP) channels in canine hearts.

scientific article published on 17 July 2013

How to Connect Cardiac Excitation to the Atomic Interactions of Ion Channels.

scientific article published in January 2018

Identification of structures for ion channel kinetic models

scientific article published on 16 August 2021

Ion Channel Associated Diseases: Overview of Molecular Mechanisms ⬇️

scientific article published on November 14, 2012

Kinetic properties of the cardiac L-type Ca2+ channel and its role in myocyte electrophysiology: a theoretical investigation.

scientific article published on 8 December 2006

Kv7.1 ion channels require a lipid to couple voltage sensing to pore opening.

scientific article published on 16 July 2013

Mechanism of pacemaking in I(K1)-downregulated myocytes.

scientific article published on February 2003

Mechanisms and models of cardiac sodium channel inactivation.

scientific article

Mechanisms of noncovalent β subunit regulation of NaV channel gating

scientific article published on 18 July 2017

Modeling K,ATP--dependent excitability in pancreatic islets.

scientific article

Modeling subunit cooperativity in opening of tetrameric ion channels.

scientific article published on 11 July 2008

Molecular motions that shape the cardiac action potential: Insights from voltage clamp fluorometry.

scientific article published on 24 December 2015

Multi-scale electrophysiology modeling: from atom to organ

scientific article

Predicting Patient Response to the Antiarrhythmic Mexiletine Based on Genetic Variation

scientific article published on 01 February 2019

Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium.

scientific article published on 23 January 2009

Regulation of Na+ channel inactivation by the DIII and DIV voltage-sensing domains.

scientific article published on 23 February 2017

Role of protein dynamics in ion selectivity and allosteric coupling in the NaK channel.

scientific article

Slow inactivation of Na(+) channels.

scientific article published on January 2014

Subunit interaction determines IKs participation in cardiac repolarization and repolarization reserve

scientific article published on 29 August 2005

The Xenopus oocyte cut-open vaseline gap voltage-clamp technique with fluorometry.

scientific article

Voltage-sensor movements describe slow inactivation of voltage-gated sodium channels I: Wild-type skeletal muscle NaV1.4 ⬇️

scientific article published on February 11, 2013

Voltage-sensor movements describe slow inactivation of voltage-gated sodium channels II: a periodic paralysis mutation in Na(V)1.4 (L689I)

scientific article published on 11 February 2013

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