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List of works by Thiago Mattar Cunha

-Chalcone Attenuates Pain and Inflammation in Experimental Acute Gout Arthritis in Mice

scientific article published on 02 October 2018

15d-PGJ-loaded nanocapsules ameliorate experimental gout arthritis by reducing pain and inflammation in a PPAR-gamma-sensitive manner in mice

scientific article published in Scientific Reports

15d-prostaglandin J2 inhibits inflammatory hypernociception: involvement of peripheral opioid receptor

scientific article

5-lipoxygenase deficiency reduces acetaminophen-induced hepatotoxicity and lethality

scientific article published on 31 October 2013

9The PI3Kγ/AKT signaling pathway mediates peripheral antinociceptive action of dipyrone

scientific article published on 26 September 2020

A Short Peptide That Mimics the Binding Domain of TGF-β1 Presents Potent Anti-Inflammatory Activity

scientific article published on 27 August 2015

Ablation of sensory nerves favours melanoma progression

scientific article published on 20 July 2020

Access to health care as a human right in international policy: critical reflections and contemporary challenges

scientific article published in July 2017

Acetic acid- and phenyl-p-benzoquinone-induced overt pain-like behavior depends on spinal activation of MAP kinases, PI(3)K and microglia in mice.

scientific article published on 28 January 2012

Activation of PPAR-γ induces macrophage polarization and reduces neutrophil migration mediated by heme oxygenase 1

scientific article published on 06 May 2020

Agglutinin isolated from the red marine alga Hypnea cervicornis J. Agardh reduces inflammatory hypernociception: involvement of nitric oxide

scientific article published on 30 June 2010

Analgesic and side effects of intravenous recombinant Phα1β

scientific article published on 17 April 2020

Anti-inflammatory and Anti-nociceptive Activity of Ruthenium Complexes with Isonicotinic and Nicotinic Acids (Niacin) as Ligands.

scientific article

Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: Inhibition of cytokine production-dependent mechanism

scientific article published on 01 February 2007

Anti-inflammatory and anti-Candida Effects of Brazilian Organic Propolis, a Promising Source of Bioactive Molecules and Functional Food

scientific article published on 23 August 2019

Anti-inflammatory and anti-biofilm properties of ent -nemorosone from Brazilian geopropolis

article

Antigen-induced inflammatory mechanical hypernociception in mice is mediated by IL-18.

scientific article published on 27 December 2006

Antinociceptive effects of HUF-101, a fluorinated cannabidiol derivative

scientific article

Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state.

scientific article published on 04 October 2016

Aqueous extracts from Uncaria tomentosa (Willd. ex Schult.) DC. reduce bronchial hyperresponsiveness and inflammation in a murine model of asthma

scientific article published on 9 February 2018

Baroreflex activation in conscious rats modulates the joint inflammatory response via sympathetic function.

scientific article

Bioactive Fraction of Geopropolis from Melipona scutellaris Decreases Neutrophils Migration in the Inflammatory Process: Involvement of Nitric Oxide Pathway.

scientific article published on 30 April 2013

Blockade of Bradykinin Receptors or Angiotensin II Type 2 Receptor Prevents Paclitaxel-Associated Acute Pain Syndrome in Mice

scientific article published on 23 September 2020

Bosentan, a mixed endothelin receptor antagonist, inhibits superoxide anion-induced pain and inflammation in mice

scientific article

Bosentan, an endothelin receptor antagonist, ameliorates collagen-induced arthritis: the role of TNF-α in the induction of endothelin system genes

scientific article

Budlein A, a Sesquiterpene Lactone From , Alleviates Pain and Inflammation in a Model of Acute Gout Arthritis in Mice

scholarly article by Victor Fattori et al published 2018 in Frontiers in Pharmacology

C5a and pain development: An old molecule, a new target.

scientific article published on 5 February 2016

CCR2 Expression in Neutrophils Plays a Critical Role in Their Migration Into the Joints in Rheumatoid Arthritis.

scientific article published in July 2015

CCR5-Positive Inflammatory Monocytes are Crucial for Control of Sepsis

scientific article published on 01 November 2019

CD163 overexpression using a macrophage-directed gene therapy approach improves wound healing in ex vivo and in vivo human skin models

scientific article published on 04 November 2019

CXCL1/CXCR2 signaling in pathological pain: Role in peripheral and central sensitization

scientific article published on 3 June 2017

Cannabidiol prevents haloperidol-induced vacuos chewing movements and inflammatory changes in mice via PPARγ receptors

scientific article published on 11 September 2018

Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis

scientific article published on 17 April 2018

Carotid sinus nerve electrical stimulation in conscious rats attenuates systemic inflammation via chemoreceptor activation

scientific article published on 24 July 2017

Caspase-1 is involved in the genesis of inflammatory hypernociception by contributing to peripheral IL-1β maturation

scientific article published on 4 October 2010

Choline attenuates inflammatory hyperalgesia activating nitric oxide/cGMP/ATP-sensitive potassium channels pathway

scientific article published on 26 November 2019

Chronic ethanol consumption reduces adrenomedullin-induced relaxation in the isolated rat aorta.

scientific article

Chronic restraint stress increases angiotensin II potency in the rat carotid: role of cyclooxygenases and reactive oxygen species

scientific article published on 24 October 2016

Cigarette smoke induces miR-132 in Th17 cells that enhance osteoclastogenesis in inflammatory arthritis

scholarly article

Cinnamoyloxy-mammeisin Isolated from Geopropolis Attenuates Inflammatory Process by Inhibiting Cytokine Production: Involvement of MAPK, AP-1, and NF-κB.

scientific article published in July 2016

Colitis generates remote antinociception in rats: the role of the L-arginine/NO/cGMP/PKG/KATP pathway and involvement of cannabinoid and opioid systems.

scientific article

Collagen induced arthritis (CIA) in mice features regulatory transcriptional network connecting major histocompatibility complex (MHC H2) with autoantigen genes in the thymus

article

Combination of Mass Cytometry and Imaging Analysis Reveals Origin, Location, and Functional Repopulation of Liver Myeloid Cells in Mice.

scientific article

Commercial sunscreen formulations: UVB irradiation stability and effect on UVB irradiation-induced skin oxidative stress and inflammation

scientific article published on 5 September 2016

Contribution of spinal cord glial cells to L. amazonensis experimental infection-induced pain in BALB/c mice

scientific article published on 28 May 2019

Correction: T Cell Post-Transcriptional miRNA-mRNA Interaction Networks Identify Targets Associated with Susceptibility/Resistance to Collagen-induced Arthritis.

correction of a scientific article

Cortical stimulation in conscious rats controls joint inflammation

scientific article published on 6 March 2018

Crucial role of neutrophils in the development of mechanical inflammatory hypernociception

scientific article

Curcumin inhibits superoxide anion-induced pain-like behavior and leukocyte recruitment by increasing Nrf2 expression and reducing NF-κB activation

scientific article

DF2755A, a novel non-competitive allosteric inhibitor of CXCR1/2, reduces inflammatory and post-operative pain

scientific article published on 16 November 2015

DMH-CBD, a cannabidiol analog with reduced cytotoxicity, inhibits TNF production by targeting NF-kB activity dependent on A2A receptor

scientific article published on 20 February 2019

Differential regulation of oxidative stress and cytokine production by endothelin ETA and ETB receptors in superoxide anion-induced inflammation and pain in mice

scientific article published on 24 October 2016

Diosmin reduces chronic constriction injury-induced neuropathic pain in mice

scientific article published on 15 June 2017

Direct blockade of inflammatory hypernociception by peripheral A1 adenosine receptors: involvement of the NO/cGMP/PKG/KATP signaling pathway

scientific article published on September 2010

Doxycycline Suppresses Microglial Activation by Inhibiting the p38 MAPK and NF-kB Signaling Pathways

scientific article

Dual role of hydrogen sulfide in mechanical inflammatory hypernociception

scientific article published on 7 June 2008

Dynamic weight bearing is an efficient and predictable method for evaluation of arthritic nociception and its pathophysiological mechanisms in mice

scientific article

Efferocytosis of SARS-CoV-2-infected dying cells impairs macrophage anti-inflammatory functions and clearance of apoptotic cells

scientific article published on 6 June 2022

Endothelin-1 induces neutrophil recruitment in adaptive inflammation via TNFα and CXCL1/CXCR2 in mice

scientific article published on 09 February 2012

Enhancing untargeted metabolomics using metadata-based source annotation

scientific article published in 2022

Erratum to: The Sesquiterpene Lactone, Budlein A, Inhibits Antigen-Induced Arthritis in Mice: Role of NF-κB and Cytokines

scientific article published on 6 September 2017

Erratum to: The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia

scholarly article published in Naunyn-Schmiedeberg's Archives of Pharmacology

Essential roles of PKA, iNOS, CD95/CD95L, and terminal caspases in suppression of eosinopoiesis by PGE2 and other cAMP-elevating agents

Estudo da atividade de uma 4-fenil cumarina na diferenciação de linfócitos Th17 no desenvolvimento da doença periodontal

Ethanol consumption alters the expression and reactivity of adrenomedullin in the rat mesenteric arterial bed.

scientific article

Experimental Model of Rectal Carcinogenesis Induced by N-Methyl-N-Nitrosoguanidine in Mice with Endoscopic Evaluation

scientific article published on 10 September 2020

Experimental chemotherapy in paracoccidioidomycosis using ruthenium NO donor

scientific article

Flavonoids as Anti-Inflammatory and Analgesic Drugs: Mechanisms of Action and Perspectives in the Development of Pharmaceutical Forms

article

Fractalkine mediates inflammatory pain through activation of satellite glial cells ⬇️

scientific article published on June 17, 2013

From environmental ethics to environmental bioethics: antecedents, trajectories, and perspectives

scientific article published in April 2017

Frontline Science: Blood-circulating leukocytes fail to infiltrate the spinal cord parenchyma after spared nerve injury

scientific article published on 31 May 2019

Fructose 1,6-bisphosphate, a high-energy intermediate of glycolysis, attenuates experimental arthritis by activating anti-inflammatory adenosinergic pathway

scientific article

Gastro-protective effects of isobrucein B, a quassinoid isolated from Picrolemma sprucei

scientific article published in March 2014

Geopropolis from Melipona scutellaris decreases the mechanical inflammatory hypernociception by inhibiting the production of IL-1β and TNF-α.

scientific article published on 4 August 2012

Glial modulation of pain: a step beyond

scientific article published on March 2009

Granulocyte-Colony Stimulating Factor (G-CSF) induces mechanical hyperalgesia via spinal activation of MAP kinases and PI3K in mice

scientific article published on 12 January 2011

Granulocyte-colony stimulating factor (G-CSF)-induced mechanical hyperalgesia in mice: Role for peripheral TNFα, IL-1β and IL-10

scientific article published on 10 January 2015

Hesperidin Methylchalcone Suppresses Experimental Gout Arthritis in Mice by Inhibiting NF-κB Activation

scientific article published on 13 June 2018

Hydrogen sulfide augments neutrophil migration through enhancement of adhesion molecule expression and prevention of CXCR2 internalization: role of ATP-sensitive potassium channels

scientific article published in September 2008

Hydrogen sulfide, is it a promise analgesic drug or another inflammatory pain mediator?

scientific article published on 05 June 2007

Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells

scientific article published on 22 January 2020

Hyperbaric oxygen therapy ameliorates TNBS-induced acute distal colitis in rats.

scientific article published on 16 April 2015

Hypernociception elicited by tibio-tarsal joint flexion in mice: a novel experimental arthritis model for pharmacological screening

scientific article published on 21 June 2006

Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development?

scientific article

IL-15 mediates antigen-induced neutrophil migration by triggering IL-18 production

scientific article published in December 2007

IL-15 mediates immune inflammatory hypernociception by triggering a sequential release of IFN-gamma, endothelin, and prostaglandin

scholarly article

IL-17 mediates articular hypernociception in antigen-induced arthritis in mice

scientific article published on 6 December 2009

IL-27 Counteracts Neuropathic Pain Development Through Induction of IL-10

scientific article published on 01 January 2019

IL-33 enhances macrophage release of IL-1β and promotes pain and inflammation in gouty arthritis

scientific article published on 04 September 2020

IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy

scientific article published on 14 May 2010

IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice

scholarly article

In vitro and in vivo photoprotective/photochemopreventive potential of Garcinia brasiliensis epicarp extract

scientific article published on 17 January 2014

Indoleamine-2,3-Dioxygenase/Kynurenine Pathway as a Potential Pharmacological Target to Treat Depression Associated with Diabetes.

scientific article published on 15 December 2015

Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients

scientific article published on 01 March 2021

Inhibition of 5-lipoxygenase alleviates graft-versus-host disease.

scientific article

Inhibition of peripheral anion exchanger 3 decreases formalin-induced pain

scientific article published on 27 May 2014

Inhibition of spinal p38 MAPK prevents articular neutrophil infiltration in experimental arthritis via sympathetic activation.

scientific article published on 5 December 2017

Interleukin-10 limits intense acute swimming-induced muscle mechanical hyperalgesia in mice

scientific article

Interleukin-18 induces mechanical hypernociception in rats via endothelin acting on ETB receptors in a morphine-sensitive manner

scientific article published on 29 March 2004

Interleukin-33 Receptor (ST2) Deficiency Improves the Outcome of Staphylococcus aureus-Induced Septic Arthritis.

scientific article

Involvement of LTB4 in zymosan-induced joint nociception in mice: participation of neutrophils and PGE2.

scientific article published on 3 October 2007

Involvement of nuclear factor kappa B in the maintenance of persistent inflammatory hypernociception.

scientific article

Involvement of the Hsp70/TLR4/IL-6 and TNF-α pathways in delayed-onset muscle soreness

scientific article published on 16 March 2020

Joint NOD2/RIPK2 signaling regulates IL-17 axis and contributes to the development of experimental arthritis

scientific article

Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production

scientific article

Kaurenoic acid from Sphagneticola trilobata Inhibits Inflammatory Pain: effect on cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway.

scientific article published on 10 May 2012

Kinins and their B1 and B2 receptors are involved in fibromyalgia-like pain symptoms in mice

scientific article published on 26 June 2019

Lapachol, a compound targeting pyrimidine metabolism, ameliorates experimental autoimmune arthritis

scientific article published on 7 March 2017

Lipopolysaccharide induces inflammatory hyperalgesia triggering a TLR4/MyD88-dependent cytokine cascade in the mice paw

scientific article

Lipoxin A4 impairs effective bacterial control and potentiates joint inflammation and damage caused by Staphylococcus aureus infection

scientific article published on 02 August 2020

Liver Immune Cells Release Type 1 Interferon Due to DNA Sensing and Amplify Liver Injury from Acetaminophen Overdose

scientific article published on 27 July 2018

Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis

scientific article

MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression

scientific article published on 03 August 2020

Main pathways of action of Brazilian red propolis on the modulation of neutrophils migration in the inflammatory process.

scientific article published on 28 September 2016

Mechanisms Underlying the Scratching Behavior Induced by the Activation of Proteinase-Activated Receptor-4 in Mice.

scientific article published on 8 May 2015

Mechanisms underlying the hyperalgesic responses triggered by joint activation of TLR4.

scientific article published on 24 August 2016

Medial plantar nerve ligation as a novel model of neuropathic pain in mice: pharmacological and molecular characterization

scientific article published on 27 May 2016

Meniscal transection rather than excision increases pain behavior and structural damage in experimental osteoarthritis in mice

scientific article published on 31 July 2014

Methyl gallate attenuates inflammation induced by Toll-like receptor ligands by inhibiting MAPK and NF-Κb signaling pathways

scientific article published on 09 October 2020

Modulation of experimental arthritis by vagal sensory and central brain stimulation.

scientific article published on 6 April 2017

Molecular basis of carrageenan-induced cytokines production in macrophages

scientific article published on 07 September 2020

Monosodium urate crystal interleukin-1β release is dependent on Toll-like receptor 4 and transient receptor potential V1 activation

scientific article published on 01 January 2020

Monosodium urate crystal interleukin-1β release is dependent on Toll-like receptor 4 and transient receptor potential V1 activation

scientific article published in January 2020

Morphine peripheral analgesia depends on activation of the PI3Kgamma/AKT/nNOS/NO/KATP signaling pathway

scientific article

NDP-MSH inhibits neutrophil migration through nicotinic and adrenergic receptors in experimental peritonitis

scientific article published on 22 January 2013

NLRP12 controls arthritis severity by acting as a checkpoint inhibitor of Th17 cell differentiation

scientific article published on 07 July 2020

NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B4 in a murine model of gout

article

NOD2-RIP2-Mediated Signaling Helps Shape Adaptive Immunity in Visceral Leishmaniasis.

scientific article

NOSH-aspirin (NBS-1120), a dual nitric oxide and hydrogen sulfide-releasing hybrid, reduces inflammatory pain

scientific article published on 8 May 2015

Naringenin mitigates titanium dioxide (TiO)-induced chronic arthritis in mice: role of oxidative stress, cytokines, and NFκB

scholarly article by Marília F Manchope et al published 28 October 2018 in Inflammation Research

Naringenin mitigates titanium dioxide (TiO2)-induced chronic arthritis in mice: role of oxidative stress, cytokines, and NFκB

scholarly article by Marília F. Manchope et al published 28 October 2018 in Inflammation Research

Neovestitol, an isoflavonoid isolated from Brazilian red propolis, reduces acute and chronic inflammation: involvement of nitric oxide and IL-6.

scientific article published on 7 November 2016

Neuroimmune-Glia Interactions in the Sensory Ganglia Account for the Development of Acute Herpetic Neuralgia

scientific article published on 2 June 2017

Neurological and Inflammatory Manifestations in Sjögren's Syndrome: The Role of the Kynurenine Metabolic Pathway

article published in 2018

Neutrophil Recruitment and Articular Hyperalgesia in Antigen-Induced Arthritis are Modulated by the Cholinergic Anti-Inflammatory Pathway

scientific article

Neutrophil extracellular traps mediate joint hyperalgesia induced by immune inflammation

scientific article published on 26 December 2020

Neutrophils: are they hyperalgesic or anti-hyperalgesic?

scientific article published on 07 August 2006

Nitroxyl inhibits overt pain-like behavior in mice: role of cGMP/PKG/ATP-sensitive potassium channel signaling pathway

scientific article

Nociceptive effect of subcutaneously injected interleukin-12 is mediated by endothelin (ET) acting on ETB receptors in rats

scientific journal article

Non-Peptidergic Nociceptive Neurons Are Essential for Mechanical Inflammatory Hypersensitivity in Mice

scientific article published on 23 January 2019

Nucleosides from Phlebotomus papatasi salivary gland ameliorate murine collagen-induced arthritis by impairing dendritic cell functions.

scientific article

Optimization of timing of insemination of dairy heifers inseminated with sex-sorted semen

scientific article published on 03 April 2020

PKM2 promotes Th17 cell differentiation and autoimmune inflammation by fine-tuning STAT3 activation

scientific article published on 01 October 2020

Paclitaxel Reduces Tumor Growth by Reprogramming Tumor-Associated Macrophages to an M1 Profile in a TLR4-Dependent Manner

scientific article published on 13 August 2018

Participation of transient receptor potential vanilloid 1 in paclitaxel-induced acute visceral and peripheral nociception in rodents

scientific article published on 22 March 2018

Pericytes modulate myelination in the central nervous system

scientific article published on 7 December 2017

Peripheral NLCR4 inflammasome participates in the genesis of acute inflammatory pain

scientific article published on 01 March 2015

Peripheral nitric oxide signaling directly blocks inflammatory pain

scientific article published on 18 February 2020

Pharmacological Beta-Adrenergic Receptor Activation Attenuates Neutrophil Recruitment by a Mechanism Dependent on Nicotinic Receptor and the Spleen

scientific article

Phlebotomine salivas inhibit immune inflammation-induced neutrophil migration via an autocrine DC-derived PGE2/IL-10 sequential pathway

scientific article

Poligalen, a new coumarin from Polygala boliviensis, reduces the release of TNF and IL-6 independent of NF-kB downregulation

scientific article published on 2 August 2016

Polymorphism in the catalytic subunit of the PI3Kγ gene is associated with Trypanosoma cruzi-induced chronic chagasic cardiomyopathy

scientific article published on 07 December 2020

Probucol attenuates lipopolysaccharide-induced leukocyte recruitment and inflammatory hyperalgesia: effect on NF-кB activation and cytokine production

scientific article published on 10 May 2017

Probucol attenuates overt pain-like behavior and carrageenan-induced inflammatory hyperalgesia and leukocyte recruitment by inhibiting NF-кB activation and cytokine production without antioxidant effects

scientific article published on 6 April 2017

Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production

scientific journal article

Protective effect of an extract from Ascaris suum in experimental arthritis models

scientific article published on 14 April 2008

Pyrrolidine dithiocarbamate inhibits UVB-induced skin inflammation and oxidative stress in hairless mice and exhibits antioxidant activity in vitro.

scientific article

Pyrrolidine dithiocarbamate inhibits superoxide anion-induced pain and inflammation in the paw skin and spinal cord by targeting NF-κB and oxidative stress

scientific article published on 09 May 2016

Quercetin Reduces Neutrophil Recruitment Induced by CXCL8, LTB4, and fMLP: Inhibition of Actin Polymerization

scientific article published on 28 January 2011

Quercetin reduces inflammatory pain: inhibition of oxidative stress and cytokine production

scientific article published in November 2009

Regulatory T cells counteract neuropathic pain through inhibition of the Th1 response at the site of peripheral nerve injury

scientific article published on 26 March 2020

Relative expression of KLK5 to LEKTI is associated with aggressiveness of oral squamous cell carcinoma

scientific article published on 28 November 2020

Repurposing of the Nootropic Drug Vinpocetine as an Analgesic and Anti-Inflammatory Agent: Evidence in a Mouse Model of Superoxide Anion-Triggered Inflammation

scientific article published on 31 March 2019

Role of IL-18 in overt pain-like behaviour in mice

scientific article published on 9 April 2008

Role of TNF-α/TNFR1 in intense acute swimming-induced delayed onset muscle soreness in mice

scientific article published on 08 February 2014

Role of cytokines in mediating mechanical hypernociception in a model of delayed-type hypersensitivity in mice

scientific article published on 26 March 2008

S100A9 plays a pivotal role in a mouse model of herpetic neuralgia via TLR4/TNF pathway

scientific article published on 31 March 2020

SARS-CoV-2 triggered neutrophil extracellular traps (NETs) mediate COVID-19 pathology

scientific article published on 9 June 2020

SARS-CoV-2 uses CD4 to infect T helper lymphocytes

scientific article published on 31 July 2023

SARS-CoV-2-triggered neutrophil extracellular traps mediate COVID-19 pathology

scientific article published on 01 December 2020

SN-38, the active metabolite of irinotecan, inhibits the acute inflammatory response by targeting toll-like receptor 4

scientific article published on 22 April 2019

Sensory Ganglia-Specific TNF Expression Is Associated With Persistent Nociception After Resolution of Inflammation

scientific article published on 01 January 2019

Sensory nerves in the spotlight of the stem cell niche

scientific article published on 28 October 2020

Skin vasodilation and analgesic effect of a topical nitric oxide-releasing hydrogel

scientific article published on 12 June 2013

Spinal GABA-B receptor modulates neutrophil recruitment to the knee joint in zymosan-induced arthritis

scientific article published on 23 April 2016

Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain

scientific article published on 26 August 2015

Stimulation of peripheral kappa opioid receptors inhibits inflammatory hyperalgesia via activation of the PI3Kγ/AKT/nNOS/NO signaling pathway

scientific article published on 8 February 2012

Succinate causes pathological cardiomyocyte hypertrophy through GPR91 activation.

scientific article

Succinate receptor deficiency attenuates arthritis by reducing dendritic cell traffic and expansion of Th17 cells in the lymph nodes

scientific article published on 12 June 2018

Superoxide anion-induced pain and inflammation depends on TNFα/TNFR1 signaling in mice

scientific article published on 18 August 2015

Synthetic chalcones as potential tool for acute- and chronic-pain control

scientific article published on 25 May 2018

Systemic lupus erythematosus onset in lupus-prone B6.MRL/lpr mice Is influenced by weight gain and Is preceded by an increase in neutrophil oxidative burst activity.

scientific article published on 24 June 2015

T cell post-transcriptional miRNA-mRNA interaction networks identify targets associated with susceptibility/resistance to collagen-induced arthritis

scientific article (publication date: 2013)

TGF-β signalling defect is linked to low CD39 expression on regulatory T cells and methotrexate resistance in rheumatoid arthritis.

scientific article published on 6 February 2018

TNF-α and IL-1β mediate inflammatory hypernociception in mice triggered by B1 but not B2 kinin receptor

scientific article published on 13 July 2007

TRPV1 Contributes to Cerebral Malaria Severity and Mortality by Regulating Brain Inflammation

scientific article published on 16 May 2019

Targeting IL-33/ST2 signaling: regulation of immune function and analgesia

scientific article

Targeting endothelin ETA and ETB receptors inhibits antigen-induced neutrophil migration and mechanical hypernociception in mice

scientific article

Targeting interleukin-1β reduces intense acute swimming-induced muscle mechanical hyperalgesia in mice.

scientific article

Targeting nitric oxide as a key modulator of sepsis, arthritis and pain

scientific article published on 30 April 2019

Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief

scientific article

The Adaptor Protein Myd88 Is a Key Signaling Molecule in the Pathogenesis of Irinotecan-Induced Intestinal Mucositis

scientific article

The Atypical Chemokine Receptor ACKR2 is Protective Against Sepsis

scientific article published on 24 August 2017

The NLRP3 inflammasome is involved with the pathogenesis of Mayaro virus

scientific article published on 03 September 2019

The NOD2 signaling in peripheral macrophages contributes to neuropathic pain development

scientific article published on 01 January 2019

The Sesquiterpene Lactone, Budlein A, Inhibits Antigen-Induced Arthritis in Mice: Role of NF-κB and Cytokines

scientific article published on 01 December 2017

The citrus flavanone naringenin reduces gout-induced joint pain and inflammation in mice by inhibiting the activation of NFκB and macrophage release of IL-1β

The citrus flavonone naringenin reduces lipopolysaccharide-induced inflammatory pain and leukocyte recruitment by inhibiting NF-κB activation

scientific article published in April 2016

The nitroxyl donor, Angeli's salt, inhibits inflammatory hyperalgesia in rats

scientific article published on 27 March 2013

The nitroxyl donor, Angeli's salt, reduces chronic constriction injury-induced neuropathic pain

scientific article published on 7 June 2016

The quassinoid isobrucein B reduces inflammatory hyperalgesia and cytokine production by post-transcriptional modulation.

scientific article published on 10 February 2015

The role of 5-lipoxygenase in Aggregatibacter actinomycetemcomitans-induced alveolar bone loss.

scientific article published in June 2017

The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia

scientific article published on 28 November 2012

The role of neutrophils in neuro-immune modulation

scientific article published on 28 November 2019

Therapeutic Treatment of Arthritic Mice with 15-Deoxy Δ12,14-Prostaglandin J2 (15d-PGJ2) Ameliorates Disease through the Suppression of Th17 Cells and the Induction of CD4+CD25-FOXP3+ Cells.

scientific article published on 31 October 2016

Thirty days after anterior cruciate ligament transection is sufficient to induce signs of knee osteoarthritis in rats: pain, functional impairment, and synovial inflammation

scientific article published on 31 January 2020

Toll-like receptor 2/MyD88 signaling mediates zymosan-induced joint hypernociception in mice: Participation of TNF-α, IL-1β and CXCL1/KC

scientific article published on 25 October 2011

Toll-like receptor 9 activation in neutrophils impairs chemotaxis and reduces sepsis outcome

scientific article published in September 2012

Transient receptor potential ankyrin 1 (TRPA1) plays a critical role in a mouse model of cancer pain

article

Trypanosoma cruzi adjuvants potentiate T cell-mediated immunity induced by a NY-ESO-1 based antitumor vaccine

scientific article

Ts8 scorpion toxin inhibits the Kv4.2 channel and produces nociception in vivo

scientific article published on 23 June 2016

Tumor necrosis factor-α receptor 1 contributes to ethanol-induced vascular reactive oxygen species generation and hypertension.

scientific article

Using an experimental model for the study of therapeutic touch

scientific article published on 01 February 2013

Vagus nerve regulates the phagocytic and secretory activity of resident macrophages in the liver

scientific article published on 02 July 2019

Vestitol Isolated from Brazilian Red Propolis Inhibits Neutrophils Migration in the Inflammatory Process: Elucidation of the Mechanism of Action

scientific article published on 3 March 2016

Vinpocetine reduces lipopolysaccharide-induced inflammatory pain and neutrophil recruitment in mice by targeting oxidative stress, cytokines and NF-κB.

scientific article published on 14 May 2015

Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase

scientific article

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