List of works - Michael P Smith

A PAX3/BRN2 rheostat controls the dynamics of BRAF mediated MITF regulation in MITF /AXL melanoma

scientific article published on 19 October 2018

An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition

scientific article

Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma

scientific article published on 28 April 2017

Collagen abundance controls melanoma phenotypes through lineage-specific microenvironment sensing.

scientific article published on 16 March 2018

Differentiation of THP1 Cells into Macrophages for Transwell Co-culture Assay with Melanoma Cells.

scientific article published on May 2015

Discovery of a Gatekeeper Residue in the C-Terminal Tail of the Extracellular Signal-Regulated Protein Kinase 5 (ERK5)

scientific article published on 31 January 2020

Effect of SMURF2 targeting on susceptibility to MEK inhibitors in melanoma

scientific article published on 17 December 2012

Enhanced Fatty Acid Scavenging and Glycerophospholipid Metabolism Accompany Melanocyte Neoplasia Progression in Zebrafish

scientific article published on 12 March 2019

Glucose availability controls ATF4-mediated MITF suppression to drive melanoma cell growth.

scientific article published on 23 March 2017

Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy

scientific article published on March 2016

MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide

scientific article

Molecular Pathways: Maintaining MAPK Inhibitor Sensitivity by Targeting Nonmutational Tolerance.

scientific article published on 19 October 2016

Osteoblasts contribute to a protective niche that supports melanoma cell proliferation and survival

scientific article published on 08 August 2019

Reciprocal priming between receptor tyrosine kinases at recycling endosomes orchestrates cellular signalling outputs

scientific article published on 04 June 2021

Targeting MITF in the tolerance-phase

scientific article published on 18 May 2016

Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure

scientific article published on 12 June 2017

The immune microenvironment confers resistance to MAPK pathway inhibitors through macrophage-derived TNFα

scientific article

List of works by Michael P Smith

A PAX3/BRN2 rheostat controls the dynamics of BRAF mediated MITF regulation in MITF /AXL melanoma

An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition

Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma

Collagen abundance controls melanoma phenotypes through lineage-specific microenvironment sensing.

Differentiation of THP1 Cells into Macrophages for Transwell Co-culture Assay with Melanoma Cells.

Discovery of a Gatekeeper Residue in the C-Terminal Tail of the Extracellular Signal-Regulated Protein Kinase 5 (ERK5)

Effect of SMURF2 targeting on susceptibility to MEK inhibitors in melanoma

Enhanced Fatty Acid Scavenging and Glycerophospholipid Metabolism Accompany Melanocyte Neoplasia Progression in Zebrafish

Glucose availability controls ATF4-mediated MITF suppression to drive melanoma cell growth.

Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy

MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide

Molecular Pathways: Maintaining MAPK Inhibitor Sensitivity by Targeting Nonmutational Tolerance.

Osteoblasts contribute to a protective niche that supports melanoma cell proliferation and survival

Reciprocal priming between receptor tyrosine kinases at recycling endosomes orchestrates cellular signalling outputs

Targeting MITF in the tolerance-phase

Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure

The immune microenvironment confers resistance to MAPK pathway inhibitors through macrophage-derived TNFα