List of works - Gary W Jones

(-)-epigallocatechin-3-gallate inhibits fibrillogenesis of chicken cystatin.

scientific article published on 3 February 2015

A proteomic approach to investigating gene cluster expression and secondary metabolite functionality in Aspergillus fumigatus

scientific article

A role for cytosolic hsp70 in yeast [PSI(+)] prion propagation and [PSI(+)] as a cellular stress.

scientific article

Alcohol oxidase (AOX1) from Pichia pastoris is a novel inhibitor of prion propagation and a potential ATPase.

scientific article published on 11 December 2008

Aspergillus fumigatus protein phosphatase PpzA is involved in iron assimilation, secondary metabolite production, and virulence

scientific article

Assessment of inactivating stop codon mutations in forty Saccharomyces cerevisiae strains: implications for [PSI] prion- mediated phenotypes

scientific article

CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression

scientific article

Chaperoning prions: the cellular machinery for propagating an infectious protein?

scientific article

Deletion of the Hsp70 chaperone gene SSB causes hypersensitivity to guanidine toxicity and curing of the [PSI+] prion by increasing guanidine uptake in yeast

scientific article published on 27 March 2003

Distinct structural changes in wild-type and amyloidogenic chicken cystatin caused by disruption of C95-C115 disulfide bond

scientific article published on 2 December 2015

Dysregulated gliotoxin biosynthesis attenuates the production of unrelated biosynthetic gene cluster-encoded metabolites in Aspergillus fumigatus.

scientific article published on 18 December 2017

Ergothioneine Biosynthesis and Functionality in the Opportunistic Fungal Pathogen, Aspergillus fumigatus

scientific article published on 17 October 2016

Gliotoxin effects on fungal growth: mechanisms and exploitation.

scientific article published on March 2012

Global transcript and phenotypic analysis of yeast cells expressing Ssa1, Ssa2, Ssa3 or Ssa4 as sole source of cytosolic Hsp70-Ssa chaperone activity

scientific article

Hsp40 interacts directly with the native state of the yeast prion protein Ure2 and inhibits formation of amyloid-like fibrils

scientific article published on 26 February 2007

Influence of specific HSP70 domains on fibril formation of the yeast prion protein Ure2

scientific article published on 25 March 2013

Insights into the mechanism of how Morin suppresses amyloid fibrillation of hen egg white lysozyme

scientific article published on 21 March 2017

Interplay between Gliotoxin Resistance, Secretion, and the Methyl/Methionine Cycle in Aspergillus fumigatus

scientific article published on 6 July 2015

Is the absence of alpha-helix 2 in the appendant structure region the major contributor to structural instability of human cystatin C?

scientific article published on 16 January 2019

Molecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatus

scientific article (publication date: September 2012)

Molecular dynamics simulation to investigate the impact of disulfide bond formation on conformational stability of chicken cystatin I66Q mutant

scientific article published on 2 October 2012

Molecular dynamics simulations of Hsp40 J-domain mutants identifies disruption of the critical HPD-motif as the key factor for impaired curing in vivo of the yeast prion [URE3].

scientific article published on 2 August 2017

Mutational analysis of Sse1 (Hsp110) suggests an integral role for this chaperone in yeast prion propagation in vivo.

scientific article published on 07 August 2013

Mutational analysis of the Hsp70 substrate-binding domain: correlating molecular-level changes with in vivo function

scientific article published on 20 December 2020

Myricetin prevents fibrillogenesis of hen egg white lysozyme.

scientific article

Propagation of Saccharomyces cerevisiae [PSI+] prion is impaired by factors that regulate Hsp70 substrate binding

scientific article published on May 2004

Protein Folding Activity of the Ribosome is involved in Yeast Prion Propagation

scientific article

Quantitative proteomics reveals the mechanism and consequence of gliotoxin-mediated dysregulation of the methionine cycle in Aspergillus niger

scientific article published on 21 October 2015

RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus

scientific article

Rapid deacetylation of yeast Hsp70 mediates the cellular response to heat stress

scientific article published on 07 November 2019

Reconstructing the fungal tree of life using phylogenomics and a preliminary investigation of the distribution of yeast prion-like proteins in the fungal kingdom.

scientific article

Regulation of nonribosomal peptide synthesis: bis-thiomethylation attenuates gliotoxin biosynthesis in Aspergillus fumigatus

scientific article published on August 2014

Resistance is not futile: gliotoxin biosynthesis, functionality and utility.

scientific article

Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin

scientific article

Steered molecular dynamics simulation of the binding of the bovine auxilin J domain to the Hsc70 nucleotide-binding domain

scientific article

Steered molecular dynamics simulations on the binding of the appendant structure and helix-β2 in domain-swapped human cystatin C dimer

scientific article published on 26 June 2012

Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus

scientific article

Systematic Global Analysis of Genes Encoding Protein Phosphatases in Aspergillus fumigatus.

scientific article published on 5 May 2015

Systems impact of zinc chelation by the epipolythiodioxopiperazine dithiol gliotoxin in Aspergillus fumigatus: a new direction in natural product functionality

scientific article published on 01 June 2018

The Aspergillus fumigatus SchASCH9 kinase modulates SakAHOG1 MAP kinase activity and it is essential for virulence

scientific article published on 19 August 2016

The Aspergillus fumigatus protein GliK protects against oxidative stress and is essential for gliotoxin biosynthesis

scientific article

The C-terminal GGAP motif of Hsp70 mediates substrate recognition and stress response in yeast

scientific article published on 18 September 2018

The double life of the ribosome: When its protein folding activity supports prion propagation

scientific article published on 31 March 2017

The evolutionary history of the genes involved in the biosynthesis of the antioxidant ergothioneine

scientific article published on 26 July 2014

The same but different: the role of Hsp70 in heat shock response and prion propagation

scientific article published on 16 August 2018

The yeast prion protein Ure2: structure, function and folding.

scientific article

The β6/β7 region of the Hsp70 substrate-binding domain mediates heat-shock response and prion propagation

scientific article published on 9 November 2017

Towards understanding the gliotoxin detoxification mechanism: in vivo thiomethylation protects yeast from gliotoxin cytotoxicity

scientific article published on 19 February 2016

Using steered molecular dynamics to predict and assess Hsp70 substrate-binding domain mutants that alter prion propagation

scientific article

Using steered molecular dynamics to study the interaction between ADP and the nucleotide-binding domain of yeast Hsp70 protein Ssa1

scientific article published on 03 November 2018

Yeast models for amyloid disease

scientific article published in January 2014

nuvA, an Aspergillus nidulans gene involved in DNA repair and recombination, is a homologue of Saccharomyces cerevisiae RAD18 and Neurospora crassa uvs-2.

scientific article published on March 1996

List of works by Gary W Jones

(-)-epigallocatechin-3-gallate inhibits fibrillogenesis of chicken cystatin.

A proteomic approach to investigating gene cluster expression and secondary metabolite functionality in Aspergillus fumigatus

A role for cytosolic hsp70 in yeast [PSI(+)] prion propagation and [PSI(+)] as a cellular stress.

Alcohol oxidase (AOX1) from Pichia pastoris is a novel inhibitor of prion propagation and a potential ATPase.

Aspergillus fumigatus protein phosphatase PpzA is involved in iron assimilation, secondary metabolite production, and virulence

Assessment of inactivating stop codon mutations in forty Saccharomyces cerevisiae strains: implications for [PSI] prion- mediated phenotypes

CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression

Chaperoning prions: the cellular machinery for propagating an infectious protein?

Deletion of the Hsp70 chaperone gene SSB causes hypersensitivity to guanidine toxicity and curing of the [PSI+] prion by increasing guanidine uptake in yeast

Distinct structural changes in wild-type and amyloidogenic chicken cystatin caused by disruption of C95-C115 disulfide bond

Dysregulated gliotoxin biosynthesis attenuates the production of unrelated biosynthetic gene cluster-encoded metabolites in Aspergillus fumigatus.

Ergothioneine Biosynthesis and Functionality in the Opportunistic Fungal Pathogen, Aspergillus fumigatus

Gliotoxin effects on fungal growth: mechanisms and exploitation.

Global transcript and phenotypic analysis of yeast cells expressing Ssa1, Ssa2, Ssa3 or Ssa4 as sole source of cytosolic Hsp70-Ssa chaperone activity

Hsp40 interacts directly with the native state of the yeast prion protein Ure2 and inhibits formation of amyloid-like fibrils

Influence of specific HSP70 domains on fibril formation of the yeast prion protein Ure2

Insights into the mechanism of how Morin suppresses amyloid fibrillation of hen egg white lysozyme

Interplay between Gliotoxin Resistance, Secretion, and the Methyl/Methionine Cycle in Aspergillus fumigatus

Is the absence of alpha-helix 2 in the appendant structure region the major contributor to structural instability of human cystatin C?

Molecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatus

Molecular dynamics simulation to investigate the impact of disulfide bond formation on conformational stability of chicken cystatin I66Q mutant

Molecular dynamics simulations of Hsp40 J-domain mutants identifies disruption of the critical HPD-motif as the key factor for impaired curing in vivo of the yeast prion [URE3].

Mutational analysis of Sse1 (Hsp110) suggests an integral role for this chaperone in yeast prion propagation in vivo.

Mutational analysis of the Hsp70 substrate-binding domain: correlating molecular-level changes with in vivo function

Myricetin prevents fibrillogenesis of hen egg white lysozyme.

Propagation of Saccharomyces cerevisiae [PSI+] prion is impaired by factors that regulate Hsp70 substrate binding

Protein Folding Activity of the Ribosome is involved in Yeast Prion Propagation

Quantitative proteomics reveals the mechanism and consequence of gliotoxin-mediated dysregulation of the methionine cycle in Aspergillus niger

RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus

Rapid deacetylation of yeast Hsp70 mediates the cellular response to heat stress

Reconstructing the fungal tree of life using phylogenomics and a preliminary investigation of the distribution of yeast prion-like proteins in the fungal kingdom.

Regulation of nonribosomal peptide synthesis: bis-thiomethylation attenuates gliotoxin biosynthesis in Aspergillus fumigatus

Resistance is not futile: gliotoxin biosynthesis, functionality and utility.

Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin

Steered molecular dynamics simulation of the binding of the bovine auxilin J domain to the Hsc70 nucleotide-binding domain

Steered molecular dynamics simulations on the binding of the appendant structure and helix-β2 in domain-swapped human cystatin C dimer

Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus

Systematic Global Analysis of Genes Encoding Protein Phosphatases in Aspergillus fumigatus.

Systems impact of zinc chelation by the epipolythiodioxopiperazine dithiol gliotoxin in Aspergillus fumigatus: a new direction in natural product functionality

The Aspergillus fumigatus SchASCH9 kinase modulates SakAHOG1 MAP kinase activity and it is essential for virulence

The Aspergillus fumigatus protein GliK protects against oxidative stress and is essential for gliotoxin biosynthesis

The C-terminal GGAP motif of Hsp70 mediates substrate recognition and stress response in yeast

The double life of the ribosome: When its protein folding activity supports prion propagation

The evolutionary history of the genes involved in the biosynthesis of the antioxidant ergothioneine

The same but different: the role of Hsp70 in heat shock response and prion propagation

The yeast prion protein Ure2: structure, function and folding.

The β6/β7 region of the Hsp70 substrate-binding domain mediates heat-shock response and prion propagation

Towards understanding the gliotoxin detoxification mechanism: in vivo thiomethylation protects yeast from gliotoxin cytotoxicity

Using steered molecular dynamics to predict and assess Hsp70 substrate-binding domain mutants that alter prion propagation

Using steered molecular dynamics to study the interaction between ADP and the nucleotide-binding domain of yeast Hsp70 protein Ssa1

Yeast models for amyloid disease

nuvA, an Aspergillus nidulans gene involved in DNA repair and recombination, is a homologue of Saccharomyces cerevisiae RAD18 and Neurospora crassa uvs-2.