List of works - Dave Bridges

A peer evaluation training results in high-quality feedback, as measured over time in nutritional sciences graduate students

scientific article published on 01 June 2020

AMPK directly activates mTORC2 to promote cell survival during acute energetic stress

scientific article published on 11 June 2019

An estrogen receptor β-selective agonist inhibits non-alcoholic steatohepatitis in preclinical models by regulating bile acid and xenobiotic receptors

scientific article published on January 2017

Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy.

scientific article published on 27 April 2017

Characterization of neurons from immortalized dental pulp stem cells for the study of neurogenetic disorders

scientific article

Cyclic nucleotide binding proteins in the Arabidopsis thaliana and Oryza sativa genomes

scientific article

Cytochrome P450 1B1 Contributes to the Development of Atherosclerosis and Hypertension in Apolipoprotein E-Deficient Mice

scientific article

Detection of multiple splice variants of the nuclear protein phosphatase 1 regulator sds22 in rat liver nuclei

scientific article published on 01 January 2002

Disruption of brain-derived neurotrophic factor production from individual promoters generates distinct body composition phenotypes in mice

scientific article published on 25 September 2018

Docosahexaenoic acid inhibits proteolytic processing of sterol regulatory element-binding protein-1c (SREBP-1c) via activation of AMP-activated kinase.

scientific article published on 28 August 2015

Exposure to environmentally persistent free radicals during gestation lowers energy expenditure and impairs skeletal muscle mitochondrial function in adult mice.

scientific article published on 26 April 2016

Gene Expression Signature in Adipose Tissue of Acromegaly Patients

scientific article published on 18 June 2015

Gene expression changes in subcutaneous adipose tissue due to Cushing's disease.

scientific article

Gene expression signature in adipose tissue of acromegaly patients

article

Glucocorticoid-Induced Metabolic Disturbances Are Exacerbated in Obese Male Mice.

scientific article

Glycogen synthase kinase-3-mediated phosphorylation of serine 73 targets sterol response element binding protein-1c (SREBP-1c) for proteasomal degradation

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Higher baseline expression of the PTGS2 gene and greater decreases in total colonic fatty acid content predict greater decreases in colonic prostaglandin-E2 concentrations after dietary supplementation with ω-3 fatty acids

scientific article published on 02 November 2018

Identification and characterization of D-AKAP1 as a major adipocyte PKA and PP1 binding protein

scientific journal article

In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P.

scientific article

Inhibition of AMPK catabolic action by GSK3.

scientific article published on 25 April 2013

Insulin stimulates phosphatidylinositol 3-phosphate production via the activation of Rab5

scientific article

Metabolic crosstalk: molecular links between glycogen and lipid metabolism in obesity

scientific article

Obesity Augments Glucocorticoid-Dependent Muscle Atrophy in Male C57BL/6J Mice

scientific article published on 15 October 2020

Pharmacologic activation of estrogen receptor β increases mitochondrial function, energy expenditure, and brown adipose tissue

scientific article published on 12 October 2016

Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1 ⬇️

scientific article published on June 13, 2012

Phosphoinositides: Key modulators of energy metabolism

scientific article

Phosphorylation of sterol regulatory element binding protein-1a by protein kinase A (PKA) regulates transcriptional activity

scientific article published on 20 May 2014

Purification of a plant nucleotide pyrophosphatase as a protein that interferes with nitrate reductase and glutamine synthetase assays

scientific article published in March 2003

Rab5 proteins regulate activation and localization of target of rapamycin complex 1.

scientific article

Roles for PI(3,5)P2 in nutrient sensing through TORC1.

scientific article published on 29 January 2014

Secretory phospholipase A2 group IIA modulates insulin sensitivity and metabolism.

scientific article

Sex-specific differences in hepatic steatosis in obese spontaneously hypertensive (SHROB) rats

scientific article published on 10 September 2018

Significant transcriptional changes in 15q duplication but not Angelman syndrome deletion stem cell-derived neurons.

scientific article published on 27 January 2018

TC10 is regulated by caveolin in 3T3-L1 adipocytes

scientific article

The Signaling Pathways Project, an integrated 'omics knowledgebase for mammalian cellular signaling pathways

scientific article published on 31 October 2019

The lipid kinase PI4KIIIβ is highly expressed in breast tumors and activates Akt in cooperation with Rab11a

scientific article

The p11 subunit of annexin II heterotetramer is regulated by basic carboxypeptidase

scientific article

The role of TORC1 in muscle development in Drosophila

scientific article

The trichloroethylene metabolite S-(1,2-dichlorovinyl)-L-cysteine induces progressive mitochondrial dysfunction in HTR-8/SVneo trophoblasts

scientific article published on 30 August 2019

Transcriptional profiling of the response to the trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine revealed activation of the eIF2α/ATF4 integrated stress response in two in vitro placental models

scientific article published in 2021

Tuberous sclerosis complex exhibits a new renal cystogenic mechanism

scientific article published on 01 January 2019

Weight loss effects of methotrexate and cyclophosphamide.

scientific article published on 10 January 2016

Zinc finger protein 407 (ZFP407) regulates insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) mRNA

scientific article

Zinc finger protein 407 overexpression upregulates PPAR target gene expression and improves glucose homeostasis in mice.

scientific article published on 13 September 2016

p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity

scientific journal article

List of works by Dave Bridges

A peer evaluation training results in high-quality feedback, as measured over time in nutritional sciences graduate students

AMPK directly activates mTORC2 to promote cell survival during acute energetic stress

An estrogen receptor β-selective agonist inhibits non-alcoholic steatohepatitis in preclinical models by regulating bile acid and xenobiotic receptors

Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy.

Characterization of neurons from immortalized dental pulp stem cells for the study of neurogenetic disorders

Cyclic nucleotide binding proteins in the Arabidopsis thaliana and Oryza sativa genomes

Cytochrome P450 1B1 Contributes to the Development of Atherosclerosis and Hypertension in Apolipoprotein E-Deficient Mice

Detection of multiple splice variants of the nuclear protein phosphatase 1 regulator sds22 in rat liver nuclei

Disruption of brain-derived neurotrophic factor production from individual promoters generates distinct body composition phenotypes in mice

Docosahexaenoic acid inhibits proteolytic processing of sterol regulatory element-binding protein-1c (SREBP-1c) via activation of AMP-activated kinase.

Exposure to environmentally persistent free radicals during gestation lowers energy expenditure and impairs skeletal muscle mitochondrial function in adult mice.

Gene Expression Signature in Adipose Tissue of Acromegaly Patients

Gene expression changes in subcutaneous adipose tissue due to Cushing's disease.

Gene expression signature in adipose tissue of acromegaly patients

Glucocorticoid-Induced Metabolic Disturbances Are Exacerbated in Obese Male Mice.

Glycogen synthase kinase-3-mediated phosphorylation of serine 73 targets sterol response element binding protein-1c (SREBP-1c) for proteasomal degradation

Guidelines for the use and interpretation of assays for monitoring autophagy

Higher baseline expression of the PTGS2 gene and greater decreases in total colonic fatty acid content predict greater decreases in colonic prostaglandin-E2 concentrations after dietary supplementation with ω-3 fatty acids

Identification and characterization of D-AKAP1 as a major adipocyte PKA and PP1 binding protein

In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P.

Inhibition of AMPK catabolic action by GSK3.

Insulin stimulates phosphatidylinositol 3-phosphate production via the activation of Rab5

Metabolic crosstalk: molecular links between glycogen and lipid metabolism in obesity

Obesity Augments Glucocorticoid-Dependent Muscle Atrophy in Male C57BL/6J Mice

Pharmacologic activation of estrogen receptor β increases mitochondrial function, energy expenditure, and brown adipose tissue

Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1 ⬇️

Phosphoinositides: Key modulators of energy metabolism

Phosphorylation of sterol regulatory element binding protein-1a by protein kinase A (PKA) regulates transcriptional activity

Purification of a plant nucleotide pyrophosphatase as a protein that interferes with nitrate reductase and glutamine synthetase assays

Rab5 proteins regulate activation and localization of target of rapamycin complex 1.

Roles for PI(3,5)P2 in nutrient sensing through TORC1.

Secretory phospholipase A2 group IIA modulates insulin sensitivity and metabolism.

Sex-specific differences in hepatic steatosis in obese spontaneously hypertensive (SHROB) rats

Significant transcriptional changes in 15q duplication but not Angelman syndrome deletion stem cell-derived neurons.

TC10 is regulated by caveolin in 3T3-L1 adipocytes

The Signaling Pathways Project, an integrated 'omics knowledgebase for mammalian cellular signaling pathways

The lipid kinase PI4KIIIβ is highly expressed in breast tumors and activates Akt in cooperation with Rab11a

The p11 subunit of annexin II heterotetramer is regulated by basic carboxypeptidase

The role of TORC1 in muscle development in Drosophila

The trichloroethylene metabolite S-(1,2-dichlorovinyl)-L-cysteine induces progressive mitochondrial dysfunction in HTR-8/SVneo trophoblasts

Transcriptional profiling of the response to the trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine revealed activation of the eIF2α/ATF4 integrated stress response in two in vitro placental models

Tuberous sclerosis complex exhibits a new renal cystogenic mechanism

Weight loss effects of methotrexate and cyclophosphamide.

Zinc finger protein 407 (ZFP407) regulates insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) mRNA

Zinc finger protein 407 overexpression upregulates PPAR target gene expression and improves glucose homeostasis in mice.

p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity