Search filters

List of works by Ignacio Pérez de Castro

A SUMOylation Motif in Aurora-A: Implications for Spindle Dynamics and Oncogenesis

scientific article published on 14 December 2011

A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy

scientific article published on 27 January 2007

An AC-repeat adjacent to mouse Cdkn2B allows the detection of specific allelic losses in the p15INK4b and p16INK4a tumor suppressor genes.

scientific article published in March 1998

Aurora A drives early signalling and vesicle dynamics during T-cell activation

scientific article

Aurora B Overexpression Causes Aneuploidy and p21Cip1 Repression during Tumor Development

scientific article

Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21(Cip1).

scientific article published on 21 February 2013

Aurora kinase A inhibitors: promising agents in antitumoral therapy

scientific article published on 09 September 2014

Cellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)

scientific journal article

Combinatorial effects of microRNAs to suppress the Myc oncogenic pathway

scientific article

Concurrent positive association between pathological gambling and functional DNA polymorphisms at the MAO-A and the 5-HT transporter genes.

scientific article published in January 2002

Cooperative alterations of Rb pathway regulators in mouse primary T cell lymphomas

scientific article published on 01 September 1999

Editorial: Aurora Kinases: Classical Mitotic Roles, Non-Canonical Functions and Translational Views

scientific article published on 22 March 2017

Eight new polymorphic microsatellites in mouse gene loci ⬇️

scientific article published on 01 January 1995

Emerging cancer therapeutic opportunities by inhibiting mitotic kinases

scientific article published on 30 July 2008

Familial cosegregation of manic-depressive illness and a form of hereditary cerebellar ataxia

scientific article published on 01 June 1995

Frequent allelic losses of 9p21 markers and low incidence of mutations at p16(CDKN2) gene in non-Hodgkin lymphomas of B-cell lineage

article

Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression

scientific article

Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development.

scientific article published on 25 May 2011

Genetics of pathological gambling.

scientific article

Hypermethylation of the cell cycle inhibitor p15INK4b 3'-untranslated region interferes with its transcriptional regulation in primary lymphomas.

scientific article published in January 1999

Liver organoids reproduce alpha-1 antitrypsin deficiency-related liver disease

scientific article published on 13 December 2019

Mitotic Stress and Chromosomal Instability in Cancer: The Case for TPX2 ⬇️

scientific article published on November 1, 2012

NF1 modulates the effects of Ras oncogenes: evidence of other NF1 function besides its GAP activity

scientific article published on November 2003

PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis.

scientific article published on February 2006

Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1

scientific article

Phosphorylation of targeting protein for Xenopus kinesin-like protein 2 (TPX2) at threonine 72 in spindle assembly

scientific article published on 16 February 2015

Psychiatric comorbidity in pathological gamblers seeking treatment.

scientific article published in October 2001

Ras activation in Jurkat T cells following low-grade stimulation of the T-cell receptor is specific to N-Ras and occurs only on the Golgi apparatus.

scientific article published on April 2004

Requirements for Aurora-A in tissue regeneration and tumor development in adult mammals

scientific article published in November 2013

SUMOylation modulates the function of Aurora-B kinase

scientific article

Systemic tumor targeting and killing by Sindbis viral vectors

scientific article published on 30 November 2003

Targeting cell cycle kinases for cancer therapy

scientific article published on January 2007

The EGFR-TMEM167A-p53 Axis Defines the Aggressiveness of Gliomas

scientific article published on 14 January 2020

The Rgr oncogene induces tumorigenesis in transgenic mice

scientific article published on September 2004

Tpx2 controls spindle integrity, genome stability, and tumor development

scientific article published on 20 January 2012

p15(INK4b) plays a crucial role in murine lymphoid development and tumorigenesis

scientific article published on 6 January 2012

Paulina is supported by:

About Paulina

Help