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List of works by Barbara Bottazzi

A chemoattractant expressed in human sarcoma cells (tumor-derived chemotactic factor, TDCF) is identical to monocyte chemoattractant protein-1/monocyte chemotactic and activating factor (MCP-1/MCAF)

scientific article

A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation).

scientific article

A new surface plasmon resonance-based immunoassay for rapid, reproducible and sensitive quantification of pentraxin-3 in human plasma

scientific article

A paracrine circuit in the regulation of the proliferation of macrophages infiltrating murine sarcomas

scientific article published on 01 March 1990

A single amino acid substitution in the hemagglutinin of H3N2 subtype influenza A viruses is associated with resistance to the long pentraxin PTX3 and enhanced virulence in mice

scientific article published on 4 December 2013

Activation of double-stranded RNA dependent protein kinase by ribosomal RNA precursors

scientific article

Alveolar pentraxin 3 as an early marker of microbiologically confirmed pneumonia: a threshold-finding prospective observational study

scientific article

An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode

scientific article published on 11 May 2015

An integrated view of humoral innate immunity: pentraxins as a paradigm

scientific article

Anti-rheumatic treatment is not associated with reduction of pentraxin 3 in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis

scientific article

Antiviral activity of the long chain pentraxin PTX3 against influenza viruses

scientific article

Autocrine Production of IL-10 Mediates Defective IL-12 Production and NF- B Activation in Tumor-Associated Macrophages

article

Binding of the long pentraxin PTX3 to factor H: interacting domains and function in the regulation of complement activation

scientific journal article

Biochemical and functional characterization of the interaction between pentraxin 3 and C1q.

scientific article

Biomarkers of oxidative-stress and inflammation in exhaled breath condensate from hospital cleaners

scientific article published on 9 December 2015

Cell-specific regulation of PTX3 by glucocorticoid hormones in hematopoietic and nonhematopoietic cells

scientific article published on 14 August 2008

Characterization of spontaneous metastases from autochthonous 3-methylcholanthrene-induced tumors

Chemotactic activity for mononuclear phagocytes of culture supernatants from murine and human tumor cells: evidence for a role in the regulation of the macrophage content of neoplastic tissues

scientific article published in January 1983

Circulating levels of the long pentraxin PTX3 correlate with severity of infection in critically ill patients

scientific article

Complement Dependent Amplification of the Innate Response to a Cognate Microbial Ligand by the Long Pentraxin PTX3

scientific article published on 01 November 2007

Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors

scientific article published in May 2005

Correction: Early and Transient Release of Leukocyte Pentraxin 3 during Acute Myocardial Infarction

Correction: The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa

scholarly article by Federica Moalli et al published 6 June 2011 in Journal of Immunology

Cytokine regulation of monocyte recruitment.

scientific article

Cytokine regulation of tumour-associated macrophages.

scientific article

Defective expression of the monocyte chemotactic protein-1 receptor CCR2 in macrophages associated with human ovarian carcinoma

scientific article

Detection of Anti-Pentraxin-3 Autoantibodies in ANCA-Associated Vasculitis

scientific article published on 21 January 2016

Development of 'Redox Arrays' for identifying novel glutathionylated proteins in the secretome.

scientific article published on 29 September 2015

Driver mutations (JAK2V617F, MPLW515L/K or CALR), pentraxin-3 and C-reactive protein in essential thrombocythemia and polycythemia vera

scientific article published on 22 February 2017

Dynamic induction of the long pentraxin PTX3 in the CNS after limbic seizures: evidence for a protective role in seizure-induced neurodegeneration

scientific article published in January 2001

Early and transient release of leukocyte pentraxin 3 during acute myocardial infarction

scientific article

Echocardiography, spirometry, and systemic acute-phase inflammatory proteins in smokers with COPD or CHF: an observational study

scientific article

Effect of hydrocortisone on the macrophage content, growth and metastasis of transplanted murine tumors

scientific article published on January 1984

Elevations of inflammatory markers PTX3 and sST2 after resuscitation from cardiac arrest are associated with multiple organ dysfunction syndrome and early death

scientific article published on 14 March 2015

Endogenous PTX3 translocates at the membrane of late apoptotic human neutrophils and is involved in their engulfment by macrophages

Endothelial cell-derived pentraxin 3 limits the vasoreparative therapeutic potential of circulating angiogenic cells

scientific article

Expression of c-fos proto-oncogene in tumor-associated macrophages

scientific article published on June 1990

Failure of warfarin to affect the tissue factor activity and the metastatic potential of murine fibrosarcoma cells

scientific article published on 01 February 1985

Failure to detect production of IL-10 by activated human neutrophils

article

Granulocyte colony-stimulating factor (G-CSF) gene transduction in murine adenocarcinoma drives neutrophil-mediated tumor inhibition in vivo. Neutrophils discriminate between G-CSF-producing and G-CSF-nonproducing tumor cells ⬇️

scientific article published on July 1, 1992

Human renal epithelial cells produce the long pentraxin PTX3.

scientific article published in February 2005

Identification of MIP-1 alpha/LD78 as a monocyte chemoattractant released by the HTLV-I-transformed cell line MT4.

scientific article published on January 1995

Identification of an antiangiogenic FGF2-binding site in the N terminus of the soluble pattern recognition receptor PTX3.

scientific article published on 12 June 2006

Immune characterization of long pentraxin 3 in pigs infected with influenza virus

scientific article published on 22 October 2013

Impairment of cytokine production in mice fed a vitamin D3-deficient diet

scientific article published on August 1991

In vitro migration of human large granular lymphocytes

scientific article published on April 1985

In vitro migration of rat large granular lymphocytes

scientific article

Increased levels of serum pentraxin 3, a novel cardiovascular biomarker, in patients with inflammatory rheumatic disease

scientific article published in March 2010

Increased long-term expression of pentraxin 3 in irradiated human arteries and veins compared to internal controls from free tissue transfers

scientific article published on 23 September 2013

Increased peripheral benzodiazepine binding sites and pentraxin 3 expression in the spinal cord during EAE: relation to inflammatory cytokines and modulation by dexamethasone and rolipram

scientific article published on 01 September 2000

Inducible expression of PTX3, a new member of the pentraxin family, in human mononuclear phagocytes.

scientific article

Inducible expression of the long pentraxin PTX3 in the central nervous system.

scientific article

Inflammation and thrombosis in essential thrombocythemia and polycythemia vera: different role of C-reactive protein and pentraxin 3.

scientific article

Inflammatory Long Pentraxin 3 is Associated with Leukocyte Telomere Length in Night-Shift Workers

scientific article

Inflammatory and Innate Immune Cells in Cancer Microenvironment and Progression

Influence of pentraxin 3 (PTX3) genetic variants on myocardial infarction risk and PTX3 plasma levels

scientific article

Interaction of C1q with IgG1, C-reactive protein and pentraxin 3: mutational studies using recombinant globular head modules of human C1q A, B, and C chains

scientific article published on April 2006

Interactions of the humoral pattern recognition molecule PTX3 with the complement system ⬇️

scientific article published on November 1, 2012

Interleukin-1-inducible genes in endothelial cells. Cloning of a new gene related to C-reactive protein and serum amyloid P component

scientific article

Long pentraxin 3/tumor necrosis factor-stimulated gene-6 interaction: a biological rheostat for fibroblast growth factor 2-mediated angiogenesis

scientific journal article

Macrophage expression and prognostic significance of the long pentraxin PTX3 in COVID-19

scientific article published on 18 November 2020

Macrophage infiltration and growth of sarcoma clones expressing different amounts of monocyte chemotactic protein/JE.

scientific article published on September 1991

Membrane and soluble pattern recognition receptors: the unique functions of the long pentraxin PTX3

scholarly article published December 2004

Membrane fluidity affects tumor-cell motility, invasion and lung-colonizing potential

scientific article published on 01 October 1989

Mesenchymal Stromal Cell-Derived PTX3 Promotes Wound Healing via Fibrin Remodeling

scientific article published in January 2016

Migratory capacity of large granular lymphocytes from T-gamma-lymphoproliferative disorders

Modulation of the locomotory capacity of human large granular lymphocytes

scientific article published on 01 August 1986

Molecular Signatures of Immunity and Immunogenicity in Infection and Vaccination

scientific article published on 15 November 2017

Monocyte chemotactic cytokine gene transfer modulates macrophage infiltration, growth, and susceptibility to IL-2 therapy of a murine melanoma

scientific article published in February 1992

Monocyte chemotactic protein-1 (MCP-1): signal transduction and involvement in the regulation of macrophage traffic in normal and neoplastic tissues

scientific article published on 01 January 1993

Monocyte function in intravenous drug abusers with lymphadenopathy syndrome and in patients with acquired immunodeficiency syndrome: selective impairment of chemotaxis

scientific article published on 01 October 1985

Multimer formation and ligand recognition by the long pentraxin PTX3. Similarities and differences with the short pentraxins C-reactive protein and serum amyloid P component.

scientific article published in December 1997

Multiplexed label-free optical biosensor for medical diagnostics

scientific article published in January 2014

Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response

scientific article

Origin and regulation of tumor-associated macrophages: the role of tumor-derived chemotactic factor

scientific article published on August 1986

PTX3 Binds MD-2 and Promotes TRIF-Dependent Immune Protection in Aspergillosis

PTX3 as a paradigm for the interaction of pentraxins with the complement system

scientific article published on February 2013

PTX3 interacts with inter-alpha-trypsin inhibitor: implications for hyaluronan organization and cumulus oophorus expansion

scientific article published on 2 August 2007

PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization

scientific article

PTX3, a Humoral Pattern Recognition Molecule, in Innate Immunity, Tissue Repair, and Cancer

scientific article published in April 2018

PTX3, a humoral pattern recognition molecule at the interface between microbe and matrix recognition

scientific article

Pandemic H1N1 influenza A viruses are resistant to the antiviral activities of innate immune proteins of the collectin and pentraxin superfamilies

scientific article

Pathogen Recognition by the Long Pentraxin PTX3 ⬇️

scientific article published on June 2, 2011

Pattern recognition by pentraxins

scientific article

Pentraxin 3 (PTX3) inhibits plasma cell/stromal cell cross-talk in the bone marrow of multiple myeloma patients

scientific article

Pentraxin 3 (PTX3) plasma levels and carotid intima media thickness progression in the general population

scientific article published on 4 December 2013

Pentraxin 3 in Cardiovascular Disease

Pentraxin 3 in patients with severe sepsis or shock: the ALBIOS trial

scientific article

Pentraxin 3 inhibits fibroblast growth factor 2-dependent activation of smooth muscle cells in vitro and neointima formation in vivo

scientific article published on 14 July 2005

Pentraxin 3 plasma levels at graft-versus-host disease onset predict disease severity and response to therapy in children given haematopoietic stem cell transplantation

scientific article

Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1-integrin

scientific article published on 05 November 2018

Pentraxin 3, a non-redundant soluble pattern recognition receptor involved in innate immunity

scientific article

Pentraxin 3, a novel cardiovascular biomarker, is expressed in aortic specimens of patients with coronary artery disease with and without rheumatoid arthritis

scholarly article by Ivana Hollan et al published September 2013 in Cardiovascular Pathology

Pentraxin-3 as a marker of advanced atherosclerosis results from the Bruneck, ARMY and ARFY Studies

scientific article

Pentraxin-3 in chronic heart failure: the CORONA and GISSI-HF trials

scientific article published on 27 June 2012

Pentraxin-3 is upregulated in the central nervous system during MS and EAE, but does not modulate experimental neurological disease

scientific article published on 18 November 2015

Pentraxins and Atherosclerosis

Pentraxins and atherosclerosis: the role of PTX3.

scientific article published on January 2011

Pentraxins as a key component of innate immunity

scientific article

Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility

scientific article

Pentraxins in Innate Immunity and Inflammation

Pentraxins in Vascular Pathology: The Role of PTX3

scholarly article

Pentraxins in humoral innate immunity

scientific article published on January 2012

Pentraxins in innate immunity and inflammation

scientific article published on January 2006

Pentraxins in innate immunity: from C-reactive protein to the long pentraxin PTX3.

scientific article

Pentraxins in innate immunity: lessons from PTX3.

scientific article published on 04 August 2010

Pentraxins in the activation and regulation of innate immunity

scientific article

Pentraxins, humoral innate immunity and tissue injury

scientific article published on 23 June 2008

Pentraxins: multifunctional proteins at the interface of innate immunity and inflammation

scientific article published on March 2009

Plasma complement and vascular complement deposition in patients with coronary artery disease with and without inflammatory rheumatic diseases

scientific article

Plasma levels of pentraxin-3, an acute phase protein, are increased during sickle cell painful crisis

article

Plasma pentraxin-3 as a marker of bioincompatibility in hemodialysis patients

scientific article published on 01 January 2012

Plasminogen activator activity of metastatic variants from a murine fibrosarcoma; effect of thrombinin vitro

scientific article published on 01 July 1983

Production of the Long Pentraxin PTX3 by Myeloid Dendritic Cells: Linking Cellular and Humoral Innate Immunity

Production of the long pentraxin PTX3 in advanced atherosclerotic plaques

scientific article

Proteolytic cleavage of the long pentraxin PTX3 in the airways of cystic fibrosis patients

scientific article published on 8 March 2013

Protooncogene expression in normal and tumor-infiltrating phagocytes

scientific article published on 01 December 1987

Prototypic long pentraxin PTX3 is present in breast milk, spreads in tissues, and protects neonate mice from Pseudomonas aeruginosa lung infection

scientific article published on 17 July 2013

Recognition of Neisseria meningitidis by the long pentraxin PTX3 and its role as an endogenous adjuvant

scientific article

Regulation of PTX3, a key component of humoral innate immunity in human dendritic cells: stimulation by IL-10 and inhibition by IFN-

scientific article published on 03 February 2006

Regulation of leukocyte recruitment by the long pentraxin PTX3.

scientific article published on 7 March 2010

Regulation of the macrophage content of neoplasms by chemoattractants

scientific article published in Science

Ribosomal RNA metabolism in macrophages

scientific article published on January 1, 1992

Role of complement and Fc receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus

scientific article published on 09 September 2010

Role of tumor proteinases in tumor cell-induced platelet aggregation

scientific article published on 01 January 1986

Selective recognition of fibroblast growth factor-2 by the long pentraxin PTX3 inhibits angiogenesis

scientific article published on 18 March 2004

Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus

scientific article published on 18 June 2021

Serum amyloid P is a sialylated glycoprotein inhibitor of influenza A viruses

scientific article

Structural and Functional Characterization of a Single-Chain Form of the Recognition Domain of Complement Protein C1q.

scientific article published on 2 March 2016

Structural characterization of PTX3 disulfide bond network and its multimeric status in cumulus matrix organization

scientific article published on 25 January 2008

Systemic pentraxin-3 levels reflect vascular enhancement and progression in Takayasu arteritis

scientific article

The "sweet" side of a long pentraxin: how glycosylation affects PTX3 functions in innate immunity and inflammation

scientific article published on January 2012

The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair.

scientific article

The Long Pentraxin PTX3 as a Humoral Innate Immunity Functional Player and Biomarker of Infections and Sepsis

The Long Pentraxin PTX3 as a Link Between Innate Immunity, Tissue Remodeling, and Cancer

The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa

scientific article published on 25 March 2011

The angiogenic inhibitor long pentraxin PTX3 forms an asymmetric octamer with two binding sites for FGF2

scientific journal article

The long pentraxin PTX3 as a link among innate immunity, inflammation, and female fertility

scientific article

The long pentraxin PTX3 as a prototypic humoral pattern recognition receptor: interplay with cellular innate immunity

scientific article published on January 2009

The long pentraxin PTX3 at the crossroads between innate immunity and tissue remodelling

scientific article published on April 2011

The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells

scientific article

The long pentraxin PTX3 in vascular pathology

scientific article published on 23 August 2006

The long pentraxin PTX3: a paradigm for humoral pattern recognition molecules

scientific article published on 25 March 2013

The macrophage content of tumors is unrelated to levels of NK cell-mediated resistance

scientific article published in January 1986

The origin and function of tumor-associated macrophages

scientific article

The pentraxins PTX3 and SAP in innate immunity, regulation of inflammation and tissue remodelling

scientific article

The role of macrophages in the regulation of primary tumor growth

scientific article published on January 1991

The signal transduction pathway involved in the migration induced by a monocyte chemotactic cytokine

scientific article published in October 1991

The yin-yang of long pentraxin PTX3 in inflammation and immunity

scientific article published on May 2014

Tumor-associated macrophages in metastasizing tumors.

scientific article published on January 1988

Tumor-derived chemotactic factor(s) from human ovarian carcinoma: evidence for a role in the regulation of macrophage content of neoplastic tissues.

scientific article

Tumoricidal and immunoregulatory activity of macrophages from human ovarian carcinomas

scientific article published on 01 January 1982

Vaccination of mice for research purpose: alum is as effective as and safer than complete Freund adjuvant

scientific article published on 20 December 2012

Vascular pentraxin 3 controls arterial thrombosis by targeting collagen and fibrinogen induced platelets aggregation

scientific article published on 11 March 2016

p50 Nuclear Factor- B Overexpression in Tumor-Associated Macrophages Inhibits M1 Inflammatory Responses and Antitumor Resistance

article

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