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List of works by Edna Grünblatt

1.011 Early diagnosis for Parkinson's disease according to whole blood gene profile

article

1.100 Early diagnosis for Parkinson's disease according to whole blood gene profile

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1.12.1 PARKINSON'S DISEASE: MOLECULAR RISK FACTORS

scholarly article by Edna Grünblatt published January 2012 in Parkinsonism and Related Disorders

5-HT2A serotonin receptor agonist DOI alleviates cytotoxicity in neuroblastoma cells: Role of the ERK pathway ⬇️

scientific article published on February 2013

A Single Dose of LSD Does Not Alter Gene Expression of the Serotonin 2A Receptor Gene (HTR2A) or Early Growth Response Genes (EGR1-3) in Healthy Subjects

scientific article

A molecular signature in blood identifies early Parkinson's disease

scientific article

A pilot investigation on DNA methylation modifications associated with complex posttraumatic symptoms in elderly traumatized in childhood.

scientific article published on 19 December 2017

A systematic meta-analysis of the association of Neuregulin 1 (NRG1), D-amino acid oxidase (DAO), and DAO activator (DAOA)/G72 polymorphisms with schizophrenia

scientific article published in September 2017

Aldehyde dehydrogenase (ALDH) in Alzheimer's and Parkinson's disease

scientific article

Aldehyde dehydrogenase 2 in sporadic Parkinson's disease

scientific article published on 01 January 2014

Alteration of the pro-oxidant xanthine oxidase (XO) in the thalamus and occipital cortex of patients with schizophrenia

scientific article published on 15 November 2010

Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer's disease.

scientific article published in March 2007

Altered glial cell line-derived neurotrophic factor (GDNF) concentrations in the brain of patients with depressive disorder: a comparative post-mortem study

scientific article

Altered mRNA expression of monoaminergic candidate genes in the blood of children with attention deficit hyperactivity disorder and autism spectrum disorder

scientific article

Altered peripheral BDNF mRNA expression and BDNF protein concentrations in blood of children and adolescents with autism spectrum disorder

scientific article published on 6 February 2014

Alzheimer's disease and type 2 diabetes: two diseases, one common link?

scientific article

An overview of the first 5 years of the ENIGMA obsessive-compulsive disorder working group: The power of worldwide collaboration

scientific article published on 10 March 2020

Apomorphine protects against MPTP-induced neurotoxicity in mice

scientific article

Association Study of the 5-HTTLPR Polymorphism and Depression in 75-Year-Old Nondemented Subjects From the Vienna Transdanube Aging (VITA) Study

Association of a functional NOS1 promoter repeat with Alzheimer's disease in the VITA cohort

scientific article published in January 2011

Association study and a systematic meta-analysis of the VNTR polymorphism in the 3'-UTR of dopamine transporter gene and attention-deficit hyperactivity disorder

article

Association study in siblings and case-controls of serotonin- and oxytocin-related genes with high functioning autism.

scientific article published on 24 January 2014

Association study of BDNF and CNTF polymorphism to depression in non-demented subjects of the "VITA" study

scientific article published on 22 June 2006

Association study of the 5-HTTLPR polymorphism and depression in 75-Year-Old nondemented subjects from the Vienna Transdanube Aging (VITA) study

scientific article published in September 2006

Astrocyte- and Microglia-Specific Mitochondrial DNA Deletions Levels in Sporadic Alzheimer's Disease

scientific article published on 01 January 2019

Autism spectrum disorder associated with low serotonin in CSF and mutations in the SLC29A4 plasma membrane monoamine transporter (PMAT) gene

scientific article

Behavioural and expressional phenotyping of nitric oxide synthase-I knockdown animals.

scientific article published on January 2007

Biological markers for anxiety disorders, OCD and PTSD - a consensus statement. Part I: Neuroimaging and genetics

scientific article

Biological markers for anxiety disorders, OCD and PTSD: A consensus statement. Part II: Neurochemistry, neurophysiology and neurocognition

scientific article published on 15 July 2016

Biostatistical analysis of gene microarrays reveals diverse expression clusters between macaque subspecies in brain SIV infection.

scientific article published in January 2007

Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein

scientific article published in May 2007

Brain tryptophan rather than pH-value is altered as consequence of artificial postmortem interval and storage conditions

scientific article published on 15 September 2010

CNTNAP2 gene in high functioning autism: no association according to family and meta-analysis approaches

scientific article published on 11 November 2015

Can enzyme kinetics of prooxidants teach us a lesson about the treatment of Alzheimer's disease: a pilot post-mortem study

scientific article published in June 2010

Changes in the expression of genes related to neuroinflammation over the course of sporadic Alzheimer's disease progression: CX3CL1, TREM2, and PPARγ.

scientific article published on 18 January 2015

Characterization of cognitive deficits in spontaneously hypertensive rats, accompanied by brain insulin receptor dysfunction

scientific article published on 4 June 2015

Chronic exogenous corticosterone administration generates an insulin-resistant brain state in rats

scientific article published in March 2010

Chronic monoamine oxidase-B inhibitor treatment blocks monoamine oxidase-A enzyme activity

scientific article published on 23 November 2013

Cognitive, behavioral and metabolic effects of oral galactose treatment in the transgenic Tg2576 mice

scientific article published on 17 December 2018

Combining genetic and epigenetic parameters of the serotonin transporter gene in obsessive-compulsive disorder

scientific article published on 16 October 2017

Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study

scientific article published on 13 August 2014

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

scientific article published on 7 June 2021

Commonalities in the genetics of Alzheimer's disease and Parkinson's disease

scientific article published on December 2008

Comparison analysis of gene expression patterns between sporadic Alzheimer's and Parkinson's disease

scientific article published on December 2007

Consensus paper of the WFSBP Task Force on Biological Markers of Dementia: the role of CSF and blood analysis in the early and differential diagnosis of dementia.

scientific article

Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia, part III: Molecular mechanisms

scientific article published on 26 October 2016

Contribution of Intracellular Non-Haem Iron, NF-kB Activation and Inflammatory Responses to Neurodegeneration in Parkinson’s Disease: Prospects for Neuroprotection

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Controversial Effects of D-Amino Acid Oxidase Activator (DAOA)/G72 on D-Amino Acid Oxidase (DAO) Activity in Human Neuronal, Astrocyte and Kidney Cell Lines: The N-methyl D-aspartate (NMDA) Receptor Hypofunction Point of View

scientific article

Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study

scientific article

Correction: Methylphenidate enhances neural stem cell differentiation

scientific article published on 10 June 2013

Correlation of cognitive deficits and brain cholinesterase activity in streptozotocin-intracerebroventricularly treated rat model of sporadic alzheimer's disease

scholarly article by Melita Salkovic Petrisic et al published July 2011 in Alzheimer's and Dementia

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.

scientific article

DNA methylation profiles of elderly individuals subjected to indentured childhood labor and trauma

scientific article

Determination of Monoamine Oxidase A and B Activity in Long-Term Treated Patients With Parkinson Disease

scientific article

Diabetes type II: a risk factor for depression-Parkinson-Alzheimer?

scientific article published on 15 June 2010

Different effects of soluble and aggregated amyloid β42 on gene/protein expression and enzyme activity involved in insulin and APP pathways

scientific article

Differential Alterations in Metabolism and Proteolysis-Related Proteins in Human Parkinson's Disease Substantia Nigra

scientific article published on 7 December 2017

Disorder-specific effects of polymorphisms at opposing ends of the Insulin Degrading Enzyme gene

scientific article

Early and late gene changes in MPTP mice model of Parkinson's disease employing cDNA microarray

scientific article published in October 2002

Early and late molecular events in neurodegeneration and neuroprotection in Parkinson's disease MPTP model as assessed by cDNA microarray; the role of iron

scientific article published on November 2002

Early impairment in dopaminergic neurotransmission in brains of SIV-infected rhesus monkeys due to microglia activation

scientific article published on 31 August 2005

Effects of R- and S-apomorphine on MPTP-induced nigro-striatal dopamine neuronal loss

scientific article

Effects of R- and S-apomorphine on MPTP-induced nigro-striatal dopamine neuronal loss

scholarly article by Edna Grünblatt et al published 28 June 2008 in Journal of Neurochemistry

Effects of methylphenidate: the cellular point of view

scientific article published on 10 November 2010

Effects of oxytocin and arginine vasopressin on the proliferation and differentiation of a serotonergic cell line.

scientific article

Emerging role of miRNA in attention deficit hyperactivity disorder: a systematic review

scientific article published on 10 May 2017

Enhancement of cell viability after treatment with polyunsaturated fatty acids

scientific article published on 21 November 2013

Epigenetic mechanisms in schizophrenia and other psychotic disorders: a systematic review of empirical human findings

scientific article published on 06 January 2020

Estrogen receptor beta gene (ESRbeta) 3'-UTR variants in Alzheimer disease.

scientific article

Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort

scientific article

Expression of D-Amino Acid Oxidase (DAO/DAAO) and D-Amino Acid Oxidase Activator (DAOA/G72) during Development and Aging in the Human Post-mortem Brain.

scientific article

Extraordinarily Fast Response to Low-Dose Sertraline in a Child with Severe Obsessive-Compulsive Disorder and High Functioning Serotonin Transporter Genotype

scholarly article by Edna Grünblatt et al published March 2014 in Journal of Child and Adolescent Psychopharmacology

From attention-deficit hyperactivity disorder to sporadic Alzheimer’s disease—Wnt/mTOR pathways hypothesis

scientific article published in 2023

Gene expression alterations in brain areas of intracerebroventricular streptozotocin treated rat.

scientific article published in August 2006

Gene expression analysis in N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice model of Parkinson's disease using cDNA microarray: effect of R-apomorphine

scientific article

Gene expression as peripheral biomarkers for sporadic Alzheimer's disease

scientific article published in January 2009

Gene expression profile in streptozotocin rat model for sporadic Alzheimer's disease

scientific article published on 13 August 2003

Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes

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Genes and Oxidative Stress in Sporadic and Familial Parkinsonism: cDNA Microarray Studies

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Genes and oxidative stress in parkinsonism: cDNA microarray studies.

scientific article

Genetic risk factors and markers for Alzheimer's disease and/or depression in the VITA study

scientific article published on 7 July 2008

Genetic variation in the choline O-acetyltransferase gene in depression and Alzheimer's disease: the VITA and Milano studies

scientific article

Genomic aspects of sporadic Parkinson's disease

scientific article published on 27 June 2008

Glucocorticoid receptor gene variants and lower expression of NR3C1 are associated with cocaine use

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Guidelines for the standardized collection of blood-based biomarkers in psychiatry: Steps for laboratory validity - a consensus of the Biomarkers Task Force from the WFSBP

scientific article published on 25 March 2019

HIV Dementia: A Neurodegenerative Disorder with Viral Etiology

article

High resolution chromosomal microarray analysis in paediatric obsessive-compulsive disorder

scientific article published on 28 November 2017

High-resolution chromosomal microarray analysis for copy-number variations in high-functioning autism reveals large aberration typical for intellectual disability

scientific article published on 14 December 2019

Imaging genetics in obsessive-compulsive disorder: linking genetic variations to alterations in neuroimaging

scientific article

Improved Generation of Induced Pluripotent Stem Cells From Hair Derived Keratinocytes - A Tool to Study Neurodevelopmental Disorders as ADHD

scientific article published on 25 September 2018

In vitro study methodologies to investigate genetic aspects and effects of drugs used in attention-deficit hyperactivity disorder

scientific article published on 26 July 2012

Increased activity of mitochondrial aldehyde dehydrogenase (ALDH) in the putamen of individuals with Alzheimer's disease: a human postmortem study

scientific article published in January 2010

Increased xanthine oxidase in the thalamus and putamen in depression

scientific article published in March 2010

Inflammatory Pathways in Parkinson's Disease; A BNE Microarray Study

scientific article published on 2 April 2012

Influence of oxytocin receptor single nucleotide sequence variants on contractility of human myometrium: an in vitro functional study

scientific article published on 12 November 2019

Integrating evolutionary and regulatory information with a multispecies approach implicates genes and pathways in obsessive-compulsive disorder

scientific article published on 17 October 2017

Investigation of association of serotonin transporter and monoamine oxidase-A genes with Alzheimer's disease and depression in the VITA study cohort: a 90-month longitudinal study

scientific article published on 17 January 2014

Iron chelating, antioxidant and cytoprotective properties of dopamine receptor agonist; apomorphine

scientific article

Iron in brain function and neurodegenerative disorders. Editorial

scientific article published in March 2011

Is the treatment with psychostimulants in children and adolescents with attention deficit hyperactivity disorder harmful for the dopaminergic system?

scientific article published on 21 April 2013

Manifesto for a European research network into Problematic Usage of the Internet

scientific article published on 10 October 2018

Manifesto for a European research network into obsessive-compulsive and related disorders ⬇️

scientific article published on July 15, 2012

Methyl- and acetyltransferases are stable epigenetic markers postmortem

scientific article

Methylphenidate enhances neural stem cell differentiation

scientific article published on 23 April 2013

Methylphenidate enhances neuronal differentiation and reduces proliferation concomitant to activation of Wnt signal transduction pathways

scientific article published in March 2018

Microarray analysis reveals distinct gene expression patterns in the mouse cortex following chronic neuroleptic and stimulant treatment: implications for body weight changes

scientific article published on 9 February 2006

Modeling sporadic Alzheimer's disease: the insulin resistant brain state generates multiple long-term morphobiological abnormalities including hyperphosphorylated tau protein and amyloid-beta

scientific article published on January 2009

Monoamine oxidase-B inhibition in Alzheimer's disease

scientific article published on January 2004

Neuregulin 1 (NRG1) gene expression predicts functional outcomes in individuals at clinical high-risk for psychosis

article

Neuregulin-1, D-amino acid oxidase and D-amino acid oxidase activator polymorphisms in individuals at-risk for psychosis

Neurochemical markers as potential indicators of postmortem tissue quality

scientific article published on 01 January 2018

Neurodegenerative diseases as well as psychiatric disorders

scientific article published in January 2013

Neuron-specific alterations in signal transduction pathways associated with Alzheimer's disease

scientific article

Neuron-specific mitochondrial DNA deletion levels in sporadic Alzheimer's disease

scientific article

Neuroprotective strategies in Parkinson's disease : an update on progress

scientific article

Neurotrophin blood-based gene expression and social cognition analysis in patients with autism spectrum disorder

scientific article published on 24 December 2014

New insights and perspectives on the genetics of obsessive-compulsive disorder

scientific article published on 01 October 2019

New insights into the genetic etiology of Alzheimer's disease and related dementias

scientific article published in April 2022

Nine-month follow-up of the insulin receptor signalling cascade in the brain of streptozotocin rat model of sporadic Alzheimer's disease

scientific article published on 12 December 2014

No Association of Variants of the NPY-System With Obsessive-Compulsive Disorder in Children and Adolescents

scientific article published on 03 May 2019

Oxidative stress related markers in the "VITA" and the centenarian projects

scientific article published in April 2005

P.1.g.071 Interaction between serotonin 1A and 2A receptor subtypes in neuronal and lymphoblastoid cells

scholarly article by Z. Marinova et al published October 2014 in European Neuropsychopharmacology

PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease

scientific article

Parkinson's disease: Molecular risk factors ⬇️

scientific article published on January 1, 2012

Pilot study on HTR2A promoter polymorphism, −1438G/A (rs6311) and a nearby copy number variation showed association with onset and severity in early onset obsessive–compulsive disorder

Pilot study: peripheral biomarkers for diagnosing sporadic Parkinson’s disease

scientific article published on 11 November 2010

Pilot study: potential transcription markers for adult attention-deficit hyperactivity disorder in whole blood

scientific article published on 06 May 2012

Potent neuroprotective and antioxidant activity of apomorphine in MPTP and 6-hydroxydopamine induced neurotoxicity

scientific article

Potential gene expression biomarkers in whole blood of Alzheimer's disease

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Preclinical versus clinical neuroprotection.

scientific article

Prediction Analysis for Transition to Schizophrenia in Individuals at Clinical High Risk for Psychosis: The Relationship of DAO, DAOA, and NRG1 Variants with Negative Symptoms and Cognitive Deficits

scientific article published on 20 December 2017

Prenatal stress increases the striatal and hippocampal expression of correlating c-FOS and serotonin transporters in murine offspring

scientific article published on 4 August 2014

Profiling parvalbumin interneurons using iPSC: challenges and perspectives for Autism Spectrum Disorder (ASD)

scientific article published on 29 January 2020

Psychiatric symptoms and expression of glucocorticoid receptor gene in cocaine users: A longitudinal study

scientific article published on 27 November 2019

REGION-SPECIFIC REGULATION OF THE SEROTONIN 2A RECEPTOR EXPRESSION IN DEVELOPMENT AND AGING IN POSTMORTEM HUMAN BRAIN

article

Rare copy number variants in individuals at clinical high risk for psychosis: Enrichment of synaptic/brain-related functional pathways

scientific article published on 19 November 2019

Real-time impedance-based cell analyzer as a tool to delineate molecular pathways involved in neurotoxicity and neuroprotection in a neuronal cell line.

scientific article

Region-specific regulation of the serotonin 2A receptor expression in development and ageing in post mortem human brain.

scientific article published in June 2015

S.08.01 Potential biomarkers and genetic findings in ADHD

S.08.03 New findings of copy number variations in OCD

Selection of novel reference genes for use in the human central nervous system: a BrainNet Europe Study

scientific article published on 5 August 2012

Simultaneous determination of MAO-A and -B activity following first time intake of an irreversible MAO-B inhibitor in patients with Parkinson's disease

scientific article published on 15 March 2017

The Pivotal Role of Iron in NF-kappaB Activation and Nigrostriatal Dopaminergic Neurodegeneration: Prospects for Neuroprotection in Parkinson's Disease with Iron Chelators

scientific article published on 01 January 1999

The benefits of microarrays as tools for studying neuropsychiatric disorders.

scientific article published on February 2004

The copper chelator, D-penicillamine, does not attenuate MPTP induced dopamine depletion in mice

scientific article

The diabetic brain and cognition

scientific article published on August 2017

The hallucinogen 2,5-dimethoxy-4-iodoamphetamine hydrochloride activates neurotrophin receptors in a neuronal cell line and promotes neurites extension

scientific article published on 18 March 2017

The impact of methylphenidate and its enantiomers on dopamine synthesis and metabolism in vitro

scientific article

The involvement of the canonical Wnt-signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta-analysis

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The link between iron, metabolic syndrome, and Alzheimer's disease

scientific article published on 17 June 2010

The loudness dependence of auditory evoked potentials (LDAEP) as an indicator of serotonergic dysfunction in patients with predominant schizophrenic negative symptoms

scientific article

The neurobiological link between OCD and ADHD

scientific article

The stress-Wnt-signaling axis: a hypothesis for attention-deficit hyperactivity disorder and therapy approaches

scientific article published on 18 September 2020

Trabalho de consenso de força-tarefa da WFSBP sobre marcadores biológicos das demências: contribuição da análise do LCR e do sangue para o diagnóstico precoce e diferencial das demências

Transcriptional alterations under continuous or pulsatile dopaminergic treatment in dyskinetic rats

scientific article published on 25 December 2010

Trio study and meta-analysis support the association of genetic variation at the serotonin transporter with early-onset obsessive-compulsive disorder

scientific article

Tryptophan is a marker of human postmortem brain tissue quality.

scientific article published on 22 June 2009

Wie biologisch sind Zwangsstörungen?

cDNA microarray to study gene expression of dopaminergic neurodegeneration and neuroprotection in MPTP and 6-hydroxydopamine models: implications for idiopathic Parkinson's disease

article

d/l threo-methylphenidate enantiomers influence on catecholaminergic enzyme activities

pH measurement as quality control on human post mortem brain tissue: a study of the BrainNet Europe consortium.

scientific article

α2A -Adrenergic receptor polymorphisms and mRNA expression levels are associated with delay discounting in cocaine users

scientific article published on 8 November 2015

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