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List of works by Georgy Bakalkin

A novel neuron-specific DNA end-binding factor in the murine brain

scientific article

A novel soluble protein factor with non-opioid dynorphin A-binding activity.

scientific article published on August 2004

Activation of NF-κB in Synovium versus Cartilage from Patients with Advanced Knee Osteoarthritis: A Potential Contributor to Inflammatory Aspects of Disease Progression

scholarly article by Aisha S Ahmed et al published 22 August 2018 in Journal of Immunology

Alcohol-induced plasticity in the dynorphin/kappa-opioid receptor system

scientific article

Amino acid sequence pattern in the regulatory peptides.

scientific article published in December 1991

Association of Protein Phosphatase PPM1G With Alcohol Use Disorder and Brain Activity During Behavioral Control in a Genome-Wide Methylation Analysis

scientific article published on 18 May 2015

Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states

scientific article published on 29 October 2012

Asymmetry of the endogenous opioid system in the human anterior cingulate: a putative molecular basis for lateralization of emotions and pain

scientific article

Attenuation of pain and inflammation in adjuvant-induced arthritis by the proteasome inhibitor MG132.

scientific article published in July 2010

Autoantigen Ku in the brain. Developmentally regulated expression and subcellular localization

scientific journal article

BLOTTO-MF, an inexpensive and reliable hybridization solution in northern blot analysis using complementary RNA probes

Big dynorphin as a putative endogenous ligand for the kappa-opioid receptor

scientific article

Big dynorphin, a prodynorphin-derived peptide produces NMDA receptor-mediated effects on memory, anxiolytic-like and locomotor behavior in mice

scientific article

Calcium influx into phospholipid vesicles caused by dynorphin neuropeptides

scientific article published on 21 February 2008

Cardiotropic effects of luliberin. Effects of luliberin on the activities of phosphorylase A and ornithine decarboxylase and concentration of 3', 5'-AMP

scientific article published on February 1979

Cardiotropic effects of luliberin. Interaction with rat heart sarcolemmal membrane

scientific article published on March 1979

Caspase-3 activity is reduced after spinal cord injury in mice lacking dynorphin: differential effects on glia and neurons.

scientific article

Changes in mitochondrial heterogenicity during aerobic growth of Saccharomyces cerevisiae yeasts

scientific article

Clustering of apoptotic cells via bystander killing by peroxides

scientific article published in September 2000

Conformation effects of CpG methylation on single-stranded DNA oligonucleotides: analysis of the opioid peptide dynorphin-coding sequences

scientific article

Control of chronic pain by the ubiquitin proteasome system in the spinal cord.

scientific article published on August 2007

Cytotoxic effects of dynorphins through nonopioid intracellular mechanisms

scientific article published in September 2001

Decoy peptides that bind dynorphin noncovalently prevent NMDA receptor-mediated neurotoxicity

scientific article

Degradation of total cell protein at different stages of Saccharomyces cerevisiae yeast growth

scientific article

Denaturation of dsDNA by p53: fluorescence correlation spectroscopy study

scientific article published in April 2004

Dimethyl-labeling-based protein quantification and pathway search: a novel method of spinal cord analysis applicable for neurological studies

scientific article

Dopamine D1 receptors have subcellular distributions conducive to interactions with prodynorphin in the rat nucleus accumbens shell

scientific article published in July 2006

Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholics

scientific article published on 12 May 2015

Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics.

scientific article

Dynorphin A (1-17) induces apoptosis in striatal neurons in vitro through alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor-mediated cytochrome c release and caspase-3 activation

scientific article published on January 2003

Dysregulation of cell death machinery in the prefrontal cortex of human alcoholics.

scientific article

Dysregulation of dynorphins in Alzheimer disease

scientific article published on 17 August 2006

Effect of luliberin on the activities of mitochondrial respiratory enzymes

scientific article published on August 1979

Effects of the circadian rhythm gene period 1 (per1) on psychosocial stress-induced alcohol drinking

scientific article published on 9 August 2011

Elevated mutant dynorphin A causes Purkinje cell loss and motor dysfunction in spinocerebellar ataxia type 23.

scientific article published on 12 July 2015

Elevated synaptophysin I in the prefrontal cortex of human chronic alcoholics

scientific article

Endogenous opioids and oligodendroglial function: possible autocrine/paracrine effects on cell survival and development

scientific article published in August 2001

Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

scientific article published on 06 December 2019

Expression of pronociceptin and its receptor is downregulated in the brain of human alcoholics

scientific article

Expression of specific ionotropic glutamate and GABA-A receptor subunits is decreased in central amygdala of alcoholics

scientific article

FOSB proteins in the orbitofrontal and dorsolateral prefrontal cortices of human alcoholics

scientific article

Fluorescence Imaging with Single-Molecule Sensitivity and Fluorescence Correlation Spectroscopy of Cell-Penetrating Neuropeptides

GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics

scientific article

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

scientific journal article

IGF-II enhances trichostatin A-induced TGFbeta1 and p21(Waf1,Cip1, sdi1) expression in Hep3B cells

scientific article published in December 1999

Identification and characterization of novel PDYN mutations in dominant cerebellar ataxia cases.

scientific article published on 8 March 2013

Immunoreactive luliberin in the visceral organs of rats

scientific article

Intra- and interregional coregulation of opioid genes: broken symmetry in spinal circuits

scientific article

Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-D-aspartate receptor mechanism

scientific article

Involvement of the p53 tumor-suppressor protein in the development of antinociceptive tolerance to morphine

scientific article

LUMA (LUminometric Methylation Assay)--a high throughput method to the analysis of genomic DNA methylation.

scientific article published on 19 April 2006

Lateralized response of dynorphin a peptide levels after traumatic brain injury

scientific article

Long-term morphine treatment increases Ku protein DNA end-binding activity

Membrane leakage induced by dynorphins

scholarly article by Loïc Hugonin published in May 2006

Methylation of OPRL1 mediates the effect of psychosocial stress on binge drinking in adolescents

scientific article

Molecular mechanism for opioid dichotomy: bidirectional effect of μ-opioid receptors on P2X₃ receptor currents in rat sensory neurones.

scientific article

Morphine exacerbates HIV-1 Tat-induced cytokine production in astrocytes through convergent effects on [Ca(2+)](i), NF-kappaB trafficking and transcription

scientific article

Mu opioid receptor A118G polymorphism in association with striatal opioid neuropeptide gene expression in heroin abusers

scholarly article

Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system.

scientific article

Neuropeptide imaging in rat spinal cord with MALDI-TOF MS: Method development for the application in pain-related disease studies

scientific article

Neuropeptides: the history of their study and the prospects for their use in medicine

scientific article published on 01 January 1981

Nociceptive behavior induced by poly-L-lysine and other basic compounds involves the spinal NMDA receptors

scientific article published in May 2004

Nociceptive behavior induced by the endogenous opioid peptides dynorphins in uninjured mice: evidence with intrathecal N-ethylmaleimide inhibiting dynorphin degradation

scientific article published on January 2009

Non-opioid nociceptive activity of human dynorphin mutants that cause neurodegenerative disorder spinocerebellar ataxia type 23.

scientific article

Opioids modulate cell division in the germinal zone of the late embryonic neocortex

scientific article published in August 1999

PDYN rs2281285 variant association with drinking to avoid emotional or somatic discomfort

scientific article

PDYN, a gene implicated in brain/mental disorders, is targeted by REST in the adult human brain

scientific article

Pathobiology of dynorphins in trauma and disease

scientific article

Perturbations of model membranes induced by pathogenic dynorphin A mutants causing neurodegeneration in human brain

scientific article published on 25 June 2011

Plasma membrane poration by opioid neuropeptides: a possible mechanism of pathological signal transduction.

scientific article published on 12 March 2015

Prodynorphin CpG-SNPs associated with alcohol dependence: elevated methylation in the brain of human alcoholics

scientific article

Prodynorphin Mutations Cause the Neurodegenerative Disorder Spinocerebellar Ataxia Type 23.

scientific article published in November 2010

Prodynorphin gene expression relates to NF-kappa B factors

scientific article published on July 1994

Prodynorphin knockout mice demonstrate diminished age-associated impairment in spatial water maze performance

scientific article

Prodynorphin mutations cause the neurodegenerative disorder spinocerebellar ataxia type 23.

scientific article

Prodynorphin promoter SNP associated with alcohol dependence forms noncanonical AP-1 binding site that may influence gene expression in human brain

scientific article published on 19 February 2011

Prodynorphin storage and processing in axon terminals and dendrites

scientific article

Prodynorphin transcripts and proteins differentially expressed and regulated in the adult human brain.

scientific article published on 12 July 2005

Pronociceptive role of dynorphins in uninjured animals: N-ethylmaleimide-induced nociceptive behavior mediated through inhibition of dynorphin degradation.

scientific article published in February 2005

Proteasome inhibitor MG132 modulates inflammatory pain by central mechanisms in adjuvant arthritis

Proteomics of neuropathic pain: proteins and signaling pathways affected in a rat model

scientific article

Relationship between the pineal body and the hypothalamo-hypophyseal complex. 3. Possible role of LH releasing hormone in the hypothalamo-epiphyseal feedback

scientific article

Repeated exposure to moderate doses of ethanol augments hippocampal glutamate neurotransmission by increasing release

scientific article published on 23 December 2010

Repeated moderate-dose ethanol bouts impair cognitive function in Wistar rats

scientific article published on 26 October 2011

Selective Changes of GABA(A) Channel Subunit mRNAs in the Hippocampus and Orbitofrontal Cortex but not in Prefrontal Cortex of Human Alcoholics

scientific article published on January 2011

Selective increases of AMPA, NMDA, and kainate receptor subunit mRNAs in the hippocampus and orbitofrontal cortex but not in prefrontal cortex of human alcoholics

scientific article published on 29 January 2014

Study of molecular events in cells by fluorescence correlation spectroscopy.

scientific article

Substrate specificity of peptidases catalyzing LH-RH degradation in hypothalamus, liver and heart of rat

scientific article published on January 1979

Suppression of pain and joint destruction by inhibition of the proteasome system in experimental osteoarthritis.

scientific article

Targeting dynorphin/kappa opioid receptor systems to treat alcohol abuse and dependence

scientific article

The Cortical Neuroimmune Regulator TANK Affects Emotional Processing and Enhances Alcohol Drinking: A Translational Study

scientific article published on 01 April 2019

The Leu-enkephalin-encoding sequence DNA-binding factor (LEF) is the transcription factor YY1.

scientific article published on February 1997

The endogenous opioid system in human alcoholics: molecular adaptations in brain areas involved in cognitive control of addiction

scientific article

The lability of the products of mitochondrial protein synthesis in Saccharomyces cerevisiae. A novel method for protein half-life determination

scientific article

The nociceptin/orphanin FQ receptor agonist Ro 64-6198 reduces alcohol self-administration and prevents relapse-like alcohol drinking

scientific article

The single-stranded DNA end binding site of p53 coincides with the C-terminal regulatory region.

scientific article

Transcriptional control of maladaptive and protective responses in alcoholics: a role of the NF-κB system

scientific article published on 30 December 2010

Translocation of dynorphin neuropeptides across the plasma membrane. A putative mechanism of signal transmission

scientific article

Upregulated dynorphin opioid peptides mediate alcohol-induced learning and memory impairment

scientific article published on 08 October 2013

Validation of endogenous controls for quantitative gene expression analysis: application on brain cortices of human chronic alcoholics

scientific article published on 26 December 2006

YY1 binding to a subset of p53 DNA-target sites regulates p53-dependent transcription.

scientific article

[Asymmetrical distribution of luliberin in the rat hypothalamus]

scientific article published on 01 January 1983

[Characteristics of the development of postural asymmetry in rats as affected by the opioids met-enkephalin and the kappa-agonist bremazocine]

scientific article published on 01 November 1987

[Development of positional asymmetry during pain, immobilization, and cold stress]

scientific article published on 01 January 1980

[Differences in opioid binding in the left and right visual cortex of the turtle]

article

[Enkephalin inhibition of the electrical activity of the visual cortex of the left and right hemispheres]

scientific article published on 01 January 1981

[Leu5]enkephalin-encoding sequences are targets for a specific DNA-binding factor

scientific article

[Postural asymmetry induction by factors of the right and left hemispheres]

scientific article published on 01 January 1981

[Preferential development of flexion of the left or right hindlimb as a result of treatment with methionine-enkephalin or leucine-enkephalin, respectively]

scientific article published on 01 January 1980

[Problems of the synthesis and study of neurohormones]

scientific article published on 01 January 1980

[The opiate sigma-agonist SKF 10.047 disturbs the early morphogenesis of the loach]

scientific article published on 01 January 1986

p53 Latency. C-terminal domain prevents binding of p53 core to target but not to nonspecific DNA sequences.

scientific article

p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

scientific article

p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain

scientific article

p53 latency – out of the blind alley

scientific article published on 01 December 2002

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