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List of works by Jarogniew Łuszczki

1-Methyl-1,2,3,4-tetrahydroisoquinoline enhances the anticonvulsant action of carbamazepine and valproate in the mouse maximal electroshock seizure model

scientific article

2-Chloro-N6-cyclopentyladenosine enhances the anticonvulsant action of carbamazepine in the mouse maximal electroshock-induced seizure model.

scientific article published in November 2005

2-Chloroadenosine, a preferential agonist of adenosine A1 receptors, enhances the anticonvulsant activity of carbamazepine and clonazepam in mice

scientific article published in April 2002

2-Methyl-6-phenylethynyl-pyridine (MPEP), a non-competitive mGluR5 antagonist, differentially affects the anticonvulsant activity of four conventional antiepileptic drugs against amygdala-kindled seizures in rats

scientific article published in July 2009

2-phosphonomethyl-pentanedioic acid (glutamate carboxypeptidase II inhibitor) increases threshold for electroconvulsions and enhances the antiseizure action of valproate against maximal electroshock-induced seizures in mice

scientific article published on 3 January 2006

7-Nitroindazole enhances dose-dependently the anticonvulsant activities of conventional antiepileptic drugs in the mouse maximal electroshock-induced seizure model.

scientific article published in September 2006

7-Nitroindazole potentiates the anticonvulsant action of some second-generation antiepileptic drugs in the mouse maximal electroshock-induced seizure model

scientific article published on 9 February 2006

7-Nitroindazole, a nitric oxide synthase inhibitor, enhances the anticonvulsive action of ethosuximide and clonazepam against pentylenetetrazol-induced convulsions

scientific article published in January 2000

7-Nitroindazole, but not NG-nitro-L-arginine, enhances the anticonvulsant activity of pregabalin in the mouse maximal electroshock-induced seizure model.

scientific article published in January 2011

A Long-Term Treatment with Arachidonyl-2'-Chloroethylamide Combined with Valproate Increases Neurogenesis in a Mouse Pilocarpine Model of Epilepsy

scientific article

ACEA (a highly selective cannabinoid CB1 receptor agonist) stimulates hippocampal neurogenesis in mice treated with antiepileptic drugs

scientific article published on 27 July 2015

Acute and chronic treatment with mianserin differentially affects the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock model

scientific article

Acute exposure to caffeine decreases the anticonvulsant action of ethosuximide, but not that of clonazepam, phenobarbital and valproate against pentetrazole-induced seizures in mice.

scientific article published in September 2006

Additive Interaction of Cisplatin and Histone Deacetylase Inhibitors Combined Treatment in Rhabdomyosarcoma Cells - An Isobolographic Analysis.

scientific article published on March 2017

Additive Interactions between 1-Methyl-1,2,3,4-Tetrahydroisoquinoline and Clobazam in the Mouse Maximal Electroshock-Induced Tonic Seizure Model - An Isobolographic Analysis for Parallel Dose-Response Relationship Curves

scientific article published on 13 May 2014

Additive Pharmacological Interaction between Cisplatin (CDDP) and Histone Deacetylase Inhibitors (HDIs) in MDA-MB-231 Triple Negative Breast Cancer (TNBC) Cells with Altered Notch1 Activity-An Isobolographic Analysis

scientific article published on 26 July 2019

Additive interactions of pregabalin with lamotrigine, oxcarbazepine and topiramate in the mouse maximal electroshock-induced seizure model: a type I isobolographic analysis for non-parallel dose-response relationship curves

scientific article published on 6 August 2010

Agmatine enhances the anticonvulsant action of phenobarbital and valproate in the mouse maximal electroshock seizure model

scientific article published in April 2008

Allopurinol does not affect the anticonvulsant activity of carbamazepine and valproate in maximal electroshock-induced convulsions in mice.

scientific article published in January 2004

Amiloride enhances the anticonvulsant action of various antiepileptic drugs in the mouse maximal electroshock seizure model.

scientific article published on 22 November 2008

Analysis of new potential anticonvulsant compounds in mice brain tissue by SPE/HPLC/DAD.

scientific article

Anticonvulsant Effectiveness and Neurotoxicity Profile of 4-butyl-5-[(4-chloro-2-methylphenoxy)methyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione (TPL-16) in Mice

scientific article published on 18 November 2020

Anticonvulsant and acute adverse effect profiles of picolinic acid 2-fluoro-benzylamide in various experimental seizure models and chimney test in mice

scientific article published on 15 November 2007

Anticonvulsant and acute neurotoxic characteristics of nicotinic acid benzylamide: a preclinical study

scientific article published on 01 May 2006

Anticonvulsant and acute neurotoxic effects of imperatorin, osthole and valproate in the maximal electroshock seizure and chimney tests in mice: a comparative study.

scientific article published on 29 April 2009

Anticonvulsant and neurotoxic effects of a novel 1,2,4-triazole-3-thione derivative (TPF-34) and its isobolographic interaction profile with classical antiepileptic drugs in mice

scientific article published on 20 December 2019

Anticonvulsant effects of four linear furanocoumarins, bergapten, imperatorin, oxypeucedanin, and xanthotoxin, in the mouse maximal electroshock-induced seizure model: a comparative study

scientific article published on November 2010

Anticonvulsant profile of caprylic acid, a main constituent of the medium-chain triglyceride (MCT) ketogenic diet, in mice.

scientific article

Arachidonyl-2'-chloroethylamide, a highly selective cannabinoid CB1 receptor agonist, enhances the anticonvulsant action of valproate in the mouse maximal electroshock-induced seizure model

scientific article published on 27 July 2006

Arvanil, olvanil, AM 1172 and LY 2183240 (various cannabinoid CB1 receptor agonists) increase the threshold for maximal electroshock-induced seizures in mice

scientific article published on 24 August 2017

Assessment of Interactions between Cisplatin and Two Histone Deacetylase Inhibitors in MCF7, T47D and MDA-MB-231 Human Breast Cancer Cell Lines - An Isobolographic Analysis

scientific article published on 18 November 2015

Assessment of the Combined Treatment with Umbelliferone and Four Classical Antiepileptic Drugs Against Maximal Electroshock-Induced Seizures in Mice

scientific article published in 2015

Assessment of the anticonvulsant potency of various benzylamide derivatives in the mouse maximal electroshock-induced seizure threshold model

scientific article published on 25 September 2015

Beneficial Combination of Lacosamide with Retigabine in Experimental Animals: An Isobolographic Analysis.

scientific article

Biphasic characteristic of interactions between stiripentol and carbamazepine in the mouse maximal electroshock-induced seizure model: a three-dimensional isobolographic analysis

scientific article published on 14 September 2006

Characterization and preliminary anticonvulsant assessment of some 1,3,4-thiadiazole derivatives.

scientific article published on 24 December 2014

Characterization of acute adverse-effect profiles of selected antiepileptic drugs in the grip-strength test in mice

scientific article published in July 2009

Characterization of the anticonvulsant profile of isonicotinic acid benzylamide in various experimental seizure models in mice

scientific article published on 24 May 2007

Characterization of the anticonvulsant, behavioral and pharmacokinetic interaction profiles of stiripentol in combination with clonazepam, ethosuximide, phenobarbital, and valproate using isobolographic analysis

scientific article published in November 2006

Cholecalciferol enhances the anticonvulsant effect of conventional antiepileptic drugs in the mouse model of maximal electroshock

scientific article

Chronically administered fluoxetine enhances the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock model

scientific article

Clinical utility of adjunctive retigabine in partial onset seizures in adults.

scientific article published on 20 January 2012

Combination of Osthole and Cisplatin Against Rhabdomyosarcoma TE671 Cells Yielded Additive Pharmacologic Interaction by Means of Isobolographic Analysis

scientific article published in January 2018

Combination of phenobarbital with phenytoin and pregabalin produces synergy in the mouse tonic-clonic seizure model: An isobolographic analysis

scientific article published on 18 June 2018

Comparison of mouse plasma and brain tissue homogenate sample pretreatment methods prior to high-performance liquid chromatography for a new 1,2,4-triazole derivative with anticonvulsant activity.

scientific article published on 7 May 2015

Comparison of the anticonvulsant potency of various diuretic drugs in the maximal electroshock-induced seizure threshold test in mice.

scientific article published on 20 March 2018

Correction to: Long-term vigabatrin treatment modifies pentylenetetrazole-induced seizures in mice: focused on GABA brain concentration

scientific article published on 01 April 2020

Corrigendum to “Influence of caffeine on the protective activity of gabapentin and topiramate in a mouse model of generalized tonic-clonic seizures” [Pharmacol. Rep. 68 (2016) 680–685]

scientific article published on 06 February 2017

Cytisine inhibits the anticonvulsant activity of phenytoin and lamotrigine in mice

scientific article published on 01 January 2013

Cytisine inhibits the protective activity of various classical and novel antiepileptic drugs against 6 Hz-induced psychomotor seizures in mice

scientific article

Design, synthesis and biological evaluation of new hybrid anticonvulsants derived from N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide and 2-(2,5-dioxopyrrolidin-1-yl)butanamide derivatives

scientific article published on 21 March 2015

Design, synthesis, and anticonvulsant activity of new hybrid compounds derived from 2-(2,5-dioxopyrrolidin-1-yl)propanamides and 2-(2,5-dioxopyrrolidin-1-yl)butanamides

scientific article published on 23 June 2015

Development of the 1,2,4-triazole-based anticonvulsant drug candidates acting on the voltage-gated sodium channels. Insights from in-vivo, in-vitro, and in-silico studies

scientific article published on 28 December 2018

Dose-response relationship analysis of pregabalin doses and their antinociceptive effects in hot-plate test in mice

scientific article published on September 1, 2010

Dose-response relationship analysis of vigabatrin doses and their antinociceptive effects in the hot-plate test in mice

scientific article published in May 2008

Dronedarone (a multichannel blocker) enhances the anticonvulsant potency of lamotrigine, but not that of lacosamide, pregabalin and topiramate in the tonic-clonic seizure model in mice

scientific article published on 22 April 2019

Drug resistance in epilepsy

scientific article published in January 2009

Effect of 1-methyl-1,2,3,4-tetrahydroisoquinoline on the protective action of various antiepileptic drugs in the maximal electroshock-induced seizure model: a type II isobolographic analysis.

scientific article published on 07 June 2013

Effect of 4-(4-bromophenyl)-5-(3-chlorophenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione on the anticonvulsant action of different classical antiepileptic drugs in the mouse maximal electroshock-induced seizure model ⬇️

scientific article published on June 23, 2012

Effect of ACEA--a selective cannabinoid CB1 receptor agonist on the protective action of different antiepileptic drugs in the mouse pentylenetetrazole-induced seizure model

scientific article published on 10 July 2012

Effect of NG-nitro-L-arginine on the anticonvulsant action of four second-generation antiepileptic drugs in pentetrazole-induced clonic seizures in mice.

scientific article published in July 2007

Effect of acute and chronic treatment with milnacipran potentiates the anticonvulsant activity of conventional antiepileptic drugs in the maximal electroshock-induced seizures in mice

scientific article published on 20 October 2009

Effect of acutely and chronically administered venlafaxine on the anticonvulsant action of classical antiepileptic drugs in the mouse maximal electroshock model

scientific article published on 12 September 2011

Effect of arachidonyl-2'-chloroethylamide, a selective cannabinoid CB1 receptor agonist, on the protective action of the various antiepileptic drugs in the mouse maximal electroshock-induced seizure model

scientific article published on 13 September 2009

Effect of gabapentin on the anticonvulsant activity of antiepileptic drugs against electroconvulsions in mice: an isobolographic analysis.

scientific article published in September 2002

Effect of histamine receptor antagonists on aminophylline-induced seizures and lethality in mice.

scientific article published in July 2005

Effect of lamotrigine combined with felbamate on the horizontal (ambulatory) activity in mice.

scientific article

Effect of p-isopropoxyphenylsuccinimide monohydrate on the anticonvulsant action of carbamazepine, phenobarbital, phenytoin and valproate in the mouse maximal electroshock-induced seizure model

scientific article published in January 2010

Effect of sildenafil on the anticonvulsant action of classical and second-generation antiepileptic drugs in maximal electroshock-induced seizures in mice

scientific article published on 7 January 2010

Effect of topiramate on the anticonvulsant activity of conventional antiepileptic drugs in two models of experimental epilepsy

scientific article published in May 2003

Effect of xanthotoxin (8-methoxypsoralen) on the anticonvulsant activity of classical antiepileptic drugs against maximal electroshock-induced seizures in mice.

scientific article published on 28 May 2015

Effects of N-(morpholinomethyl)-p-isopropoxyphenylsuccinimide on the protective action of different classical antiepileptic drugs against maximal electroshock-induced tonic seizures in mice

scientific article

Effects of WIN 55,212-2 (a non-selective cannabinoid CB1 and CB 2 receptor agonist) on the protective action of various classical antiepileptic drugs in the mouse 6 Hz psychomotor seizure model

scientific article

Effects of WIN 55,212-2 (a synthetic cannabinoid CB1 and CB2 receptor agonist) on the anticonvulsant activity of various novel antiepileptic drugs against 6 Hz-induced psychomotor seizures in mice.

scientific article published on 13 January 2015

Effects of WIN 55,212-2 mesylate (a synthetic cannabinoid) on the protective action of clonazepam, ethosuximide, phenobarbital and valproate against pentylenetetrazole-induced clonic seizures in mice.

scientific article published on 18 July 2011

Effects of WIN 55,212-2 mesylate on the anticonvulsant action of lamotrigine, oxcarbazepine, pregabalin and topiramate against maximal electroshock-induced seizures in mice.

scientific article published on 23 October 2013

Effects of amlodipine, diltiazem, and verapamil on the anticonvulsant action of topiramate against maximal electroshock-induced seizures in mice

scientific article published in March 2008

Effects of androsterone on the protective action of various antiepileptic drugs against maximal electroshock-induced seizures in mice

scientific article published on 28 October 2018

Effects of arachidonyl-2'-chloroethylamide (ACEA) on the protective action of various antiepileptic drugs in the 6-Hz corneal stimulation model in mice.

scientific article published on 31 August 2017

Effects of some convulsant agents on the protective activity of topiramate against maximal electroshock-induced seizures in mice

scientific article published in May 2005

Effects of some new antiepileptic drugs and progabide on glucocorticoid receptor-mediated gene transcription in LMCAT cells.

scientific article published on September 2007

Effects of tamoxifen, mifepristone and cyproterone on the electroconvulsive threshold and pentetrazole-induced convulsions in mice.

scientific article

Effects of three N-(carboxyanilinomethyl) derivatives of p-isopropoxyphenylsuccinimide on the anticonvulsant action of carbamazepine, phenobarbital, phenytoin and valproate in the mouse maximal electroshock-induced seizure model.

scientific article

Effects of three calcium channel antagonists (amlodipine, diltiazem and verapamil) on the protective action of lamotrigine in the mouse maximal electroshock-induced seizure model

scientific article

Endocannabinoid system as a regulator of tumor cell malignancy - biological pathways and clinical significance

scientific article

Evaluation of interaction between gabapentin and baclofen in the formalin test in mice

scientific article

Evaluation of the impact of compound C11 a new anticonvulsant candidate on cognitive functions and hippocampal neurogenesis in mouse brain

scientific article published on 09 November 2019

Exploring the latest avenues for antiepileptic drug discovery and development

scientific article published on 29 February 2016

Furosemide potentiates the anticonvulsant action of valproate in the mouse maximal electroshock seizure model.

scientific article published on 30 July 2007

Gabapentin synergistically interacts with topiramate in the mouse maximal electroshock seizure model: an isobolographic analysis

scientific article

Gemcitabine and Selected mTOR Inhibitors in Uterine Sarcomas and Carcinosarcoma Cells- an Isobolographic Analysis

scientific article published on 18 October 2020

Histone Deacetylase Inhibitor SAHA as Potential Targeted Therapy Agent for Larynx Cancer Cells

scientific article published on January 2017

How significant is the difference between drug doses influencing the threshold for electroconvulsions?

scientific article published in November 2005

Imperatorin enhances the protective activity of conventional antiepileptic drugs against maximal electroshock-induced seizures in mice

scientific article

Indapamide enhances the protective action of carbamazepine, phenobarbital, and valproate against maximal electroshock-induced seizures in mice

scientific article

Influence of 5-(3-chlorophenyl)-4-(4-methylphenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione on the anticonvulsant action of 4 classical antiepileptic drugs in the mouse maximal electroshock-induced seizure model ⬇️

scientific article published on January 1, 2012

Influence of Ivabradine on the Anticonvulsant Action of Four Classical Antiepileptic Drugs Against Maximal Electroshock-Induced Seizures in Mice

scientific article published on 12 January 2017

Influence of LY 300164 alone or in combination with carbamazepine or diphenylhydantoin on the body temperature in mice.

scientific article

Influence of MPEP (a selective mGluR5 antagonist) on the anticonvulsant action of novel antiepileptic drugs against maximal electroshock-induced seizures in mice.

scientific article

Influence of N-hydroxymethyl-p-isopropoxyphenylsuccinimide on the anticonvulsant action of different classical antiepileptic drugs in the mouse maximal electroshock-induced seizure model.

scientific article published on 24 January 2012

Influence of NG-nitro-L-arginine on the anticonvulsant and acute adverse effects of some newer antiepileptic drugs in the maximal electroshock-induced seizures and chimney test in mice.

scientific article

Influence of SIB 1893, a selective mGluR5 receptor antagonist, on the anticonvulsant activity of conventional antiepileptic drugs in two models of experimental epilepsy.

scientific article published in September 2003

Influence of WIN 55,212-2 on the anticonvulsant and acute neurotoxic potential of clobazam and lacosamide in the maximal electroshock-induced seizure model and chimney test in mice

scientific article published on 17 October 2014

Influence of agmatine on the protective action of numerous antiepileptic drugs against pentetrazole-induced seizures in mice.

scientific article published in March 2009

Influence of aminophylline on the anticonvulsive action of gabapentin in the mouse maximal electroshock seizure threshold model

scientific article published on 24 August 2007

Influence of arachidonyl-2'-chloroethylamide, a selective cannabinoid CB1 receptor agonist, on the anticonvulsant and acute side-effect potentials of clobazam, lacosamide, and pregabalin in the maximal electroshock-induced seizure model and chimney

scientific article published on 12 May 2015

Influence of arachidonyl-2′-chloroethylamide (ACEA) on the anticonvulsant and acute neurotoxic effects of pregabalin in mice

Influence of caffeine on the protective activity of gabapentin and topiramate in a mouse model of generalized tonic-clonic seizures.

scientific article published on 26 March 2016

Influence of dronedarone (a class III antiarrhythmic drug) on the anticonvulsant potency of four classical antiepileptic drugs in the tonic-clonic seizure model in mice.

scientific article published on 8 December 2018

Influence of ethacrynic acid on the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock seizure model

scientific article published on September 2010

Influence of imperatorin on the anticonvulsant activity and acute adverse-effect profile of lamotrigine in maximal electroshock-induced seizures and chimney test in mice

scientific article

Influence of salbutamol on the anticonvulsant potency of the antiepileptic drugs in the maximal electroshock-induced seizures in mice

scientific article published on 08 February 2019

Influence of sexual hormone antagonists on the anticonvulsant action of conventional antiepileptic drugs against electrically- and pentylenetetrazol-induced seizures in mice.

scientific article

Influence of sildenafil on the anticonvulsant action of selected antiepileptic drugs against pentylenetetrazole-induced clonic seizures in mice.

scientific article

Influence of vigabatrin, a novel antiepileptic drug, on the anticonvulsant activity of conventional antiepileptics in pentetrazole-induced seizures in mice

scientific article published in May 2003

Influence of xanthotoxin (8-methoxypsoralen) on the anticonvulsant activity of various novel antiepileptic drugs against maximal electroshock-induced seizures in mice.

scientific article published in October 2016

Interaction between lamotrigine and felbamate in the maximal electroshock-induced seizures in mice: an isobolographic analysis

scientific article published in March 2005

Interaction of pregabalin with carbamazepine in the mouse maximal electroshock-induced seizure model: a type I isobolographic analysis for non-parallel dose-response relationship curves

scientific article published in January 2010

Interaction of tiagabine with valproate in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis for non-parallel dose-response relationship curves

scientific article

Interactions between non-barbiturate injectable anesthetics and conventional antiepileptic drugs in the maximal electroshock test in mice--an isobolographic analysis

scientific article published in March 2004

Interactions between oxcarbazepine and conventional antiepileptic drugs in the maximal electroshock test in mice: an isobolographic analysis

scientific article published in April 2003

Interactions between tiagabine and conventional antiepileptic drugs in the rat model of complex partial seizures

scientific article

Interactions between two enantiomers of losigamone and conventional antiepileptic drugs in the mouse maximal electroshock model--an isobolographic analysis

scientific article

Interactions between zonisamide and conventional antiepileptic drugs in the mouse maximal electroshock test model

scientific article published on 28 July 2006

Interactions of 1-methyl-1,2,3,4-tetrahydroisoquinoline with lamotrigine, oxcarbazepine, pregabalin, and topiramate in the mouse maximal electroshock-induced seizure model: a type I isobolographic analysis

scientific article published in February 2010

Interactions of 1-methyl-1,2,3,4-tetrahydroisoquinoline with the various antiepileptic drugs in the mouse maximal electroshock- induced seizure model

Interactions of MRZ 2/576 with felbamate, lamotrigine, oxcarbazepine and topiramate in the mouse maximal electroshock-induced seizure model

scientific article published on 4 February 2008

Interactions of lamotrigine with topiramate and first-generation antiepileptic drugs in the maximal electroshock test in mice: an isobolographic analysis.

scientific article published in August 2003

Interactions of levetiracetam with carbamazepine, phenytoin, topiramate and vigabatrin in the mouse 6Hz psychomotor seizure model - a type II isobolographic analysis

scientific article published on 7 November 2013

Interactions of pregabalin with gabapentin, levetiracetam, tiagabine and vigabatrin in the mouse maximal electroshock-induced seizure model: a type II isobolographic analysis

scientific article published on 25 September 2011

Interactions of stiripentol with clobazam and valproate in the mouse maximal electroshock-induced seizure model

scientific article published on 20 May 2010

Interactions of tiagabine with ethosuximide in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis for non-parallel dose-response relationship curves

scientific article published on 20 June 2008

Interactions of tiagabine with some antiepileptics in the maximal electroshock in mice.

scientific article published in May 2003

Is a hypothermic effect of LY300164, valproate and phenobarbital evident in mice?

scientific article published on 01 January 2004

Isobolographic Analysis Demonstrates the Additive and Synergistic Effects of Gemcitabine Combined with Fucoidan in Uterine Sarcomas and Carcinosarcoma Cells

scientific article published on 31 December 2019

Isobolographic Analysis of Interaction for Three-Drug Combination of Carbamazepine, Phenobarbital and Topiramate in the Mouse Maximal Electroshock-Induced Seizure Model

scientific article published on 25 February 2016

Isobolographic additivity among lacosamide, lamotrigine and phenobarbital in a mouse tonic-clonic seizure model

scientific article published on 01 July 2018

Isobolographic analysis demonstrates additive effect of cisplatin and HDIs combined treatment augmenting their anti-cancer activity in lung cancer cell lines.

scientific article published on December 2016

Isobolographic analysis of interaction between drugs with nonparallel dose-response relationship curves: a practical application

scientific article

Isobolographic analysis of interactions between 1-methyl-1,2,3,4-tetrahydroisoquinoline and four conventional antiepileptic drugs in the mouse maximal electroshock-induced seizure model

scientific article

Isobolographic analysis of interactions between loreclezole and conventional antiepileptic drugs in the mouse maximal electroshock-induced seizure model

scientific article published on 8 April 2006

Isobolographic analysis of interactions between losigamone and conventional antiepileptic drugs in the mouse maximal electroshock model

scientific article published on 6 March 2006

Isobolographic analysis of interactions between remacemide and conventional antiepileptic drugs in the mouse model of maximal electroshock

scientific article published on 29 June 2007

Isobolographic and behavioral characterizations of interactions between vigabatrin and gabapentin in two experimental models of epilepsy

scientific article published on 31 July 2008

Isobolographic and subthreshold analysis of interactions among felbamate and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice

scientific article published in October 2004

Isobolographic and subthreshold methods in the detection of interactions between oxcarbazepine and conventional antiepileptics--a comparative study

scientific article published in September 2003

Isobolographic characterisation of interactions among selected newer antiepileptic drugs in the mouse pentylenetetrazole-induced seizure model

scientific article published in July 2005

Isobolographic characterization of interactions between vigabatrin and tiagabine in two experimental models of epilepsy

scientific article published on 3 January 2007

Isobolographic characterization of interactions of levetiracetam with the various antiepileptic drugs in the mouse 6 Hz psychomotor seizure model.

scientific article published on 10 July 2009

Isobolographic characterization of interactions of retigabine with carbamazepine, lamotrigine, and valproate in the mouse maximal electroshock-induced seizure model.

scientific article

Isobolographic characterization of the anticonvulsant interaction profiles of levetiracetam in combination with clonazepam, ethosuximide, phenobarbital and valproate in the mouse pentylenetetrazole-induced seizure model.

scientific article published on 23 July 2009

Isobolographic profile of interactions between tiagabine and gabapentin: a preclinical study

scientific article published on 19 February 2004

Ivabradine (a hyperpolarization activated cyclic nucleotide-gated channel blocker) elevates the threshold for maximal electroshock-induced tonic seizures in mice

scientific article published in January 2013

Ivabradine attenuates the anticonvulsant potency of lamotrigine, but not that of lacosamide, pregabalin and topiramate in the tonic-clonic seizure model in mice.

scientific article published on 22 April 2017

Levetiracetam and felbamate interact both pharmacodynamically and pharmacokinetically: an isobolographic analysis in the mouse maximal electroshock model

scientific article published on 5 February 2007

Levetiracetam combined with ACEA, highly selective cannabinoid CB1 receptor agonist changes neurogenesis in mouse brain

scientific article published on 12 December 2018

Levetiracetam selectively potentiates the acute neurotoxic effects of topiramate and carbamazepine in the rotarod test in mice

scientific article published in December 2005

Long-term vigabatrin treatment modifies pentylenetetrazole-induced seizures in mice: focused on GABA brain concentration

scientific article published on 20 December 2019

Low dose of bupropion significantly enhances the anticonvulsant activity of felbamate, lamotrigine and topiramate in mice

scientific article published on 29 October 2010

Mechanisms of epileptogenesis and preclinical approach to antiepileptogenic therapies

scientific article published on 16 July 2017

Modafinil and its metabolites enhance the anticonvulsant action of classical antiepileptic drugs in the mouse maximal electroshock-induced seizure model.

scientific article published on 21 February 2015

Modified western blot technique in fast detection of heme oxygenase (HO-1/HO-2) in various tissues and organs of experimental animals.

scientific article published in January 2004

Modulation of adenosinergic system and its application for the treatment of epilepsy.

scientific article

Molecular mechanism of action and safety of 5-(3-chlorophenyl)-4-hexyl-2,4-dihydro-3H-1,2,4-triazole-3-thione - a novel anticonvulsant drug candidate

scientific article published on 18 July 2017

Molsidomine enhances the protective activity of valproate against pentylenetetrazole-induced seizures in mice

scientific article published in April 2002

Mood disorders in patients with epilepsy.

scientific article published on July 2007

Multifunctional Hybrid Compounds Derived from 2-(2,5-Dioxopyrrolidin-1-yl)-3-methoxypropanamides with Anticonvulsant and Antinociceptive Properties

scientific article published on 21 September 2017

N-(anilinomethyl)-p-isopropoxyphenylsuccinimide potentiates the anticonvulsant action of phenobarbital and valproate in the mouse maximal electroshock-induced seizure model.

scientific article published on 31 March 2009

N-Acetyl-L-cysteine Affects Ototoxicity Evoked by Amikacin and Furosemide Either Alone or in Combination in a Mouse Model of Hearing Threshold Decrease

scientific article published in 2023

N-Benzyl-(2,5-dioxopyrrolidin-1-yl)propanamide (AS-1) with Hybrid Structure as a Candidate for a Broad-Spectrum Antiepileptic Drug

scientific article published on 01 January 2020

Nefopam enhances the protective activity of antiepileptics against maximal electroshock-induced convulsions in mice

scientific article published on 01 May 2011

Neurogenesis in the epileptic brain: a brief overview from temporal lobe epilepsy

scientific article published on January 2011

Neuroprotective activity of antiepileptic drugs

scientific article

New derivative of 1,2,4-triazole-3-thione (TP427) potentiates the anticonvulsant action of valproate, but not that of carbamazepine, phenytoin or phenobarbital in the mouse tonic-clonic seizure model

scientific article published on 06 January 2019

New hybrid molecules with anticonvulsant and antinociceptive activity derived from 3-methyl- or 3,3-dimethyl-1-[1-oxo-1-(4-phenylpiperazin-1-yl)propan-2-yl]pyrrolidine-2,5-diones.

scientific article published on 18 December 2015

Non-competitive metabotropic glutamate subtype 5 receptor antagonist (SIB-1893) decreases body temperature in rats

scientific article published in November 2005

Omeprazole affects neither electroconvulsive threshold nor anticonvulsant activity of diphenylhydantoin and carbamazepine in mice.

scientific article published in July 2005

Osthole suppresses seizures in the mouse maximal electroshock seizure model.

scientific article published on 21 February 2009

Pharmacodynamic and pharmacokinetic characterization of interactions between levetiracetam and numerous antiepileptic drugs in the mouse maximal electroshock seizure model: an isobolographic analysis

scientific article published in January 2006

Pharmacodynamic and pharmacokinetic interaction profiles of levetiracetam in combination with gabapentin, tiagabine and vigabatrin in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis

scientific article published on 11 January 2009

Pharmacodynamic and pharmacokinetic interaction studies of loreclezole with felbamate, lamotrigine, topiramate, and oxcarbazepine in the mouse maximal electroshock seizure model

scientific article published in March 2005

Pharmacodynamic and pharmacokinetic interactions between common antiepileptic drugs and acetone, the chief anticonvulsant ketone body elevated in the ketogenic diet in mice.

scientific article published on 24 October 2008

Pharmacodynamic and/or pharmacokinetic characteristics of interactions between loreclezole and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice: an isobolographic analysis

scientific article

Pharmacokinetic and pharmacodynamic interactions of aminophylline and topiramate in the mouse maximal electroshock-induced seizure model

scientific article published in February 2007

Pharmacological and behavioral characteristics of interactions between vigabatrin and conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice: an isobolographic analysis

scientific article published in May 2005

Polygonogram and isobolographic analysis of interactions between various novel antiepileptic drugs in the 6-Hz corneal stimulation-induced seizure model in mice

scientific article published on 01 June 2020

Polygonogram with isobolographic synergy for three-drug combinations of phenobarbital with second-generation antiepileptic drugs in the tonic-clonic seizure model in mice

scientific article published on 06 October 2020

Preclinical evaluation of 1,2,4-triazole-based compounds targeting voltage-gated sodium channels (VGSCs) as promising anticonvulsant drug candidates

scientific article published on 17 October 2019

Preclinical profile of combinations of some second-generation antiepileptic drugs: an isobolographic analysis

scientific article

Prenyloxyphenylpropanoids as a novel class of anticonvulsive agents

scientific article published on 26 July 2009

Pretreatment with a glutamine synthetase inhibitor MSO delays the onset of initial seizures induced by pilocarpine in juvenile rats

scientific article published in February 2021

Proconvulsant effects of the ketogenic diet in electroshock-induced seizures in mice

scientific article published on 20 September 2016

Progesterone therapy in women with epilepsy

scientific article published on 01 January 2013

Protective action of nicotinic acid benzylamide in a variety of chemically-induced seizures in mice

scientific article published on 9 October 2015

Purification and anticonvulsant activity of xanthotoxin (8-methoxypsoralen)

scientific article published in January 2014

SIB 1893, a selective mGluR5 receptor antagonist, potentiates the anticonvulsant activity of oxcarbazepine against amygdala-kindled convulsions in rats.

scientific article published in July 2004

Seizure susceptibility to electroconvulsions or pentylenetetrazol after complete cerebral ischemia in rats due to cardiac arrest.

scientific article published on 18 November 2014

Sib 1893 possesses pro- and anticonvulsant activity in the electroshock seizure threshold test in mice

scientific article published on 01 September 2002

Sildenafil influences the anticonvulsant activity of vigabatrin and gabapentin in the timed pentylenetetrazole infusion test in mice.

scientific article published on 5 June 2012

Spironolactone potentiates the protective action of some selected antiepileptic drugs against maximal electroshock-induced seizures in mice

article published in 2009

Studies on the anticonvulsant activity and influence on GABA-ergic neurotransmission of 1,2,4-triazole-3-thione- based compounds

Studies on the anticonvulsant activity of 4-alkyl-1,2,4-triazole-3-thiones and their effect on GABAergic system

scientific article published on 16 September 2014

Sub-additive (antagonistic) interaction of lacosamide with lamotrigine and valproate in the maximal electroshock-induced seizure model in mice: an isobolographic analysis

scientific article published on 07 June 2020

Superior anticancer activity is demonstrated by total extract of Curcuma longa L. as opposed to individual curcuminoids separated by centrifugal partition chromatography

scientific article published on 24 January 2018

Synergistic Interaction of Retigabine with Levetiracetam in the Mouse Maximal Electroshock-Induced Seizure Model: A Type II Isobolographic Analysis.

scientific article

Synergistic interaction of gabapentin and oxcarbazepine in the mouse maximal electroshock seizure model--an isobolographic analysis

scientific article published in May 2005

Synergistic interaction of gabapentin with tiagabine in the formalin test in mice: an isobolographic analysis

scientific article

Synergistic interaction of gabapentin with tiagabine in the hot-plate test in mice: an isobolographic analysis

scientific article

Synergistic interaction of pregabalin with the synthetic cannabinoid WIN 55,212-2 mesylate in the hot-plate test in mice: an isobolographic analysis.

scientific article

Synergistic or Additive Pharmacological Interactions between Magnoflorine and Cisplatin in Human Cancer Cells of Different Histological Origin

scientific article published on 19 April 2020

Synergy, Additivity, and Antagonism between Cisplatin and Selected Coumarins in Human Melanoma Cells ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2021

Synthesis and biological investigation of new equatorial (β) stereoisomers of 3-aminotropane arylamides with atypical antipsychotic profile

scientific article published on 20 June 2016

Synthesis and biological investigation of potential atypical antipsychotics with a tropane core. Part 1

scientific article published on 26 July 2011

Synthesis, characterization and preliminary anticonvulsant evaluation of some 4-alkyl-1,2,4-triazoles.

scientific article published on 23 November 2012

Synthetic cannabinoid WIN 55,212-2 mesylate enhances the protective action of four classical antiepileptic drugs against maximal electroshock-induced seizures in mice

scientific article published on 14 January 2011

The anticonvulsant and anti-plasmid conjugation potential of Thymus vulgaris chemistry: An in vivo murine and in vitro study

scientific article published in October 2018

The interactions of atorvastatin and fluvastatin with carbamazepine, phenytoin and valproate in the mouse maximal electroshock seizure model

scientific article published on 26 October 2011

Third-generation antiepileptic drugs: mechanisms of action, pharmacokinetics and interactions

scientific article (publication date: 2009)

Three-dimensional isobolographic analysis of interactions between lamotrigine and clonazepam in maximal electroshock-induced seizures in mice

scientific article published on 23 October 2004

Tiagabine synergistically interacts with gabapentin in the electroconvulsive threshold test in mice

scientific article

Time-course and dose-response relationships of imperatorin in the mouse maximal electroshock seizure threshold model

scientific article published on 25 May 2007

Vitamin C alleviates ototoxic effect caused by coadministration of amikacin and furosemide

scientific article published on 04 January 2019

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