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List of works by Nicholas J Harmer

1.15 A crystal structure of the X. tropicalis Spred1 EVH1 domain suggests a fourth distinct peptide-binding mechanism within the EVH1 family.

scientific article published in February 2005

A Murder Mystery Gamification Session to Consolidate Analytical Biochemical Techniques Learning

scientific article published in 2023

A Structural Biology Approach Enables the Development of Antimicrobials Targeting Bacterial Immunophilins

scientific article

A half-site multimeric enzyme achieves its cooperativity without conformational changes

scientific article published on 28 November 2017

A universal fluorescence-based toolkit for real-time quantification of DNA and RNA nuclease activity

A universal fluorescence-based toolkit for real-time quantification of DNA and RNA nuclease activity

scientific article published on 20 June 2019

Achieving high signal-to-noise in cell regulatory systems: Spatial organization of multiprotein transmembrane assemblies of FGFR and MET receptors.

scientific article published on 5 May 2015

Broad-spectrum in vitro activity of macrophage infectivity potentiator inhibitors against Gram-negative bacteria and Leishmania major

scientific article published on 01 May 2022

Characterization of Carboxylic Acid Reductases as Enzymes in the Toolbox for Synthetic Chemistry.

scientific article published on 14 February 2017

Cloning, expression, purification and preliminary crystallographic analysis of the short-chain dehydrogenase enzymes WbmF, WbmG and WbmH from Bordetella bronchiseptica

scientific article published on 28 July 2007

Determination of protein-ligand interactions using differential scanning fluorimetry

scientific article

Engineering a Seven Enzyme Biotransformation using Mathematical Modelling and Characterized Enzyme Parts

scientific article published on 04 July 2019

Expression and purification of recombinant human fibroblast growth factor receptor in Escherichia coli.

scientific article published on 27 April 2006

Highly thermostable carboxylic acid reductases generated by ancestral sequence reconstruction

scientific article published on 22 November 2019

Identification of type II toxin-antitoxin modules in Burkholderia pseudomallei.

scientific article published on 16 November 2012

Molecular features of lipoprotein CD0873: A potential vaccine against the human pathogen Clostridioides difficile

scientific article published on 16 August 2019

Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin.

scientific article published in February 2006

Predicting Protein Function from Structure—The Roles of Short-chain Dehydrogenase/Reductase Enzymes in Bordetella O-antigen Biosynthesis

scientific article

Pseudomonas aeruginosa Expresses a Functional Human Natriuretic Peptide Receptor Ortholog: Involvement in Biofilm Formation

scientific article published on 25 August 2015

Structural insights into WcbI, a novel polysaccharide-biosynthesis enzyme

scientific article

The HicA toxin from Burkholderia pseudomallei has a role in persister cell formation

scientific article

The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity

scientific article

The structural biology of growth factor receptor activation

scientific article published in January 2003

The structure of a Burkholderia pseudomallei immunophilin–inhibitor complex reveals new approaches to antimicrobial development

scientific article

Unraveling the B. pseudomallei Heptokinase WcbL: From Structure to Drug Discovery

scientific article published in December 2015

Using enzyme cascades in biocatalysis: Highlight on transaminases and carboxylic acid reductases

scientific article published on 16 November 2019

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