List of works - Paolo Melchiorre

A Photochemical Organocatalytic Strategy for the α-Alkylation of Ketones by using Radicals

scientific article published on 13 February 2020

A Redox-Active Nickel Complex that Acts as an Electron Mediator in Photochemical Giese Reactions

scientific article published on 06 March 2019

A mechanistic rationale for the 9-amino(9-deoxy)epi cinchona alkaloids catalyzed asymmetric reactions via iminium ion activation of enones

scientific article published on 07 June 2013

A visible-light mediated three-component radical process using dithiocarbamate anion catalysis

scientific article published on 30 April 2019

Alcohols and di-tert-butyl dicarbonate: how the nature of the Lewis acid catalyst may address the reaction to the synthesis of tert-butyl ethers

Amide Synthesis by Nickel/Photoredox-Catalyzed Direct Carbamoylation of (Hetero)Aryl Bromides

scientific article published on 25 February 2020

Aminocatalytic enantioselective 1,6 additions of alkyl thiols to cyclic dienones: vinylogous iminium ion activation

scientific article published on 22 May 2012

Aminocatalytic enantioselective anti-Mannich reaction of aldehydes with in situ generated N-Cbz and N-Boc imines

scientific article published on 01 January 2008

Asymmetric Photocatalytic C-H Functionalization of Toluene and Derivatives

scientific article published on 22 June 2018

Asymmetric aminocatalysis--gold rush in organic chemistry

scientific article published on January 2008

Asymmetric aminolysis of aromatic epoxides: a facile catalytic enantioselective synthesis of anti-beta-amino alcohols

scientific article published in 2004

Asymmetric catalysis of Diels-Alder reactions with in situ generated heterocyclic ortho-quinodimethanes

scientific article published on 02 September 2011

Asymmetric catalytic aziridination of cyclic enones

scientific article published in July 2010

Asymmetric catalytic formation of quaternary carbons by iminium ion trapping of radicals

scientific article published in April 2016

Asymmetric catalytic synthesis of enantiopure N-protected 1,2-amino alcohols

scientific article published in 2004

Asymmetric iminium ion catalysis with a novel bifunctional primary amine thiourea: controlling adjacent quaternary and tertiary stereocenters

scientific article published in August 2009

Asymmetric organocatalytic cascade reactions with alpha-substituted alpha,beta-unsaturated aldehydes

article

Asymmetric vinylogous Diels-Alder reactions catalyzed by a chiral phosphoric acid

scientific article published on 06 February 2014

Asymmetric vinylogous aldol reaction via H-bond-directing dienamine catalysis

scientific article published on 21 December 2012

Bifunctional catalysis by natural cinchona alkaloids: a mechanism explained.

scientific article published in August 2009

Brønsted acid-catalysed conjugate addition of photochemically generated α-amino radicals to alkenylpyridines

scientific article published on 03 February 2016

Chemistry glows green with photoredox catalysis

scientific article published on 06 February 2020

Cinchona-based primary amine catalysis in the asymmetric functionalization of carbonyl compounds.

scientific article published on 15 August 2012

Computational study with DFT and kinetic models on the mechanism of photoinitiated aromatic perfluoroalkylations

scientific article published on 14 May 2015

Control of remote stereochemistry in the synthesis of spirocyclic oxindoles: vinylogous organocascade catalysis

scientific article published on 16 April 2013

Controlling stereoselectivity in the aminocatalytic enantioselective Mannich reaction of aldehydes with in situ generated N-carbamoyl imines

scientific article published on 01 May 2010

Controlling the molecular topology of vinylogous iminium ions by logical substrate design: highly regio- and stereoselective aminocatalytic 1,6-addition to linear 2,4-dienals

scientific article published on 03 September 2013

Cooperative organocatalysis for the asymmetric γ alkylation of α-branched enals

scientific article published on 01 December 2010

Cr(Salen)-catalyzed addition of 1,3-dichloropropene to aromatic aldehydes. A simple access to optically active vinyl epoxides.

scientific article published in April 2001

Diastereodivergent asymmetric sulfa-Michael additions of α-branched enones using a single chiral organic catalyst

scientific article published on 13 October 2011

Diastereodivergent organocatalysis for the asymmetric synthesis of chiral annulated furans.

scientific article published on 27 April 2015

Dioxindole in asymmetric catalytic synthesis: direct access to 3-substituted 3-hydroxy-2-oxindoles via 1,4-additions to nitroalkenes.

scientific article

Dioxindole in asymmetric catalytic synthesis: routes to enantioenriched 3-substituted 3-hydroxyoxindoles and the preparation of maremycin A

scientific article published on 15 December 2011

Direct asymmetric vinylogous Michael addition of cyclic enones to nitroalkenes via dienamine catalysis

scientific article

Direct catalytic enantioselective vinylogous aldol reaction of α-branched enals with isatins

scientific article published on 18 October 2012

Direct catalytic synthesis of enantiopure 5-substituted oxazolidinones from racemic terminal epoxides

scientific article published in 2005

Direct enantioselective Michael addition of aldehydes to vinyl ketones catalyzed by chiral amines

scientific article published in May 2003

Enantioselective Formal α-Methylation and α-Benzylation of Aldehydes by Means of Photo-organocatalysis.

scientific article published on 21 March 2017

Enantioselective Organocatalytic Diels-Alder Trapping of Photochemically Generated Hydroxy-o-Quinodimethanes.

scientific article published on 21 January 2016

Enantioselective Photochemical Organocascade Catalysis

scientific article

Enantioselective Vinylogous Organocascade Reactions.

scientific article published on 3 June 2016

Enantioselective organocatalytic alkylation of aldehydes and enals driven by the direct photoexcitation of enamines.

scientific article published on 11 March 2015

Enantioselective radical conjugate additions driven by a photoactive intramolecular iminium-ion-based EDA complex

scientific article published in Nature Communications

Extending the aminocatalytic HOMO-raising activation strategy: where is the limit?

scientific article published on 04 April 2012

Forging Fluorine-Containing Quaternary Stereocenters by a Light-Driven Organocatalytic Aldol Desymmetrization Process

scientific article published on 26 July 2017

InBr3-catalyzed Friedel-Crafts addition of indoles to chiral aromatic epoxides: a facile route to enantiopure indolyl derivatives.

scientific article

Kinetic resolution of epoxides by a C-C bond-forming reaction: highly enantioselective addition of indoles to cis, trans, and meso aromatic epoxides catalyzed by [Cr(salen)] complexes

article

Light in aminocatalysis: the asymmetric intermolecular alpha-alkylation of aldehydes

scientific article published on 01 January 2009

Light-Driven Enantioselective Organocatalytic β-Benzylation of Enals.

scientific article published on 10 February 2017

Mechanism of the Stereoselective α-Alkylation of Aldehydes Driven by the Photochemical Activity of Enamines.

scientific article

Mechanistic Studies in Photocatalysis

scientific article published on 15 January 2019

Metal-free photochemical aromatic perfluoroalkylation of α-cyano arylacetates

scientific article published on 25 March 2014

Multicatalytic asymmetric synthesis of complex tetrahydrocarbazoles via a Diels-Alder/benzoin reaction sequence

scientific article published on 16 February 2012

Multiple approaches to enantiopure spirocyclic benzofuranones using organocatalytic cascade reactions

scientific article published on 19 August 2010

Organocascade reactions of enones catalyzed by a chiral primary amine

scientific article published on 01 January 2009

Organocatalytic asymmetric Friedel-Crafts alkylation of indoles with simple alpha,beta-unsaturated ketones

article by Giuseppe Bartoli et al published 29 March 2007 in Organic Letters

Organocatalytic asymmetric alpha-halogenation of 1,3-dicarbonyl compounds

Organocatalytic asymmetric alpha-selenenylation of aldehydes

scientific article published on 01 January 2007

Organocatalytic asymmetric aziridination of enones

scientific article published on 01 January 2008

Organocatalytic asymmetric conjugate addition of 1,3-dicarbonyl compounds to maleimides

article

Organocatalytic asymmetric hydrophosphination of alpha,beta-unsaturated aldehydes

article by Armando Carlone et al published 2007 in Angewandte Chemie International Edition

Organocatalytic asymmetric hydrophosphination of nitroalkenes

article published in 2007

Perchloric acid and its salts: very powerful catalysts in organic chemistry

scientific article published on 01 June 2010

Photo-Organocatalytic Enantioselective Radical Cascade Reactions of Unactivated Olefins

scientific article published on 31 August 2018

Photo-organocatalysis of atom-transfer radical additions to alkenes

scientific article published on 22 September 2014

Photo-organocatalytic Enantioselective Perfluoroalkylation of β-Ketoesters.

scientific article published on 24 April 2015

Photochemical Asymmetric Nickel-Catalyzed Acyl Cross-Coupling

scientific article published on 07 October 2019

Photochemical C-H Hydroxyalkylation of Quinolines and Isoquinolines

scientific article published on 11 October 2019

Photochemical Chemoselective Alkylation of Tryptophan-Containing Peptides

scientific article published on 05 January 2021

Photochemical activity of a key donor-acceptor complex can drive stereoselective catalytic α-alkylation of aldehydes

scientific article published on 11 August 2013

Photochemical generation of acyl and carbamoyl radicals using a nucleophilic organic catalyst: applications and mechanism thereof

scientific article published on 04 June 2020

Photochemical generation of radicals from alkyl electrophiles using a nucleophilic organic catalyst

scientific article published on 03 December 2018

Photoredox Organocatalysis for the Enantioselective Synthesis of 1,7-Dicarbonyl Compounds

scientific article published in 2022

Proline-catalyzed asymmetric formal alpha-alkylation of aldehydes via vinylogous iminium ion intermediates generated from arylsulfonyl indoles

scientific article

Quaternary stereogenic carbon atoms in complex molecules by an asymmetric, organocatalytic, triple-cascade reaction

scientific article published on 01 January 2008

Radical-Based C-C Bond-Forming Processes Enabled by the Photoexcitation of 4-Alkyl-1,4-dihydropyridines.

scientific article published on 6 October 2017

Sequential one-pot InBr(3)-catalyzed 1,4- then 1,2-nucleophilic addition to enones

scientific article published in May 2002

Stereocontrolled Synthesis of 1,4-Dicarbonyl Compounds by Photochemical Organocatalytic Acyl Radical Addition to Enals

scientific article published on 20 December 2018

Studies on the Enantioselective Iminium Ion Trapping of Radicals Triggered by an Electron-Relay Mechanism

scientific article published on 10 March 2017

Synthesis and binding activity of endomorphin-1 analogues containing beta-amino acids.

scientific article published in December 2000

Synthesis of 9-amino(9-deoxy)epi cinchona alkaloids, general chiral organocatalysts for the stereoselective functionalization of carbonyl compounds

scientific article published on 17 January 2013

Synthetic Methods Driven by the Photoactivity of Electron Donor-Acceptor Complexes

scientific article published on 12 March 2020

Targeting structural and stereochemical complexity by organocascade catalysis: construction of spirocyclic oxindoles having multiple stereocenters

scientific article published in January 2009

The First Catalytic Enantioselective Nozaki-Hiyama Reaction

scientific article published on 01 November 1999

Unusual and unexpected reactivity of t-butyl dicarbonate (Boc2O) with alcohols in the presence of magnesium perchlorate. A new and general route to t-butyl ethers

scholarly article by Giuseppe Bartoli et al published 3 February 2005 in Organic Letters

Visible-light excitation of iminium ions enables the enantioselective catalytic β-alkylation of enals.

scientific article

When asymmetric aminocatalysis meets the vinylogy principle

scientific article published in May 2013

List of works by Paolo Melchiorre

A Photochemical Organocatalytic Strategy for the α-Alkylation of Ketones by using Radicals

A Redox-Active Nickel Complex that Acts as an Electron Mediator in Photochemical Giese Reactions

A mechanistic rationale for the 9-amino(9-deoxy)epi cinchona alkaloids catalyzed asymmetric reactions via iminium ion activation of enones

A visible-light mediated three-component radical process using dithiocarbamate anion catalysis

Alcohols and di-tert-butyl dicarbonate: how the nature of the Lewis acid catalyst may address the reaction to the synthesis of tert-butyl ethers

Amide Synthesis by Nickel/Photoredox-Catalyzed Direct Carbamoylation of (Hetero)Aryl Bromides

Aminocatalytic enantioselective 1,6 additions of alkyl thiols to cyclic dienones: vinylogous iminium ion activation

Aminocatalytic enantioselective anti-Mannich reaction of aldehydes with in situ generated N-Cbz and N-Boc imines

Asymmetric Photocatalytic C-H Functionalization of Toluene and Derivatives

Asymmetric aminocatalysis--gold rush in organic chemistry

Asymmetric aminolysis of aromatic epoxides: a facile catalytic enantioselective synthesis of anti-beta-amino alcohols

Asymmetric catalysis of Diels-Alder reactions with in situ generated heterocyclic ortho-quinodimethanes

Asymmetric catalytic aziridination of cyclic enones

Asymmetric catalytic formation of quaternary carbons by iminium ion trapping of radicals

Asymmetric catalytic synthesis of enantiopure N-protected 1,2-amino alcohols

Asymmetric iminium ion catalysis with a novel bifunctional primary amine thiourea: controlling adjacent quaternary and tertiary stereocenters

Asymmetric organocatalytic cascade reactions with alpha-substituted alpha,beta-unsaturated aldehydes

Asymmetric vinylogous Diels-Alder reactions catalyzed by a chiral phosphoric acid

Asymmetric vinylogous aldol reaction via H-bond-directing dienamine catalysis

Bifunctional catalysis by natural cinchona alkaloids: a mechanism explained.

Brønsted acid-catalysed conjugate addition of photochemically generated α-amino radicals to alkenylpyridines

Chemistry glows green with photoredox catalysis

Cinchona-based primary amine catalysis in the asymmetric functionalization of carbonyl compounds.

Computational study with DFT and kinetic models on the mechanism of photoinitiated aromatic perfluoroalkylations

Control of remote stereochemistry in the synthesis of spirocyclic oxindoles: vinylogous organocascade catalysis

Controlling stereoselectivity in the aminocatalytic enantioselective Mannich reaction of aldehydes with in situ generated N-carbamoyl imines

Controlling the molecular topology of vinylogous iminium ions by logical substrate design: highly regio- and stereoselective aminocatalytic 1,6-addition to linear 2,4-dienals

Cooperative organocatalysis for the asymmetric γ alkylation of α-branched enals

Cr(Salen)-catalyzed addition of 1,3-dichloropropene to aromatic aldehydes. A simple access to optically active vinyl epoxides.

Diastereodivergent asymmetric sulfa-Michael additions of α-branched enones using a single chiral organic catalyst

Diastereodivergent organocatalysis for the asymmetric synthesis of chiral annulated furans.

Dioxindole in asymmetric catalytic synthesis: direct access to 3-substituted 3-hydroxy-2-oxindoles via 1,4-additions to nitroalkenes.

Dioxindole in asymmetric catalytic synthesis: routes to enantioenriched 3-substituted 3-hydroxyoxindoles and the preparation of maremycin A

Direct asymmetric vinylogous Michael addition of cyclic enones to nitroalkenes via dienamine catalysis

Direct catalytic enantioselective vinylogous aldol reaction of α-branched enals with isatins

Direct catalytic synthesis of enantiopure 5-substituted oxazolidinones from racemic terminal epoxides

Direct enantioselective Michael addition of aldehydes to vinyl ketones catalyzed by chiral amines

Enantioselective Formal α-Methylation and α-Benzylation of Aldehydes by Means of Photo-organocatalysis.

Enantioselective Organocatalytic Diels-Alder Trapping of Photochemically Generated Hydroxy-o-Quinodimethanes.

Enantioselective Photochemical Organocascade Catalysis

Enantioselective Vinylogous Organocascade Reactions.

Enantioselective organocatalytic alkylation of aldehydes and enals driven by the direct photoexcitation of enamines.

Enantioselective radical conjugate additions driven by a photoactive intramolecular iminium-ion-based EDA complex

Extending the aminocatalytic HOMO-raising activation strategy: where is the limit?

Forging Fluorine-Containing Quaternary Stereocenters by a Light-Driven Organocatalytic Aldol Desymmetrization Process

InBr3-catalyzed Friedel-Crafts addition of indoles to chiral aromatic epoxides: a facile route to enantiopure indolyl derivatives.

Kinetic resolution of epoxides by a C-C bond-forming reaction: highly enantioselective addition of indoles to cis, trans, and meso aromatic epoxides catalyzed by [Cr(salen)] complexes

Light in aminocatalysis: the asymmetric intermolecular alpha-alkylation of aldehydes

Light-Driven Enantioselective Organocatalytic β-Benzylation of Enals.

Mechanism of the Stereoselective α-Alkylation of Aldehydes Driven by the Photochemical Activity of Enamines.

Mechanistic Studies in Photocatalysis

Metal-free photochemical aromatic perfluoroalkylation of α-cyano arylacetates

Multicatalytic asymmetric synthesis of complex tetrahydrocarbazoles via a Diels-Alder/benzoin reaction sequence

Multiple approaches to enantiopure spirocyclic benzofuranones using organocatalytic cascade reactions

Organocascade reactions of enones catalyzed by a chiral primary amine

Organocatalytic asymmetric Friedel-Crafts alkylation of indoles with simple alpha,beta-unsaturated ketones

Organocatalytic asymmetric alpha-halogenation of 1,3-dicarbonyl compounds

Organocatalytic asymmetric alpha-selenenylation of aldehydes

Organocatalytic asymmetric aziridination of enones

Organocatalytic asymmetric conjugate addition of 1,3-dicarbonyl compounds to maleimides

Organocatalytic asymmetric hydrophosphination of alpha,beta-unsaturated aldehydes

Organocatalytic asymmetric hydrophosphination of nitroalkenes

Perchloric acid and its salts: very powerful catalysts in organic chemistry

Photo-Organocatalytic Enantioselective Radical Cascade Reactions of Unactivated Olefins

Photo-organocatalysis of atom-transfer radical additions to alkenes

Photo-organocatalytic Enantioselective Perfluoroalkylation of β-Ketoesters.

Photochemical Asymmetric Nickel-Catalyzed Acyl Cross-Coupling

Photochemical C-H Hydroxyalkylation of Quinolines and Isoquinolines

Photochemical Chemoselective Alkylation of Tryptophan-Containing Peptides

Photochemical activity of a key donor-acceptor complex can drive stereoselective catalytic α-alkylation of aldehydes

Photochemical generation of acyl and carbamoyl radicals using a nucleophilic organic catalyst: applications and mechanism thereof

Photochemical generation of radicals from alkyl electrophiles using a nucleophilic organic catalyst

Photoredox Organocatalysis for the Enantioselective Synthesis of 1,7-Dicarbonyl Compounds

Proline-catalyzed asymmetric formal alpha-alkylation of aldehydes via vinylogous iminium ion intermediates generated from arylsulfonyl indoles

Quaternary stereogenic carbon atoms in complex molecules by an asymmetric, organocatalytic, triple-cascade reaction

Radical-Based C-C Bond-Forming Processes Enabled by the Photoexcitation of 4-Alkyl-1,4-dihydropyridines.

Sequential one-pot InBr(3)-catalyzed 1,4- then 1,2-nucleophilic addition to enones

Stereocontrolled Synthesis of 1,4-Dicarbonyl Compounds by Photochemical Organocatalytic Acyl Radical Addition to Enals

Studies on the Enantioselective Iminium Ion Trapping of Radicals Triggered by an Electron-Relay Mechanism