List of works - Dmitry B Veprintsev

14-3-3 activation of DNA binding of p53 by enhancing its association into tetramers

scientific article

A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling

scientific article published on 18 April 2017

A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants

scientific article

A targeted approach for the synthesis of multi-phosphorylated peptides: a tool for studying the role of phosphorylation patterns in proteins

scientific article published on 01 October 2019

AAscan, PCRdesign and MutantChecker: a suite of programs for primer design and sequence analysis for high-throughput scanning mutagenesis.

scientific article

Acetylation of lysine 120 of p53 endows DNA-binding specificity at effective physiological salt concentration

scientific article

Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA.

scientific article published on 30 January 2008

An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid

scientific article

Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor

scientific article published on 3 February 2016

Bin2 is a membrane sculpting N-BAR protein that influences leucocyte podosomes, motility and phagocytosis

scientific article

Binding of EMSY to HP1beta: implications for recruitment of HP1beta and BS69

scientific article

Binding of Rad51 and other peptide sequences to a promiscuous, highly electrostatic binding site in p53.

scientific article published on 20 December 2004

Binding of natively unfolded HIF-1alpha ODD domain to p53

scientific journal article

CRINEPT-TROSY NMR reveals p53 core domain bound in an unfolded form to the chaperone Hsp90.

scientific article

Cdc48-like protein of actinobacteria (Cpa) is a novel proteasome interactor in mycobacteria and related organisms.

scientific article

Comparative binding of p53 to its promoter and DNA recognition elements.

scientific article published in May 2005

Comparison of BRCT domains of BRCA1 and 53BP1: a biophysical analysis

scientific article

Conservation of DNA-binding specificity and oligomerisation properties within the p53 family

scientific article

Cooperative binding of tetrameric p53 to DNA.

scientific article published in August 2004

Cooperative thermal transitions of bovine and human apo-α-lactalbumins: evidence for a new intermediate state

article

Core domain interactions in full-length p53 in solution

scholarly article

Correction: Bin2 Is a Membrane Sculpting N-BAR Protein That Influences Leucocyte Podosomes, Motility and Phagocytosis.

scientific article published on 8 August 2013

Corrigendum to “The DNA-Binding Domain of Human PARP-1 Interacts with DNA Single-Strand Breaks as a Monomer through Its Second Zinc Finger” [J. Mol. Biol. 407 (2011) 149–170].

scientific article published in June 2012

Crystal structure of HEL4, a soluble, refoldable human V(H) single domain with a germ-line scaffold

scientific article published in April 2004

Crystal structure of the ENT domain of human EMSY.

scientific article

Crystallization scale preparation of a stable GPCR signaling complex between constitutively active rhodopsin and G-protein

scientific article

Dissecting the Relation between a nuclear receptor and GATA: binding affinity studies of thyroid hormone receptor and GATA2 on TSHβ promoter

scientific article

Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation

scientific article published on 19 March 2019

Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region

scientific article published on 15 August 2016

ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes

scientific article

Effects of CpG methylation on recognition of DNA by the tumour suppressor p53.

scientific article published on 6 December 2008

Effects of oncogenic mutations and DNA response elements on the binding of p53 to p53-binding protein 2 (53BP2).

scientific article published on 2 August 2006

Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA

scientific article

End binding proteins are obligatory dimers

scientific article

Features critical for membrane binding revealed by DivIVA crystal structure

scientific article

Fine tuning the N-terminus of a calcium binding protein: alpha-lactalbumin

scientific article published on 01 October 1999

Fine tuning the N‐terminus of a calcium binding protein: α‐lactalbumin

scholarly article by Dmitry B. Veprintsev published in October 1999

High-throughput Site-directed Scanning Mutagenesis Using a Two-fragment PCR Approach

publication published on 05 January 2020

High-throughput mutagenesis using a two-fragment PCR approach

scientific article published on 28 July 2017

Hsp90-Tau complex reveals molecular basis for specificity in chaperone action

scientific article

Human full-length Securin is a natively unfolded protein

scientific article published in June 2005

Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium

scholarly article

Insights into congenital stationary night blindness based on the structure of G90D rhodopsin

scientific article

Insights into the Basal Activity and Activation Mechanism of the β1 Adrenergic Receptor Using Native Mass Spectrometry

scientific article published on 03 December 2018

Interactions of alpha-lactalbumins with lipid vesicles studied by tryptophan fluorescence.

scientific article published in March 1996

Kinetic Instability of p53 Core Domain Mutants

scientific article published in Journal of Biological Chemistry

Large-scale production and protein engineering of G protein-coupled receptors for structural studies

scientific article

Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells

scientific article published on 27 November 2020

Ligand-independent assembly of recombinant human CD1 by using oxidative refolding chromatography

scholarly article

Lithocholic acid is an endogenous inhibitor of MDM4 and MDM2.

scientific article

Mechano-sensitivity of β2-adrenoceptors enhances constitutive activation of cAMP generation that is inhibited by inverse agonists

scientific article published in 2024

Modulation of binding of DNA to the C-terminal domain of p53 by acetylation

scientific article

Modulation of the oligomerization state of p53 by differential binding of proteins of the S100 family to p53 monomers and tetramers

scientific article published on 18 March 2009

Molecular basis for modulation of the p53 target selectivity by KLF4.

scientific article

Molecular basis of S100 proteins interacting with the p53 homologs p63 and p73.

scientific article

Mutating aspartate in the calcium-binding site of alpha-lactalbumin: effects on the protein stability and cation binding

scientific article published in October 2001

Native Mass Spectrometry Gives Insight into the Allosteric Binding Mechanism of M2 Pyruvate Kinase to Fructose-1,6-Bisphosphate.

scientific article published on 8 March 2018

PRIMA-1 reactivates mutant p53 by covalent binding to the core domain

scientific article published on May 2009

Pb2+ and Hg2+ binding to alpha-lactalbumin

scientific article published on 01 August 1996

Probing Gαi1 protein activation at single-amino acid resolution.

scientific article published on 10 August 2015

Production and purification of human Hsp90β in Escherichia coli

scientific article

Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor

scientific article

Recognition of DNA by p53 Core Domain and Location of Intermolecular Contacts of Cooperative Binding

scientific article published on 01 May 2002

Regulation of DNA binding of p53 by its C-terminal domain.

scientific article published in September 2004

Sequence determinants of a microtubule tip localization signal (MtLS).

scientific article

Specific recognition of p53 tetramers by peptides derived from p53 interacting proteins

scientific article

Stability of p53 homologs

scientific article

Stabilization of G protein-coupled receptors by point mutations

scientific article

Structural and mutational analysis of the cell division protein FtsQ

scientific article

Structural basis for Arl1-dependent targeting of homodimeric GRIP domains to the Golgi apparatus

scientific article

Structural evolution of p53, p63, and p73: Implication for heterotetramer formation

scientific article

Structural insight into the ESCRT-I/-II link and its role in MVB trafficking

scientific article

Structural insights into endosomal sorting complex required for transport (ESCRT-I) recognition of ubiquitinated proteins.

scientific article

Structural studies of phosphoinositide 3-kinase-dependent traffic to multivesicular bodies.

scientific article published on January 2007

Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24.

scientific article published on September 2008

Structure of AMP-PNP-bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD-F

scientific article

Structure of a human inositol 1,4,5-trisphosphate 3-kinase: substrate binding reveals why it is not a phosphoinositide 3-kinase

scientific article

Structures of SAS-6 suggest its organization in centrioles

scientific article

Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations

scientific article published on 9 February 2005

Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers

scientific article

Targeted rescue of a destabilized mutant of p53 by an in silico screened drug

scientific article

The DNA-Binding Domain of Human PARP-1 Interacts with DNA Single-Strand Breaks as a Monomer through Its Second Zinc Finger

scientific article

The central region of HDM2 provides a second binding site for p53.

scholarly article

The novel p53 isoform "delta p53" is a misfolded protein and does not bind the p21 promoter site

scientific article

The structure and interactions of the proline-rich domain of ASPP2

scientific article

The structure of the AXH domain of spinocerebellar ataxin-1

scientific article

Universal allosteric mechanism for Gα activation by GPCRs

scientific article published on 6 July 2015

Zinc binding in bovine alpha-lactalbumin: sequence homology may not be a predictor of subtle functional features

scientific article published on 01 July 2000

Zinc binding in bovine α‐lactalbumin: Sequence homology may not be a predictor of subtle functional features

scholarly article by Serge E. Permyakov published in July 2000

pH-induced transition and Zn2+ -binding properties of bovine prolactin 1

scientific article published on 01 April 1997

List of works by Dmitry B Veprintsev

14-3-3 activation of DNA binding of p53 by enhancing its association into tetramers

A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling

A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants

A targeted approach for the synthesis of multi-phosphorylated peptides: a tool for studying the role of phosphorylation patterns in proteins

AAscan, PCRdesign and MutantChecker: a suite of programs for primer design and sequence analysis for high-throughput scanning mutagenesis.

Acetylation of lysine 120 of p53 endows DNA-binding specificity at effective physiological salt concentration

Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA.

An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid

Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor

Bin2 is a membrane sculpting N-BAR protein that influences leucocyte podosomes, motility and phagocytosis

Binding of EMSY to HP1beta: implications for recruitment of HP1beta and BS69

Binding of Rad51 and other peptide sequences to a promiscuous, highly electrostatic binding site in p53.

Binding of natively unfolded HIF-1alpha ODD domain to p53

CRINEPT-TROSY NMR reveals p53 core domain bound in an unfolded form to the chaperone Hsp90.

Cdc48-like protein of actinobacteria (Cpa) is a novel proteasome interactor in mycobacteria and related organisms.

Comparative binding of p53 to its promoter and DNA recognition elements.

Comparison of BRCT domains of BRCA1 and 53BP1: a biophysical analysis

Conservation of DNA-binding specificity and oligomerisation properties within the p53 family

Cooperative binding of tetrameric p53 to DNA.

Cooperative thermal transitions of bovine and human apo-α-lactalbumins: evidence for a new intermediate state

Core domain interactions in full-length p53 in solution

Correction: Bin2 Is a Membrane Sculpting N-BAR Protein That Influences Leucocyte Podosomes, Motility and Phagocytosis.

Corrigendum to “The DNA-Binding Domain of Human PARP-1 Interacts with DNA Single-Strand Breaks as a Monomer through Its Second Zinc Finger” [J. Mol. Biol. 407 (2011) 149–170].

Crystal structure of HEL4, a soluble, refoldable human V(H) single domain with a germ-line scaffold

Crystal structure of the ENT domain of human EMSY.

Crystallization scale preparation of a stable GPCR signaling complex between constitutively active rhodopsin and G-protein

Dissecting the Relation between a nuclear receptor and GATA: binding affinity studies of thyroid hormone receptor and GATA2 on TSHβ promoter

Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation

Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region

ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes

Effects of CpG methylation on recognition of DNA by the tumour suppressor p53.

Effects of oncogenic mutations and DNA response elements on the binding of p53 to p53-binding protein 2 (53BP2).

Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA

End binding proteins are obligatory dimers

Features critical for membrane binding revealed by DivIVA crystal structure

Fine tuning the N-terminus of a calcium binding protein: alpha-lactalbumin

Fine tuning the N‐terminus of a calcium binding protein: α‐lactalbumin

High-throughput Site-directed Scanning Mutagenesis Using a Two-fragment PCR Approach

High-throughput mutagenesis using a two-fragment PCR approach

Hsp90-Tau complex reveals molecular basis for specificity in chaperone action

Human full-length Securin is a natively unfolded protein

Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium

Insights into congenital stationary night blindness based on the structure of G90D rhodopsin

Insights into the Basal Activity and Activation Mechanism of the β1 Adrenergic Receptor Using Native Mass Spectrometry

Interactions of alpha-lactalbumins with lipid vesicles studied by tryptophan fluorescence.

Kinetic Instability of p53 Core Domain Mutants

Large-scale production and protein engineering of G protein-coupled receptors for structural studies

Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells

Ligand-independent assembly of recombinant human CD1 by using oxidative refolding chromatography

Lithocholic acid is an endogenous inhibitor of MDM4 and MDM2.

Mechano-sensitivity of β2-adrenoceptors enhances constitutive activation of cAMP generation that is inhibited by inverse agonists

Modulation of binding of DNA to the C-terminal domain of p53 by acetylation

Modulation of the oligomerization state of p53 by differential binding of proteins of the S100 family to p53 monomers and tetramers

Molecular basis for modulation of the p53 target selectivity by KLF4.

Molecular basis of S100 proteins interacting with the p53 homologs p63 and p73.

Mutating aspartate in the calcium-binding site of alpha-lactalbumin: effects on the protein stability and cation binding

Native Mass Spectrometry Gives Insight into the Allosteric Binding Mechanism of M2 Pyruvate Kinase to Fructose-1,6-Bisphosphate.

PRIMA-1 reactivates mutant p53 by covalent binding to the core domain

Pb2+ and Hg2+ binding to alpha-lactalbumin

Probing Gαi1 protein activation at single-amino acid resolution.

Production and purification of human Hsp90β in Escherichia coli

Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor

Recognition of DNA by p53 Core Domain and Location of Intermolecular Contacts of Cooperative Binding

Regulation of DNA binding of p53 by its C-terminal domain.

Sequence determinants of a microtubule tip localization signal (MtLS).

Specific recognition of p53 tetramers by peptides derived from p53 interacting proteins

Stability of p53 homologs

Stabilization of G protein-coupled receptors by point mutations

Structural and mutational analysis of the cell division protein FtsQ

Structural basis for Arl1-dependent targeting of homodimeric GRIP domains to the Golgi apparatus

Structural evolution of p53, p63, and p73: Implication for heterotetramer formation

Structural insight into the ESCRT-I/-II link and its role in MVB trafficking

Structural insights into endosomal sorting complex required for transport (ESCRT-I) recognition of ubiquitinated proteins.

Structural studies of phosphoinositide 3-kinase-dependent traffic to multivesicular bodies.

Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24.

Structure of AMP-PNP-bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD-F

Structure of a human inositol 1,4,5-trisphosphate 3-kinase: substrate binding reveals why it is not a phosphoinositide 3-kinase

Structures of SAS-6 suggest its organization in centrioles

Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations