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List of works by Stephen P. Bell

A conserved MCM single-stranded DNA binding element is essential for replication initiation

scientific article

A conserved Mcm4 motif is required for Mcm2-7 double-hexamer formation and origin DNA unwinding

scientific article published on 06 August 2019

A genomic view of eukaryotic DNA replication.

scientific article

ATP hydrolysis by ORC catalyzes reiterative Mcm2-7 assembly at a defined origin of replication

scientific article

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

scientific article (publication date: 14 May 1992)

ATPase switches controlling DNA replication initiation.

scientific article

Architecture of the Yeast Origin Recognition Complex Bound to Origins of DNA Replication ⬇️

scientific article published on December 1, 1997

Assembly of alternative multiprotein complexes directs rRNA promoter selectivity

scientific article published in June 1990

CDK prevents Mcm2-7 helicase loading by inhibiting Cdt1 interaction with Orc6

scientific article published on 2 February 2011

Cell cycle execution point analysis of ORC function and characterization of the checkpoint response to ORC inactivation in Saccharomyces cerevisiae

scientific article

Chromosome Duplication in Saccharomyces cerevisiae.

scientific article published on July 2016

Components and Dynamics of DNA Replication Complexes in S. cerevisiae: Redistribution of MCM Proteins and Cdc45p during S Phase ⬇️

scientific article published on October 3, 1997

Coordination of replication and transcription along a Drosophila chromosome.

scientific article published on December 2004

DNA Replication. Terminating the replisome

scientific article published in Science

DNA replication in eukaryotic cells

scientific article (publication date: 2002)

Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication

scientific article

Drosophila ORC specifically binds to ACE3, an origin of DNA replication control element

scientific article

Eukaryotic origin-dependent DNA replication in vitro reveals sequential action of DDK and S-CDK kinases.

scientific article

Functional Cooperativity Between Transcription Factors UBF1 and SL1 Mediates Human Ribosomal RNA Synthesis ⬇️

scientific article published on September 2, 1988

Genome-wide analysis of re-replication reveals inhibitory controls that target multiple stages of replication initiation

scientific article

Genome-wide distribution of ORC and MCM proteins in S. cerevisiae: high-resolution mapping of replication origins.

scientific article

Genome-wide location and function of DNA binding proteins

scientific article (publication date: 22 December 2000)

Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb MuvB/dREAM complex in proliferating cells

scientific article

Helicase loading at chromosomal origins of replication

scientific article

Initiation of DNA replication in eukaryotic cells

scientific article

Initiation-specific alleles of the Cdc45 helicase-activating protein

scientific article published on 26 March 2019

Interaction of the S-phase cyclin Clb5 with an "RXL" docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch.

scientific article

Interactions between two catalytically distinct MCM subgroups are essential for coordinated ATP hydrolysis and DNA replication

scientific article (publication date: November 2001)

Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila

scientific article

Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7

scientific article published on November 2010

Mechanism and timing of Mcm2-7 ring closure during DNA replication origin licensing.

scientific article published on 13 February 2017

Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases ⬇️

scientific article published on November 1, 2011

Multiple functions for Mcm2-7 ATPase motifs during replication initiation

scientific article published on 31 July 2014

Multiple kinases inhibit origin licensing and helicase activation to ensure reductive cell division during meiosis

scientific article published in February 2018

Nucleosomes influence multiple steps during replication initiation

scientific article published on 21 March 2017

Nucleosomes positioned by ORC facilitate the initiation of DNA replication

scientific article published in January 2001

Polymerases and the replisome: machines within machines.

scientific article

Purification and biochemical characterization of the promoter-specific transcription factor, Sp1

scientific article published in Science

Putting two heads together to unwind DNA.

scientific article

Regulation of origin recognition complex conformation and ATPase activity: differential effects of single-stranded and double-stranded DNA binding

scientific article

Replication origin-flanking roadblocks reveal origin-licensing dynamics and altered sequence dependence

scientific article

Rethinking origin licensing.

scientific article

Separation of DNA Replication from the Assembly of Break-Competent Meiotic Chromosomes ⬇️

scientific article published on May 17, 2012

Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase

scientific article

Single-molecule studies of origin licensing reveal mechanisms ensuring bidirectional helicase loading

scientific article published on 16 April 2015

Subunit organization of Mcm2-7 and the unequal role of active sites in ATP hydrolysis and viability.

scientific article published on 28 July 2008

The B2 element of the Saccharomyces cerevisiae ARS1 origin of replication requires specific sequences to facilitate pre-RC formation ⬇️

scientific article published on December 26, 2001

The dynamics of eukaryotic replication initiation: origin specificity, licensing, and firing at the single-molecule level.

scientific article published on 23 April 2015

The multidomain structure of Orc1p reveals similarity to regulators of DNA replication and transcriptional silencing

scientific article

The origin recognition complex in silencing, cell cycle progression, and DNA replication.

scientific article

The replicon model and eukaryotic chromosomes

scientific article published in 1993

Yeast origin recognition complex functions in transcription silencing and DNA replication

scientific article

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