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List of works by Yit-Heng Chooi

A Multifunctional Monooxygenase XanO4 Catalyzes Xanthone Formation in Xantholipin Biosynthesis via a Cryptic Demethoxylation

scientific article published in April 2016

A chemical ecogenomics approach to understand the roles of secondary metabolites in fungal cereal pathogens

scientific article

A cytochrome P450 serves as an unexpected terpene cyclase during fungal meroterpenoid biosynthesis ⬇️

scientific article

A genome-wide survey of the secondary metabolite biosynthesis genes in the wheat pathogen Parastagonospora nodorum

scientific article

Acquisition and Loss of Secondary Metabolites Shaped the Evolutionary Path of Three Emerging Phytopathogens of Wheat

scientific article published on 01 March 2019

Adding the Lipo to Lipopeptides: Do More with Less ⬇️

scientific article published on August 27, 2010

An in planta-expressed polyketide synthase produces (R)-mellein in the wheat pathogen Parastagonospora nodorum ⬇️

scientific article

Aspergillus hancockii sp. nov., a biosynthetically talented fungus endemic to southeastern Australian soils

scientific article

Biosynthesis of a New Benzazepine Alkaloid Nanangelenin A from Aspergillus nanangensis Involves an Unusual l-Kynurenine-Incorporating NRPS Catalyzing Regioselective Lactamization ⬇️

scientific article published on 31 March 2020

Biosynthesis of a Tricyclo[6.2.2.02,7 ]dodecane System by a Berberine Bridge Enzyme-Like Aldolase

scientific article published on 28 October 2019

Biosynthesis of bioactive natural products from Basidiomycota

scientific article published on 01 January 2019

Biosynthesis of the pyrrolidine protein synthesis inhibitor anisomycin involves novel gene ensemble and cryptic biosynthetic steps.

scientific article published on 3 April 2017

Bipolenins K-N: New sesquiterpenoids from the fungal plant pathogen Bipolaris sorokiniana ⬇️

scientific article published on 26 August 2019

Characterisation and heterologous biosynthesis of burnettiene A, a new polyene-decalin polyketide from Aspergillus burnettii ⬇️

scientific article published on 22 October 2021

Characterization of a Silent Azaphilone Gene Cluster from Aspergillus niger ATCC 1015 Reveals a Hydroxylation-Mediated Pyran-Ring Formation ⬇️

scientific article published on August 24, 2012

Characterization of the Suillus grevillei quinone synthetase GreA supports a nonribosomal code for aromatic α-keto acids

scientific article

Chemical Ecogenomics-Guided Discovery of Phytotoxic α-Pyrones from the Fungal Wheat Pathogen Parastagonospora nodorum ⬇️

scientific article published on 18 September 2018

Chlorinated metabolites from Streptomyces sp. highlight the role of biosynthetic mosaics and superclusters in the evolution of chemical diversity ⬇️

scientific article published on 21 June 2021

Cloning and sequence characterization of a non-reducing polyketide synthase gene from the lichen Xanthoparmelia semiviridis

scientific article

Comparative characterization of fungal anthracenone and naphthacenedione biosynthetic pathways reveals an α-hydroxylation-dependent Claisen-like cyclization catalyzed by a dimanganese thioesterase.

scientific article published on 14 September 2011

Complexity generation in fungal polyketide biosynthesis: a spirocycle-forming P450 in the concise pathway to the antifungal drug griseofulvin.

scientific article published on 9 September 2013

Conglobatins B-E: cytotoxic analogues of the C2-symmetric macrodiolide conglobatin ⬇️

scientific article published on 17 June 2020

Discovery and Heterologous Biosynthesis of the Burnettramic Acids: Rare PKS-NRPS-Derived Bolaamphiphilic Pyrrolizidinediones from an Australian Fungus, Aspergillus burnettii ⬇️

scientific article published on 08 February 2019

Discovery and characterization of a group of fungal polycyclic polyketide prenyltransferases. ⬇️

scientific article published on 25 May 2012

Discovery of brevijanazines from Aspergillus brevijanus reveals the molecular basis for p-nitrobenzoic acid in fungi

Discovery of cryptic polyketide metabolites from dermatophytes using heterologous expression in Aspergillus nidulans ⬇️

scientific article published on 11 June 2013

Efficient Biosynthesis of Fungal Polyketides Containing the Dioxabicyclo-octane Ring System

scientific article published on 4 September 2015

Elucidation of Piericidin A1 biosynthetic locus revealed a thioesterase-dependent mechanism of α-pyridone ring formation

scientific article

Elucidation of the concise biosynthetic pathway of the communesin indole alkaloids. ⬇️

scientific article published on 8 January 2015

Epigenetic genome mining of an endophytic fungus leads to the pleiotropic biosynthesis of natural products ⬇️

scientific article published on 27 May 2015

Functional genomics-guided discovery of a light-activated phytotoxin in the wheat pathogen Parastagonospora nodorum via pathway activation. ⬇️

scientific article

Functional redundancy of necrotrophic effectors - consequences for exploitation for breeding

scientific article published on 8 July 2015

Fungal Dirigent Protein Controls the Stereoselectivity of Multicopper Oxidase-Catalyzed Phenol Coupling in Viriditoxin Biosynthesis

scientific article published on 08 May 2019

Fungal Indole Alkaloid Biosynthesis: Genetic and Biochemical Investigation of the Tryptoquialanine Pathway in Penicillium aethiopicum ⬇️

scientific article published on February 7, 2011

Fungal polyketide synthase product chain-length control by partnering thiohydrolase

scientific article

Generation of complexity in fungal terpene biosynthesis: discovery of a multifunctional cytochrome P450 in the fumagillin pathway

scientific article published on 11 March 2014

Genetic characterization of enzymes involved in the priming steps of oxytetracycline biosynthesis in Streptomyces rimosus

scientific article published on 26 May 2011

Genome Mining of Aspergillus hancockii Unearths Cryptic Polyketide Hancockinone A Featuring a Prenylated 6/6/6/5 Carbocyclic Skeleton ⬇️

scientific article published on 8 November 2021

Genome mining of a prenylated and immunosuppressive polyketide from pathogenic fungi ⬇️

scientific article published on 31 January 2013

Genomics-Driven Discovery of Phytotoxic Cytochalasans Involved in the Virulence of the Wheat Pathogen Parastagonospora nodorum ⬇️

scientific article published on 20 December 2019

Hancockiamides: phenylpropanoid piperazines from Aspergillus hancockii are biosynthesised by a versatile dual single-module NRPS pathway ⬇️

scientific article published on 23 November 2020

Heterologous biosynthesis of elsinochrome A sheds light on the formation of the photosensitive perylenequinone system ⬇️

scientific article published on 22 November 2018

Heterologous expression of cytotoxic sesquiterpenoids from the medicinal mushroom Lignosus rhinocerotis in yeast.

scientific article

Identification and Heterologous Production of a Benzoyl-Primed Tricarboxylic Acid Polyketide Intermediate from the Zaragozic Acid A Biosynthetic Pathway

scientific article published on 13 June 2017

Identification and characterization of the echinocandin B biosynthetic gene cluster from Emericella rugulosa NRRL 11440.

scientific article published on October 2012

Identification of the viridicatumtoxin and griseofulvin gene clusters from Penicillium aethiopicum

scientific article

Involvement of Lipocalin-like CghA in Decalin-Forming Stereoselective Intramolecular [4+2] Cycloaddition.

scientific article published on 11 September 2015

LovG: the thioesterase required for dihydromonacolin L release and lovastatin nonaketide synthase turnover in lovastatin biosynthesis

scientific article published on 07 May 2013

MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration

scientific article published on 9 December 2024

Metabolic engineering for the production of natural products.

scientific article

Minimum Information about a Biosynthetic Gene cluster.

scientific article published on August 2015

Nanangenines: drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensis ⬇️

scientific article published on 05 November 2019

Navigating the fungal polyketide chemical space: from genes to molecules.

scientific article published on 13 September 2012

Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi

scientific article

Panning for gold in mould: can we increase the odds for fungal genome mining?

scientific article

SnPKS19 Encodes the Polyketide Synthase for Alternariol Mycotoxin Biosynthesis in the Wheat Pathogen Parastagonospora nodorum

scientific article published on 29 May 2015

Synthaser: a CD-Search enabled Python toolkit for analysing domain architecture of fungal secondary metabolite megasynth(et)ases

scientific article published on 11 November 2021

The fumagillin biosynthetic gene cluster in Aspergillus fumigatus encodes a cryptic terpene cyclase involved in the formation of β-trans-bergamotene ⬇️

scientific article published on 19 March 2013

The fungal gene cluster for biosynthesis of the antibacterial agent viriditoxin

scientific article published on 01 July 2019

The genome of the Tiger Milk mushroom, Lignosus rhinocerotis, provides insights into the genetic basis of its medicinal properties

scientific article

The global regulator of pathogenesis PnCon7 positively regulates Tox3 effector gene expression through direct interaction in the wheat pathogen Parastagonospora nodorum

scientific article published on 03 May 2018

The identification and deletion of the polyketide synthase-nonribosomal peptide synthase gene responsible for the production of the phytotoxic triticone A/B in the wheat fungal pathogen Pyrenophora tritici-repentis

scientific article published on 21 November 2019

The past, present and future of secondary metabolite research in the Dothideomycetes.

scientific article published on 07 July 2014

Transcriptome Analysis Revealed Highly Expressed Genes Encoding Secondary Metabolite Pathways and Small Cysteine-Rich Proteins in the Sclerotium of Lignosus rhinocerotis

scientific article published on 25 November 2015

Victorin, the host-selective cyclic peptide toxin from the oat pathogen Cochliobolus victoriae, is ribosomally encoded ⬇️

scientific article published on 14 September 2020

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