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List of works by David Meierhofer

A Y2H-seq approach defines the human protein methyltransferase interactome

scientific article

A modular synthetic route to size-defined immunogenic Haemophilus influenzae b antigens is key to the identification of an octasaccharide lead vaccine candidate.

scientific article published on 11 December 2017

Acylcarnitine profiling by low-resolution LC-MS

scientific article published on 15 August 2019

Advantages and Pitfalls of Mass Spectrometry Based Metabolome Profiling in Systems Biology

scientific article

An Impaired Respiratory Electron Chain Triggers Down-regulation of the Energy Metabolism and De-ubiquitination of Solute Carrier Amino Acid Transporters

scientific article published on 6 February 2016

Are Hydroethidine-Based Probes Reliable for Reactive Oxygen Species Detection?

scientific article published on 22 June 2018

Ataxin-2 (Atxn2)-Knock-Out Mice Show Branched Chain Amino Acids and Fatty Acids Pathway Alterations

scientific article published on 5 February 2016

Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism

scientific article published on 26 September 2015

Brain maturation is associated with increasing tissue stiffness and decreasing tissue fluidity

scientific article published on 23 August 2019

Cell autonomous requirement of neurofibromin (Nf1) for postnatal muscle hypertrophic growth and metabolic homeostasis

scientific article published on 19 October 2020

Characterization of Lipid and Lipid Droplet Metabolism in Human HCC.

scientific article published on 27 May 2019

Comprehensive proteomic data sets for studying adipocyte-macrophage cell-cell communication

scientific article

Correction to "integrative analysis of transcriptomics, proteomics, and metabolomics data of white adipose and liver tissue of high-fat diet and rosiglitazone-treated insulin-resistant mice identified pathway alterations and molecular hubs".

scientific article published on 24 February 2015

Decrease of mitochondrial DNA content and energy metabolism in renal cell carcinoma

scientific article published on 4 February 2004

Decreased mitochondrial DNA content drives OXPHOS dysregulation in chromophobe renal cell carcinoma

scientific article published on 21 July 2020

Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome

scientific article published on 26 March 2021

Defining Human Tyrosine Kinase Phosphorylation Networks Using Yeast as an In Vivo Model Substrate.

scientific article published on August 2017

Dnmt1 has de novo activity targeted to transposable elements

scientific article published on 17 June 2021

Efficient Prevention of Neurodegenerative Diseases by Depletion of Starvation Response Factor Ataxin-2.

scientific article

Endocytosis-mediated replenishment of amino acids favors cancer cell proliferation and survival in chromophobe renal cell carcinoma

scientific article published on 28 October 2020

GORAB Missense Mutations Disrupt RAB6 and ARF5 Binding and Golgi Targeting

scientific article published on 22 May 2015

Genetic determinants of steatosis and fibrosis progression in paediatric non-alcoholic fatty liver disease

scientific article published on 21 December 2018

Global Analysis of Ubiquitination

HEPATOKIN1 is a biochemistry-based model of liver metabolism for applications in medicine and pharmacology.

scientific article published on 19 June 2018

Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders

scientific article published on 25 January 2017

Identification and characterization of DNA sequences that prevent glucocorticoid receptor binding to nearby response elements

scientific article published on 25 March 2016

Integrative analysis of transcriptomics, proteomics, and metabolomics data of white adipose and liver tissue of high-fat diet and rosiglitazone-treated insulin-resistant mice identified pathway alterations and molecular hubs

scientific article

Lipoic acid synthetase deficiency causes neonatal-onset epilepsy, defective mitochondrial energy metabolism, and glycine elevation

scientific article published in December 2011

Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma

scientific article published in April 2008

Metabolome and proteome profiling of complex I deficiency induced by rotenone

scientific article published on 12 November 2014

Mitochondrial DNA mutations in renal cell carcinomas revealed no general impact on energy metabolism

scientific article published in January 2006

Multiplex primer extension analysis for rapid detection of major European mitochondrial haplogroups

scientific article

Mutations in Subunits of the Activating Signal Cointegrator 1 Complex Are Associated with Prenatal Spinal Muscular Atrophy and Congenital Bone Fractures

scientific journal article

PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3

scientific article

Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA

scientific article

Platelet transfusion can mimic somatic mtDNA mutations

scientific article published on 01 February 2006

Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation

scientific article published on 2 August 2017

Protein sets define disease states and predict in vivo effects of drug treatment

scientific article published on 11 April 2013

Quantitative Global Proteomics of Yeast PBP1 Deletion Mutants and Their Stress Responses Identifies Glucose Metabolism, Mitochondrial, and Stress Granule Changes

scientific article published on 14 December 2016

Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry

scientific article published on 10 September 2008

Rapid screening of the entire mitochondrial DNA for low-level heteroplasmic mutations.

scientific article

Recurrent De Novo Mutations Affecting Residue Arg138 of Pyrroline-5-Carboxylate Synthase Cause a Progeroid Form of Autosomal-Dominant Cutis Laxa

scientific journal article

Renal oncocytoma characterized by the defective complex I of the respiratory chain boosts the synthesis of the ROS scavenger glutathione

scientific article published on 11 November 2017

SON and SRRM2 are essential for nuclear speckle formation

scientific article published on 23 October 2020

Serial interactome capture of the human cell nucleus

scientific article

Severe depletion of mitochondrial DNA in spinal muscular atrophy

scientific article

Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence

scientific article published on 02 October 2020

Tandem affinity purification combined with mass spectrometry to identify components of protein complexes

scientific article published on January 2008

The long non-coding RNA PARROT is an upstream regulator of c-Myc and affects proliferation and translation.

scientific article published on 25 April 2016

Transcriptomic and proteomic insight into the effects of a defined European mistletoe extract in Ewing sarcoma cells reveals cellular stress responses

scientific article

Transcriptomics assisted proteomic analysis of Nicotiana occidentalis infected by Candidatus Phytoplasma mali strain AT.

scientific article published on 28 July 2014

ρ⁰ Cells Feature De-Ubiquitination of SLC Transporters and Increased Levels and Fluxes of Amino Acids

scientific article published on 20 April 2017

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