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List of works by Ginger Lohr Milne

15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer

scientific journal article

A Prospective Study of Urinary Prostaglandin E2 Metabolite, Helicobacter pylori Antibodies, and Gastric Cancer Risk

scientific article published on 11 April 2017

A metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- mice

scientific article

A phase I trial to determine the optimal biological dose of celecoxib when combined with erlotinib in advanced non-small cell lung cancer

scientific article published on June 2006

A randomized, placebo-controlled, multicenter, biomarker-selected, phase 2 study of apricoxib in combination with erlotinib in patients with advanced non-small-cell lung cancer

scientific article

ASPirin Intervention for the REDuction of colorectal cancer risk (ASPIRED): a study protocol for a randomized controlled trial

scientific article published on February 2017

Altered inflammatory, oxidative, and metabolic responses to exercise in pediatric obesity and type 1 diabetes

scientific article

Amniotic fluid eicosanoids in preterm and term births: effects of risk factors for spontaneous preterm labor

scientific article published on July 2011

Arg287Gln variant of EPHX2 and epoxyeicosatrienoic acids are associated with insulin sensitivity in humans

scientific article

Aspirin therapy and thromboxane biosynthesis in systemic lupus erythematosus

scientific article published in January 2007

Association between urinary prostaglandin E2 metabolite and breast cancer risk: a prospective, case-cohort study of postmenopausal women

scientific article published on May 2013

Association of gain-of-function EPHX2 polymorphism Lys55Arg with acute kidney injury following cardiac surgery

scientific article

Associations between glucosamine and chondroitin supplement use and biomarkers of systemic inflammation

scientific article

Azithromycin Causes a Novel Proarrhythmic Syndrome

scientific article published in April 2017

Biomarker-based phase I dose-escalation, pharmacokinetic, and pharmacodynamic study of oral apricoxib in combination with erlotinib in advanced nonsmall cell lung cancer

scientific article

Changes in Inflammation, Oxidative Stress, Mitochondrial DNA Content after Rosiglitazone in HIV Lipoatrophy

scientific article

Chronic cyclic bladder over distention up-regulates hypoxia dependent pathways

scientific article

Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice

scientific article

Chronic quercetin ingestion and exercise-induced oxidative damage and inflammation

scientific article published in April 2008

Cigarette smoke induces oxidative stress and apoptosis in normal term fetal membranes.

scientific article published in March 2011

Classifying oxidative stress by F2-Isoprostane levels in human disease: The re-imagining of a biomarker

scientific article published on 26 April 2017

Comparison of three oxidative stress biomarkers in a sample of healthy adults

scientific article published on December 2009

Cruciferous vegetable intake is inversely correlated with circulating levels of proinflammatory markers in women

scientific article

Cyclooxygenase inhibition abrogates aeroallergen-induced immune tolerance by suppressing prostaglandin I2 receptor signaling

scientific article

Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer's disease model mice

scientific article published on 13 May 2016

Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system

scientific article

Cyclopentenone isoprostanes are novel bioactive products of lipid oxidation which enhance neurodegeneration

scientific article

Cyclopentenone isoprostanes inhibit the inflammatory response in macrophages

scientific article published on 12 August 2005

Cyclopentenone prostaglandin, 15-deoxy-Delta12,14-PGJ2, is metabolized by HepG2 cells via conjugation with glutathione

scientific article published on 14 September 2007

Cyclosporine A suppresses keratinocyte cell death through MPTP inhibition in a model for skin cancer in organ transplant recipients.

scientific article published on 31 October 2009

Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytes

scientific article

Defining risk factors and presentations of allergic reactions to platelet transfusion

scientific article

Determination of the alpha-tocopherol inhibition rate constant for peroxidation in low-density lipoprotein

scientific article

Deuterium-reinforced polyunsaturated fatty acids protect against atherosclerosis by lowering lipid peroxidation and hypercholesterolemia.

scientific article published on 21 June 2017

Development of oxidative stress by cytochrome P450 induction in rodents is selective for barbiturates and related to loss of pyridine nucleotide-dependent protective systems

scientific journal article

Dietary intake of PUFAs and colorectal polyp risk

scientific article published on 25 January 2012

Differential stem- and progenitor-cell trafficking by prostaglandin E2.

scientific article published on 13 March 2013

Drugs Used in the Treatment of Rheumatoid Arthritis: Relationship between Current Use and Cardiovascular Risk Factors

scientific article published on June 2009

Effect of blueberry ingestion on natural killer cell counts, oxidative stress, and inflammation prior to and after 2.5 h of running

scientific article published on 23 November 2011

Effect of omega-three polyunsaturated fatty acids on inflammation, oxidative stress, and recurrence of atrial fibrillation.

scientific article

Effect of pharmacological lowering of plasma urate on exercise-induced oxidative stress

scientific article published in December 2007

Effect of zileuton and celecoxib on urinary LTE4 and PGE-M levels in smokers

scientific article published on 16 May 2013

Efficacy of paracetamol on patent ductus arteriosus closure may be dose dependent: evidence from human and murine studies.

scientific article

Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the omega-3 polyunsaturated fatty acid docosahexaenoic acid

scientific article

Elevated D-dimer is independently associated with endothelial dysfunction: a cross-sectional study in HIV-infected adults on antiretroviral therapy

scientific article published on 9 August 2012

Elevated Levels of Urinary PGE-M Are Found in Tobacco Users and Indicate a Poor Prognosis for Oral Squamous Cell Carcinoma Patients

scientific article published on 4 April 2016

Elevated levels of urinary prostaglandin e metabolite indicate a poor prognosis in ever smoker head and neck squamous cell carcinoma patients

scientific article published on 20 October 2009

Elevated oxidation of docosahexaenoic acid, 22:6 (n-3), in brain regions of rats undergoing ethanol withdrawal

scientific article published on 26 July 2006

Elevated ratio of urinary metabolites of thromboxane and prostacyclin is associated with adverse cardiovascular events in ADAPT

scientific article

Elevation of prostaglandin E2 in lung cancer patients with digital clubbing

scientific article

Energy Expenditure, Inflammation, and Oxidative Stress in Steady-State Adolescents With Sickle Cell Anemia

scientific article published on 01 February 2007

Essential role of the redox-sensitive kinase p66shc in determining energetic and oxidative status and cell fate in neuronal preconditioning

scientific journal article

Evaluation of pro-inflammatory markers plasma C-reactive protein and urinary prostaglandin-E2 metabolite in colorectal adenoma risk

scientific article

F2-isoprostanes as a biomarker of oxidative stress in the mouse bladder

scientific article

Factors Associated with Multiple Biomarkers of Systemic Inflammation.

scientific article published on 11 January 2016

Fish oil and indomethacin in combination potently reduce dyslipidemia and hepatic steatosis in LDLR(-/-) mice

scientific article

Formation of F-ring Isoprostane-like Compounds (F3-Isoprostanes)in Vivofrom Eicosapentaenoic Acid

scientific article published in Journal of Biological Chemistry

Formation of highly reactive A-ring and J-ring isoprostane-like compounds (A4/J4-neuroprostanes) in vivo from docosahexaenoic acid

scientific article

Formation of highly reactive cyclopentenone isoprostane compounds (A3/J3-isoprostanes) in vivo from eicosapentaenoic acid

scientific article published on 10 February 2008

Formation of prostaglandins E2 and D2 via the isoprostane pathway: a mechanism for the generation of bioactive prostaglandins independent of cyclooxygenase

scientific article published on 13 May 2003

Human biochemistry of the isoprostane pathway

scientific article published on 19 February 2008

Human cytochrome P450 2E1 mutations that alter mitochondrial targeting efficiency and susceptibility to ethanol-induced toxicity in cellular models

scientific article published on 7 March 2013

Hypertrophic osteoarthropathy pathogenesis: a case highlighting the potential role for cyclo-oxygenase-2-derived prostaglandin E2

scientific article published on 01 August 2006

IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging

scientific article

Ibuprofen use during extreme exercise: effects on oxidative stress and PGE2.

scientific article published in July 2007

Identification and analysis of products formed from phospholipids in the free radical oxidation of human low density lipoproteins

scientific article published on 16 November 2004

Identification of intact oxidation products of glycerophospholipids in vitro and in vivo using negative ion electrospray iontrap mass spectrometry

scientific article published on May 2009

Identification of the major urinary metabolite of the highly reactive cyclopentenone isoprostane 15-A(2t)-isoprostane in vivo

scientific article published on 5 May 2005

Impact of hematopoietic cyclooxygenase-1 deficiency on obesity-linked adipose tissue inflammation and metabolic disorders in mice

scientific article published on 27 August 2013

Implications of urine F2-isoprostane metabolite concentration in horses with colic and its potential use as a predictor for surgical intervention

scientific article published on 01 August 2011

In vivo oxidative damage in rats is associated with barbiturate response but not other cytochrome P450 inducers

scientific article published on 26 September 2007

Inactivating mutation in the prostaglandin transporter gene, SLCO2A1, associated with familial digital clubbing, colon neoplasia, and NSAID resistance

scientific article

Increased dietary NaCl induces renal medullary PGE2 production and natriuresis via the EP2 receptor

scientific article published on 16 July 2008

Increased levels of urinary PGE-M, a biomarker of inflammation, occur in association with obesity, aging, and lung metastases in patients with breast cancer

scientific article published on 26 March 2013

Increased oxidative stress and altered substrate metabolism in obese children

scientific article

Increasing F2-isoprostanes in the first month after birth predicts poor respiratory and neurodevelopmental outcomes in very preterm infants

scientific article published on 12 May 2016

Inherited human cPLA(2alpha) deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction

scientific article

Inherited human group IVA cytosolic phospholipase A2 deficiency abolishes platelet, endothelial, and leucocyte eicosanoid generation.

scientific article

Inhibition of the Biosynthesis of Prostaglandin E2 By Low-Dose Aspirin: Implications for Adenocarcinoma Metastasis

scientific article published on 23 August 2016

Interaction between oxidative stress and high-density lipoprotein cholesterol is associated with severity of coronary artery calcification in rheumatoid arthritis

scientific article

Interaction of electrophilic lipid oxidation products with mitochondria in endothelial cells and formation of reactive oxygen species

scientific article published on 30 December 2005

Intra-person variation of urinary biomarkers of oxidative stress and inflammation

scientific article

Intraoperative cerebral oxygenation, oxidative injury, and delirium following cardiac surgery

scientific article published on 27 December 2016

Isoprostane and isofuran lipid mediators accumulate in stored red blood cells and influence platelet function in vitro

scientific article

Isoprostane generation and function

scientific article

Isoprostanes

scientific article published on 28 October 2008

Isoprostanes and related compounds: update 2006.

scientific article published on July 2006

Isotope-reinforced polyunsaturated fatty acids protect mitochondria from oxidative stress

scientific article

Levels of prostaglandin E metabolite and leukotriene E(4) are increased in the urine of smokers: evidence that celecoxib shunts arachidonic acid into the 5-lipoxygenase pathway

scientific article published on 31 March 2009

Lipid profiling of polarized human monocyte-derived macrophages

scientific article

Major metabolite of F2-isoprostane in urine may be a more sensitive biomarker of oxidative stress than isoprostane itself

scientific article published on 3 July 2012

Measurement of F2- isoprostanes and isofurans using gas chromatography-mass spectrometry

scientific article

Menhaden oil decreases high-fat diet-induced markers of hepatic damage, steatosis, inflammation, and fibrosis in obese Ldlr-/- mice

scientific article

Mitochondria-targeted cytochrome P450 2E1 induces oxidative damage and augments alcohol-mediated oxidative stress

scientific article

NADPH:quinone oxidoreductase 1 regulates host susceptibility to ozone via isoprostane generation

scientific article published on 28 December 2012

Natural-source d-α-tocopheryl acetate inhibits oxidant stress and modulates atopic asthma in humans in vivo

scientific article

Neither vaginal nor buccal administration of 800 μg misoprostol alters mucosal and systemic immune activation or the cervicovaginal microbiome: a pilot study.

scientific article

Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.

scientific article

Neurotoxic lipid peroxidation species formed by ischemic stroke increase injury

scientific article published on 19 August 2009

Nonenzymatic free radical-catalyzed generation of 15-deoxy-Δ(12,14)-prostaglandin J₂-like compounds (deoxy-J₂-isoprostanes) in vivo

scientific article

Nonexercise physical activity and inflammatory and oxidative stress markers in women

scientific article published on 29 October 2013

Obesity, age, and oxidative stress in middle-aged and older women

scientific article

Oxidant stress in HIV-infected women from the Women's Interagency HIV Study

scientific article published on January 2009

Oxidative Stress Biomarkers and Incidence of Postoperative Atrial Fibrillation in the Omega-3 Fatty Acids for Prevention of Postoperative Atrial Fibrillation (OPERA) Trial

scientific article

Oxidative stress and matrix metalloproteinase-9 in acute ischemic stroke: the Biomarker Evaluation for Antioxidant Therapies in Stroke (BEAT-Stroke) study

scientific article published on 6 December 2007

Oxidative stress in fibromyalgia and its relationship to symptoms

scientific article published on 17 December 2008

Oxidative stress in relation to diet and physical activity among premenopausal women

scientific article published on 11 October 2016

Oxidative stress in systemic lupus erythematosus: relationship to disease activity and symptoms

scientific article published in January 2007

Oxidative stress measured by urine F2-isoprostane level is associated with prostate cancer

scientific article

Oxidative stress, obesity, and breast cancer risk: results from the Shanghai Women's Health Study

scientific article published on 20 April 2009

Perioperative plasma F(2)-Isoprostane levels correlate with markers of impaired ventilation in infants with single-ventricle physiology undergoing stage 2 surgical palliation on the cardiopulmonary bypass

scientific article published on 12 February 2012

Pharmacodynamics and pharmacokinetics of AM103, a novel inhibitor of 5-lipoxygenase-activating protein (FLAP).

scientific article published on 24 February 2010

Phase III Randomized, Placebo-Controlled, Double-Blind Trial of Celecoxib in Addition to Standard Chemotherapy for Advanced Non-Small-Cell Lung Cancer With Cyclooxygenase-2 Overexpression: CALGB 30801 (Alliance).

scientific article published on 10 May 2017

Phase Ib Randomized, Double-Blinded, Placebo-Controlled, Dose Escalation Study of Polyphenon E in Patients with Barrett's Esophagus

scientific article

Plasma biomarkers of oxidative stress and genetic variants in age-related macular degeneration

scientific article published on 29 October 2011

Preventive effects of NSAIDs, NO-NSAIDs, and NSAIDs plus difluoromethylornithine in a chemically induced urinary bladder cancer model

scientific article published on 17 December 2013

Prostaglandin E2 deficiency uncovers a dominant role for thromboxane A2 in house dust mite-induced allergic pulmonary inflammation

scientific article

Prostaglandins are essential for cervical ripening in LPS-mediated preterm birth but not term or antiprogestin-driven preterm ripening

scientific article published on 20 December 2013

Quantification of F2-isoprostanes as a biomarker of oxidative stress

scientific article published on 01 January 2007

Quantification of F2-isoprostanes in biological fluids and tissues as a measure of oxidant stress

scientific article published in January 2007

Quantification of major urinary metabolites of PGE2 and PGD2 in cystic fibrosis: correlation with disease severity.

scientific article published on 20 June 2013

Randomized phase 2 trial of erlotinib in combination with high-dose celecoxib or placebo in patients with advanced non-small cell lung cancer

scientific article published on 29 May 2015

Randomized trial of glucosamine and chondroitin supplementation on inflammation and oxidative stress biomarkers and plasma proteomics profiles in healthy humans.

scientific article

Recent advances in the biochemistry and clinical relevance of the isoprostane pathway

scientific article

Relationship between total bilirubin and endothelial function, inflammation and oxidative stress in HIV‐infected adults on stable antiretroviral therapy ⬇️

scientific article published on May 25, 2012

Role of inflammation and oxidative stress in atrial fibrillation

scientific article

S1P/S1P2 signaling induces cyclooxygenase-2 expression in Wilms tumor

scientific article published on 20 January 2009

Sex differences in urinary biomarkers of vascular and endothelial function in HIV-infected persons receiving antiretroviral therapy

scientific article published on 14 December 2011

Smoking and red blood cell phospholipid membrane fatty acids

scientific article published on 16 August 2016

Suboptimal inhibition of platelet cyclooxygenase 1 by aspirin in systemic lupus erythematosus: association with metabolic syndrome

scientific article published on February 2014

TISSUE REGENERATION. Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration

scientific article

Tea consumption and oxidative stress: a cross-sectional analysis of 889 premenopausal women from the Sister Study

scientific article published on 20 December 2018

The PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice

scientific article

The cyclopentenone (A2/J2) isoprostanes--unique, highly reactive products of arachidonate peroxidation

scientific article

The cyclopentenone product of lipid peroxidation, 15-A2t-isoprostane, is efficiently metabolized by HepG2 cells via conjugation with glutathione

scientific article

The effect of HIV and HPV coinfection on cervical COX-2 expression and systemic prostaglandin E2 levels

scientific article published on December 2011

The effect of vitamins C and E on biomarkers of oxidative stress depends on baseline level

scientific article published on 16 April 2008

The enteropathy of prostaglandin deficiency

scientific article published on 16 January 2009

The fatty acid oxidation product 15-A3t-isoprostane is a potent inhibitor of NFκB transcription and macrophage transformation

scientific article published on 23 September 2011

The isoprostanes--25 years later

scientific article

The short-term effects of antioxidant and zinc supplements on oxidative stress biomarker levels in plasma: a pilot investigation

scientific article

Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer.

scientific article

Timing of solid food introduction is associated with urinary F2-isoprostane concentrations in childhood

scientific article

Tolerability and pharmacokinetics of delayed-release dimethyl fumarate administered with and without aspirin in healthy volunteers

scientific article published on October 2013

Trans-4-hydroxy-2-hexenal is a neurotoxic product of docosahexaenoic (22:6; n-3) acid oxidation

scientific article

Two pathways for cyclooxygenase-2 protein degradation in vivo

scientific article published on 16 September 2009

Uric acid correlates to oxidation and inflammation in opposite directions in women

scientific article published on June 2015

Urinary PGE-M levels are associated with risk of colorectal adenomas and chemopreventive response to anti-inflammatory drugs

scientific article

Urinary biomarkers of oxidative stress and breast cancer survival

scientific article

Urinary eicosanoid metabolites in HIV-infected women with central obesity switching to raltegravir: an analysis from the women, integrase, and fat accumulation trial.

scientific article

Urinary metabolites of prostanoids and risk of recurrent colorectal adenomas in the Aspirin/Folate Polyp Prevention Study (AFPPS).

scientific article

Urinary prostaglandin E2 metabolite and gastric cancer risk in the Shanghai women's health study

scientific article published on 27 October 2009

Urinary prostaglandin E2 metabolite and risk for colorectal adenoma

scientific article published on 13 December 2011

Urine Eicosanoids in the Metabolic Abnormalities, Telmisartan, and HIV Infection (MATH) Trial

scientific article

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