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List of works by Simon L. Bullock

A cAMP/PKA/Kinesin-1 Axis Promotes the Axonal Transport of Mitochondria in Aging Drosophila Neurons

scientific article published on 20 March 2018

A force-sensitive mutation reveals a non-canonical role for dynein in anaphase progression

scientific article published in 2024

A gene trap insertion reveals that amyloid precursor protein expression is a very early event in murine embryogenesis

scientific article published on 01 July 2001

A simple method for imaging axonal transport in aging neurons using the adult Drosophila wing

scientific article

A stem-loop structure directs oskar mRNA to microtubule minus ends

scientific article

Altered dynein-dependent transport in piRNA pathway mutants

scientific article

Augmenting CRISPR applications in Drosophila with tRNA-flanked sgRNAs.

scientific article published on 5 September 2016

A′-form RNA helices are required for cytoplasmic mRNA transport in Drosophila

scientific article

BIOSAFETY. Safeguarding gene drive experiments in the laboratory

scientific article

Bicaudal-D binds clathrin heavy chain to promote its transport and augments synaptic vesicle recycling

scientific article

Bicaudal-D regulates fragile X mental retardation protein levels, motility, and function during neuronal morphogenesis ⬇️

scientific article published on 5 August 2010

Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to coordinate recruitment of cargos to dynein

scientific article

C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility

scientific article published on 09 April 2021

Cell polarity: Oskar seeks PARtner for a stable relationship

scientific article published in May 2002

Conserved signals and machinery for RNA transport in Drosophila oogenesis and embryogenesis

scientific article

Creating Heritable Mutations in Drosophila with CRISPR-Cas9.

scientific article published in January 2016

DYNC1H1 mutations associated with neurological diseases compromise processivity of dynein-dynactin-cargo adaptor complexes

scientific article published on 14 February 2017

Differential cytoplasmic mRNA localisation adjusts pair-rule transcription factor activity to cytoarchitecture in dipteran evolution

scientific article published on 27 July 2004

Dynein associates with oskar mRNPs and is required for their efficient net plus-end localization in Drosophila oocytes

scientific article

Egalitarian is a selective RNA-binding protein linking mRNA localization signals to the dynein motor

scientific article published on 10 June 2009

Genome-scale requirements for dynein-based transport revealed by a high-content arrayed CRISPR screen

Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4.

scientific article

Guidance of bidirectional motor complexes by mRNA cargoes through control of dynein number and activity

scientific article published in July 2006

In vitro reconstitution of a highly processive recombinant human dynein complex

scientific article (publication date: September 2014)

Inscuteable mRNA localization is dynein-dependent and regulates apicobasal polarity and spindle length in Drosophila neuroblasts

scientific article published on November 2004

Lis1 activates dynein motility by modulating its pairing with dynactin

scientific article published on 27 April 2020

Lissencephaly-1 is a context-dependent regulator of the human dynein complex

scientific article published on 13 April 2017

Lissencephaly-1 promotes the recruitment of dynein and dynactin to transported mRNAs

scientific article

Messengers, motors and mysteries: sorting of eukaryotic mRNAs by cytoskeletal transport ⬇️

scientific article published on October 1, 2011

Phenotypic and molecular insights into spinal muscular atrophy due to mutations in BICD2.

scientific article

RNA-directed activation of cytoplasmic dynein-1 in reconstituted transport RNPs

Recognition of the bcd mRNA localization signal in Drosophila embryos and ovaries

scientific article

Reducing Lissencephaly-1 levels augments mitochondrial transport and has a protective effect in adult Drosophila neurons.

scientific article published on 23 November 2015

Remembering Rosa Beddington--a tribute from her friends and colleagues

scientific article

Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase

scientific journal article

Reply: The p.Ser107Leu in BICD2 is a mutation 'hot spot' causing distal spinal muscular atrophy

scientific article

Single-molecule assays reveal that RNA localization signals regulate dynein–dynactin copy number on individual transcript cargoes ⬇️

scientific article published on February 26, 2012

SnapShot: Subcellular mRNA Localization

scientific article published in March 2017

Specific modification of heparan sulphate is required for normal cerebral cortical development

scientific article

Subcellular mRNA localization in animal cells and why it matters

scientific article

Systematic Evaluation of Drosophila CRISPR Tools Reveals Safe and Robust Alternatives to Autonomous Gene Drives in Basic Research

scientific article published on 20 May 2015

The Drosophila MAST kinase Drop out is required to initiate membrane compartmentalisation during cellularisation and regulates dynein-based transport

scientific article

The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport

scientific article

The influence of dynein processivity control, MAPs, and microtubule ends on directional movement of a localising mRNA.

scientific article published on 15 April 2014

The molecular phenotype of heparan sulfate in the Hs2st-/- mutant mouse

scientific journal article

Translocation of mRNAs by molecular motors: think complex?

scientific article published on 26 January 2007

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