List of works - Giovanni Piccoli

A cell surface biotinylation assay to reveal membrane-associated neuronal cues: Negr1 regulates dendritic arborization

scientific article published on 31 December 2013

A functional role of postsynaptic density-95-guanylate kinase-associated protein complex in regulating Shank assembly and stability to synapses

scientific article

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons

scientific article published on 26 September 2019

Clearance of Rhodopsin(P23H) aggregates requires the ERAD effector VCP.

scientific article published on 25 January 2010

Cryopreservation of Primary Mouse Neurons: The Benefit of Neurostore Cryoprotective Medium.

scientific article published on 22 March 2018

LRRK2 Regulates Voltage-Gated Calcium Channel Function

scientific article published on 23 May 2016

LRRK2 at the presynaptic site: a 16-years perspective

scientific article published on 18 November 2020

LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool

scientific article

LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex

scientific article

LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate

scientific article published on 13 January 2016

LRRK2 phosphorylation level correlates with abnormal motor behaviour in an experimental model of levodopa-induced dyskinesias

scientific article

Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain

scientific article

Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain

scientific article

Leucine-rich repeat kinase 2 phosphorylation on synapsin I regulates glutamate release at pre-synaptic sites

scientific article published on 10 July 2019

Levetiracetam treatment ameliorates LRRK2 pathological mutant phenotype

scientific article published on 27 September 2019

NEGR1 and FGFR2 cooperatively regulate cortical development and core behaviours related to autism disorders in mice.

scientific article published in September 2018

Nanolipid-Trehalose Conjugates and Nano-Assemblies as Putative Autophagy Inducers

scientific article published on 20 August 2019

Organization of the presynaptic active zone by ERC2/CAST1-dependent clustering of the tandem PDZ protein syntenin-1.

scientific article

PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2.

scientific article published on 14 December 2017

Parkin Interacts with Apoptosis-Inducing Factor and Interferes with Its Translocation to the Nucleus in Neuronal Cells ⬇️

scientific article published on 11 February 2019

Protein fingerprints of cultured CA3-CA1 hippocampal neurons: comparative analysis of the distribution of synaptosomal and cytosolic proteins

scientific article

Proteomic analysis of activity-dependent synaptic plasticity in hippocampal neurons.

scientific article

Synaptic activity controls dendritic spine morphology by modulating eEF2-dependent BDNF synthesis

scientific journal article

Synaptic dysfunction in Parkinson's disease.

scientific article published on January 2012

TIRFM and pH-sensitive GFP-probes to evaluate neurotransmitter vesicle dynamics in SH-SY5Y neuroblastoma cells: cell imaging and data analysis

scientific article

The IgLON Family Member Negr1 Promotes Neuronal Arborization Acting as Soluble Factor via FGFR2.

scientific article

The LRRK2 G2385R variant is a partial loss-of-function mutation that affects synaptic vesicle trafficking through altered protein interactions.

scientific article

The LRRK2 N-terminal domain influences vesicle trafficking: impact of the E193K variant

scientific article published on 02 March 2020

The LRRK2 Variant E193K Prevents Mitochondrial Fission Upon MPP+ Treatment by Altering LRRK2 Binding to DRP1.

scientific article published on 28 February 2018

The fragile X mental retardation protein-RNP granules show an mGluR-dependent localization in the post-synaptic spines

scientific journal article

The pathogenic LRRK2 R1441C mutation induces specific deficits modeling the prodromal phase of Parkinson's disease in the mouse

scientific article published on 30 May 2017

List of works by Giovanni Piccoli

A cell surface biotinylation assay to reveal membrane-associated neuronal cues: Negr1 regulates dendritic arborization

A functional role of postsynaptic density-95-guanylate kinase-associated protein complex in regulating Shank assembly and stability to synapses

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons

Clearance of Rhodopsin(P23H) aggregates requires the ERAD effector VCP.

Cryopreservation of Primary Mouse Neurons: The Benefit of Neurostore Cryoprotective Medium.

LRRK2 Regulates Voltage-Gated Calcium Channel Function

LRRK2 at the presynaptic site: a 16-years perspective

LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool

LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex

LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate

LRRK2 phosphorylation level correlates with abnormal motor behaviour in an experimental model of levodopa-induced dyskinesias

Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain

Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain

Leucine-rich repeat kinase 2 phosphorylation on synapsin I regulates glutamate release at pre-synaptic sites

Levetiracetam treatment ameliorates LRRK2 pathological mutant phenotype

NEGR1 and FGFR2 cooperatively regulate cortical development and core behaviours related to autism disorders in mice.

Nanolipid-Trehalose Conjugates and Nano-Assemblies as Putative Autophagy Inducers

Organization of the presynaptic active zone by ERC2/CAST1-dependent clustering of the tandem PDZ protein syntenin-1.

PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2.

Parkin Interacts with Apoptosis-Inducing Factor and Interferes with Its Translocation to the Nucleus in Neuronal Cells ⬇️

Protein fingerprints of cultured CA3-CA1 hippocampal neurons: comparative analysis of the distribution of synaptosomal and cytosolic proteins

Proteomic analysis of activity-dependent synaptic plasticity in hippocampal neurons.

Synaptic activity controls dendritic spine morphology by modulating eEF2-dependent BDNF synthesis

Synaptic dysfunction in Parkinson's disease.

TIRFM and pH-sensitive GFP-probes to evaluate neurotransmitter vesicle dynamics in SH-SY5Y neuroblastoma cells: cell imaging and data analysis

The IgLON Family Member Negr1 Promotes Neuronal Arborization Acting as Soluble Factor via FGFR2.

The LRRK2 G2385R variant is a partial loss-of-function mutation that affects synaptic vesicle trafficking through altered protein interactions.

The LRRK2 N-terminal domain influences vesicle trafficking: impact of the E193K variant

The LRRK2 Variant E193K Prevents Mitochondrial Fission Upon MPP+ Treatment by Altering LRRK2 Binding to DRP1.

The fragile X mental retardation protein-RNP granules show an mGluR-dependent localization in the post-synaptic spines

The pathogenic LRRK2 R1441C mutation induces specific deficits modeling the prodromal phase of Parkinson's disease in the mouse