Search filters

Authors whose works are in public domain in at least one jurisdiction

List of works by Stan F van de Graaf

An Exon-Specific Small Nuclear U1 RNA (ExSpeU1) Improves Hepatic OTC Expression in a Splicing-Defective spf/ash Mouse Model of Ornithine Transcarbamylase Deficiency

scientific article published on 19 November 2020

Analysis of aberrant pre-messenger RNA splicing resulting from mutations in ATP8B1 and efficient in vitro rescue by adapted U1 small nuclear RNA.

scientific article published on 23 February 2015

Annexin A11 is targeted by IgG4 and IgG1 autoantibodies in IgG4-related disease.

scientific article

Autophagy - another piece of the puzzle towards understanding primary biliary cirrhosis?

scientific article published on 01 April 2014

Bile Acid Uptake Transporters as Targets for Therapy.

scientific article published on March 2017

Biliverdin Reductase inhibitors did not improve severe unconjugated hyperbilirubinemia in vivo

scientific article published on 10 May 2017

Biochemical and cellular functions of P4 ATPases.

scientific article published on October 2010

Blocking Sodium-Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice

scientific article published on 13 August 2019

Calnexin Depletion by Endoplasmic Reticulum Stress During Cholestasis Inhibits the Na+-Taurocholate Cotransporting Polypeptide

scientific article published on 23 October 2018

Clinical and genetic analysis of a family with two rare reflex epilepsies

scientific article published on 06 April 2015

Current and future therapies for inherited cholestatic liver diseases.

scientific article published on February 2017

Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60.

scientific article

Familial cholestasis: progressive familial intrahepatic cholestasis, benign recurrent intrahepatic cholestasis and intrahepatic cholestasis of pregnancy.

scientific article published on October 2010

Folding defects in P-type ATP 8B1 associated with hereditary cholestasis are ameliorated by 4-phenylbutyrate.

scientific article published in January 2010

Fucosyltransferase 2: a genetic risk factor for primary sclerosing cholangitis and Crohn's disease--a comprehensive review

scientific article published on June 2015

Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex

scientific article

Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice

scientific article published on 12 May 2017

Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases

scientific article

Homo- and hetero-dimeric architecture of the human liver Na⁺-dependent taurocholate co-transporting protein

scientific article published on 01 February 2012

Identification of BSPRY as a novel auxiliary protein inhibiting TRPV5 activity.

scientific article published on January 2006

Identification of FDA-approved drugs targeting the Farnesoid X Receptor

scientific article published on 18 February 2019

IgG4-associated cholangitis.

scientific article published on 14 July 2014

IgG4-associated cholangitis: a comprehensive review

scientific article

Immunoglobulin G4(+) B-cell receptor clones distinguish immunoglobulin G 4-related disease from primary sclerosing cholangitis and biliary/pancreatic malignancies.

scientific article published on 25 March 2016

Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+) -taurocholate cotransporting polypeptide knockout mice.

scientific article

Interaction of the epithelial Ca2+ channels TRPV5 and TRPV6 with the intestine- and kidney-enriched PDZ protein NHERF4.

scientific article published on 25 March 2006

Intestinal Farnesoid X Receptor Activation by Pharmacologic Inhibition of the Organic Solute Transporter α-β.

scientific article

Knockout of the primary sclerosing cholangitis-risk gene Fut2 causes liver disease in mice

scientific article published on 5 January 2017

Molecular identification of the apical Ca2+ channel in 1, 25-dihydroxyvitamin D3-responsive epithelia

scientific article published in March 1999

Monitoring bile acid transport in single living cells using a genetically encoded Förster resonance energy transfer sensor.

scientific article published on 8 January 2013

Mutational analysis of ATP8B1 in patients with chronic pancreatitis

scientific article

N-Glycosylation of the Na+-Taurocholate Cotransporting Polypeptide (NTCP) Determines Its Trafficking and Stability and Is Required for Hepatitis B Virus Infection.

scientific article

Natural killer T cells in adipose tissue prevent insulin resistance

scientific article

On the role of IgG4 in inflammatory conditions: lessons for IgG4-related disease.

scientific article

Quantifying stickiness: thermodynamic characterization of intramolecular domain interactions to guide the design of förster resonance energy transfer sensors

scientific article published on 26 September 2014

Real Time Monitoring of Intracellular Bile Acid Dynamics Using a Genetically Encoded FRET-based Bile Acid Sensor

scientific article published on 4 January 2016

Reduced hepatitis B and D viral entry using clinically applied drugs as novel inhibitors of the bile acid transporter NTCP.

scientific article

Regulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase isoforms SGK1 and SGK3 expressed in Xenopus oocytes

scientific article published in January 2004

Regulation of the epithelial Ca2+ channels TRPV5 and TRPV6 by 1alpha,25-dihydroxy Vitamin D3 and dietary Ca2+.

scientific article published in May 2004

Reply: The role of mEH, NTCP and OATP in hepatic sodium-dependent bile acid transport.

scientific article published on 6 December 2017

Requirement of PDZ domains for the stimulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase SGK1

scientific article

Rescue of defective ATP8B1 trafficking by CFTR correctors as a therapeutic strategy for familial intrahepatic cholestasis.

scientific article

Role of the Bile Acid Transporter SLC10A1 in Liver Targeting of the Lipid-Lowering Thyroid Hormone Analog Eprotirome

scientific article

Targeting the four pillars of enterohepatic bile salt cycling; lessons from genetics and pharmacology

scientific article published on 22 November 2020

The Lipid Raft Component Stomatin Interacts with the Na+ Taurocholate Cotransporting Polypeptide (NTCP) and Modulates Bile Salt Uptake

scientific article published on 16 April 2020

The NTCP-inhibitor Myrcludex B: Effects on Bile Acid Disposition and Tenofovir Pharmacokinetics.

scientific article published on 24 May 2017

The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction

scientific article published in March 2018

Paulina is supported by:

About Paulina

Help