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List of works by Matthias Trost

A Dual Role for FADD in Human Precursor T-Cell Neoplasms

scientific article published in 2022

A MALDI-TOF assay identifies nilotinib as an inhibitor of inflammation in acute myeloid leukaemia

A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia

scientific article published in 2022

A combination of SILAC and nucleotide acyl phosphate labelling reveals unexpected targets of the Rsk inhibitor BI-D1870.

scientific article published on February 2014

A crucial role for β2 integrins in podosome formation, dynamics and Toll-like-receptor-signaled disassembly in dendritic cells

scientific article

A fast and sensitive absolute quantification assay for the detection of SARS-CoV□2 peptides using Parallel Reaction Monitoring Mass Spectrometry

A holin and an endopeptidase are essential for chitinolytic protein secretion in Serratia marcescens

scientific article

A membrane-depolarising toxin substrate of the Staphylococcus aureus Type VII protein secretion system targets eukaryotes and bacteria

A membrane-depolarizing toxin substrate of the Staphylococcus aureus type VII secretion system mediates intraspecies competition

scientific article published on 07 August 2020

A mutant O-GlcNAcase enriches Drosophila developmental regulators.

scientific article published on 12 June 2017

A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation

scientific article published on 22 October 2018

Activation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathway

scientific article

Activity-dependent bulk endocytosis proteome reveals a key presynaptic role for the monomeric GTPase Rab11

article published in the Proceedings of the National Academy of Sciences of the United States of America

Anaerobic adaptation in Pseudomonas aeruginosa: definition of the Anr and Dnr regulons

scientific journal article

Assessing the Phagosome Proteome by Quantitative Mass Spectrometry

scientific article published in January 2017

Author Correction: A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation

scientific article published on 01 November 2019

Author Correction: c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis

scientific article published on 10 December 2020

Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation.

scientific article

BtuB TonB-dependent transporters and BtuG surface lipoproteins form stable complexes for vitamin B 12 uptake in gut Bacteroides

Control of synaptic vesicle release probability via VAMP4 targeting to endolysosomes

Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation

scientific article published on 8 August 2016

High-resolution quantitative proteome analysis reveals substantial differences between phagosomes of RAW 264.7 and bone marrow derived macrophages

scientific article published on 12 December 2014

Hydrophilic strong anion exchange (hSAX) chromatography for highly orthogonal peptide separation of complex proteomes

scientific article

Hydrophilic strong anion exchange chromatography for proteomics: what's the future outlook?

scientific article published in September 2013

IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid

scientific article

Identifying Inhibitors of Inflammation: A Novel High-Throughput MALDI-TOF Screening Assay for Salt-Inducible Kinases (SIKs)

Inhibiting Multiple Deubiquitinases to Reduce Androgen Receptor Expression in Prostate Cancer Cells

scientific article published in Scientific Reports

Inhibition of USP10 induces degradation of oncogenic FLT3.

scientific article

Isolation and Western Blotting of Latex-Bead Phagosomes to Track Phagosome Maturation

scientific article published in January 2017

Killing with proficiency: Integrated post-translational regulation of an offensive Type VI secretion system

scholarly article published by Jun Jie Wong in 2018

LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages

scientific article

Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a

scientific article

Macrophage Phosphoproteome Analysis Reveals MINCLE-dependent and -independent Mycobacterial Cord Factor Signaling

scientific article published on 11 January 2019

Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation

scientific article published on 15 March 2021

Mass spectrometry techniques for studying the ubiquitin system

scientific article

Molecular characterization of the evolution of phagosomes

scientific article

Molecular dissection of the eukaryotic initiation factor 4E (eIF4E) export-competent RNP

scientific article

Outer membrane utilisomes mediate oligosaccharide uptake in gut Bacteroidetes

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

scientific article

Patterns, Receptors, and Signals: Regulation of Phagosome Maturation

scientific article

Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1.

scientific article published on 15 October 2015

Phosphoproteomic screening identifies physiological substrates of the CDKL5 kinase

scientific article published on 28 September 2018

Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases

scientific journal article

Phosphoproteomics reveals that the hVPS34 regulated SGK3 kinase specifically phosphorylates endosomal proteins including Syntaxin-7, Syntaxin-12, RFIP4 and WDR44

scientific article published on 01 October 2019

Phosphoproteomics reveals that the hVPS34 regulated SGK3 kinase specifically phosphorylates endosomal proteins including Syntaxin-7, Syntaxin-12, RFIP4 and WDR44

Posttranslational regulation of self-renewal capacity: insights from proteome and phosphoproteome analyses of stem cell leukemia

scientific article published on 16 July 2012

Profiling embryonic stem cell differentiation by MALDI TOF mass spectrometry: development of a reproducible and robust sample preparation workflow

scientific article published on 01 October 2019

Protein kinase D2 is a digital amplifier of T cell receptor-stimulated diacylglycerol signaling in naïve CD8⁺ T cells

scientific article published on 21 October 2014

Proteomic identification of novel secreted antibacterial toxins of the Serratia marcescens type VI secretion system.

scientific article published on 09 July 2013

Proteomics characterisation of the L929 cell supernatant and its role in BMDM differentiation

Quantitative proteome analysis of temporally resolved phagosomes following uptake via key phagocytic receptors

scientific article published on 9 March 2015

Quantitative proteomics reveals that only a subset of the endoplasmic reticulum contributes to the phagosome.

scientific article

Regulation of phagosome functions by post-translational modifications: a new paradigm

scientific article published on 24 November 2018

Reproducible automated phosphopeptide enrichment using magnetic TiO2 and Ti-IMAC.

scientific article published on 2 October 2014

Screening of DUB activity and specificity by MALDI-TOF mass spectrometry

scientific article

Spatiotemporal changes of the phagosomal proteome in dendritic cells in response to LPS stimulation

scientific article published on 26 February 2019

Stepwise rotation of the γ-subunit of EF o F 1 -ATP synthase during ATP synthesis: a single-molecule FRET approach

Subcellular phosphoproteomics

scientific article

Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity.

scientific article published on 13 July 2016

TPL-2 kinase induces phagosome acidification to promote macrophage killing of bacteria

scientific article published on 21 April 2021

Technical Report: Targeted Proteomic Analysis Reveals Enrichment of Atypical Ubiquitin Chains in Contractile Murine Tissues

The E3 ubiquitin ligase RNF115 regulates phagosome maturation and host response to bacterial infection

scholarly article

The E3 ubiquitin ligase RNF115 regulates phagosome maturation and host response to bacterial infection

The MALDI TOF E2/E3 ligase assay as an universal tool for drug discovery in the ubiquitin pathway

The MALDI-TOF E2/E3 Ligase Assay as Universal Tool for Drug Discovery in the Ubiquitin Pathway

scientific article published on 12 July 2018

The Type 9 Secretion System enables sharing of fungal mannan by human gut Bacteroides

The type VI secretion system deploys antifungal effectors against microbial competitors

scientific article published on 23 July 2018

Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib

scientific article published on 18 April 2018

Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib

Triggering MSR1 promotes JNK-mediated inflammation in IL-4 activated macrophages

Triggering MSR1 promotes JNK‐mediated inflammation in IL‐4‐activated macrophages

scientific article

UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome

scientific article published on 27 July 2016

USP7 small-molecule inhibitors interfere with ubiquitin binding

scientific article published on 18 October 2017

Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers

scientific article published in March 2015

Unanchored tri-NEDD8 inhibits PARP-1 to protect from oxidative stress-induced cell death

VgrG and PAAR Proteins Define Distinct Versions of a Functional Type VI Secretion System

scientific article

c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis

scientific article published on 09 November 2020

mTORC1 and CK2 coordinate ternary and eIF4F complex assembly

scientific article published on 4 April 2016