List of works - Claudia Chiodoni

Accelerated dendritic-cell migration and T-cell priming in SPARC-deficient mice

scientific article

Activated d16HER2 homodimers and SRC kinase mediate optimal efficacy for trastuzumab

scientific article published on 27 August 2014

Amount of interleukin 12 available at the tumor site is critical for tumor regression.

scientific article published in June 1996

Antitumor effect of interleukin (IL)-12 in the absence of endogenous IFN-gamma: a role for intrinsic tumor immunogenicity and IL-15.

scientific article

CD99 triggering in Ewing sarcoma delivers a lethal signal through p53 pathway reactivation and cooperates with doxorubicin

scientific article published on 11 December 2014

Cancer immunotherapy based on killing of Salmonella-infected tumor cells

scientific article published in May 2005

Cytokine gene transduction in tumor cells: interleukin (IL)-2 or IL-4 gene transfer in human melanoma cells

article

Dendritic cells infiltrating tumors cotransduced with granulocyte/macrophage colony-stimulating factor (GM-CSF) and CD40 ligand genes take up and present endogenous tumor-associated antigens, and prime naive mice for a cytotoxic T lymphocyte respons

scientific article

Expression levels of insulin receptor substrate-1 modulate the osteoblastic differentiation of mesenchymal stem cells and osteosarcoma cells

scientific article published on 20 January 2014

HIV/gp120 and PMA/ionomycin induced apoptosis but not activation induced cell death require PKC for Fas-L upregulation

article

Healthy and tumoral tissue resistivity in wild-type and sparc-/- animal models.

scientific article

Human melanoma-reactive CD4+ and CD8+ CTL clones resist Fas ligand-induced apoptosis and use Fas/Fas ligand-independent mechanisms for tumor killing ⬇️

scientific article published on August 1, 1998

Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial-Stromal Tumors by Targeting PDGFR-β.

scientific article published on 15 December 2016

Immune Checkpoint Ligand Reverse Signaling: Looking Back to Go Forward in Cancer Therapy.

scientific article published on 4 May 2019

In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity.

scientific article published on January 2004

Infiltrating mast cell-mediated stimulation of estrogen receptor activity in breast cancer cells promotes the luminal phenotype

scientific article published on 16 March 2020

Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion

scientific article published on 10 October 2012

Interferon gamma-independent rejection of interleukin 12-transduced carcinoma cells requires CD4+ T cells and Granulocyte/Macrophage colony-stimulating factor

scientific article published on July 1998

Interleukin-12 production by leukemia-derived dendritic cells counteracts the inhibitory effect of leukemic microenvironment on T cells

article

Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis

scientific article

Matricellular proteins tune myeloid-derived suppressor cell recruitment and function in breast cancer

scientific article published on February 2017

Matricellular proteins: from homeostasis to inflammation, cancer, and metastasis

scientific article published on June 2010

Mesenchymal Transition of High-Grade Breast Carcinomas Depends on Extracellular Matrix Control of Myeloid Suppressor Cell Activity

scientific article published in September 2016

Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo

scientific article

Myeloid cell expansion elicited by the progression of spontaneous mammary carcinomas in c-erbB-2 transgenic BALB/c mice suppresses immune reactivity

scientific article published on 15 May 2003

Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity

scientific article

Nucleofection is an efficient nonviral transfection technique for human bone marrow-derived mesenchymal stem cells

scientific article

Oncogene-driven intrinsic inflammation induces leukocyte production of tumor necrosis factor that critically contributes to mammary carcinogenesis

scientific article published on 5 October 2010

Osteopontin shapes immunosuppression in the metastatic niche

scientific article

Pathobiological implications of the d16HER2 splice variant for stemness and aggressiveness of HER2-positive breast cancer

scientific article

Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody

scientific article

SOCS2 Controls Proliferation and Stemness of Hematopoietic Cells under Stress Conditions and Its Deregulation Marks Unfavorable Acute Leukemias

scientific article published on 9 April 2015

SPARC oppositely regulates inflammation and fibrosis in bleomycin-induced lung damage

scientific article published on 11 October 2011

Stromal SPARC contributes to the detrimental fibrotic changes associated with myeloproliferation whereas its deficiency favors myeloid cell expansion

scientific article published on 5 September 2012

Stromal niche communalities underscore the contribution of the matricellular protein SPARC to B-cell development and lymphoid malignancies

scientific article published on 5 June 2014

Suppression of invasion and metastasis of triple-negative breast cancer lines by pharmacological or genetic inhibition of slug activity

scientific article

TNF-Related Apoptosis-Inducing Ligand (TRAIL)-Armed Exosomes Deliver Proapoptotic Signals to Tumor Site

scientific article published on 4 March 2016

The ins and outs of osteopontin

scientific article

The matricellular protein SPARC supports follicular dendritic cell networking toward Th17 responses

article

Transcriptional Profiles and Stromal Changes Reveal Bone Marrow Adaptation to Early Breast Cancer in Association with Deregulated Circulating microRNAs

scientific article published on 27 November 2019

Triggering CD40 on endothelial cells contributes to tumor growth

scientific article

Ultrasound-guided intra-tumor injection of combined immunotherapy cures mice from orthotopic prostate cancer

scientific article published on 18 October 2013

WNT signaling modulates PD-L1 expression in the stem cell compartment of triple-negative breast cancer

scientific article published on 31 January 2019

cIAP1 regulates the EGFR/Snai2 axis in triple-negative breast cancer cells.

scientific article published on 19 April 2018

List of works by Claudia Chiodoni

Accelerated dendritic-cell migration and T-cell priming in SPARC-deficient mice

Activated d16HER2 homodimers and SRC kinase mediate optimal efficacy for trastuzumab

Amount of interleukin 12 available at the tumor site is critical for tumor regression.

Antitumor effect of interleukin (IL)-12 in the absence of endogenous IFN-gamma: a role for intrinsic tumor immunogenicity and IL-15.

CD99 triggering in Ewing sarcoma delivers a lethal signal through p53 pathway reactivation and cooperates with doxorubicin

Cancer immunotherapy based on killing of Salmonella-infected tumor cells

Cytokine gene transduction in tumor cells: interleukin (IL)-2 or IL-4 gene transfer in human melanoma cells

Dendritic cells infiltrating tumors cotransduced with granulocyte/macrophage colony-stimulating factor (GM-CSF) and CD40 ligand genes take up and present endogenous tumor-associated antigens, and prime naive mice for a cytotoxic T lymphocyte respons

Expression levels of insulin receptor substrate-1 modulate the osteoblastic differentiation of mesenchymal stem cells and osteosarcoma cells

HIV/gp120 and PMA/ionomycin induced apoptosis but not activation induced cell death require PKC for Fas-L upregulation

Healthy and tumoral tissue resistivity in wild-type and sparc-/- animal models.

Human melanoma-reactive CD4+ and CD8+ CTL clones resist Fas ligand-induced apoptosis and use Fas/Fas ligand-independent mechanisms for tumor killing ⬇️

Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial-Stromal Tumors by Targeting PDGFR-β.

Immune Checkpoint Ligand Reverse Signaling: Looking Back to Go Forward in Cancer Therapy.

In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity.

Infiltrating mast cell-mediated stimulation of estrogen receptor activity in breast cancer cells promotes the luminal phenotype

Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion

Interferon gamma-independent rejection of interleukin 12-transduced carcinoma cells requires CD4+ T cells and Granulocyte/Macrophage colony-stimulating factor

Interleukin-12 production by leukemia-derived dendritic cells counteracts the inhibitory effect of leukemic microenvironment on T cells

Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis

Matricellular proteins tune myeloid-derived suppressor cell recruitment and function in breast cancer

Matricellular proteins: from homeostasis to inflammation, cancer, and metastasis

Mesenchymal Transition of High-Grade Breast Carcinomas Depends on Extracellular Matrix Control of Myeloid Suppressor Cell Activity

Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo

Myeloid cell expansion elicited by the progression of spontaneous mammary carcinomas in c-erbB-2 transgenic BALB/c mice suppresses immune reactivity

Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity

Nucleofection is an efficient nonviral transfection technique for human bone marrow-derived mesenchymal stem cells

Oncogene-driven intrinsic inflammation induces leukocyte production of tumor necrosis factor that critically contributes to mammary carcinogenesis

Osteopontin shapes immunosuppression in the metastatic niche

Pathobiological implications of the d16HER2 splice variant for stemness and aggressiveness of HER2-positive breast cancer

Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody

SOCS2 Controls Proliferation and Stemness of Hematopoietic Cells under Stress Conditions and Its Deregulation Marks Unfavorable Acute Leukemias

SPARC oppositely regulates inflammation and fibrosis in bleomycin-induced lung damage

Stromal SPARC contributes to the detrimental fibrotic changes associated with myeloproliferation whereas its deficiency favors myeloid cell expansion

Stromal niche communalities underscore the contribution of the matricellular protein SPARC to B-cell development and lymphoid malignancies

Suppression of invasion and metastasis of triple-negative breast cancer lines by pharmacological or genetic inhibition of slug activity

TNF-Related Apoptosis-Inducing Ligand (TRAIL)-Armed Exosomes Deliver Proapoptotic Signals to Tumor Site

The ins and outs of osteopontin

The matricellular protein SPARC supports follicular dendritic cell networking toward Th17 responses

Transcriptional Profiles and Stromal Changes Reveal Bone Marrow Adaptation to Early Breast Cancer in Association with Deregulated Circulating microRNAs

Triggering CD40 on endothelial cells contributes to tumor growth

Ultrasound-guided intra-tumor injection of combined immunotherapy cures mice from orthotopic prostate cancer

WNT signaling modulates PD-L1 expression in the stem cell compartment of triple-negative breast cancer

cIAP1 regulates the EGFR/Snai2 axis in triple-negative breast cancer cells.