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List of works by Francisco Corzana

A Double Diastereoselective Michael-Type Addition as an Entry to Conformationally Restricted Tn Antigen Mimics

scientific article published on 14 October 2013

A dynamic combinatorial approach for the analysis of weak carbohydrate/aromatic complexes: dissecting facial selectivity in CH/π stacking interactions.

scientific article published on 25 February 2013

A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2.

scientific article published on 8 February 2016

A simple NMR analysis of the protonation equilibrium that accompanies aminoglycoside recognition: dramatic alterations in the neomycin-B protonation state upon binding to a 23-mer RNA aptamer.

scientific article published on 23 October 2006

A simple structural-based approach to prevent aminoglycoside inactivation by bacterial defense proteins. Conformational restriction provides effective protection against neomycin-B nucleotidylation by ANT4.

scientific article published in June 2005

A thorough experimental study of CH/π interactions in water: quantitative structure-stability relationships for carbohydrate/aromatic complexes

scientific article published on 30 July 2015

Accurate Calculation of Chemical Shifts in Highly Dynamic H2@C60through an Integrated Quantum Mechanics/Molecular Dynamics Scheme

article

Antimicrobial peptides and their superior fluorinated analogues: structure-activity relationships as revealed by NMR spectroscopy and MD calculations.

scientific article

Asymmetric hetero Diels-Alder as an access to carbacephams.

scientific article published in January 2002

Bifunctional Chiral Dehydroalanines for Peptide Coupling and Stereoselective S-Michael Addition.

scientific article published in June 2016

Bioorthogonal Self-Immolative Linker Based on Grob Fragmentation

scientific article published in 2021

Cell-Penetrating Peptides Containing Fluorescent d -Cysteines

scientific article published on 8 May 2018

Chemical Interrogation of Drug/RNA Complexes: From Chemical Reactivity to Drug Design

scientific article published on 07 February 2013

Chemo- and Regioselective Lysine Modification on Native Proteins.

scientific article published on 8 March 2018

Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation

scientific article published on 5 December 2017

Chondroitin Sulfate Tetrasaccharides: Synthesis, Three-Dimensional Structure and Interaction with Midkine

scientific article published on 19 January 2016

Conformational Behavior of d-Lyxose in Gas and Solution Phases by Rotational and NMR Spectroscopies

scientific article published on 04 June 2019

Conformational analysis of 2-substituted cyclobutane-alpha-amino acid derivatives. A synergistic experimental and computational study

scientific article published in March 2006

Conformational analysis of N-Boc-N,O-isopropylidene-α-serinals. A combined DFT and NMR study

Conformational effects of the non-natural alpha-methylserine on small peptides and glycopeptides.

scientific article published in December 2009

Conformational preferences of chiral acyclic homooligomeric β(2,2)-peptides

scientific article published on 01 January 2014

Conformationally-locked C-glycosides: tuning aglycone interactions for optimal chaperone behaviour in Gaucher fibroblasts

scientific article published in 2016

Conformations of the iduronate ring in short heparin fragments described by time-averaged distance restrained molecular dynamics.

scientific article

Cyclobutane amino acid analogues of furanomycin obtained by a formal [2 + 2] cycloaddition strategy promoted by methylaluminoxane

scientific article published in February 2010

Cyclohexane ring as a tool to select the presentation of the carbohydrate moiety in glycosyl amino acids

scientific article published on 01 March 2012

Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody

scientific article

Design of α-S-Neoglycopeptides Derived from MUC1 with a Flexible and Solvent-Exposed Sugar Moiety

scientific article

Detection of tumor-associated glycopeptides by lectins: the peptide context modulates carbohydrate recognition

scientific article

Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation.

scientific article published on 5 May 2015

Effect of beta-O-glucosylation on L-Ser and L-Thr diamides: a bias toward alpha-helical conformations.

scientific article

Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents

scientific article published on 01 January 2019

Engineering O-Glycosylation Points in Non-extended Peptides: Implications for the Molecular Recognition of Short Tumor-Associated Glycopeptides

scientific article published on 08 February 2011

Enhanced Permeability and Binding Activity of Isobutylene-Grafted Peptides.

scientific article published on 3 November 2017

Exploiting structure-activity relationships of QS-21 in the design and synthesis of streamlined saponin vaccine adjuvants

scientific article published on 01 January 2020

Exploring the use of conformationally locked aminoglycosides as a new strategy to overcome bacterial resistance

scientific article

Finding the Right Candidate for the Right Position: A Fast NMR-Assisted Combinatorial Method for Optimizing Nucleic Acids Binders.

scientific article

Frontispiece: Site-Selective Modification of Proteins with Oxetanes

Fucosyltransferase-specific inhibition <i>via</i> next generation of fucose mimetics

scientific article published on 07 January 2021

Identification of a secondary binding site in human macrophage galactose-type lectin by microarray studies: Implications for the molecular recognition of its ligands

scientific article published on 30 November 2018

Impact of Aromatic Stacking on Glycoside Reactivity: Balancing CH/π and Cation/π Interactions for the Stabilization of Glycosyl-Oxocarbenium Ions

scientific article published on 20 August 2019

Insights into the geometrical features underlying beta-O-GlcNAc glycosylation: water pockets drastically modulate the interactions between the carbohydrate and the peptide backbone

scientific article

Limited flexibility of lactose detected from residual dipolar couplings using molecular dynamics simulations and steric alignment methods

scientific article

Machine intelligence decrypts β-lapachone as an allosteric 5-lipoxygenase inhibitor

scientific article published on 17 July 2018

Modulating weak interactions for molecular recognition: a dynamic combinatorial analysis for assessing the contribution of electrostatics to the stability of CH-π bonds in water

scientific article published on 9 February 2015

Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3

scientific article published on 13 January 2020

Molecular recognition of aminoglycoside antibiotics by bacterial defence proteins: NMR study of the structural and conformational features of streptomycin inactivation by Bacillus subtilis aminoglycoside-6-adenyl transferase

scientific article published in August 2005

Molecular recognition of β-O-GlcNAc glycopeptides by a lectin-like receptor: binding modulation by the underlying Ser or Thr amino acids.

scientific article

Mucin architecture behind the immune response: design, evaluation and conformational analysis of an antitumor vaccine derived from an unnatural MUC1 fragment.

scientific article published on 15 December 2015

Multiple keys for a single lock: the unusual structural plasticity of the nucleotidyltransferase (4')/kanamycin complex

scientific article published in February 2012

NMR-based analysis of aminoglycoside recognition by the resistance enzyme ANT(4'): the pattern of OH/NH3(+) substitution determines the preferred antibiotic binding mode and is critical for drug inactivation.

scientific article published on 26 March 2008

New insights into alpha-GalNAc-Ser motif: influence of hydrogen bonding versus solvent interactions on the preferred conformation.

scientific article published in November 2006

New syntheses of enantiopure 2-methyl isoserines

article published in 2004

Non-natural amino acids as modulating agents of the conformational space of model glycopeptides

scientific article published in January 2008

Observation of the Unbiased Conformers of Putative DNA-Scaffold Ribosugars

scientific article published on 18 February 2020

Preparation and Synthetic Applications of (S)- and (R)-N-Boc-N,O-isopropylidene-alpha-methylserinals: Asymmetric Synthesis of (S)- and (R)-2-Amino-2-methylbutanoic Acids (Iva)

scientific article published on 01 October 1999

Principles of mucin structure: implications for the rational design of cancer vaccines derived from MUC1-glycopeptides.

scientific article published on 12 October 2017

Quaternary chiral β(2,2)-amino acids with pyridinium and imidazolium substituents

scientific article published on 12 October 2012

Quillaja Saponin Variants with Central Glycosidic Linkage Modifications Exhibit Distinct Conformations and Adjuvant Activities

scientific article published on 15 January 2016

Rational design of a Tn antigen mimic

scientific article published on 31 March 2011

Role of aromatic rings in the molecular recognition of aminoglycoside antibiotics: implications for drug design.

scientific article published on September 2010

Role of conserved salt bridges in homeodomain stability and DNA binding

scientific article

S-Michael additions to chiral dehydroalanines as an entry to glycosylated cysteines and a sulfa-Tn antigen mimic

scientific article published on 07 January 2014

SN2 vs E2 on Quaternary Centers: An Easy Approach to Chiral β2,2-Amino Acids from Cyclic Sulfamidates

article by alberto avenoza et al published 2 March 2005 in Phosphorus, Sulfur, and Silicon and the Related Elements

Serine versus threonine glycosylation with α-O-GalNAc: unexpected selectivity in their molecular recognition with lectins.

scientific article published on 8 August 2014

Serine versus threonine glycosylation: the methyl group causes a drastic alteration on the carbohydrate orientation and on the surrounding water shell

scientific article

Site-Selective Modification of Proteins with Oxetanes

scientific article published on 5 March 2017

Solution structures of chemoenzymatically synthesized heparin and its precursors.

scientific article published on 04 September 2008

Stabilizing unusual conformations in small peptides and glucopeptides using a hydroxylated cyclobutane amino acid.

scientific article published on 8 June 2009

Stable Pyrrole-Linked Bioconjugates through Tetrazine-Triggered Azanorbornadiene Fragmentation

scientific article published on 18 February 2020

Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents

scientific article published on 26 October 2016

Structural analysis of a GalNAc-T2 mutant reveals an induced-fit catalytic mechanism for GalNAc-Ts.

scientific article published on 30 March 2018

Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4

scientific article published on 14 September 2018

Structural basis for substrate specificity and catalysis of α1,6-fucosyltransferase

scientific article published on 20 February 2020

Structural basis for the synthesis of the core 1 structure by C1GalT1

scientific article published on 03 May 2022

Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody

scientific article published on 19 November 2020

Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage

scientific article published on 20 February 2019

Structure-based design of highly crowded ribostamycin/kanamycin hybrids as a new family of antibiotics.

scientific article

Substrate-guided front-face reaction revealed by combined structural snapshots and metadynamics for the polypeptide N-acetylgalactosaminyltransferase 2

scientific article

Synthesis and conformational analysis of hybrid α/β-dipeptides incorporating S-glycosyl-β(2,2)-amino acids

scientific article published on 20 November 2014

Synthesis and conformational analysis of neoglycoconjugates derived from O- and S-glucose.

scientific article published on 13 March 2013

Synthesis of Mixed α/β2,2-Peptides by Site-Selective Ring-Opening of Cyclic Quaternary Sulfamidates

scientific article published on 16 November 2015

Synthesis of Nβ-Substituted α,β-Diamino Acids via Stereoselective N-Michael Additions to a Chiral Bicyclic Dehydroalanine

scientific article published on 19 February 2020

Synthesis, conformational analysis and <i>in vivo</i> assays of an anti-cancer vaccine that features an unnatural antigen based on an sp<sup>2</sup>-iminosugar fragment

scientific article published on 27 March 2020

The Plasticity of the Carbohydrate Recognition Domain Dictates the Exquisite Mechanism of Binding of Human Macrophage Galactose-Type Lectin

scientific article published on 01 October 2019

The Unusual Nucleotide Recognition Properties of the Resistance Enzyme ANT(4′): Inorganic Tri/Polyphosphate as a Substrate for Aminoglycoside Inactivation

scientific article published on 01 August 2010

The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer.

scientific article published on 22 November 2017

The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences

scientific article published on 5 December 2017

The nature and sequence of the amino acid aglycone strongly modulates the conformation and dynamics effects of Tn antigen's clusters

scientific article published in January 2009

The pattern of distribution of amino groups modulates the structure and dynamics of natural aminoglycosides: implications for RNA recognition.

scientific article published on 14 February 2007

The use of time-averaged 3JHH restrained molecular dynamics (tar-MD) simulations for the conformational analysis of five-membered ring systems: methodology and applications.

scientific article

Tn Antigen Mimics Based on sp(2)-Iminosugars with Affinity for an anti-MUC1 Antibody

scientific article published on 25 July 2016

Tn Antigen Mimics by Ring-Opening of Chiral Cyclic Sulfamidates with Carbohydrate C1-S- and C1-O-Nucleophiles

scientific article published on 13 April 2018

Toward Enantiomerically Pure β-Seleno-α-amino Acids via Stereoselective <i>Se</i>-Michael Additions to Chiral Dehydroalanines

scientific article published on 29 December 2020

Understanding the unusual regioselectivity in the nucleophilic ring-opening reactions of gem-disubstituted cyclic sulfates. Experimental and theoretical studies

scientific article published on 01 May 2003

Unraveling the Conformational Landscape of Ligand Binding to Glucose/Galactose-Binding Protein by Paramagnetic NMR and MD Simulations

scientific article

Unveiling the activation dynamics of a fold-switch bacterial glycosyltransferase by 19F NMR

scientific article published on 20 May 2020

Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition

scientific article published on 30 July 2018

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