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List of works by Diego Forni

A 175 million year history of T cell regulatory molecules reveals widespread selection, with adaptive evolution of disease alleles.

scientific article published on 23 May 2013

A 6-amino acid insertion/deletion polymorphism in the mucin domain of TIM-1 confers protections against HIV-1 infection.

scientific article

A Common Polymorphism in TLR3 Confers Natural Resistance to HIV-1 Infection

article

A common genetic variant in FOXP2 is associated with language-based learning (dis)abilities: Evidence from two Italian independent samples

scientific article published on 24 April 2017

A functional variant in ERAP1 predisposes to multiple sclerosis

scientific article

A nonsense polymorphism (R392X) in TLR5 protects from obesity but predisposes to diabetes

scientific article

A regulatory polymorphism in HAVCR2 modulates susceptibility to HIV-1 infection

scientific article

A trans-specific polymorphism in ZC3HAV1 is maintained by long-standing balancing selection and may confer susceptibility to multiple sclerosis.

scientific article published on 6 January 2012

ABO histo-blood group might modulate predisposition to Crohn's disease and affect disease behavior.

scientific article

Adaptation of the endemic coronaviruses HCoV-OC43 and HCoV-229E to the human host

scientific article published on 24 June 2021

Albuminoid genes: evolving at the interface of dispensability and selection

scientific article

An evolutionary analysis of antigen processing and presentation across different timescales reveals pervasive selection

scientific article

An evolutionary history of the selectin gene cluster in humans.

scientific article

Analysis of Reptarenavirus genomes indicates different selective forces acting on the S and L segments and recent expansion of common genotypes

scholarly article by Chiara Pontremoli published in October 2018

Ancient Evolution of Mammarenaviruses: Adaptation via Changes in the L Protein and No Evidence for Host-Virus Codivergence.

scientific article published in March 2018

Ancient and recent selective pressures shaped genetic diversity at AIM2-like nucleic acid sensors.

scientific article

Antigenic variation of SARS-CoV-2 in response to immune pressure

scientific article published on 02 December 2020

Coding potential and sequence conservation of SARS-CoV-2 and related animal viruses

scientific article published on 05 May 2020

Computational inference of selection underlying the evolution of the novel coronavirus, SARS-CoV-2

scientific article published on 01 April 2020

Crohn's disease loci are common targets of protozoa-driven selection

scientific article published on 6 February 2013

Determining multiallelic complex copy number and sequence variation from high coverage exome sequencing data

scientific article

Distinct selective forces and Neanderthal introgression shaped genetic diversity at genes involved in neurodevelopmental disorders

scientific article

Diverse selective regimes shape genetic diversity at ADAR genes and at their coding targets

scientific article published on January 2015

Endoplasmic reticulum aminopeptidase 2 haplotypes play a role in modulating susceptibility to HIV infection.

scientific article

Evolution and Genetic Diversity of Primate Cytomegaloviruses

scientific article published on 25 April 2020

Evolution of the rapidly mutating human salivary agglutinin gene (DMBT1) and population subsistence strategy

scientific article published on 6 April 2015

Evolutionary Analysis Provides Insight Into the Origin and Adaptation of HCV.

scientific article

Evolutionary analysis identifies an MX2 haplotype associated with natural resistance to HIV-1 infection.

scientific article published on 14 June 2014

Evolutionary analysis of Old World arenaviruses reveals a major adaptive contribution of the viral polymerase.

scientific article published on 5 August 2017

Evolutionary analysis of the contact system indicates that kininogen evolved adaptively in mammals and in human populations

scientific article published on 16 March 2013

Evolutionary insights into host-pathogen interactions from mammalian sequence data.

scientific article

Evolutionary rates of mammalian telomere-stability genes correlate with karyotype features and female germline expression

article

Extensive Positive Selection Drives the Evolution of Nonstructural Proteins in Lineage C Betacoronaviruses

scientific article published on 20 January 2016

Genetic adaptation of the human circadian clock to day-length latitudinal variations and relevance for affective disorders

scientific article

Genetic conflicts with Plasmodium parasites and functional constraints shape the evolution of erythrocyte cytoskeletal proteins

scientific article published in Scientific Reports

Genetic variability at the TREX1 locus is not associated with natural resistance to HIV-1 infection

article

Geographic structuring and divergence time frame of monkeypox virus in the endemic region

scientific article published on 14 July 2022

Homology‐based classification of accessory proteins in coronavirus genomes uncovers extremely dynamic evolution of gene content

scientific article published in 2022

Identification of a new susceptibility variant for multiple sclerosis in OAS1 by population genetics analysis.

scientific article

Long-standing balancing selection in the THBS4 gene: influence on sex-specific brain expression and gray matter volumes in Alzheimer disease.

scientific article

Mammalian NPC1 genes may undergo positive selection and human polymorphisms associate with type 2 diabetes

scientific article

Molecular Evolution of Human Coronavirus Genomes.

scientific article

Multiple Selected Changes May Modulate the Molecular Interaction between Laverania RH5 and Primate Basigin.

scientific article

Natural Selection at the Brush-Border: Adaptations to Carbohydrate Diets in Humans and Other Mammals.

scientific article published on 28 August 2015

No association of IFI16 (interferon-inducible protein 16) variants with susceptibility to multiple sclerosis

scientific article published on 16 April 2014

Nonstructural Proteins Are Preferential Positive Selection Targets in Zika Virus and Related Flaviviruses

scientific article

OASes and STING: adaptive evolution in concert

scientific article published on 9 March 2015

Origin and dispersal of Hepatitis E virus

scientific article

Past and ongoing adaptation of human cytomegalovirus to its host

scientific article published on 08 May 2020

Positive Selection Drives Evolution at the Host-Filovirus Interaction Surface

scientific article published on 10 August 2016

Positive selection underlies the species-specific binding of Plasmodium falciparum RH5 to human basigin.

scientific article published on 24 August 2015

Possible European Origin of Circulating Varicella Zoster Virus Strains

scientific article published on 01 March 2020

REST, a master regulator of neurogenesis, evolved under strong positive selection in humans and in non human primates.

scientific article published on 25 August 2017

RIG-I-like receptors evolved adaptively in mammals, with parallel evolution at LGP2 and RIG-I.

scientific article published on 7 November 2013

Recent Out-of-Africa Migration of Human Herpes Simplex Viruses

scientific article published on 09 January 2020

Strategy of Human Cytomegalovirus To Escape Interferon Beta-Induced APOBEC3G Editing Activity

scientific article published on 12 September 2018

Susceptibility to type 2 diabetes may be modulated by haplotypes in G6PC2, a target of positive selection.

scientific article

TLR3 Mutations in Adult Patients With Herpes Simplex Virus and Varicella-Zoster Virus Encephalitis.

scientific article

The Diversity of Mammalian Hemoproteins and Microbial Heme Scavengers Is Shaped by an Arms Race for Iron Piracy

scientific article published on 11 September 2018

The evolutionary history of genes involved in spoken and written language: beyond FOXP2.

scientific article

The heptad repeat region is a major selection target in MERS-CoV and related coronaviruses.

scientific article

The influence of DCDC2 risk genetic variants on reading: Testing main and haplotypic effects

scientific article published on 24 May 2018

The mammalian complement system as an epitome of host-pathogen genetic conflicts.

scientific article published on 2 February 2016

The role of READ1 and KIAA0319 genetic variations in developmental dyslexia: testing main and interactive effects

scientific article published on 3 August 2017

Variants in SNAP25 are targets of natural selection and influence verbal performances in women

scientific article

You Will Never Walk Alone: Codispersal of JC Polyomavirus with Human Populations

scientific article published on 01 February 2020

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