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List of works by Adrienne M Gorman

A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy.

scientific article published on 2 December 2014

Antioxidant-mediated inhibition of the heat shock response leads to apoptosis

scientific article published on 01 February 1999

Antiproliferative action of benzodiazepines in cultured brain cells is not mediated through the peripheral-type benzodiazepine acceptor

scientific article published in September 1989

Application of a fluorometric assay to detect caspase activity in thymus tissue undergoing apoptosis in vivo

Binding Analysis of the Inositol-Requiring Enzyme 1 Kinase Domain

scientific article published on 16 October 2018

Cell stress and cell death

scientific article

Cellular longevity: role of apoptosis and replicative senescence

scientific article

Cellular stress responses: cell survival and cell death

scientific article

Challenging the dogmas. .

scientific article published on 01 February 1999

Considerations and recent advances in neuroscience

scientific article published on 01 February 2009

Crosstalk between inflammatory mediators and endoplasmic reticulum stress in liver diseases

scientific article published on 14 November 2018

Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL.

scientific article published on July 2006

Dexamethasone pre-treatment interferes with apoptotic death in glioma cells.

scientific article published in January 2000

Disruption of microRNA biogenesis confers resistance to ER stress-induced cell death upstream of the mitochondrion

scientific article

Effect of Kinase Inhibiting RNase Attenuator (KIRA) Compounds on the Formation of Face-to-Face Dimers of Inositol-Requiring Enzyme 1: Insights from Computational Modeling

scientific article published on 06 November 2019

Effect of functionalized micropatterned PLGA on guided neurite growth

scientific article

Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications

scientific article published on 04 August 2018

Excitatory amino acid-induced cytotoxicity in primary cultures of mouse cerebellar granule cells correlates with elevated, sustained c-fos protoncogene expression

article

Functionality of NGF-protected PC12 cells following exposure to 6-hydroxydopamine

scientific article published on 30 October 2006

Generation of rationally-designed nerve growth factor (NGF) variants with receptor specificity.

scientific article published on 3 November 2017

Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein response

scientific article published on 25 October 2017

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis.

scientific article published on 31 August 2017

Heat shock enhances NGF-induced neurite elongation which is not mediated by Hsp25 in PC12 cells

scientific article published on 20 May 2008

Heat shock protects PC12 cells against MPP+ toxicity

scientific article

Heat shock protein 27 in neuronal survival and neurite outgrowth

scientific article published on 26 February 2009

Heat shock protein 70 reduces α-synuclein-induced predegenerative neuronal dystrophy in the α-synuclein viral gene transfer rat model of Parkinson's disease.

scientific article published on 27 November 2013

Homology model of the human tRNA splicing ligase RtcB.

scientific article published on 13 July 2017

Hsp27 inhibits 6-hydroxydopamine-induced cytochrome c release and apoptosis in PC12 cells

scientific article published in February 2005

Hypoxia induces neurite outgrowth in PC12 cells that is mediated through adenosine A2A receptors

scientific article published in January 2005

Inhibition by anandamide of 6-hydroxydopamine-induced cell death in PC12 cells.

scientific article

Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy

scientific article published in Nature Communications

Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β

scientific article published on 16 August 2019

Involvement of Akt in neurite outgrowth

scientific article published on 06 June 2009

L-TRANs-Pyrrolidine-2,4-dicarboxylate and cis-1-aminocyclobutane-1, 3-dicarboxylate behave as transportable, competitive inhibitors of the high-affinity glutamate transporters

scientific article published on 01 January 1994

Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinson's disease in the rat.

scientific article published on 25 January 2010

Merits and pitfalls of conventional and covalent docking in identifying new hydroxyl aryl aldehyde like compounds as human IRE1 inhibitors

scientific article published on 04 March 2019

Modulation by ionotropic excitatory amino acids and potassium of (+/-)-1-aminocyclopentane-trans-1,3-dicarboxylic acid-stimulated phosphoinositide hydrolysis in mouse cerebellar granule cells.

scientific article published on December 1995

Nerve growth factor (NGF)-mediated regulation of p75(NTR) expression contributes to chemotherapeutic resistance in triple negative breast cancer cells

scientific article published on 27 August 2016

Nerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrion via regulation of Bim

scientific journal article

Nerve growth factor in cancer cell death and survival

scientific article published on February 2011

Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner. ⬇️

scientific article

Neuronal cell death in neurodegenerative diseases: recurring themes around protein handling

scientific article published on 27 June 2008

Neurotrophins and B-cell malignancies

scientific article published on 23 September 2015

On the role of Hsp27 in regulating apoptosis

scientific article (publication date: 2003)

RIP2 enhances cell survival by activation of NF-ĸB in triple negative breast cancer cells

scientific article published on 5 February 2018

Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer

scientific article published on 06 May 2022

Regulation of lipid metabolism by the unfolded protein response

scientific article published on 04 January 2021

Stress management at the ER: regulators of ER stress-induced apoptosis

scientific article published on 17 February 2012

Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress

scientific article published on 28 September 2012

Sulphur-containing excitatory amino acid-stimulated inositol phosphate formation in primary cultures of cerebellar granule cells is mediated predominantly by N-methyl-D-aspartate receptors

scientific article

Sustained c-fos expression is associated with excitotoxicity during the development of neuronal cells in vitro

scientific article published in February 1996

Targeting the angio-proteostasis network: Combining the forces against cancer

scientific article published on 21 July 2016

Targeting the endoplasmic reticulum-stress response as an anticancer strategy

scientific article published on 14 October 2009

The Unfolded Protein Response in Breast Cancer

scientific article published on 21 September 2018

The eIF2α kinases: their structures and functions

scientific article published on 26 January 2013

The effect of laminin peptide gradient in enzymatically cross-linked collagen scaffolds on neurite growth

scientific article published in February 2010

The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats

scientific article published on October 2010

The effects of the peripheral-type benzodiazepine acceptor ligands, Ro 5-4864 and PK 11195, on mitochondrial respiration

scientific article published on March 1, 1992

The integrated stress response.

scientific article published on 14 September 2016

The novel toluidine sulphonamide EL102 shows pre-clinical in vitro and in vivo activity against prostate cancer and circumvents MDR1 resistance

scientific article published on 19 September 2013

The repression of apoptosis by activated abl oncogenes in chronic myelogenous leukaemia.

scientific article

The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress.

scientific article published on 29 February 2012

Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders

scientific article published on October 2011

Use of flow cytometry techniques in studying mechanisms of apoptosis in leukemic cells ⬇️

scientific article published on October 1, 1997

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